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Richard P. Bryce
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Journal Articles

Abstract PS4-13: Irreversible inhibition of HER2 activating mutations with neratinib enhances the pre-clinical efficacy of trastuzumab emtansine and trastuzumab deruxtecan

Ron Bose, Shunqiang Li, Tina M. Primeau, Maureen K. Highkin, Ashley R. Tipton, Nagalaxmi Vemalapally, Xuefeng Gao, Gail Sudlow, Irmina Diala, Yu Tao, Jingqin Luo, Ian Hagemann, Chieh-Yu Lin, Richard P. Bryce, Alshad S. Lalani, Samuel Achilefu, Cynthia X. Ma
Journal: Cancer Research
Cancer Res (2021) 81 (4_Supplement): PS4-13.
DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS4-13
Published: 15 February 2021
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Journal Articles

Abstract 929: Paired tumor and cfDNA in patients with HER2-mutant solid tumors treated with neratinib reveals convergence of multiple on-target resistance mechanisms: Results from the SUMMIT "Basket" Trial

Helen H. Won, S. Duygu Selcuklu, Sarina A. Piha-Paul, Cristina Saura, Jordi Rodon, Ingrid A. Mayer, Sherene Loi, Geoffrey I. Shapiro, Janice Lu, Adam Brufsky, Catherine Zimel, Myra Melcer, Maurizio Scaltriti, Lisa D. Eli, Richard E. Cutler, Jr., Alshad S. Lalani, Richard P. Bryce, Carlos Arteaga, Funda Meric-Bernstam, Michael F. Berger, David B. Solit, Alison Schram, David M. Hyman
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 929.
DOI: https://doi.org/10.1158/1538-7445.AM2019-929
Published: 01 July 2019
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Journal Articles

Abstract 3931: Neratinib-induced gene expression profile in breast cancer cells: A comprehensive transcriptome investigation

Yuxin Cui, Alwyn Dart, Richard E. Cutler, Alshad S. Lalani, Francesca Avogadri-Connors, Richard P. Bryce, Sioned Owen, Wen G. Jiang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3931.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3931
Published: 01 July 2018
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Journal Articles

Abstract 3995: Exploring non-small cell lung carcinoma cell lines' sensitivity to neratinib

Sioned Owen, Dafydd A. Dart, Alshad S. Lalani, Francesca Avogadri-Connors, Richard P. Bryce, Wen G. Jiang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3995.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3995
Published: 01 July 2018
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Journal Articles

Abstract 2894: Neratinib effects significant changes in human brain endothelial cells, demonstrating that it may have a therapeutic use in cancers with brain metastasis

Tracey A. Martin, Sioned Owen, Dafydd A. Dart, Francesca Avogadri Connors, Alshad S. Lalani, Richard P. Bryce, Wen G. Jiang
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2894.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2894
Published: 01 July 2018
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Journal Articles

Abstract 5244: Neratinib induced HER2 dependent and independent intracellular signaling events in human breast cancer cells and the clinical implications

W. G. Jiang, Tracey A. Martin, Sioned Owen, Ling Xin, Yinhua Liu, Fiona Ruge, Francesca Avogadri-Connors, Alshad S. Lalani, Richard P. Bryce, Eleri Davies
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5244.
DOI: https://doi.org/10.1158/1538-7445.AM2018-5244
Published: 01 July 2018
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Journal Articles

Abstract 879: Investigating the activity of neratinib in human gastric cancer and gastric cancer cells, implications on clinical outcome and chemotherapy resistance

W. G. Jiang, Tracey A. Martin, Sioned Owen, Lin Ye, Andrew J. Sanders, Yuxin Cui, Meng Xie, Shiqin Jia, Yongning Jia, Fiona Ruge, Francesca Avogadri-Connors, Alshad S. Lalani, Richard P. Bryce, Jiafu Ji
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 879.
DOI: https://doi.org/10.1158/1538-7445.AM2018-879
Published: 01 July 2018
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Journal Articles

Abstract CT001: Neratinib in HER2 or HER3 mutant solid tumors: SUMMIT, a global, multi-histology, open-label, phase 2 "basket" study

David M. Hyman, Sarina A. Piha-Paul, Jordi Rodon, Cristina Saura, Geoffrey I. Shapiro, David I. Quinn, Victor Moreno, Ingrid A. Mayer, Carlos Arteaga, Valentina Boni, Emiliano Calvo, Sherene Loi, Albert C. Lockhart, Lillian M. Smyth, Joseph Erinjeri, Maurizio Scaltriti, Gary Ulaner, Jean Torrisi, Juber Patel, Jiabin Tang, Fanli Meng, Duygu Selcuklu, Helen Won, Nancy Bouvier, Michael F. Berger, Richard E. Cutler, Feng Xu, Anna Butturini, Lisa D. Eli, Grace Mann, Alshad S. Lalani, Richard P. Bryce, Funda Meric-Bernstam, José Baselga, David B. Solit
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): CT001.
DOI: https://doi.org/10.1158/1538-7445.AM2017-CT001
Published: 01 July 2017
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