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Journal Articles

Abstract PS5-02: Assessment of early ctDNA dynamics to predict efficacy of targeted therapies in metastatic breast cancer: Results from plasmaMATCH trial

Cancer Res (2021) 81 (4_Supplement): PS5-02.

DOI: https://doi.org/10.1158/1538-7445.SABCS20-PS5-02

Published: 15 February 2021

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Journal Articles

Abstract 734: Monitoring of dynamic changes and clonal evolution in circulating tumor DNA from patients with IDH-mutated cholangiocarcinoma treated with IDH inhibitors

Morten Lapin, Helen J. Huang, Milind Javle, Rachna T. Shroff, Shubham Pant, Anjali Raina, Kiran Madwani, Veronica R. Holley, S. Greg Call, Richard B. Lanman, Lawrence Kwong, Funda Meric-Bernstam, Victoria M. Raymond, Filip Janku

Cancer Res (2020) 80 (16_Supplement): 734.

DOI: https://doi.org/10.1158/1538-7445.AM2020-734

Published: 15 August 2020

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Journal Articles

Abstract P4-10-15: PIK3CA mutational analysis using cell-free DNA next-generation sequencing detects activating mutations that may be missed with targeted hot-spot testing

Lesli A Kiedrowski, Dejan Juric, Aaron I Hardin, Kristin S Price, Rebecca J Nagy, Carlos L Arteaga, Joyce O'Shaughnessy, Aditya Bardia, Massimo Cristofanilli, Richard B Lanman

Cancer Res (2020) 80 (4_Supplement): P4-10-15.

DOI: https://doi.org/10.1158/1538-7445.SABCS19-P4-10-15

Published: 15 February 2020

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Journal Articles

Abstract P5-01-06: Cell-free DNA (cfDNA) analysis of ESR1-mutant advanced breast cancer (aBC): Impact of subsequent therapy on mutation persistence

Caroline M. Weipert, Thereasa A. Rich, Rebecca J. Nagy, Sarah Croessmann, Ben H. Park, Joyce O'Shaughnessy, Mohammad Nezami, Massimo Cristofanilli, Aditya Bardia, Richard B. Lanman

Cancer Res (2020) 80 (4_Supplement): P5-01-06.

DOI: https://doi.org/10.1158/1538-7445.SABCS19-P5-01-06

Published: 15 February 2020

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Journal Articles

Abstract LB-118: Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation

Cancer Res (2019) 79 (13_Supplement): LB-118.

DOI: https://doi.org/10.1158/1538-7445.AM2019-LB-118

Published: 01 July 2019

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Journal Articles

Abstract 2509: Analysis of clonal hematopoiesis-associated mutations in the cell-free DNA of advanced cancer patients

Jennifer Yen, Katie Quinn, Elena Helman, Andrey Chursov, Tracy Nance, Ariel Jaimovich, Kimberly Banks, Aleksandra Franovic, Kristin Gleitsman, John Latham, Arielle Yablonovitch, Marcin Sikora, Stephen Fairclough, Darya Chudova, Richard B. Lanman, AmirAli Talasaz

Cancer Res (2019) 79 (13_Supplement): 2509.

DOI: https://doi.org/10.1158/1538-7445.AM2019-2509

Published: 01 July 2019

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Journal Articles

Abstract 435: Cell-free circulating tumor DNA (ctDNA) detects somatic copy number loss in homologous recombination repair genes

Catalin Barbacioru, Victoria M. Raymond, Marcin Sikora, Elena Helman, Sante Gnerre, Stephen Fairclough, Darya Chudova, Richard B. Lanman, AmirAli Talasaz

Cancer Res (2019) 79 (13_Supplement): 435.

DOI: https://doi.org/10.1158/1538-7445.AM2019-435

Published: 01 July 2019

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Journal Articles

Abstract 450: Novel genomic differences in cell-free circulating tumor DNA (cfDNA) profiles of early versus older onset colorectal cancer (CRC)

Afsaneh Barzi, Carin R. Espenschied, Victoria M. Raymond, Richard B. Lanman, Heinz-Josef Lenz

Cancer Res (2019) 79 (13_Supplement): 450.

DOI: https://doi.org/10.1158/1538-7445.AM2019-450

Published: 01 July 2019

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Journal Articles

Abstract 3404: Landscape and genomic correlates of ctDNA-based tumor mutational burden across six solid tumor types

Katie Quinn, Elena Helman, Tracy Nance, Jennifer Yen, John Latham, Kristin Gleitsman, Ravi Vijaya-Satya, Carlo Artieri, Alex Artyomenko, Marcin Sikora, Darya Chudova, Richard B. Lanman, AmirAli Talasaz

Cancer Res (2019) 79 (13_Supplement): 3404.

