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Ricky A. Sharma
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Journal Articles

6-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance

Natalia Issaeva, Huw D. Thomas, Tatjana Djurenovic, Janneke E. Jaspers, Ivaylo Stoimenov, Suzanne Kyle, Nicholas Pedley, Ponnari Gottipati, Rafal Zur, Kate Sleeth, Vicky Chatzakos, Evan A. Mulligan, Cecilia Lundin, Evgenia Gubanova, Ariena Kersbergen, Adrian L. Harris, Ricky A. Sharma, Sven Rottenberg, Nicola J. Curtin, Thomas Helleday
Journal: Cancer Research
Cancer Res (2010) 70 (15): 6268–6276.
https://doi.org/10.1158/0008-5472.CAN-09-3416
Published: 28 July 2010
View article titled, 6-Thioguanine Selectively Kills BRCA2-Defective Tumors and Overcomes PARP Inhibitor Resistance
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Includes: Supplementary data
Journal Articles

Poly(ADP-Ribose) Polymerase Is Hyperactivated in Homologous Recombination–Defective Cells

Ponnari Gottipati, Barbara Vischioni, Niklas Schultz, Joyce Solomons, Helen E. Bryant, Tatjana Djureinovic, Natalia Issaeva, Kate Sleeth, Ricky A. Sharma, Thomas Helleday
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5389–5398.
https://doi.org/10.1158/0008-5472.CAN-09-4716
Published: 30 June 2010
View article titled, Poly(ADP-Ribose) Polymerase Is Hyperactivated in Homologous Recombination–Defective Cells
Open the PDF for Poly(ADP-Ribose) Polymerase Is Hyperactivated in Homologous Recombination–Defective Cells in another window
Journal Articles

Flutamide ameliorates oxidative DNA damage caused by dihydrotestosterone (DHT) in human prostate cancer cells

Sanjeev K. Pathak, Ricky A. Sharma, Raj Singh, Peter B. Farmer, William P. Steward, Andreas J. Gescher, Kilian Mellon
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 172.
Published: 01 April 2004
View article titled, Flutamide ameliorates oxidative DNA damage caused by dihydrotestosterone (DHT) in human prostate cancer cells