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Journal Articles

Abstract PO5-15-07: Integrative proteomics, phosphoproteomics, and RNA profiling revealed novel timeline-dependent vulnerabilities in HER2-positive breast cancer

Christina Wei, Lixin Yang, Krystine Mansfield, Jessica Liu, Ritin Sharma, Russell Rockne, Raju Pillai, Patrick Pirrotte, Joanne Mortimer
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO5-15-07.
https://doi.org/10.1158/1538-7445.SABCS23-PO5-15-07
Published: 02 May 2024
View article titled, Abstract PO5-15-07: Integrative proteomics, phosphoproteomics, and RNA profiling revealed novel timeline-dependent vulnerabilities in HER2-positive breast cancer
Journal Articles

Abstract 2013: Integrated proteomic analysis identifies four distinct subtypes of high-risk neuroblastoma

Kristin L. Leskoske, Sara A. Byron, Seema Plaisier, Apurva M. Hegde, Krystine Garcia-Mansfield, Ritin Sharma, Genevieve Bergendahl, Abhinav Nagulapally, William Ferguson, Jaqueline Kraveka, Javier Oesterheld, William P. Hendricks, Giselle L. Saulnier Sholler, Jeffrey M. Trent, Patrick Pirrotte
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2013.
https://doi.org/10.1158/1538-7445.AM2022-2013
Published: 15 June 2022
View article titled, Abstract 2013: Integrated proteomic analysis identifies four distinct subtypes of high-risk neuroblastoma
Journal Articles

Abstract 318: Multi-omics to edge into precision medicine for DIPG

Nanyun Tang, Kristin Leskoske, Krystine Garcia-Mansfield, Ritin Sharma, Hannah Tolson, Patrick Pirrotte, Michael E. Berens
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 318.
https://doi.org/10.1158/1538-7445.AM2021-318
Published: 01 July 2021
View article titled, Abstract 318: Multi-omics to edge into precision medicine for DIPG
Journal Articles

Abstract 2534: Underlying mechanism of response to neddylation inhibition in a subset of glioblastoma

Shayesteh Ferdosi, Brett Taylor, Matthew Lee, Nanyun Tang, Sen Peng, Rita Bybee, George Reid, Lauren Hartman, Krystine Garcia-Mansfield, Ritin Sharma, Patrick Pirrotte, Frank Furnari, Harshil Dhruv, Michael Berens
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2534.
https://doi.org/10.1158/1538-7445.AM2021-2534
Published: 01 July 2021
View article titled, Abstract 2534: Underlying mechanism of response to neddylation inhibition in a subset of glioblastoma
Journal Articles

Abstract LB-038: Novel functional insights revealed by distinct protein-protein interactions of the residual SWI/SNF complex in SMARCA4-deficient small cell carcinoma of the ovary, hypercalcemic type

Elizabeth Raupach, Krystine Garcia-Mansfield, Ritin Sharma, Apurva Hegde, Victoria David-Dirgo, Yemin Wang, Chae Young Shin, Lan Tao, Salvatore Facista, Rayvon Moore, Jessica Lang, Victoria Zismann, Krystal Orlando, Monique Spillman, Anthony Karnezis, Lynda Bennett, David Huntsman, Jeffrey Trent, William Hendricks, Bernard Weissman, Patrick Pirrotte
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): LB-038.
https://doi.org/10.1158/1538-7445.AM2020-LB-038
Published: 15 August 2020
View article titled, Abstract LB-038: Novel functional insights revealed by distinct protein-protein interactions of the residual SWI/SNF complex in SMARCA4-deficient small cell carcinoma of the ovary, hypercalcemic type
Journal Articles

Abstract 248: Dynamic multi-OMICS analysis of glioblastoma cells reveals context of vulnerability to neddylation inhibition by pevonedistat

Shayesteh R. Ferdosi, Brett Taylor, Nanyun Tang, Rita Bybee, Sen Peng, Victoria David-Dirgo, Krystine Garcia-Mansfield, Ritin Sharma, Patrick Pirrotte, Michael Berens, Harshil Dhruv
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 248.
https://doi.org/10.1158/1538-7445.AM2019-248
Published: 01 July 2019
View article titled, Abstract 248: Dynamic multi-OMICS analysis of glioblastoma cells reveals context of vulnerability to neddylation inhibition by pevonedistat
Journal Articles

Abstract 3488: Loss of nuclear alpha-catenin is associated with race, aggressive disease, and chemoresistance in triple negative breast cancer

Rania Bassiouni, Yunchi Li, Victoria David-Dirgo, Krystine Garcia-Mansfield, Ritin Sharma, Patrick Pirrotte, Nasreen Vohra, Sandeep Singhal, Kevin Gardner, John D. Carpten
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3488.
https://doi.org/10.1158/1538-7445.AM2019-3488
Published: 01 July 2019
View article titled, Abstract 3488: Loss of nuclear alpha-catenin is associated with race, aggressive disease, and chemoresistance in triple negative breast cancer
Journal Articles

HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy

Michael F. Emmons, Fernanda Faião-Flores, Ritin Sharma, Ram Thapa, Jane L. Messina, Jurgen C. Becker, Dirk Schadendorf, Edward Seto, Vernon K. Sondak, John M. Koomen, Yian A. Chen, Eric K. Lau, Lixin Wan, Jonathan D. Licht, Keiran S.M. Smalley
Journal: Cancer Research
Cancer Res (2019) 79 (11): 2947–2961.
https://doi.org/10.1158/0008-5472.CAN-19-0040
Published: 03 June 2019
View article titled, HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy
Open the PDF for HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy in another window
Includes: Supplementary data
Journal Articles

Abstract 3025: Ligand-independent EphA2 signaling drives an amoeboid phenotype that promotes melanoma brain metastasis development

Chao Zhang, Inna Smalley, Ritin Sharma, Michael Emmons, Jane Messina, John Koomen, Keiran Smalley
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3025.
https://doi.org/10.1158/1538-7445.AM2018-3025
Published: 01 July 2018
View article titled, Abstract 3025: Ligand-independent EphA2 signaling drives an amoeboid phenotype that promotes melanoma brain metastasis development
Journal Articles

Abstract 2705: Functional proteomics to reveal distinct signature for acute myeloid leukemia subtypes

Patrick Pirrotte, Victoria David, Ritin Sharma, Daniel H. Wai, Cristina Tognon, Brian Druker, Eiman A. Aleem
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2705.
https://doi.org/10.1158/1538-7445.AM2018-2705
Published: 01 July 2018
View article titled, Abstract 2705: Functional proteomics to reveal distinct signature for acute myeloid leukemia subtypes
Journal Articles

Abstract 294: The role of the histone deacetylase HDAC 8 in mediating BRAF/MEK inhibitor metastatic dissemination and resistance

Michael Emmons, Rashed Rab, Ritin Sharma, John Koomen, Keiran Smalley
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 294.
https://doi.org/10.1158/1538-7445.AM2016-294
Published: 15 July 2016
View article titled, Abstract 294: The role of the histone deacetylase HDAC 8 in mediating BRAF/MEK inhibitor metastatic dissemination and resistance
Journal Articles

Abstract 2006: Kinases and adaptive signaling contribute to drug resistance in BRAF mutant melanoma

Ritin Sharma, Manali Phadke, David Britton, Ian Pike, Keiran Smalley, John M. Koomen
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2006.
https://doi.org/10.1158/1538-7445.AM2015-2006
Published: 01 August 2015
View article titled, Abstract 2006: Kinases and adaptive signaling contribute to drug resistance in BRAF mutant melanoma