DOI: https://doi.org/10.1158/1538-7445.AM2019-3404

Published: 01 July 2019

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Journal Articles

Abstract 936: Analysis of cell-free DNA from 32,991 advanced cancers reveals novel co-occurring activating RET alterations and oncogenic signaling pathway aberrations

Karen L. Reckamp, Thereasa A. Rich, Young Kwang Chae, Robert C. Doebele, Wade T. Iams, Michael Oh, Victoria M. Raymond, Richard B. Lanman, Thomas E. Stinchcombe, Vivek Subbiah, David R. Trevarthen, Oliver P. Gautschi

Cancer Res (2018) 78 (13_Supplement): 936.

DOI: https://doi.org/10.1158/1538-7445.AM2018-936

Published: 01 July 2018

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Journal Articles

Abstract 5533: Cell-free DNA sequencing in ERBB2-mutant breast cancer patients treated with neratinib and fulvestrant: Exploratory analysis from the Phase 2 SUMMIT ‘basket' trial

Alison M. Schram, S. Duygu Selcuklu, Rebecca J. Nagy, Lillian M. Smyth, Lisa D. Eli, Richard E. Cutler, Alshad S. Lalani, David M. Hyman, Richard B. Lanman

Cancer Res (2018) 78 (13_Supplement): 5533.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5533

Published: 01 July 2018

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Journal Articles

Abstract 5603: Analytical validation of a comprehensive 500-gene ctDNA panel designed for immuno-oncology and DNA damage research

Elena Helman, Carlo Artieri, James V. Vowles, Jennifer Yen, Tracy Nance, Marcin Sikora, Joshua Gourneau, Mohit Goel, Stefanie Mortimer, Darya Chudova, Justin Odegaard, Richard B. Lanman, AmirAli Talasaz

Cancer Res (2018) 78 (13_Supplement): 5603.

DOI: https://doi.org/10.1158/1538-7445.AM2018-5603

Published: 01 July 2018

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Journal Articles

Abstract 4272: A novel approach to differentiation of somatic vs. germline variants in liquid biopsies using a betabinomial model

Tracy Nance, Elena Helman, Carlo Artieri, Jennifer Yen, Thomas P. Slavin, Darya Chudova, Richard B. Lanman, AmirAli Talasaz

Cancer Res (2018) 78 (13_Supplement): 4272.

DOI: https://doi.org/10.1158/1538-7445.AM2018-4272

Published: 01 July 2018

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Journal Articles

Abstract 3662: Cell-free DNA sequencing demonstrates persistence of nucleic acid-based therapy—opportunities for detection and monitoring

Marcin Sikora, Alexander Artyomenko, James Strauss, Richard B. Lanman, Victoria M. Raymond, Justin Odegaard

Cancer Res (2018) 78 (13_Supplement): 3662.

DOI: https://doi.org/10.1158/1538-7445.AM2018-3662

Published: 01 July 2018

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Journal Articles

Abstract 2190: A method for differentiating clonal driver mutations from subclonal emerging resistance mutations in circulating cell-free DNA

Stephen Fairclough, Oliver Zill, Catalin Barbacioru, Justin Odegaard, Richard B. Lanman, AmirAli Talasaz, Darya Chudova

Cancer Res (2018) 78 (13_Supplement): 2190.

DOI: https://doi.org/10.1158/1538-7445.AM2018-2190

Published: 01 July 2018

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Journal Articles

Genomic Alterations in Circulating Tumor DNA from Diverse Cancer Patients Identified by Next-Generation Sequencing

Maria Schwaederle, Ranajoy Chattopadhyay, Shumei Kato, Paul T. Fanta, Kimberly C. Banks, In Sil Choi, David E. Piccioni, Sadakatsu Ikeda, AmirAli Talasaz, Richard B. Lanman, Lyudmila Bazhenova, Razelle Kurzrock

Cancer Res (2017) 77 (19): 5419–5427.

DOI: https://doi.org/10.1158/0008-5472.CAN-17-0885

Published: 01 October 2017

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Includes: Supplementary data

Journal Articles

Utility of Genomic Analysis In Circulating Tumor DNA from Patients with Carcinoma of Unknown Primary

Shumei Kato, Nithya Krishnamurthy, Kimberly C. Banks, Pradip De, Kirstin Williams, Casey Williams, Brian Leyland-Jones, Scott M. Lippman, Richard B. Lanman, Razelle Kurzrock

Cancer Res (2017) 77 (16): 4238–4246.

