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Rameen Beroukhim
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Journal Articles

Abstract 2173: Ancestry bias in CRISPR guide design impedes discovery of genetic dependencies

Sean Alexander Misek, Aaron Fultineer, Jeremie Kalfon, Javad Noorbakhsh, Isabella Boyle, Joshua Dempster, Lia Petronio, Katherine Huang, James McFarland, Rameen Beroukhim, Jesse Boehm
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2173.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2173
Published: 15 June 2022
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Abstract 2710: Associations between structural variant signatures and drug sensitivity in cell lines

Simona Dalin, Frank Dubois, Shu Zhang, Alexander Crane, Jeremie Kalfon, Javad Noorbakhsh, Rameen Beroukhim
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2710.
DOI: https://doi.org/10.1158/1538-7445.AM2022-2710
Published: 15 June 2022
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Abstract 1166: Leveraging existing data to identify ancestry-associated features across multiple cancer types

Jian Carrot-Zhang, Justin Newberg, Garrett Frampton, Rameen Beroukhim
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1166.
DOI: https://doi.org/10.1158/1538-7445.AM2022-1166
Published: 15 June 2022
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Abstract 2135: Functional models of chromosome arm aneuploidies in lung squamous cell carcinoma

Alison Marie Taylor, Sejal Jain, Juliann Shih, Andrew D. Cherniack, Rameen Beroukhim, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2135.
DOI: https://doi.org/10.1158/1538-7445.AM2021-2135
Published: 01 July 2021
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Journal Articles

Abstract 5705: Mechanisms and therapeutic implications of hypermutation in gliomas

Mehdi Touat, Yvonne Y. Li, Adam N. Boynton, Liam F. Spurr, Bryan Iorgulescu, Craig L. Bohrson, Isidro Cortes-Ciriano, Jack E. Geduldig, Kristine Pelton, Mary J. Lim-Fat, Sangita Pal, Shakti H. Ramkissoon, Frank Dubois, Charlotte Bellamy, Naomi Currimjee, Kenin Qian, Seth Malinowski, Aniket Shetty, Kin-Hoe Chow, Maïté Verreault, Erell Guillerm, Samy Ammari, Frédéric Beuvon, Karima Mokhtari, Agusti Alentorn, Caroline Dehais, Caroline Houillier, Florence Laigle-Donadey, Dimitri Psimaras, Alexandre Carpentier, Philippe Cornu, Laurent Capelle, Bertrand Mathon, Jill S. Barnholtz-Sloan, Arnab Chakravarti, Wenya L. Bi, Garrett M. Frampton, Marc Sanson, Brian M. Alexander, Andrew Cherniack, Patrick Y. Wen, David A. Reardon, Aurelien Marabelle, Peter J. Park, Ahmed Idbaih, Rameen Beroukhim, Pratiti Bandopadhayay, Franck Bielle, Keith L. Ligon
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5705.
DOI: https://doi.org/10.1158/1538-7445.AM2020-5705
Published: 15 August 2020
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Journal Articles

Abstract A44: Functional models of chromosome arm-level aneuploidies in cancer

Alison M. Taylor, Sejal Jain, Juliann Shih, Andrew D. Cherniack, Rameen Beroukhim, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2020) 80 (11_Supplement): A44.
DOI: https://doi.org/10.1158/1538-7445.CAMODELS2020-A44
Published: 02 June 2020
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Journal Articles

Abstract 3647: Single cell RNA sequencing reveals mitogenic and progenitor gene programs inBRAF-rearranged pilocytic astrocytomas

Zachary J. Reitman, Brenton Paolella, Guillaume Bergthold, Kristine Pelton, Robert Jones, Sarah Becker, Claire E. Sinai, Haley Malkin, Ying Huang, Leslie Grimmett, Zachary T. Herbert, Yu Sun, Jessica Weatherbee, John Alberta, John Daley, Orit Rozenblatt-Rosen, Rosalind Segal, Daphne Haas-Kogan, Mariella G. Filbin, Mario L. Suva, Aviv Regev, Charles Stiles, Mark W. Kieran, Liliana Goumnerova, Keith L. Ligon, Alex K. Shalek, Pratiti Bandopadhayay, Rameen Beroukhim
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3647.
DOI: https://doi.org/10.1158/1538-7445.AM2019-3647
Published: 01 July 2019
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Abstract B18: Modeling renal medullary carcinomas identifies druggable vulnerabilities in SMARCB1-deficient cancers

