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Rik J. Scheper
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Journal Articles

Abstract 4692: Local adjuvant treatment of clinical stage I-II melanoma with low dose CpG-B and/or GM-CSF: Long-term follow-up of three randomized controlled phase II trials

Free
Bas D. Koster, Mari F. van den Hout, Berbel J. Sluijter, Barbara G. Molenkamp, Ronald J. Vuylsteke, Arnold Baars, Paul A. van Leeuwen, Rik J. Scheper, Monique P. van den Tol, Alfons J. van den Eertwegh, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4692.
https://doi.org/10.1158/1538-7445.AM2017-4692
Published: 01 July 2017
View articletitled, Abstract 4692: Local adjuvant treatment of clinical stage I-II melanoma with low dose CpG-B and/or GM-CSF: Long-term follow-up of three randomized controlled phase II trials
Journal Articles

Abstract 496: Inflammatory responses with infiltrating DC and functional cytotoxic T lymphocytes in the dermal vaccination sites of GVAX/ipilimumab treated prostate cancer patients.

Free
Saskia J. Santegoets, Leonieke JJ van Mens, Jeroen AM Beliën, Anita GM Stam, Sinead M. Lougheed, Rik J. Scheper, Shabnam Samiei, Helen Gall, Karin Jooss, Jean-Marie Cuillerot, Natalie Sacks, Kirsten Hege, Winald R. Gerritsen, Alfons JM van den Eertwegh, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 496.
https://doi.org/10.1158/1538-7445.AM2013-496
Published: 15 April 2013
View articletitled, Abstract 496: Inflammatory responses with infiltrating DC and functional cytotoxic T lymphocytes in the dermal vaccination sites of GVAX/ipilimumab treated prostate cancer patients.
Journal Articles

Abstract 1229: Pre-existing NY-ESO-1-specific T cell reactivity is associated with improved clinical outcome in castration resistant prostate cancer patients treated with Prostate GVAX and ipilimumab.

Free
Anita GM Stam, Saskia JAM Santegoets, Alfons JM van den Eertwegh, Rik J. Scheper, Sinéad M. Lougheed, Helen Gall, Karin Jooss, Natalie Sacks, Thomas Harding, Kristen Hege, Israel Lowy, Sacha Gnjatic, Jedd D. Wolchok, Winald R. Gerritsen, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1229.
https://doi.org/10.1158/1538-7445.AM2013-1229
Published: 15 April 2013
View articletitled, Abstract 1229: Pre-existing NY-ESO-1-specific T cell reactivity is associated with improved clinical outcome in castration resistant prostate cancer patients treated with Prostate GVAX and ipilimumab.
Journal Articles

Abstract 3533: Acquisition of antigen presenting cell functions by Vγ9Vα2-T cells requires trogocytosis

Free
Famke L. Schneiders, Saskia J.A.M. Santegoets, Rik J. Scheper, Henk M.W. Verheul, Marc Bonneville, Emmanuel Scotet, Tanja D. de Gruijl, Hans J. van der Vliet
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3533.
https://doi.org/10.1158/1538-7445.AM2012-3533
Published: 15 April 2012
View articletitled, Abstract 3533: Acquisition of antigen presenting cell functions by Vγ9Vα2-T cells requires trogocytosis
Journal Articles

Potent Antitumor Immunity Generated by a CD40-Targeted Adenoviral Vaccine

Free
Basav N. Hangalapura, Dinja Oosterhoff, Jan de Groot, Louis Boon, Thomas Tüting, Alfons J. van den Eertwegh, Winald R. Gerritsen, Victor W. van Beusechem, Alexander Pereboev, David T. Curiel, Rik J. Scheper, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2011) 71 (17): 5827–5837.
https://doi.org/10.1158/0008-5472.CAN-11-0804
Published: 30 August 2011
View articletitled, Potent Antitumor Immunity Generated by a CD40-Targeted Adenoviral Vaccine
Open the PDF for Potent Antitumor Immunity Generated by a CD40-Targeted Adenoviral Vaccine in another window
Includes: Supplementary data
Journal Articles

Abstract 5512: Immune correlates of clinical response and survival in castration-resistant prostate cancer patients treated with prostate GVAX and anti-CTLA4 immunotherapy

Free
Saskia J.A.M. Santegoets, Alfons J.M. van den Eertwegh, Anita G.M. Stam, Rik J. Scheper, Sinéad M. Lougheed, Petra E.T. Scholten, Mary B.M.E. von Blomberg, Helen Gall, Karin Jooss, Minh C. Nguyen, Tom Harding, Natalie Sacks, Kristen Hege, Israel Lowy, Kevin Chin, Winald R. Gerritsen, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5512.
https://doi.org/10.1158/1538-7445.AM2011-5512
Published: 15 April 2011
View articletitled, Abstract 5512: Immune correlates of clinical response and survival in castration-resistant prostate cancer patients treated with prostate GVAX and anti-CTLA4 immunotherapy
Journal Articles

