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Rebecca L. Schmidt
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Journal Articles

Abstract A1: SIAH E3 ligase as a novel anticancer drug target to inhibit RAS‐mediated tumorigenesis and metastasis in human cancer cells

Yang Liao, Cheol Hong Park, Rebecca L. Schmidt, Atique U. Ahmed, Rie Takahashi, Amy H. Tang
Journal: Cancer Research
Cancer Res (2009) 69 (23_Supplement): A1.
https://doi.org/10.1158/0008-5472.FBCR09-A1
Published: 28 October 2014
View article titled, Abstract A1: SIAH E3 ligase as a novel anticancer drug target to inhibit RAS‐mediated tumorigenesis and metastasis in human cancer cells
Journal Articles

Abstract B14: Attacking the Achilles' heel in the oncogenic K-RAS signaling pathway to block tumorigenesis and metastasis in human cancers

Amy H. Tang, Yang Liao, Cheol Hong Park, Minglei Bian, Rebecca L. Schmidt, Atique U. Ahmed, Rie Takahashi, John A. Crooks, Zandra Walton
Journal: Cancer Research
Cancer Res (2011) 71 (18_Supplement): B14.
https://doi.org/10.1158/1538-7445.FBCR11-B14
Published: 28 October 2014
View article titled, Abstract B14: Attacking the Achilles' heel in the oncogenic K-RAS signaling pathway to block tumorigenesis and metastasis in human cancers
Journal Articles

Abstract 1965: Inhibiting SIAH2 E3 ligase function disrupts focal adhesion and cell junction, inhibits cell mobility and attachment, and blocks tumor invasion and metastasis in oncogenic K-Ras-driven tumors

Ming Bian, Yang Liao, Rebecca L. Schmidt, Monicah M. Njogu, Rie Takahashi, Zandra E. Walton, Amy H. Tang
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1965.
https://doi.org/10.1158/1538-7445.AM2014-1965
Published: 01 October 2014
View article titled, Abstract 1965: Inhibiting SIAH2 E3 ligase function disrupts focal adhesion and cell junction, inhibits cell mobility and attachment, and blocks tumor invasion and metastasis in oncogenic K-Ras-driven tumors
Journal Articles

Abstract C62: Attacking the most downstream “gatekeeper” signaling module in the oncogenic ERBB/K-RAS signaling pathway to block tumorigenesis and metastasis in human cancer

Minglei Bian, Yang Liao, Vasilena Zheleva, Xiaofei Gao, Zena M. Urban, Monicah M. Njogu, Justin J. Odanga, Andrew J. Isbell, Rebecca L. Schmidt, Rie Takahashi, Roger R. Perry, Richard A. Hoefer, Thomas C. Smyrk, Gloria M. Petersen, Amy H. Tang
Journal: Cancer Research
Cancer Res (2013) 73 (19_Supplement): C62.
https://doi.org/10.1158/1538-7445.FBCR13-C62
Published: 15 May 2014
View article titled, Abstract C62: Attacking the most downstream “gatekeeper” signaling module in the oncogenic ERBB/K-RAS signaling pathway to block tumorigenesis and metastasis in human cancer
Journal Articles

Abstract A88: SIAH2-mediated proteolysis of LIM domain proteins induces invasion and metastasis in response to oncogenic K-RAS activation in human pancreatic cancer cells.

Amy H. Tang, Yang Liao, Rebecca L. Schmidt, Zandra E. Walton, Rie Takahashi
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): A88.
https://doi.org/10.1158/1538-7445.PANCA2012-A88
Published: 03 April 2014
View article titled, Abstract A88: SIAH2-mediated proteolysis of LIM domain proteins induces invasion and metastasis in response to oncogenic K-RAS activation in human pancreatic cancer cells.
Journal Articles

Abstract 205: SIAH2 modulates focal adhesion and cell junction proteins in response to oncogenic ERBB/K-RAS activation to promote cancer cell dissemination, invasion and metastasis.

Minglei Bian, Yang Liao, Rebecca L. Schmidt, Zandra E. Walton, Amy H. Tang
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 205.
https://doi.org/10.1158/1538-7445.AM2013-205
Published: 15 April 2013
View article titled, Abstract 205: SIAH2 modulates focal adhesion and cell junction proteins in response to oncogenic ERBB/K-RAS activation to promote cancer cell dissemination, invasion and metastasis.
Journal Articles

Abstract 2335: Oncogenic K-RAS activation promotes cell motility, invasion, tumor growth and cancer metastasis via its most downstream signaling module, the SIAH2-dependent proteolytic machinery, in the highly aggressive and metastatic human cancer cells

Yang Liao, Rebecca L. Schmidt, Zandra E. Walton, Rie Takahashi, Amy H. Tang
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2335.
https://doi.org/10.1158/1538-7445.AM2011-2335
Published: 15 April 2011
View article titled, Abstract 2335: Oncogenic K-RAS activation promotes cell motility, invasion, tumor growth and cancer metastasis via its most downstream signaling module, the SIAH2-dependent proteolytic machinery, in the highly aggressive and metastatic human cancer cells
Journal Articles

Inhibition of RAS-Mediated Transformation and Tumorigenesis by Targeting the Downstream E3 Ubiquitin Ligase Seven in Absentia Homologue

Rebecca L. Schmidt, Cheol Hong Park, Atique U. Ahmed, Justin H. Gundelach, Nanette R. Reed, Shen Cheng, Bruce E. Knudsen, Amy H. Tang
Journal: Cancer Research
Cancer Res (2007) 67 (24): 11798–11810.
https://doi.org/10.1158/0008-5472.CAN-06-4471
Published: 18 December 2007
View article titled, Inhibition of RAS-Mediated Transformation and Tumorigenesis by Targeting the Downstream E3 Ubiquitin Ligase Seven in Absentia Homologue
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Includes: Supplementary data