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Rami I. Aqeilan
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Journal Articles

Correction: Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity

Zaidoun Salah, Gerry Melino, Rami I. Aqeilan
Journal: Cancer Research
Cancer Res (2019) 79 (11): 3007.
https://doi.org/10.1158/0008-5472.CAN-19-1086
Published: 03 June 2019
View article titled, Correction: Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity
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Journal Articles

WWOX Inhibits Metastasis of Triple-Negative Breast Cancer Cells via Modulation of miRNAs

Saleh Khawaled, Sung Suk Suh, Suhaib K. Abdeen, Jonathan Monin, Rosario Distefano, Giovanni Nigita, Carlo M. Croce, Rami I. Aqeilan
Journal: Cancer Research
Cancer Res (2019) 79 (8): 1784–1798.
https://doi.org/10.1158/0008-5472.CAN-18-0614
Published: 15 April 2019
View article titled, WWOX Inhibits Metastasis of Triple-Negative Breast Cancer Cells via Modulation of miRNAs
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Includes: Supplementary data
Journal Articles

Microenvironmental Cues Determine Tumor Cell Susceptibility to Neutrophil Cytotoxicity

Maya Gershkovitz, Tanya Fainsod-Levi, Saleh Khawaled, Merav E. Shaul, Ronit V. Sionov, Leonor Cohen-Daniel, Rami I. Aqeilan, Yoav D. Shaul, Zvi G. Fridlender, Zvi Granot
Journal: Cancer Research
Cancer Res (2018) 78 (17): 5050–5059.
https://doi.org/10.1158/0008-5472.CAN-18-0540
Published: 04 September 2018
View article titled, Microenvironmental Cues Determine Tumor Cell Susceptibility to Neutrophil Cytotoxicity
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Includes: Supplementary data
Journal Articles

TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells

Maya Gershkovitz, Yaki Caspi, Tanya Fainsod-Levi, Ben Katz, Janna Michaeli, Saleh Khawaled, Shaya Lev, Lola Polyansky, Merav E. Shaul, Ronit V. Sionov, Leonor Cohen-Daniel, Rami I. Aqeilan, Yoav D. Shaul, Yasuo Mori, Rotem Karni, Zvi G. Fridlender, Alexander M. Binshtok, Zvi Granot
Journal: Cancer Research
Cancer Res (2018) 78 (10): 2680–2690.
https://doi.org/10.1158/0008-5472.CAN-17-3614
Published: 14 May 2018
View article titled, TRPM2 Mediates Neutrophil Killing of Disseminated Tumor Cells
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Includes: Supplementary data
Journal Articles

WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma

Sara Del Mare, Hussam Husanie, Ortal Iancu, Mohammad Abu-Odeh, Konstantinos Evangelou, Francesca Lovat, Stefano Volinia, Jonathan Gordon, Gail Amir, Janet Stein, Gary S. Stein, Carlo M. Croce, Vassilis Gorgoulis, Jane B. Lian, Rami I. Aqeilan
Journal: Cancer Research
Cancer Res (2016) 76 (20): 6107–6117.
https://doi.org/10.1158/0008-5472.CAN-16-0621
Published: 13 October 2016
View article titled, WWOX and p53 Dysregulation Synergize to Drive the Development of Osteosarcoma
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Includes: Supplementary data
Journal Articles

miRNA Signatures Associate with Pathogenesis and Progression of Osteosarcoma

Kevin B. Jones, Zaidoun Salah, Sara Del Mare, Marco Galasso, Eugenio Gaudio, Gerard J. Nuovo, Francesca Lovat, Kimberly LeBlanc, Jeff Palatini, R. Lor Randall, Stefano Volinia, Gary S. Stein, Carlo M. Croce, Jane B. Lian, Rami I. Aqeilan
Journal: Cancer Research
Cancer Res (2012) 72 (7): 1865–1877.
https://doi.org/10.1158/0008-5472.CAN-11-2663
Published: 01 April 2012
View article titled, miRNA Signatures Associate with Pathogenesis and Progression of Osteosarcoma
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Includes: Supplementary data
Journal Articles

Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity

Zaidoun Salah, Gerry Melino, Rami I. Aqeilan
Journal: Cancer Research
Cancer Res (2011) 71 (5): 2010–2020.
https://doi.org/10.1158/0008-5472.CAN-10-3516
Published: 01 March 2011
View article titled, Negative Regulation of the Hippo Pathway by E3 Ubiquitin Ligase ITCH Is Sufficient to Promote Tumorigenicity
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Includes: Supplementary data
Journal Articles

Frequent Attenuation of the WWOX Tumor Suppressor in Osteosarcoma Is Associated with Increased Tumorigenicity and Aberrant RUNX2 Expression

Kyle C. Kurek, Sara Del Mare, Zaidoun Salah, Suhaib Abdeen, Hussain Sadiq, Suk-hee Lee, Eugenio Gaudio, Nicola Zanesi, Kevin B. Jones, Barry DeYoung, Gail Amir, Mark Gebhardt, Matthew Warman, Gary S. Stein, Janet L. Stein, Jane B. Lian, Rami I. Aqeilan
Journal: Cancer Research
Cancer Res (2010) 70 (13): 5577–5586.
https://doi.org/10.1158/0008-5472.CAN-09-4602
Published: 30 June 2010
View article titled, Frequent Attenuation of the WWOX Tumor Suppressor in Osteosarcoma Is Associated with Increased Tumorigenicity and Aberrant RUNX2 Expression
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Includes: Supplementary data
Journal Articles

Abstract #2637: Regulation of expression of multiple miRNAs defines the cellular response to non genotoxic p53 activation in multiple myeloma cells

Flavia Pichiorri, Suh Sung-Suk, Cristian Taccioli, Craig Hofmeister, Don Benson, Michael Kuehl, Reinhold Munker, Kay Huebner, Rami I. Aqeilan, Carlo M Croce
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2637.
Published: 01 May 2009
View article titled, Abstract #2637: Regulation of expression of multiple miRNAs defines the cellular response to non genotoxic p53 activation in multiple myeloma cells
Journal Articles

Microrna signatures in multiple myeloma

Flavia Pichiorri, Sung-Suk Suh, Marco Ladetto, Reinhold Munker, Tiziana Palumbo, John Hagan, Alder Hansjuerg, Stefano Volinia, Antonio Palumbo, Rami I Aqeilan, Carlo M Croce
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5047.
Published: 01 May 2008
View article titled, Microrna signatures in multiple myeloma
Journal Articles

Association of Wwox with ErbB4 in Breast Cancer

Rami I. Aqeilan, Valentina Donati, Eugenio Gaudio, Milena S. Nicoloso, Maria Sundvall, Anna Korhonen, Johan Lundin, Jorma Isola, Marius Sudol, Heikki Joensuu, Carlo M. Croce, Klaus Elenius
Journal: Cancer Research
Cancer Res (2007) 67 (19): 9330–9336.
https://doi.org/10.1158/0008-5472.CAN-07-2147
Published: 01 October 2007
View article titled, Association of Wwox with ErbB4 in Breast Cancer
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Includes: Supplementary data
Journal Articles

Inactivation of the Wwox Gene Accelerates Forestomach Tumor Progression In vivo

Rami I. Aqeilan, John P. Hagan, Haifa A. Aqeilan, Flavia Pichiorri, Louise Y.Y. Fong, Carlo M. Croce
Journal: Cancer Research
Cancer Res (2007) 67 (12): 5606–5610.
https://doi.org/10.1158/0008-5472.CAN-07-1081
Published: 15 June 2007
View article titled, Inactivation of the <em>Wwox</em> Gene Accelerates Forestomach Tumor Progression <em>In vivo</em>
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Journal Articles

