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Abstract LB-186: Sustained efficacy of immunotherapy for solid tumors with novel dual CD4/CD8 T cell receptor engineered synergistic combination of hematopoietic stem cells and T cells

Richard C. Koya, Thinle Chodon, Junko Matsuzaki, Takemasa Tsuji, Satoko Matsueda, Kunle Odunsi

Cancer Res (2017) 77 (13_Supplement): LB-186.

DOI: https://doi.org/10.1158/1538-7445.AM2017-LB-186

Published: 01 July 2017

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Journal Articles

Abstract A65: Improved immunological responses against melanoma in vivo with T lymphocyte adoptive cell therapy coupled with targeted inhibition of mutated and activated BRAF

Richard C. Koya, Stephen Mok, Nicholas Otte, Thinle Chodon, Begonya Comin-Anduix, Antoni Ribas

Cancer Res (2011) 71 (18_Supplement): A65.

DOI: https://doi.org/10.1158/1538-7445.FBCR11-A65

Published: 28 October 2014

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Journal Articles

Abstract 5015: TCR usage analysis in blood reveals different mechanisms of action of CTLA-4 and PD-1 blockade in patients

Lidia Robert, Christina L. Harview, Ryan Emerson, Stephen Mok, Blanca Homet, Begonya Comin-Anduix, Richard C. Koya, Harlan Robins, Paul C. Tumeh, Antoni Ribas

Cancer Res (2014) 74 (19_Supplement): 5015.

DOI: https://doi.org/10.1158/1538-7445.AM2014-5015

Published: 01 October 2014

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Journal Articles

HSV-sr39TK Positron Emission Tomography and Suicide Gene Elimination of Human Hematopoietic Stem Cells and Their Progeny in Humanized Mice

Eric H. Gschweng, Melissa N. McCracken, Michael L. Kaufman, Michelle Ho, Roger P. Hollis, Xiaoyan Wang, Navdeep Saini, Richard C. Koya, Thinle Chodon, Antoni Ribas, Owen N. Witte, Donald B. Kohn

Cancer Res (2014) 74 (18): 5173–5183.

DOI: https://doi.org/10.1158/0008-5472.CAN-14-0376

Published: 14 September 2014

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Includes: Multimedia, Supplementary data

Journal Articles

Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy

Stephen Mok, Richard C. Koya, Christopher Tsui, Jingying Xu, Lídia Robert, Lily Wu, Thomas G. Graeber, Brian L. West, Gideon Bollag, Antoni Ribas

Cancer Res (2014) 74 (1): 153–161.

DOI: https://doi.org/10.1158/0008-5472.CAN-13-1816

Published: 05 January 2014

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Includes: Supplementary data

Journal Articles

Abstract 3969: Blocking colony stimulating factor 1 receptor (CSF1R) improves anti-tumor effects of adoptive T cell transfer therapy.

Stephen Mok, Christopher Tsui, Jingying Xu, Begonya Comin-Anduix, Thinle Chodon, Antoni Ribas, Richard C. Koya

Cancer Res (2013) 73 (8_Supplement): 3969.

DOI: https://doi.org/10.1158/1538-7445.AM2013-3969

Published: 15 April 2013

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Journal Articles

BRAF Inhibitor Vemurafenib Improves the Antitumor Activity of Adoptive Cell Immunotherapy

Richard C. Koya, Stephen Mok, Nicholas Otte, Kevin J. Blacketor, Begonya Comin-Anduix, Paul C. Tumeh, Aspram Minasyan, Nicholas A. Graham, Thomas G. Graeber, Thinle Chodon, Antoni Ribas

Cancer Res (2012) 72 (16): 3928–3937.

DOI: https://doi.org/10.1158/0008-5472.CAN-11-2837

Published: 14 August 2012

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Includes: Supplementary data

Journal Articles

Abstract 1563: In vivo safety and efficacy of a novel dendritic cell based Ad-GMCAIX vaccine with activity against renal cell carcinoma

Frédéric D. Birkhäuser, Richard C. Koya, Caleb Neufeld, Xuyang Lu, Ewa D. Micewicz, Thinle Chodon, Mohammad Atefi, Nils Kroeger, Edward N. Rampersaud, Gadisetti VR Chandramouli, Gang Li, Jonathan W. Said, Antoni Ribas, William H. McBride, Fairooz F. Kabbinavar, Allan J. Pantuck, Arie S. Belldegrun, Joseph Riss

Cancer Res (2012) 72 (8_Supplement): 1563.

