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Richard de Borja
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Journal Articles

Diverse Oncogenic Fusions and Distinct Gene Expression Patterns Define the Genomic Landscape of Pediatric Papillary Thyroid Carcinoma

Ana Stosic, Fabio Fuligni, Nathaniel D. Anderson, Scott Davidson, Richard de Borja, Meryl Acker, Vito Forte, Paolo Campisi, Evan J. Propst, Nikolaus E. Wolter, Rose Chami, Ozgur Mete, David Malkin, Adam Shlien, Jonathan D. Wasserman
Journal: Cancer Research
Cancer Res (2021) 81 (22): 5625–5637.
https://doi.org/10.1158/0008-5472.CAN-21-0761
Published: 15 November 2021
View article titled, Diverse Oncogenic Fusions and Distinct Gene Expression Patterns Define the Genomic Landscape of Pediatric Papillary Thyroid Carcinoma
Open the PDF for Diverse Oncogenic Fusions and Distinct Gene Expression Patterns Define the Genomic Landscape of Pediatric Papillary Thyroid Carcinoma in another window
Includes: Supplementary data
Journal Articles

Cancers from Novel Pole-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade

Melissa A. Galati, Karl P. Hodel, Miki S. Gams, Sumedha Sudhaman, Taylor Bridge, Walter J. Zahurancik, Nathan A. Ungerleider, Vivian S. Park, Ayse B. Ercan, Lazar Joksimovic, Iram Siddiqui, Robert Siddaway, Melissa Edwards, Richard de Borja, Dana Elshaer, Jiil Chung, Victoria J. Forster, Nuno M. Nunes, Melyssa Aronson, Xia Wang, Jagadeesh Ramdas, Andrea Seeley, Tomasz Sarosiek, Gavin P. Dunn, Jonathan N. Byrd, Oz Mordechai, Carol Durno, Alberto Martin, Adam Shlien, Eric Bouffet, Zucai Suo, James G. Jackson, Cynthia E. Hawkins, Cynthia J. Guidos, Zachary F. Pursell, Uri Tabori
Journal: Cancer Research
Cancer Res (2020) 80 (24): 5606–5618.
https://doi.org/10.1158/0008-5472.CAN-20-0624
Published: 15 December 2020
View article titled, Cancers from Novel <em>Pole</em>-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade
Open the PDF for Cancers from Novel <em>Pole</em>-Mutant Mouse Models Provide Insights into Polymerase-Mediated Hypermutagenesis and Immune Checkpoint Blockade in another window
Includes: Supplementary data
Journal Articles

Abstract 3666: The genomic landscape and clonal evolution of tumours arising in TP53 mutation carriers

Nicholas Light, Matthew Zatzman, Nathaniel Anderson, Vallijah Subasri, Mehdi Layeghifard, Ana Novokmet, James Tran, Richard de Borja, Fabio Fuligni, Joshua Schiffman, David Malkin, Adam Shlien
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3666.
https://doi.org/10.1158/1538-7445.AM2019-3666
Published: 01 July 2019
View article titled, Abstract 3666: The genomic landscape and clonal evolution of tumours arising in <em>TP53</em> mutation carriers
Journal Articles

Abstract 2506: Exploring the complex etiology of oncogenic fusions in childhood cancer

Nathaniel D. Anderson, Richard de Borja, Matthew D. Young, Fabio Fuligni, Andrej Rosic, Nicola D. Roberts, Nischalan Pillay, Jeffrey A. Toretsky, Yoshida Akihiko, Tatsuhiro Shibata, Markus Metzler, Gino Somers, Stephen W. Scherer, Adrienne M. Flanagan, Peter J. Campbell, Joshua D. Schiffman, Mary Shago, Ludmil B. Alexandrov, Jay S. Wunder, Irene L. Andrulis, David Malkin, Sam Behjati, Adam Shlien
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2506.
https://doi.org/10.1158/1538-7445.AM2019-2506
Published: 01 July 2019
View article titled, Abstract 2506: Exploring the complex etiology of oncogenic fusions in childhood cancer
Journal Articles

Abstract B09: DNA polymerase mutations trigger rapid onset of ultra-hypermutant malignant brain tumors in children with biallelic mismatch repair deficiency

Adam Shlien, Brittany B. Campbell, Richard de Borja, Ludmil B. Alexandrov, Daniele Merico, David Wedge, Peter Van Loo, Patrick S. Tarpey, Paul Coupland, Aaron Pollett, Tatiana Lipman, Abolfazl Heidari, Shriya Deshmukh, Moritz Gerstung, Diana Merino, Manasa Ramakrishna, Marc Remke, Roland Arnold, Gagan B. Panigrahi, Samina Afzal, Valerie Larouche, Harriet Druker, Jordan Lerner-Ellis, Matthew Mistry, Rina Dvir, Ronald Grant, Ronit Elhasid, Roula Farah, Glenn P. Taylor, Paul C. Nathan, Sarah Alexander, Shay Ben-Shachar, Nada Jabado, Steven Gallinger, Shlohmi Constantini, Peter Dirks, Annie Huang, Steven W. Scherer, Richard G. Grundy, Carol Durno, Melyssa Aronson, M Stephen Meyn, Michael D. Taylor, Zachary F. Pursell, Christopher E. Pearson, David Malkin, P Andrew Futreal, Cynthia Hawkins, Eric Bouffet, Michael D. Taylor, Peter J. Campbell, Uri Tabori
Journal: Cancer Research
Cancer Res (2015) 75 (23_Supplement): B09.
https://doi.org/10.1158/1538-7445.BRAIN15-B09
Published: 09 December 2015
View article titled, Abstract B09: DNA polymerase mutations trigger rapid onset of ultra-hypermutant malignant brain tumors in children with biallelic mismatch repair deficiency
Journal Articles