Physical Association with WWOX Suppresses c-Jun Transcriptional Activity

Eugenio Gaudio, Alexey Palamarchuk, Tiziana Palumbo, Francesco Trapasso, Yuri Pekarsky, Carlo M. Croce, Rami I. Aqeilan
Journal: Cancer Research
Cancer Res (2006) 66 (24): 11585–11589.
https://doi.org/10.1158/0008-5472.CAN-06-3376
Published: 18 December 2006
View article titled, Physical Association with WWOX Suppresses c-Jun Transcriptional Activity
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Journal Articles

Tal1 Transgenic Expression Reveals Absence of B Lymphocytes

Alexey Palamarchuk, Nicola Zanesi, Rami I. Aqeilan, Alexey Efanov, Vadim Maximov, Urmila Santanam, John P. Hagan, Carlo M. Croce, Yuri Pekarsky
Journal: Cancer Research
Cancer Res (2006) 66 (12): 6014–6017.
https://doi.org/10.1158/0008-5472.CAN-06-0937
Published: 15 June 2006
View article titled, Tal1 Transgenic Expression Reveals Absence of B Lymphocytes
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Journal Articles

In vitro Parkin gene restoration does not induce apoptosis in human lung, breast, ovarian, and cervical cancer cell lines

Muller Fabbri, Amelia Cimmino, Francesco Trapasso, Rami I. Aqeilan, Carlo M. Croce
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 782.
Published: 15 April 2006
View article titled, <em>In vitro</em> Parkin gene restoration does not induce apoptosis in human lung, breast, ovarian, and cervical cancer cell lines
Journal Articles

Association of Paclitaxel and recombinant adenoviral restoration of the Parkin gene does not increase apoptosis in human lung cancer cell lines

Amelia Cimmino, Muller Fabbri, Francesco Trapasso, Rami I. Aqeilan, Carlo M. Croce
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 592–593.
Published: 15 April 2006
View article titled, Association of Paclitaxel and recombinant adenoviral restoration of the <em>Parkin</em> gene does not increase apoptosis in human lung cancer cell lines
Journal Articles

Akt phosphorylates and regulates Pdcd4 tumor suppressor protein

Alexey Palamarchuk, Alexey Efanov, Vadim Maximov, Rami I. Aqeilan, Carlo M. Croce, Yuri Pekarsky
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 967.
Published: 15 April 2006
View article titled, Akt phosphorylates and regulates Pdcd4 tumor suppressor protein
Journal Articles

Akt Phosphorylates and Regulates Pdcd4 Tumor Suppressor Protein

Alexey Palamarchuk, Alexey Efanov, Vadim Maximov, Rami I. Aqeilan, Carlo M. Croce, Yuri Pekarsky
Journal: Cancer Research
Cancer Res (2005) 65 (24): 11282–11286.
https://doi.org/10.1158/0008-5472.CAN-05-3469
Published: 15 December 2005
View article titled, Akt Phosphorylates and Regulates Pdcd4 Tumor Suppressor Protein
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Journal Articles

WW Domain–Containing Proteins, WWOX and YAP, Compete for Interaction with ErbB-4 and Modulate Its Transcriptional Function

Rami I. Aqeilan, Valentina Donati, Alexey Palamarchuk, Francesco Trapasso, Mohamed Kaou, Yuri Pekarsky, Marius Sudol, Carlo M. Croce
Journal: Cancer Research
Cancer Res (2005) 65 (15): 6764–6772.
https://doi.org/10.1158/0008-5472.CAN-05-1150
Published: 01 August 2005
View article titled, WW Domain–Containing Proteins, WWOX and YAP, Compete for Interaction with ErbB-4 and Modulate Its Transcriptional Function
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Journal Articles

Akt Phosphorylates Tal1 Oncoprotein and Inhibits Its Repressor Activity

Alexey Palamarchuk, Alexey Efanov, Vadim Maximov, Rami I. Aqeilan, Carlo M. Croce, Yuri Pekarsky
Journal: Cancer Research
Cancer Res (2005) 65 (11): 4515–4519.
https://doi.org/10.1158/0008-5472.CAN-05-0751
Published: 01 June 2005
View article titled, Akt Phosphorylates Tal1 Oncoprotein and Inhibits Its Repressor Activity
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