Abstract 5588: T cell activation in relation to clinical responsiveness in patients with metastatic hormone-refractory prostate cancer receiving combined Prostate GVAX and anti-CTLA4 immunotherapy

Free
Saskia J. Santegoets, Anita G. Stam, Rik J. Scheper, Petra E. Scholten, B M. von Blomberg, Helen Gall, Karin Jooss, Nathalie Sacks, Tom Harding, Kristen Hege, Israel Lowy, Alfons J. van den Eertwegh, Winald R. Gerritsen, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5588.
https://doi.org/10.1158/1538-7445.AM10-5588
Published: 15 April 2010
View articletitled, Abstract 5588: T cell activation in relation to clinical responsiveness in patients with metastatic hormone-refractory prostate cancer receiving combined Prostate GVAX and anti-CTLA4 immunotherapy
Journal Articles

Abstract 5618: Arming the melanoma sentinel lymph node against tumor spread: The effects of local administration of combined low-dose CpG-B PF-3512676 and GM-CSF

Free
Mari F.c.m. van den Hout, Berbel J.r. Sluijter, Saskia J.a.m. Santegoets, Alfons J.m. van den Eertwegh, Sybren Meijer, Petrousjka van den Tol, Paul A.m. van Leeuwen, Rik J. Scheper, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5618.
https://doi.org/10.1158/1538-7445.AM10-5618
Published: 15 April 2010
View articletitled, Abstract 5618: Arming the melanoma sentinel lymph node against tumor spread: The effects of local administration of combined low-dose CpG-B PF-3512676 and GM-CSF
Journal Articles

Abstract 2934: Increased type-2 T cell rates and coincidence of Th17 spikes with autoimmune events and PSA declines upon combined prostate GVAX and anti-CTLA4 immunotherapy

Free
Anita GM Stam, Saskia JAM Santegoets, Rik J. Scheper, Sinead M. Lougheed, Helen Gall, Karin Jooss, Natalie Sacks, Kristen Hege, Israel Lowy, Winald R. Gerritsen, Alfons JM van den Eertwegh, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2934.
https://doi.org/10.1158/1538-7445.AM10-2934
Published: 15 April 2010
View articletitled, Abstract 2934: Increased type-2 T cell rates and coincidence of Th17 spikes with autoimmune events and PSA declines upon combined prostate GVAX and anti-CTLA4 immunotherapy
Journal Articles

Abstract 2538: Dendritic and T cell functions in patients with metastatic hormone-refractory prostate cancer treated with GVAX immunotherapy for prostate cancer and ipilimumab

Free
Saskia J.A.M. Santegoets, Alfons J.M. van den Eertwegh, Sinead M. Lougheed, Anita G.M. Stam, Helen Gall, Petra E.T. Scholten, Mary B.E. von Blomberg, Erik Hooijberg, Karin Jooss, Nathalie Sacks, Minh Nguyen, Thomas Harding, Thomas Harding, Kristen Hege, Israel Lowy, Winald R. Gerritsen, Rik J. Scheper, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2538.
https://doi.org/10.1158/1538-7445.AM2008-2538
Published: 15 May 2008
View articletitled, Abstract 2538: Dendritic and T cell functions in patients with metastatic hormone-refractory prostate cancer treated with GVAX immunotherapy for prostate cancer and ipilimumab
Journal Articles

Multidrug resistance-related ATP-binding cassette (ABC) transporters in dendritic cell functions

Free
Rieneke Van de Ven, Mariska C. De Jong, Anneke W. Reurs, Antoinet J. Schoonderwoerd, Gerrit Jansen, Jan H. Hooijberg, George L. Scheffer, Tanja D. De Gruijl, Rik J. Scheper
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1145.
Published: 15 April 2006
View articletitled, Multidrug resistance-related ATP-binding cassette (ABC) transporters in dendritic cell functions
Journal Articles

Prognostic value of circulating invariant NKT cell levels in patients with squamous cell carcinoma of the head and neck

Free
Hetty J. Bontkes, Johan W. Molling, Jacqueline Langius, Johannes A. Langendijk, René Leemans, Hans J. Van der Vliet, Rik J. Scheper, Mary Von Blomberg, Alfons J. Van Den Eertwegh
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 150.
Published: 15 April 2006
View articletitled, Prognostic value of circulating invariant NKT cell levels in patients with squamous cell carcinoma of the head and neck
Journal Articles

Interstitial DC and Langerhans cells, derived from the human MUTZ-3 cell line, display lymph node migration and tumor-specific CTL priming capabilities

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Saskia J. Santegoets, Anita G. Stam, Allan J. Masterson, Marco W. Schreurs, Esther W. Kueter, Alfons J. Van Den Eertwegh, Erik Hooijberg, Rik J. Scheper, Tanja D. De Gruijl
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 740.
Published: 15 April 2006
View articletitled, Interstitial DC and Langerhans cells, derived from the human MUTZ-3 cell line, display lymph node migration and tumor-specific CTL priming capabilities
Journal Articles

