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Journal Articles

Abstract 2727: Elucidating genes that mediate brain colonization by metastatic melanoma cells

Denys Holovanchuk, Rebecca Lee, Alessio Cannistraci, Nathalie Dhomen, Valeria Pavet, Richard Marais
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2727.
https://doi.org/10.1158/1538-7445.AM2020-2727
Published: 15 August 2020
View article titled, Abstract 2727: Elucidating genes that mediate brain colonization by metastatic melanoma cells
Journal Articles

Abstract 3994: Genomic characterization of melanoma in the elderly reveals molecular drivers of progression and prognosis associated with immunotherapy response

Stephen P. Smith, Caroline Gaudy-Marqueste, Rajive Kumar, Richard Marais, Eduardo Nagore, Amaya Viros
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3994.
https://doi.org/10.1158/1538-7445.AM2019-3994
Published: 01 July 2019
View article titled, Abstract 3994: Genomic characterization of melanoma in the elderly reveals molecular drivers of progression and prognosis associated with immunotherapy response
Journal Articles

Abstract 4653: Melanocyte specific deletion of Map3k1 reveals its role in BRAFV600E-driven melanoma

Lucas D. Trucco, Piyushkumar A. Mundra, Pablo Garcia-Martinez, Kate Hogan, Nathalie Dhomen, Valeria Pavet, Richard Marais
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4653.
https://doi.org/10.1158/1538-7445.AM2019-4653
Published: 01 July 2019
View article titled, Abstract 4653: Melanocyte specific deletion of <em>Map3k1</em> reveals its role in BRAF<sup>V600E</sup>-driven melanoma
Journal Articles

Correction: In vitro Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors

Swee Y. Sharp, Kathy Boxall, Martin Rowlands, Chrisostomos Prodromou, S. Mark Roe, Alison Maloney, Marissa Powers, Paul A. Clarke, Gary Box, Sharon Sanderson, Lisa Patterson, Thomas P. Matthews, Kwai-Ming J. Cheung, Karen Ball, Angela Hayes, Florence Raynaud, Richard Marais, Laurence Pearl, Sue Eccles, Wynne Aherne, Edward McDonald, Paul Workman
Journal: Cancer Research
Cancer Res (2019) 79 (1): 287.
https://doi.org/10.1158/0008-5472.CAN-18-3578
Published: 02 January 2019
View article titled, Correction: <em>In vitro</em> Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors
Open the PDF for Correction: <em>In vitro</em> Biological Characterization of a Novel, Synthetic Diaryl Pyrazole Resorcinol Class of Heat Shock Protein 90 Inhibitors in another window
Journal Articles

Abstract 3438: Genetic analysis of melanoma from an albino patient

Candelaria Bracalente, Piyushkumar Mundra, Adriana Rinflerch, Pablo Garcia Martinez, Victoria Volonteri, Lucas Trucco, Gaston Galimberti, Nathalie Dhomen, Valeria Pavet Rodriguez, Richard Marais
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3438.
https://doi.org/10.1158/1538-7445.AM2018-3438
Published: 01 July 2018
View article titled, Abstract 3438: Genetic analysis of melanoma from an albino patient
Journal Articles

Abstract 5166: Lysyl oxidase regulates cell surface EGFR, and directionality of cancer cell invasion

Haoran Tang, Caroline Springer, Richard Marais
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5166.
https://doi.org/10.1158/1538-7445.AM2018-5166
Published: 01 July 2018
View article titled, Abstract 5166: Lysyl oxidase regulates cell surface EGFR, and directionality of cancer cell invasion
Journal Articles

Abstract IA18: Moving towards precision medicine for melanoma

Richard Marais
Journal: Cancer Research
Cancer Res (2017) 77 (22_Supplement): IA18.
https://doi.org/10.1158/1538-7445.NEWFRONT17-IA18
Published: 14 November 2017
View article titled, Abstract IA18: Moving towards precision medicine for melanoma
Journal Articles

Abstract 422: Lymph node metastasis evolution drives immune evasion and targeted therapy resistance in gastro-esophageal adenocarcinomas (GEAs)