DOI: https://doi.org/10.1158/1538-7445.AM2012-1563

Published: 15 April 2012

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Journal Articles

Abstract 836: Insulin-like growth factor-I receptor (IGF-IR) dowregulation in cisplatin-resistant human ovarian cancer cells

Chintda Santiskulvong, Carol Eng, David T. Wang, Wing Y. Lung, Sara Zabih, Richard C. Koya, Oliver Dorigo

Cancer Res (2012) 72 (8_Supplement): 836.

DOI: https://doi.org/10.1158/1538-7445.AM2012-836

Published: 15 April 2012

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Journal Articles

Abstract 3510: Paradoxical MAPK activation and beneficial effects of vemurafenib on T-cell phenotype resulting in improved functionality in vivo

Richard C. Koya, Stephen Mok, Nicholas Otte, Thinle Chodon, Begonya Comin-Anduix, Kevin Blacketor, Paul C. Tumeh, Antoni Ribas

Cancer Res (2012) 72 (8_Supplement): 3510.

DOI: https://doi.org/10.1158/1538-7445.AM2012-3510

Published: 15 April 2012

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Journal Articles

Abstract 4713: Detrimental effects of a histone deacetylase inhibitor on human lymphocytes

Deborah L. Wong, Amol -. Rao, Earl -. Avramis, Douglas R. Matsunaga, Kimberly M. Komatsubara, Tinle -. Chodon, Richard C. Koya, Ribas -. Antoni, Begonya -. Comin-Anduix

Cancer Res (2012) 72 (8_Supplement): 4713.

DOI: https://doi.org/10.1158/1538-7445.AM2012-4713

Published: 15 April 2012

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Journal Articles

Abstract SY03-04: Novel imaging approaches for immunotherapy and targeted therapy of melanoma in animal models and humans

Antoni Ribas, Thinle Chodon, Begonya Comin-Anduix, Jonas Sondergaard, Stephen Mok, Charles Ng, Helena Escuin-Ordinas, Mohammad Atefi, Bartosz Chmielowski, Johannes Czernin, Owen N. Witte, Caius G. Radu, Richard C. Koya

Cancer Res (2011) 71 (8_Supplement): SY03-04.

DOI: https://doi.org/10.1158/1538-7445.AM2011-SY03-04

Published: 15 April 2011

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Journal Articles

Abstract 5518: Characterization of invariant natural killer T cells in patients with advanced melanoma treated with CTLA4 blockade and dendritic cell vaccination

Javier -. Ibarrondo, Begoña -. Comin-Anduix, Yohan -. Lee, Thinle -. Chodon, Hooman -. Sazegar, Jason -. Jalil, Bartosz -. Chmielowski, Richard C. Koya, Jesus -. Gomez-Navarro, Beth D. Jamieson, Antoni -. Ribas

Cancer Res (2011) 71 (8_Supplement): 5518.

DOI: https://doi.org/10.1158/1538-7445.AM2011-5518

Published: 15 April 2011

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Journal Articles

Abstract 656: Antitumor activity of combined therapy with the class I BRAF inhibitor PLX4032 and immunotherapy

Richard C. Koya, Stephen Mok, Nicholas Otte, Begonya Comin-Anduix, Thinle Chodon, Antoni Ribas

Cancer Res (2011) 71 (8_Supplement): 656.

DOI: https://doi.org/10.1158/1538-7445.AM2011-656

Published: 15 April 2011

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Journal Articles

Molecular Mechanism of MART-1⁺/A*0201⁺ Human Melanoma Resistance to Specific CTL-Killing Despite Functional Tumor–CTL Interaction

Ali R. Jazirehi, Stavroula Baritaki, Richard C. Koya, Benjamin Bonavida, James S. Economou

Cancer Res (2011) 71 (4): 1406–1417.