The effects of pre-operative administration of CpG 7909 on dendritic and T cell subsets in the sentinel lymph node of stage I/II melanoma patients

Free
Tanja D. De Gruijl, Barbara G. Molenkamp, Alfons J. Van Den Eertwegh, Pepijn G. Wijnands, Sybren Meijer, Rik J. Scheper, Paul A. Van Leeuwen
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 941–942.
Published: 15 April 2006
View articletitled, The effects of pre-operative administration of CpG 7909 on dendritic and T cell subsets in the sentinel lymph node of stage I/II melanoma patients
Journal Articles

Local Administration of Granulocyte/Macrophage Colony-stimulating Factor Increases the Number and Activation State of Dendritic Cells in the Sentinel Lymph Node of Early-Stage Melanoma

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Ronald J. C. L. M. Vuylsteke, Barbara G. Molenkamp, Hester A. Gietema, Paul A. M. van Leeuwen, Pepijn G. J. T. B. Wijnands, Wim Vos, Paul J. van Diest, Rik J. Scheper, Sybren Meijer, Tanja D. de Gruijl
Journal: Cancer Research
Cancer Res (2004) 64 (22): 8456–8460.
https://doi.org/10.1158/0008-5472.CAN-03-3251
Published: 17 November 2004
View articletitled, Local Administration of Granulocyte/Macrophage Colony-stimulating Factor Increases the Number and Activation State of Dendritic Cells in the Sentinel Lymph Node of Early-Stage Melanoma
Open the PDF for Local Administration of Granulocyte/Macrophage Colony-stimulating Factor Increases the Number and Activation State of Dendritic Cells in the Sentinel Lymph Node of Early-Stage Melanoma in another window
Journal Articles

Efflux Kinetics and Intracellular Distribution of Daunorubicin Are Not Affected by Major Vault Protein/Lung Resistance-Related Protein (Vault) Expression

Free
Arend van Zon, Marieke H. Mossink, Martijn Schoester, Rik J. Scheper, Pieter Sonneveld, Erik A. C. Wiemer
Journal: Cancer Research
Cancer Res (2004) 64 (14): 4887–4892.
https://doi.org/10.1158/0008-5472.CAN-03-3891
Published: 15 July 2004
View articletitled, Efflux Kinetics and Intracellular Distribution of Daunorubicin Are Not Affected by Major Vault Protein/Lung Resistance-Related Protein (Vault) Expression
Open the PDF for Efflux Kinetics and Intracellular Distribution of Daunorubicin Are Not Affected by Major Vault Protein/Lung Resistance-Related Protein (Vault) Expression in another window
Journal Articles

Vaults and drug resistance: What we learn from an MVP/LRP knockout mouse model.

Free
Erik A. Wiemer, Arend Van Zon, Marieke H. Mossink, George L. Scheffer, Rik J. Scheper, Pieter Sonneveld
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 568.
Published: 01 April 2004
View articletitled, Vaults and drug resistance: What we learn from an MVP/LRP knockout mouse model.
Journal Articles

In vitro priming of tumor-specific cytotoxic T lymphocytes from healthy donors using allogeneic dendritic cells derived from the MUTZ-3 cell line (NMDC)

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Saskia J. Santegoets, Marco W. Schreurs, Allan J. Masterson, Hans Baumeister, Steffen Goletz, Esther W. Kueter, Sinead M. Lougheed, Alfons J. Van Den Eerthwegh, Rik J. Scheper, Erik Hooijberg, Tanja D. De Gruijl
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 294.
Published: 01 April 2004
View articletitled, In vitro priming of tumor-specific cytotoxic T lymphocytes from healthy donors using allogeneic dendritic cells derived from the MUTZ-3 cell line (NMDC)
Journal Articles

Priming of cytotoxic T-lymphocytes against the novel tumor antigen ErbB3-binding protein-1 (Ebp-1)

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Tanja D. De Gruijl, Saskia J. Santegoets, Marco Schreurs, Marieke Van Ham, Erik Hooijberg, Alfons J. Van Den Eertwegh, Veerle A. Somers, Simon E. Hufton, Hennie R. Hoogenboom, Rik J. Scheper
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 292.
Published: 01 April 2004
View articletitled, Priming of cytotoxic T-lymphocytes against the novel tumor antigen ErbB3-binding protein-1 (Ebp-1)
Journal Articles

Multidrug resistance protein 4 (Mrp4) is expressed at the blood-cerebrospinal and blood-brain barriers and restricts topotecan brain penetration

Free
Markos Leggas, Masashi Adachi, Daxi Sun, Guoqing Du, Kelly E. Mercer, John C. Panetta, Yanli Zhuang, George L. Scheffer, Rik J. Scheper, Peter Wielinga, Piet Borst, Clinton F. Stewart, John D. Schuetz
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 115–116.
Published: 01 April 2004
View articletitled, Multidrug resistance protein 4 (Mrp4) is expressed at the blood-cerebrospinal and blood-brain barriers and restricts topotecan brain penetration