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Richard Koche
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Journal Articles

Abstract 5583: SUV39H1 disruption enhances the persistence and anti-tumor efficacy of CD28-costimulated human CAR T cells

Nayan Jain, Zeguo Zhao, Richard Koche, Yosi Gozlan, David Brocks, Tali Raveh-Sadka, Danny Wells, Anton Dobrin, Yuzhe Shi, Michael Lopez, Gertrude Gunset, Michel Sadelain
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5583.
DOI: https://doi.org/10.1158/1538-7445.AM2022-5583
Published: 15 June 2022
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Journal Articles

Abstract LB153: Emergence of a hyper-proliferative phenotype in TET2 edited human CAR T cells

Nayan Jain, Zeguo Zhao, Archana Iyer, Michael Lopez, Judith Feucht, Richard Koche, Julie Yang, Yingqian Zhan, Michel Sadelain
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): LB153.
DOI: https://doi.org/10.1158/1538-7445.AM2021-LB153
Published: 01 July 2021
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Journal Articles

Abstract 3439: FOXA1 mutations reveal distinct chromatin profiles and influence therapeutic response in breast cancer

Amaia Arruabarrena-Aristorena, Jesper LV Maag, Srushti Kittane, Yanyan Cai, Jane Park, Pedram Razavi, Lorenzo Ferrando, Pier Selenica, Wouter R. Karthaus, Srinivasaraghavan Kannan, Emiliano Cocco, Sik Y. Ho, Daisylyn Senna Tan, Mirna Sallaku, Charles L. Sawyers, Jorge S. Reis-Fihlo, Chandra S. Verma, Ralf Jauch, Richard Koche, José Baselga, Eneda Toska, Maurizio Scaltriti
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3439.
DOI: https://doi.org/10.1158/1538-7445.AM2020-3439
Published: 15 August 2020
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Journal Articles

Abstract A12: L1CAM defines the regenerative origin of metastasis initiating cells in colorectal cancer

Karuna Ganesh, Harihar Basnet, Yasemin Kaygusuz, Ashley Laughney, Lan He, Roshan Sharma, Kevin O'Rourke, Vincent Reuter, Yun-Han Huang, Ignas Masilionis, Mesruh Turkekul, Ekrem Er, Katja Manova-Todorova, Leonard Saltz, Martin Weiser, Julio Garcia-Aguilar, Richard Koche, Scott Lowe, Dana Peer, Jinru Shia, Joan Massague
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): A12.
DOI: https://doi.org/10.1158/1538-7445.CAMODELS2020-A12
Published: 02 June 2020
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Journal Articles

Abstract A05: Chromatin dynamics in vivo reveal a complex cell fate transition and master regulators of the development of pancreatic intraepithelial neoplasia

Rohit Chandwani, Alexa Osterhoudt, Richard Koche, Steven D. Leach
Journal: Cancer Research
Cancer Res (2019) 79 (24_Supplement): A05.
DOI: https://doi.org/10.1158/1538-7445.PANCA19-A05
Published: 13 December 2019
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Journal Articles

Abstract 4888: Human PGBD5 DNA transposase promotes site-specific oncogenic mutations in rhabdoid tumors

Anton G. Henssen, Richard Koche, Jiali Zhuang, Eileen Jiang, Casie Reed, Amy Eisenberg, Eric Still, Elias Rodríguez-Fos, Santiago Gonzalez, Montserrat Puiggròs, Andrew N. Blackford, Christopher E. Mason, Elisa de Stanchina, Mithat Gönen, Anne-Katrin Emde, Minita Shah, Kanika Arora, Catherine Reeves, Nicholas D. Socci, Elizabeth Perlman, Cristina R. Antonescu, Charles W. Roberts, Hanno Steen, Elizabeth Mullen, Stephen P. Jackson, David Torrents, Zhiping Weng, Scott A. Armstrong, Alex Kentsis
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4888.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4888
Published: 01 July 2017
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Journal Articles

Abstract 1103: Human tumorigenesis induced by endogenous DNA transposase

Anton Henssen, Amy Eisenberg, Eileen Jiang, Elizabeth Henaff, Richard Koche, Melissa Burns, Julianne R. Carson, Gouri Nanjangud, Eric Still, Jorge Gandara, Paolo Cifani, Avantika Dhabaria, Xiaodong Huang, Elisa de Stanchina, Elizabeth Mullen, Hanno Steen, Elizabeth Perlman, Jeffrey Dome, Cristina Antonescu, Cedric Feschotte, Christopher E. Mason, Alex Kentsis
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1103.
DOI: https://doi.org/10.1158/1538-7445.AM2015-1103
Published: 01 August 2015
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Journal Articles

Abstract 4731: Targeting super-enhancer induced gene expression with the novel BRD4 inhibitor OTX015 in preclinical models of MYCN-amplified neuroblastoma

Anton Henssen, Kristina Althoff, Richard Koche, Andrea Odersky, Anneleen Beckers, Frank Speleman, Simon Schäfers, Katleen De Preter, Alexandra Florin, Lukas Heukamp, Annika Spruessel, Kathy Astrahanseff, Natalie Sadowski, Alexander Schramm, Angelika Eggert, Lucile Astorgues-Xerri, Eugenia Riveiro, Esteban Cvitkovic, Johannes H. Schulte
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4731.
DOI: https://doi.org/10.1158/1538-7445.AM2015-4731
Published: 01 August 2015
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