DOI: https://doi.org/10.1158/0008-5472.CAN-10-1296

Published: 14 February 2011

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Includes: Supplementary data

Journal Articles

Abstract 1937: Enhanced tumor control with adoptive transfer of TCR engineered T cells expressing Tcl1

Richard C. Koya, Stephen Mok, Thinle Chodon, Michael Teitell, Antoni Ribas

Cancer Res (2010) 70 (8_Supplement): 1937.

DOI: https://doi.org/10.1158/1538-7445.AM10-1937

Published: 15 April 2010

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Journal Articles

Alloreactive cytotoxic T lymphocytes engineered as RCR vector producer cells for cellular delivery: Combined cellular and gene therapy for gliomas

Kazunori Haga, German G. Gomez, Christopher R. Logg, Takahiro Kimura, Kei Hiraoka, Richard C. Koya, Carol A. Kruse, Noriyuki Kasahara

Cancer Res (2006) 66 (8_Supplement): 495.

Published: 15 April 2006

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Journal Articles

Transcriptional targeting and pseudotyping of RCR vectors improves the selectivity and efficiency of viral replication and tumor transduction in prostate cancer models

Takahiro Kimura, Christopher R. Logg, Kei Hiraoka, Kazunori Haga, Richard C. Koya, Bernard H. Bochner, Robert J. Matusik, Renata Stripecke, Noriyuki Kasahara

Cancer Res (2006) 66 (8_Supplement): 946.

Published: 15 April 2006

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Journal Articles

Immunostimulatory efficiency of dendritic cells generated by lentiviral transduction of cytokines against melanoma

Richard C. Koya, Noriyuki Kasahara, Takahiro Kimura, Antoni Ribas, Renata Stripecke

Cancer Res (2005) 65 (9_Supplement): 998–999.

Published: 01 May 2005

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NARROW

Abstract LB-186: Sustained efficacy of immunotherapy for solid tumors with novel dual CD4/CD8 T cell receptor engineered synergistic combination of hematopoietic stem cells and T cells

Abstract A65: Improved immunological responses against melanoma in vivo with T lymphocyte adoptive cell therapy coupled with targeted inhibition of mutated and activated BRAF

Abstract 5015: TCR usage analysis in blood reveals different mechanisms of action of CTLA-4 and PD-1 blockade in patients

HSV-sr39TK Positron Emission Tomography and Suicide Gene Elimination of Human Hematopoietic Stem Cells and Their Progeny in Humanized Mice

Inhibition of CSF-1 Receptor Improves the Antitumor Efficacy of Adoptive Cell Transfer Immunotherapy

Abstract 3969: Blocking colony stimulating factor 1 receptor (CSF1R) improves anti-tumor effects of adoptive T cell transfer therapy.

BRAF Inhibitor Vemurafenib Improves the Antitumor Activity of Adoptive Cell Immunotherapy

Abstract 1563: In vivo safety and efficacy of a novel dendritic cell based Ad-GMCAIX vaccine with activity against renal cell carcinoma

Abstract 836: Insulin-like growth factor-I receptor (IGF-IR) dowregulation in cisplatin-resistant human ovarian cancer cells

Abstract 3510: Paradoxical MAPK activation and beneficial effects of vemurafenib on T-cell phenotype resulting in improved functionality in vivo

Abstract 4713: Detrimental effects of a histone deacetylase inhibitor on human lymphocytes

Abstract SY03-04: Novel imaging approaches for immunotherapy and targeted therapy of melanoma in animal models and humans

Abstract 5518: Characterization of invariant natural killer T cells in patients with advanced melanoma treated with CTLA4 blockade and dendritic cell vaccination

Abstract 656: Antitumor activity of combined therapy with the class I BRAF inhibitor PLX4032 and immunotherapy

Molecular Mechanism of MART-1⁺/A*0201⁺ Human Melanoma Resistance to Specific CTL-Killing Despite Functional Tumor–CTL Interaction

Abstract 1937: Enhanced tumor control with adoptive transfer of TCR engineered T cells expressing Tcl1

Alloreactive cytotoxic T lymphocytes engineered as RCR vector producer cells for cellular delivery: Combined cellular and gene therapy for gliomas

Transcriptional targeting and pseudotyping of RCR vectors improves the selectivity and efficiency of viral replication and tumor transduction in prostate cancer models

Immunostimulatory efficiency of dendritic cells generated by lentiviral transduction of cytokines against melanoma

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