DOI: https://doi.org/10.1158/0008-5472.CAN-17-0628

Published: 14 August 2017

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Includes: Supplementary data

Journal Articles

Abstract 5692: Cross-platform detection and quantification of actionable mutations in cell-free DNA shows high concordance and correlation between next-generation sequencing and droplet digital PCR

Bryan C. Ulrich, Rebecca J. Nagy, Justin I. Odegaard, Richard B. Lanman, Geoffrey R. Oxnard, Cloud P. Paweletz

Cancer Res (2017) 77 (13_Supplement): 5692.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5692

Published: 01 July 2017

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Journal Articles

Abstract 5394: The clinical impact of multiplex ctDNA gene analysis in lung cancer

Smadar Geva, Anna Belilovski Rozenblum, Tal Twito, Addie Dvir, Lior Soussan-Gutman, Maya Ilouze, Laila C. Roisman, Elizabeth Dudnik, Alona Zer, Richard B. Lanman, Nir Peled

Cancer Res (2017) 77 (13_Supplement): 5394.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5394

Published: 01 July 2017

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Journal Articles

Abstract 5684: NSABP FC-7 correlative study: HER2 amplification (amp) in circulating cell-free DNA (cfDNA) in metastatic colorectal cancer (mCRC) resistant to anti-EGFR therapy (tx)

S. Rim Kim, Ashok Srinivasan, Carmen J. Allegra, Samuel Jacobs, Rebecca J. Nagy, Richard B. Lanman, AmirAli Talasaz, Patrick Gavin, Rekha Pal, Peter C. Lucas, Kay Pogue-Geile

Cancer Res (2017) 77 (13_Supplement): 5684.

DOI: https://doi.org/10.1158/1538-7445.AM2017-5684

Published: 01 July 2017

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NARROW

Abstract PS5-02: Assessment of early ctDNA dynamics to predict efficacy of targeted therapies in metastatic breast cancer: Results from plasmaMATCH trial

Abstract 734: Monitoring of dynamic changes and clonal evolution in circulating tumor DNA from patients with IDH-mutated cholangiocarcinoma treated with IDH inhibitors

Abstract P4-10-15: PIK3CA mutational analysis using cell-free DNA next-generation sequencing detects activating mutations that may be missed with targeted hot-spot testing

Abstract P5-01-06: Cell-free DNA (cfDNA) analysis of ESR1-mutant advanced breast cancer (aBC): Impact of subsequent therapy on mutation persistence

Abstract LB-118: Resistance to TRK inhibition mediated by convergent MAP kinase pathway activation

Abstract 2509: Analysis of clonal hematopoiesis-associated mutations in the cell-free DNA of advanced cancer patients

Abstract 435: Cell-free circulating tumor DNA (ctDNA) detects somatic copy number loss in homologous recombination repair genes

Abstract 450: Novel genomic differences in cell-free circulating tumor DNA (cfDNA) profiles of early versus older onset colorectal cancer (CRC)

Abstract 3404: Landscape and genomic correlates of ctDNA-based tumor mutational burden across six solid tumor types

Abstract 936: Analysis of cell-free DNA from 32,991 advanced cancers reveals novel co-occurring activating RET alterations and oncogenic signaling pathway aberrations

Abstract 5533: Cell-free DNA sequencing in ERBB2-mutant breast cancer patients treated with neratinib and fulvestrant: Exploratory analysis from the Phase 2 SUMMIT ‘basket' trial

Abstract 5603: Analytical validation of a comprehensive 500-gene ctDNA panel designed for immuno-oncology and DNA damage research

Abstract 4272: A novel approach to differentiation of somatic vs. germline variants in liquid biopsies using a betabinomial model

Abstract 3662: Cell-free DNA sequencing demonstrates persistence of nucleic acid-based therapy—opportunities for detection and monitoring

Abstract 2190: A method for differentiating clonal driver mutations from subclonal emerging resistance mutations in circulating cell-free DNA

Genomic Alterations in Circulating Tumor DNA from Diverse Cancer Patients Identified by Next-Generation Sequencing

Utility of Genomic Analysis In Circulating Tumor DNA from Patients with Carcinoma of Unknown Primary

Abstract 5692: Cross-platform detection and quantification of actionable mutations in cell-free DNA shows high concordance and correlation between next-generation sequencing and droplet digital PCR

Abstract 5394: The clinical impact of multiplex ctDNA gene analysis in lung cancer

Abstract 5684: NSABP FC-7 correlative study: HER2 amplification (amp) in circulating cell-free DNA (cfDNA) in metastatic colorectal cancer (mCRC) resistant to anti-EGFR therapy (tx)

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