Matthew N. Davies, Louise J. Barber, Georgia Spain, Filipa Lopes, Katharina von Loga, Beatrice Griffiths, Andrew Woolston, Donat Alpar, Marta Gomez, Kamil A. Lipinski, Kerry Fenwick, Zakaria Eltahir, Stefano Lise, Emese I. Agoston, Laszlo Harsanyi, Richard Marais, Andrew Wotherspoon, A Szasz, Caroline Springer, Marco Gerlinger
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 422.
https://doi.org/10.1158/1538-7445.AM2017-422
Published: 01 July 2017
View article titled, Abstract 422: Lymph node metastasis evolution drives immune evasion and targeted therapy resistance in gastro-esophageal adenocarcinomas (GEAs)
Journal Articles

Abstract 1561: Gene expression analysis identifies heterogeneity in cutaneous melanoma subjects with disruptive MC1R alleles and BRAF hotspot mutations

Piyushkumar A. Mundra, Candelaria Bracalente, Lucas Trucco, Nathalie Dhomen, Richard Marais
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1561.
https://doi.org/10.1158/1538-7445.AM2017-1561
Published: 01 July 2017
View article titled, Abstract 1561: Gene expression analysis identifies heterogeneity in cutaneous melanoma subjects with disruptive <em>MC1R</em> alleles and <em>BRAF</em> hotspot mutations
Journal Articles

Abstract 905: Lysyl oxidase is required for chemotaxis

Haoran Tang, Nathalie Dhomen, Richard Marais
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 905.
https://doi.org/10.1158/1538-7445.AM2017-905
Published: 01 July 2017
View article titled, Abstract 905: Lysyl oxidase is required for chemotaxis
Journal Articles

Abstract 5685: An evaluation of DNA and RNA based blood biomarkers in prostate cancer

Jenny Antonello, Jakub Chudziak, Alan Redfern, Victoria Foy, Shambhavi Srivastava, Adnan Syed, Deborah Burt, Mahmood Ayub, Bedirhan Kilerci, Marina Parry, Richard Marais, Esther Baena, Crispin Miller, Dominic Rothwell, Noel Clarke, Caroline Dive, Ged Brady
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5685.
https://doi.org/10.1158/1538-7445.AM2017-5685
Published: 01 July 2017
View article titled, Abstract 5685: An evaluation of DNA and RNA based blood biomarkers in prostate cancer
Journal Articles

Abstract 3393: Genomic analysis of multi-site fresh prostate samples

Marina A. Parry, Shambhavi Srivastava, Alessio Cannistraci, Hui Sun Leong, Syed Ali, Jenny Antonello, Vijay Ramani, Maurice Lau, Jonathan Shanks, Daisuke Nonaka, Pedro Oliveira, Noel Clarke, Crispin Miller, Ged Brady, Nathalie Dhomen, Esther Baena, Richard Marais
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 3393.
https://doi.org/10.1158/1538-7445.AM2017-3393
Published: 01 July 2017
View article titled, Abstract 3393: Genomic analysis of multi-site fresh prostate samples
Journal Articles

Abstract 4844: CRISPR-generated BAP1 knockdown in uveal melanoma cell lines affects organotropism

Katharina Mahal, Kelly Brooks, Amit Mandal, Matthew Smith, Nathalie Dhomen, Richard Marais
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4844.
https://doi.org/10.1158/1538-7445.AM2017-4844
Published: 01 July 2017
View article titled, Abstract 4844: CRISPR-generated BAP1 knockdown in uveal melanoma cell lines affects organotropism
Journal Articles

Abstract LB-212: Therapeutic efficacy of the paradox-breaking panRAF and SRC drug CCT3833/BAL3833 in KRAS-driven cancer models

Grazia Saturno, Filipa Lopes, Maria Romina Girotti, Ion Niculescu-Duvaz, Dan Niculescu-Duvaz, Alfonso Zambon, Lawrence Davies, Louise Johnson, Natasha Preece, Amaya Viros, Malin Pedersen, Robert McLeary, Ruth Knight, Rebecca Lee, Denys Holovanchuk, Paul Lorigan, Nathalie Dhomen, Richard Marais, Caroline Springer
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-212.
https://doi.org/10.1158/1538-7445.AM2016-LB-212
Published: 15 July 2016
View article titled, Abstract LB-212: Therapeutic efficacy of the paradox-breaking panRAF and SRC drug CCT3833/BAL3833 in KRAS-driven cancer models
Journal Articles

