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Journal Articles

Abstract CT178: Phase 1 trial of PF-07799933 (ARRY-440), a next-generation BRAF inhibitor, for BRAF-mutant cancers

Free
Rona Yaeger, Meredith McKean, Rizwan Haq, Joseph T. Beck, Matthew H. Taylor, Jonathan Cohen, Daniel Bowles, Shirish M. Gadgeel, Catalin Mihalcioiu, Kyriakos P. Papadopoulos, Eli L. Diamond, Keren B. Sturtz, Gang Feng, Stefanie K. Drescher, Micaela B. Reddy, Bhaswati Sengupta, Arnab K. Maity, Suzy A. Brown, Anurag Singh, Eric N. Brown, Brian R. Baer, Jim Wong, Tung-Chung Mou, Wen I. Wu, Dean Kahn, Sunyana Gadal, Neal Rosen, John J. Gaudino, Patrice A. Lee, Dylan P. Hartley, Stephen Michael Rothenberg
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT178.
https://doi.org/10.1158/1538-7445.AM2024-CT178
Published: 05 April 2024
View articletitled, Abstract CT178: Phase 1 trial of PF-07799933 (ARRY-440), a next-generation BRAF inhibitor, for BRAF-mutant cancers
Journal Articles

Abstract 1706: A non-canonical MiT/TFE-dependent NRF2 program is a druggable vulnerability in multiple cancer types

Free
Xinbo Luo, Bart Lutterbach, Priya Pancholi, Yeon Sook Choi, Xiao Liu, Phillip Munson, Saqib Faisal, David A. Whipple, Robert A. Smith, Warren S. Weiner, David K. Johnson, Myriam Boukhali, Nicole S. Persky, Matthew G. Rees, Shunsuke Kitajima, David Barbie, Anuradha Roy, Michael Baltezor, Lian Rajewski, William McGuinness, John Haslam, Ananthan Sadagopan, Charles H. Yoon, Cory M. Johannessen, Christine G. Lian, Jason L. Hornick, Srinivas R. Viswanathan, David Liu, Vicki Nienaber, Wilhelm Haas, Frank J. Schoenen, David E. Fisher, Rizwan Haq
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1706.
https://doi.org/10.1158/1538-7445.AM2023-1706
Published: 04 April 2023
View articletitled, Abstract 1706: A non-canonical MiT/TFE-dependent NRF2 program is a druggable vulnerability in multiple cancer types
Journal Articles

Abstract 965: Genomic heterogeneity and ploidy identify patients with intrinsic resistance to PD-1 blockade in metastatic melanoma

Free
Giuseppe Tarantino, Cora A. Ricker, Annette Wang, Will Ge, Amy Y. Huang, Shariq Madha, Jiajia Chen, Yingxiao Shi, Dennie T. Frederick, Samuel Freeman, Marta M. Holovatska, Michael P. Manos, Lisa Zimmer, Alexander Rösch, Anne Zaremba, Brendan Reardon, Jihye Park, Haitham Elmarakeby, Bastian Schilling, Anita Giobbie-Hurder, Natalie Vokes, Elizabeth I. Buchbinder, Keith Flaherty, Rizwan Haq, Catherine Wu, Genevieve Boland, F. Stephen Hodi, Eliezer Van Allen, Dirk Schadendorf, David Liu
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 965.
https://doi.org/10.1158/1538-7445.AM2023-965
Published: 04 April 2023
View articletitled, Abstract 965: Genomic heterogeneity and ploidy identify patients with intrinsic resistance to PD-1 blockade in metastatic melanoma
Journal Articles

Abstract 2846: Stereotypic patterns and genomic correlates of organotropism in metastatic melanoma

Free
William H. Ge, Giuseppe Tarantino, Emily Robitschek, Michael P. Manos, Lauren Eastman, Olivia Ouyang, Patrick Ott, Ann W. Silk, Osama E. Rahma, Alexander Gusev, Rizwan Haq, Elizabeth I. Buchbinder, Megan L. Insco, Stephen Hodi, Eliezer Van Allen, David Liu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2846.
https://doi.org/10.1158/1538-7445.AM2021-2846
Published: 01 July 2021
View articletitled, Abstract 2846: Stereotypic patterns and genomic correlates of organotropism in metastatic melanoma
Journal Articles

Abstract 62: Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies

Free
Joan Montero, Cecile Gstalder, Daniel J. Kim, Dorota Sadowicz, Wayne Miles, Michael Manos, Justin R. Cidado, J. Paul Secrist, Adriana E. Tron, Keith Flaherty, F. Stephen Hodi, Charles H. Yoon, Anthony Letai, David E. Fisher, Rizwan Haq
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 62.
https://doi.org/10.1158/1538-7445.AM2020-62
Published: 15 August 2020
View articletitled, Abstract 62: Destabilization of NOXA mRNA as a common resistance mechanism to targeted therapies
Journal Articles

Abstract 1698: Loss of MHC-I expression is associated with altered immune microenvironment and decreased response to PD-1 checkpoint inhibition

Free
Cecile Gstalder, Priya Pancholi, Dorota Sadowicz, Rizwan Haq
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1698.
https://doi.org/10.1158/1538-7445.AM2018-1698
Published: 01 July 2018
View articletitled, Abstract 1698: Loss of MHC-I expression is associated with altered immune microenvironment and decreased response to PD-1 checkpoint inhibition
Journal Articles

Abstract 3491: Rational combination of targeted agents and BH3 mimetics to improve cancer treatment

Free
Joan Montero, Dorota E. Sadowicz, Jeremy Ryan, Charles H. Yoon, Rizwan Haq, Anthony Letai
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3491.
https://doi.org/10.1158/1538-7445.AM2016-3491
Published: 15 July 2016
View articletitled, Abstract 3491: Rational combination of targeted agents and BH3 mimetics to improve cancer treatment
Journal Articles

Constitutive p38HOG Mitogen-activated Protein Kinase Activation Induces Permanent Cell Cycle Arrest and Senescence

Free
Rizwan Haq, James D. Brenton, Mark Takahashi, Dina Finan, Robert Rottapel, Brent Zanke
Journal: Cancer Research
Cancer Res (2002) 62 (17): 5076–5082.
Published: 01 September 2002
View articletitled, Constitutive p38HOG Mitogen-activated Protein Kinase Activation Induces Permanent Cell Cycle Arrest and Senescence
Open the PDF for Constitutive p38HOG Mitogen-activated Protein Kinase Activation Induces Permanent Cell Cycle Arrest and Senescence in another window
Journal Articles

Identification of NKIAMRE, the Human Homologue to the Mitogen-activated Protein Kinase-/Cyclin-dependent Kinase-related Protein Kinase NKIATRE, and Its Loss in Leukemic Blasts with Chromosome Arm 5q Deletion

Free
Michael Midmer, Rizwan Haq, Jeremy A. Squire, Brent W. Zanke
Journal: Cancer Research
Cancer Res (1999) 59 (16): 4069–4074.
Published: 15 August 1999
View articletitled, Identification of NKIAMRE, the Human Homologue to the Mitogen-activated Protein Kinase-/Cyclin-dependent Kinase-related Protein Kinase NKIATRE, and Its Loss in Leukemic Blasts with Chromosome Arm 5q Deletion
Open the PDF for Identification of NKIAMRE, the Human Homologue to the Mitogen-activated Protein Kinase-/Cyclin-dependent Kinase-related Protein Kinase NKIATRE, and Its Loss in Leukemic Blasts with Chromosome Arm 5q Deletion in another window