Abstract 2966: The mutational landscape of localized gleason 6 and 7 prostate cancer

Michael E. Fraser, Veronica Y. Sabelnykova, Takafumi N. Yamaguchi, Alice Meng, Lawrence E. Heisler, Junyan Zhang, Julie Livingstone, Vincent Huang, Andre P. Masella, Fouad Yousif, Michael Xie, Nicholas J. Harding, Xihui Lin, Haiying Kong, Stephenie D. Prokopec, Alejandro Berlin, Dominique Trudel, Xuemei Luo, Timothy E. Beck, Richard de Borja, Alister D'Costa, Robert E. Denroche, Natalie S. Fox, Emilie Lalonde, Ada Wong, Taryne Chong, Michelle Sam, Jeremy Johns, Lee Timms, Nicholas Buchner, Michele Orain, Valerie Picard, Helene Hovington, Kenneth C. Chu, Christine P'ng, Bryan Lo, Francis Nguyen, Kathleen E. Houlahan, Christopher Cooper, Shaylan K. Govind, Clement Fung, Louis Lacombe, Colin C. Collins, Yves Fradet, Bernard Tetu, Theodorus van der Kwast, John McPherson, Thomas J. Hudson, Rob G. Bristow, Paul Boutros
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2966.
https://doi.org/10.1158/1538-7445.AM2015-2966
Published: 01 August 2015
View article titled, Abstract 2966: The mutational landscape of localized gleason 6 and 7 prostate cancer
Journal Articles

Abstract B18: Genomic analysis of pancreatic ductal adenocarcinoma.

Christina K. Yung, Christine Ouellete, Lee Timms, Michelle Sam, Kimberly Begley, Thomas J. Hudson, John D. McPherson, Lincoln D. Stein, Timothy Beck, Lakshmi Muthuswamy, Richard De Borja, Carson Holt, Rob Denroche, Fouad Yousif, Zheng Zha, Niloofar Arshadi
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B18.
https://doi.org/10.1158/1538-7445.PANCA2012-B18
Published: 03 April 2014
View article titled, Abstract B18: Genomic analysis of pancreatic ductal adenocarcinoma.
Journal Articles

Abstract B13: Whole-genome mutation landscape in pancreatic ductal adenocarcinoma.

Carson Holt, Fouad Yousif, Lee Timms, Michelle Sam, Kimberly Begley, Thomas Hudson, John D. McPherson, Lincoln D. Stein, Lakshmi B. Muthuswamy, Christina Yung, Tim Beck, Bojan Losic, Niloofar Arshadi, Christine Ouelltt, Irinia Kalatskaya, Richard de Borja, Robert Denroche
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): B13.
https://doi.org/10.1158/1538-7445.PANCA2012-B13
Published: 03 April 2014
View article titled, Abstract B13: Whole-genome mutation landscape in pancreatic ductal adenocarcinoma.
Journal Articles

Abstract 5276: Normalization of miRNA-sequencing data.

Shirley Tam, Richard de Borja, Ming-Sound Tsao, John D. McPherson
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5276.
https://doi.org/10.1158/1538-7445.AM2013-5276
Published: 15 April 2013
View article titled, Abstract 5276: Normalization of miRNA-sequencing data.
Journal Articles

Abstract 2003: A molecular portrait of potentially curable prostate cancer.

Michael E. Fraser, Richard de Borja, Dominique Trudel, Nicholas J. Harding, Pablo H. Hennings-Yeomans, Alice Meng, Emilie R. Lalonde, Andrew Brown, Natalie S. Fox, Taryne Chong, Amin Zia, Michelle Sam, Jianxin Wang, Michelle A. Chan-Seng-Yue, Jeremy Johns, Lee Timms, Nicholas Buchner, Ada Wong, Fouad Yousif, Rob Denroche, Gaetano Zafarana, Maud HW Starmans, Hanbert Chen, Shaylan Govind, Francis Nguyen, Melania Pintilie, Neil Fleshner, Stanislav Volik, Lakshmi Muthuswamy, Colin C. Collins, Thomas J. Hudson, Lincoln D. Stein, Timothy Beck, John D. McPherson, Theodorus van der Kwast, Paul C. Boutros, Rob G. Bristow
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2003.
https://doi.org/10.1158/1538-7445.AM2013-2003
Published: 15 April 2013
View article titled, Abstract 2003: A molecular portrait of potentially curable prostate cancer.
Journal Articles

Abstract 3184: Whole genome sequencing of low-input fresh frozen prostate cancer biopsies

Michelle R. Sam, Taryne Chong, Amin Zia, Emilie Lalonde, Fouad Yousif, Rob Denroche, Michelle Chan-Seng-Yue, Alice Meng, Michael Fraser, Jeremy Johns, Lee Timms, Richard de Borja, Maud H.W. Starmans, Jianxin Wang, Pablo Hennings-Yeomans, Gaetano Zafarana, Melania Pintilie, Neil Fleshner, Lakshmi Muthuswamy, Colin Collins, Lincoln Stein, Thomas J. Hudson, Theodorus Van der Kwast, Timothy Beck, Paul Boutros, John D. McPherson, Robert G. Bristow
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 3184.
https://doi.org/10.1158/1538-7445.AM2012-3184
Published: 15 April 2012
View article titled, Abstract 3184: Whole genome sequencing of low-input fresh frozen prostate cancer biopsies