Abstract PL04-04: Developing circulating tumor cell derived explant models (CDX)

Caroline Dive, Kris Frese, Melanie Galvin, Alice Lallo, Cassandra Hodgkinson, Christopher Morrow, Kathryn Simpson, Francesca Trappani, Stuart Williamson, Lynsey Priest, Romina Girotti, Crispin Miller, Ged Brady, Richard Marais, Fiona Blackhall
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): PL04-04.
https://doi.org/10.1158/1538-7445.AM2016-PL04-04
Published: 15 July 2016
View article titled, Abstract PL04-04: Developing circulating tumor cell derived explant models (CDX)
Journal Articles

Abstract 3207: Influence of tumor mutation burden on response to anti-PD-1 treatment in murine models of melanoma

Elena Galvani, Kate Hogan, Gabriela Gremel, Amaya Viros, Amit K. Mandal, Matthew Smith, Jacqueline Swan, Antonia Banyard, Garry Ashton, Nathalie Dhomen, Richard Marais
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3207.
https://doi.org/10.1158/1538-7445.AM2016-3207
Published: 15 July 2016
View article titled, Abstract 3207: Influence of tumor mutation burden on response to anti-PD-1 treatment in murine models of melanoma
Journal Articles

Abstract 4167: Ultraviolet radiation cooperates with individual oncogenes to drive melanomagenesis through distinct molecular mechanisms

Amaya Viros, Malin Pedersen, Simon J. Furney, Maria Romina Girotti, Grazia Saturno, Elena Galvani, Berta Sanchez-Laorden, Kate Hogan, Charlotte Ng, Jorge S. Reis-Filho, Paul Lorigan, Martin Cook, Richard Marais
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4167.
https://doi.org/10.1158/1538-7445.AM2016-4167
Published: 15 July 2016
View article titled, Abstract 4167: Ultraviolet radiation cooperates with individual oncogenes to drive melanomagenesis through distinct molecular mechanisms
Journal Articles

Abstract 2400: Mechanisms of resistance to immuno and targeted therapies in acral melanoma

Rebecca J. Lee, Maria Romina Girotti, Amaya Viros, Franziska Baenke, Amit Mandal, Garima Khandelwal, John Bridgeman, Elena Galvani, Gabriela Gremel, Milena Kalaitsidou, Garry Ashton, Isabel Peset, Matthew Smith, Jacqueline Swan, Kang Zeng, Haoran Tang, Caron Abbey, Robert Hawkins, Alberto Fusi, Crispin Miller, David Gilham, Nathalie Dhomen, Paul Lorigan, Richard Marais
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2400.
https://doi.org/10.1158/1538-7445.AM2016-2400
Published: 15 July 2016
View article titled, Abstract 2400: Mechanisms of resistance to immuno and targeted therapies in acral melanoma
Journal Articles

Abstract 469: Systematic analysis of circulating tumor DNA in melanoma patients to uncover mechanisms of resistance and disease clonality

Gabriela Gremel, Rebecca J. Lee, Maria R. Girotti, Grace Garner, Amit K. Mandal, Sally Wood, Alberto Fusi, Sara Valpione, Patricio Serra-Bellver, Nathalie Dhomen, Paul Lorigan, Richard Marais
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 469.
https://doi.org/10.1158/1538-7445.AM2016-469
Published: 15 July 2016
View article titled, Abstract 469: Systematic analysis of circulating tumor DNA in melanoma patients to uncover mechanisms of resistance and disease clonality
Journal Articles

Abstract 470: Application of sequencing, liquid biopsies and patient derived xenografts for personalized medicine in melanoma

Maria R. Girotti, Gabriela Gremel, Rebecca Lee, Elena Galvani, Dominic Rothwell, Amaya Viros, Amit Kumar Mandal, Kok Haw Jonathan Lim, Grazia Saturno, Simon J Furney, Franziska Baenke, Malin Pedersen, Jane Rogan, Jacqueline Swan, Matthew Smith, Alberto Fusi, Deemesh Oudit, Nathalie Dhomen, Ged Brady, Caroline Dive, Richard Marais
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 470.
https://doi.org/10.1158/1538-7445.AM2016-470
Published: 15 July 2016
View article titled, Abstract 470: Application of sequencing, liquid biopsies and patient derived xenografts for personalized medicine in melanoma