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Rita Derua
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Journal Articles

Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition

Free
Lisa M. Butler, Chui Yan Mah, Jelle Machiels, Andrew D. Vincent, Swati Irani, Shadrack M. Mutuku, Xander Spotbeen, Muralidhararao Bagadi, David Waltregny, Max Moldovan, Jonas Dehairs, Frank Vanderhoydonc, Katarzyna Bloch, Rajdeep Das, Jurgen Stahl, James G. Kench, Thomas Gevaert, Rita Derua, Etienne Waelkens, Zeyad D. Nassar, Luke A. Selth, Paul J. Trim, Marten F. Snel, David J. Lynn, Wayne D. Tilley, Lisa G. Horvath, Margaret M. Centenera, Johannes V. Swinnen
Journal: Cancer Research
Cancer Res (2021) 81 (19): 4981–4993.
https://doi.org/10.1158/0008-5472.CAN-20-3863
Published: 01 October 2021
View articletitled, Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition
Open the PDF for Lipidomic Profiling of Clinical Prostate Cancer Reveals Targetable Alterations in Membrane Lipid Composition in another window
Includes: Supplementary data
Journal Articles

ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer

Free
Margaret M. Centenera, Julia S. Scott, Jelle Machiels, Zeyad D. Nassar, Deanna C. Miller, Irene Zinonos, Jonas Dehairs, Ingrid J.G. Burvenich, Giorgia Zadra, Paolo M. Chetta, Clyde Bango, Emma Evergren, Natalie K. Ryan, Joanna L. Gillis, Chui Yan Mah, Terence Tieu, Adrienne R. Hanson, Ryan Carelli, Katarzyna Bloch, Vasilios Panagopoulos, Etienne Waelkens, Rita Derua, Elizabeth D. Williams, Andreas Evdokiou, Anna Cifuentes-Rius, Nicolas H. Voelcker, Ian G. Mills, Wayne D. Tilley, Andrew M. Scott, Massimo Loda, Luke A. Selth, Johannes V. Swinnen, Lisa M. Butler
Journal: Cancer Research
Cancer Res (2021) 81 (7): 1704–1718.
https://doi.org/10.1158/0008-5472.CAN-20-2511
Published: 01 April 2021
View articletitled, ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer
Open the PDF for ELOVL5 Is a Critical and Targetable Fatty Acid Elongase in Prostate Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract B08: Differential regulation of Protein Kinase D isoforms in oxidative stress conditions via tyrosine phosphorylation in the activation segment

Free
Mathias Cobbaut, Rita Derua, Etienne Waelkens, Peter Störz, Veerle Janssens, Johan Van Lint
Journal: Cancer Research
Cancer Res (2017) 77 (22_Supplement): B08.
https://doi.org/10.1158/1538-7445.NEWFRONT17-B08
Published: 14 November 2017
View articletitled, Abstract B08: Differential regulation of Protein Kinase D isoforms in oxidative stress conditions via tyrosine phosphorylation in the activation segment
Journal Articles

Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth

Free
Dorien Haesen, Layka Abbasi Asbagh, Rita Derua, Antoine Hubert, Stefanie Schrauwen, Yana Hoorne, Frédéric Amant, Etienne Waelkens, Anna Sablina, Veerle Janssens
Journal: Cancer Research
Cancer Res (2016) 76 (19): 5719–5731.
https://doi.org/10.1158/0008-5472.CAN-15-3342
Published: 02 October 2016
View articletitled, Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth
Open the PDF for Recurrent PPP2R1A Mutations in Uterine Cancer Act through a Dominant-Negative Mechanism to Promote Malignant Cell Growth in another window
Includes: Supplementary data
Journal Articles

Abstract LB-356: An siRNA screen identifies Rsk1 as a key modulator of lung cancer metastasis

Free
Romain Lara, Francesco A. Mauri, Harriet Taylor, Rita Derua, Alice Shia, Colin Gray, Alastair Nicols, Robert J. Shiner, Edward Schofield, Paul A. Bates, Etienne Waelkens, Maggie Dallman, Jonathan Lamb, Daniel Zicha, Julian Downward, Michael J. Seckl, Olivier E. Pardo
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-356.
https://doi.org/10.1158/1538-7445.AM2011-LB-356
Published: 15 April 2011
View articletitled, Abstract LB-356: An siRNA screen identifies Rsk1 as a key modulator of lung cancer metastasis
Journal Articles

De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

Free
Evelien Rysman, Koen Brusselmans, Katryn Scheys, Leen Timmermans, Rita Derua, Sebastian Munck, Paul P. Van Veldhoven, David Waltregny, Veerle W. Daniëls, Jelle Machiels, Frank Vanderhoydonc, Karine Smans, Etienne Waelkens, Guido Verhoeven, Johannes V. Swinnen
Journal: Cancer Research
Cancer Res (2010) 70 (20): 8117–8126.
https://doi.org/10.1158/0008-5472.CAN-09-3871
Published: 13 October 2010
View articletitled, De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation
Open the PDF for De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation in another window
Includes: Supplementary data
Journal Articles

Mimicry of a Cellular Low Energy Status Blocks Tumor Cell Anabolism and Suppresses the Malignant Phenotype

Free
Johannes V. Swinnen, Annelies Beckers, Koen Brusselmans, Sophie Organe, Joanna Segers, Leen Timmermans, Frank Vanderhoydonc, Ludo Deboel, Rita Derua, Etienne Waelkens, Ellen De Schrijver, Tine Van de Sande, Agnès Noël, Fabienne Foufelle, Guido Verhoeven
Journal: Cancer Research
Cancer Res (2005) 65 (6): 2441–2448.
https://doi.org/10.1158/0008-5472.CAN-04-3025
Published: 21 March 2005
View articletitled, Mimicry of a Cellular Low Energy Status Blocks Tumor Cell Anabolism and Suppresses the Malignant Phenotype
Open the PDF for Mimicry of a Cellular Low Energy Status Blocks Tumor Cell Anabolism and Suppresses the Malignant Phenotype in another window