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Reiner Strick
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Journal Articles

Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a TP53-Dependent Manner

James I. McDonald, Noor Diab, Elisa Arthofer, Melissa Hadley, Tomas Kanholm, Uzma Rentia, Stephanie Gomez, Angela Yu, Erin E. Grundy, Olivia Cox, Michael J. Topper, Xiaoyun Xing, Pamela L. Strissel, Reiner Strick, Ting Wang, Stephen B. Baylin, Katherine B. Chiappinelli
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5176–5189.
https://doi.org/10.1158/0008-5472.CAN-20-4243
Published: 17 October 2021
View article titled, Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <em>TP53</em>-Dependent Manner
Open the PDF for Epigenetic Therapies in Ovarian Cancer Alter Repetitive Element Expression in a <em>TP53</em>-Dependent Manner in another window
Includes: Supplementary data
Journal Articles

Bladder Tumor Subtype Commitment Occurs in Carcinoma In Situ Driven by Key Signaling Pathways Including ECM Remodeling

Adrian Wullweber, Reiner Strick, Fabienne Lange, Danijel Sikic, Helge Taubert, Sven Wach, Bernd Wullich, Simone Bertz, Veronika Weyerer, Robert Stoehr, Johannes Breyer, Maximilian Burger, Arndt Hartmann, Pamela L. Strissel, Markus Eckstein
Journal: Cancer Research
Cancer Res (2021) 81 (6): 1552–1566.
https://doi.org/10.1158/0008-5472.CAN-20-2336
Published: 15 March 2021
View article titled, Bladder Tumor Subtype Commitment Occurs in Carcinoma <em>In Situ</em> Driven by Key Signaling Pathways Including ECM Remodeling
Open the PDF for Bladder Tumor Subtype Commitment Occurs in Carcinoma <em>In Situ</em> Driven by Key Signaling Pathways Including ECM Remodeling in another window
Includes: Supplementary data
Journal Articles

Abstract LB-098: Sequential azacitidine and histone deacetylase inhibition induces a potent antitumor response in Kras G12D mouse model of NSCLC

Michael Topper, Michelle Vaz, Katherine Chiappinelli, Christina DeStefano Shields, Alyssa Wenzel, Cynthia Zahnow, Pam Strissel, Reiner Strick, Stephen Baylin
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): LB-098.
https://doi.org/10.1158/1538-7445.AM2017-LB-098
Published: 01 July 2017
View article titled, Abstract LB-098: Sequential azacitidine and histone deacetylase inhibition induces a potent antitumor response in Kras G12D mouse model of NSCLC
Journal Articles

Abstract 4019: Inhibiting DNA methylation causes an interferon response in cancer cells via endogenous retroviruses and recruits immune cells to the tumor microenvironment to sensitize to immune therapy

Katherine B. Chiappinelli, Meredith L. Stone, Michael J. Topper, Lauren Murphy, Pamela L. Strissel, Reiner Strick, Cynthia A. Zahnow, Stephen B. Baylin
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4019.
https://doi.org/10.1158/1538-7445.AM2016-4019
Published: 15 July 2016
View article titled, Abstract 4019: Inhibiting DNA methylation causes an interferon response in cancer cells via endogenous retroviruses and recruits immune cells to the tumor microenvironment to sensitize to immune therapy
Journal Articles

Abstract B32: Inhibiting DNA methylation causes an interferon response in cancer via dsRNA including endogenous retroviruses

Katherine B. Chiappinelli, Pamela L. Strissel, Alexis Desrichard, Huili Li, Christine Henke, Benjamin Akman, Alexander Hein, Neal S. Rote, Leslie M. Cope, Alexandra Snyder, Vladimir Makarov, Sadna Budhu, Jedd Wolchok, Cynthia A. Zahnow, Taha Mergoub, Timothy A. Chan, Reiner Strick, Stephen B. Baylin
Journal: Cancer Research
Cancer Res (2016) 76 (2_Supplement): B32.
https://doi.org/10.1158/1538-7445.CHROMEPI15-B32
Published: 14 January 2016
View article titled, Abstract B32: Inhibiting DNA methylation causes an interferon response in cancer via dsRNA including endogenous retroviruses
Journal Articles

Abstract NG07: Immunomodulatory and tumor cell killing effects of the demethylating agent 5-azacytidine in ovarian cancer

Katherine B. Chiappinelli, Pamela Strissel, Ray-Whay Chiu Yen, Huili Li, Meredith L. Stone, Lauren Murphy, Benjamin Akman, Cynthia A. Zahnow, Reiner Strick, Stephen B. Baylin
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): NG07.
https://doi.org/10.1158/1538-7445.AM2015-NG07
Published: 01 August 2015
View article titled, Abstract NG07: Immunomodulatory and tumor cell killing effects of the demethylating agent 5-azacytidine in ovarian cancer
Journal Articles

Abstract 4800: Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: emergence of new molecular targets.

Pamela L. Strissel, Matthias Ruebner, Falk Thiel, David Wachter, Arif B. Ekici, Florentine Koppitz, Matthias W. Beckmann, Reiner Strick
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 4800.
https://doi.org/10.1158/1538-7445.AM2013-4800
Published: 15 April 2013
View article titled, Abstract 4800: Reactivation of codogenic endogenous retroviral (ERV) envelope genes in human endometrial carcinoma and prestages: emergence of new molecular targets.
Journal Articles

Abstract 4894: Human endogenous retroviral over expression in endometrial carcinoma is due to hypomethylation of the 5′LTR

Matthias Ruebner, Reiner Strick, Franziska Dietz, Stephan Ellmann, Eli Stiegler, Falk Thiel, Matthias W. Beckmann, Pamela L. Strissel
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4894.
https://doi.org/10.1158/1538-7445.AM10-4894
Published: 15 April 2010
View article titled, Abstract 4894: Human endogenous retroviral over expression in endometrial carcinoma is due to hypomethylation of the 5′LTR
Journal Articles

Proliferation and cell-cell fusion of endometrial carcinoma are induced by the human endogenous retroviral Syncytin and regulated by TGF-β

Pamela L. Strissel, Sven Ackermann, Matthias W. Beckmann, Reiner Strick
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 85.
Published: 15 April 2006
View article titled, Proliferation and cell-cell fusion of endometrial carcinoma are induced by the human endogenous retroviral Syncytin and regulated by TGF-β