Andrew L. Hong, Yuen-Yi Tseng, Bryan D. Kynnap, Mihir B. Doshi, Jeremiah Wala, Gabriel Sandoval, Alanna J. Church, Elizabeth Mullen, Cigall Kadoch, Charles W.M. Roberts, Rameen Beroukhim, Jesse S. Boehm, William C. Hahn
Journal: Cancer Research
Cancer Res (2018) 78 (19_Supplement): B18.
DOI: https://doi.org/10.1158/1538-7445.PEDCA17-B18
Published: 01 October 2018
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Journal Articles

Abstract 1028: Patient-derived xenografts undergo mouse-specific tumor evolution

Uri Ben-David, Gavin Ha, Yuen-Yi Tseng, Noah F. Greenwald, Coyin Oh, Juliann Shih, James M. McFarland, Bang Wong, Jesse S. Boehm, Rameen Beroukhim, Todd R. Golub
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1028.
DOI: https://doi.org/10.1158/1538-7445.AM2018-1028
Published: 01 July 2018
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Journal Articles

Abstract 214: Genetic and transcriptional instability alters cell line drug response

Uri Ben-David, Ben Siranosian, Gavin Ha, Helen Tang, Nicholas J. Lyons, Robert Burns, Anwesha Nag, Beth Cimini, Peter Tsvetkov, Andrew A. Tubelli, Bang Wong, Aaron R. Thorner, Joshua Bittker, Matthew Meyerson, Rameen Beroukhim, Todd R. Golub
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 214.
DOI: https://doi.org/10.1158/1538-7445.AM2018-214
Published: 01 July 2018
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Journal Articles

Abstract 2352: Defining a pediatric cancer dependency map

Neekesh V. Dharia, Clare Malone, Amanda Balboni Iniguez, Lillian Guenther, Liying Chen, Gabriela Alexe, Adam D. Durbin, Mark W. Zimmerman, Andrew Hong, Pratiti Bandopadhayay, Mariella G. Filbin, Thomas Howard, Brenton Paolella, Iris Fung, Josephine Lee, Phil Montgomery, John M. Krill-Burger, Brian J. Abraham, Jennifer Roth, David E. Root, Richard A. Young, A. Thomas Look, Rameen Beroukhim, Jesse S. Boehm, William C. Hahn, Todd R. Golub, Aviad Tsherniak, Francisca Vazquez, Kimberly Stegmaier
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2352.
DOI: https://doi.org/10.1158/1538-7445.AM2018-2352
Published: 01 July 2018
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Journal Articles

Abstract 3003: Loss of heterozygosity of essential genes represents a novel class of cancer vulnerabilities

Caitlin A. Nichols, Brenton R. Paolella, William J. Gibson, Meredith S. Brown, Laura M. Urbanski, Jack A. Kosmicki, John P. Busanovich, Ashton C. Berger, Galen F. Gao, Andrew D. Cherniack, Rameen Beroukhim
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3003.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3003
Published: 01 July 2018
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Abstract 3002: Genome engineering approaches to generate models of chromosome arm-level cancer aneuploidy

Alison Marie Taylor, Xiaoyang Zhang, Juliann Shih, Gavin Ha, Galen F. Gao, Ashton C. Berger, Andrew D. Cherniack, Rameen Beroukhim, Matthew Meyerson
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3002.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3002
Published: 01 July 2018
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Abstract 3000: Pervasive intra-tumour heterogeneity and subclonal selection across cancer types

Stefan Dentro, Ignaty Leshchiner, Kerstin Haase, Jeff Wintersinger, Amit Deshwar, Maxime Tarabichi, Yulia Rubanova, Kaixian Yu, Ignacio Vázquez García, Geoff Macintyre, Kortine Kleinheinz, Dimitri Livitz, Salem Malikic, Nilgun Donmez, Subhajit Sengupta, Yuan Ji, Jonas Demeulemeester, Pavana Anur, Clemency Jolly, Marek Cmero, Daniel Rosebrock, Steve Schumacher, Yu Fan, Matthew Fittall, Xiaotong Yao, Juhee Lee, Matthias Schlesner, Hongtu Zhu, David Adams, Gad Getz, Paul Boutros, Marcin Imielinski, Rameen Beroukhim, Cenk Sahinalp, Martin Peifer, Inigo Martincorena, Florian Markowetz, Ville Mustonen, Ke Yuan, Moritz Gerstung, Wenyi Wang, Paul Spellman, Quaid Morris, David Wedge, Peter Van Loo
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 3000.
DOI: https://doi.org/10.1158/1538-7445.AM2018-3000
Published: 01 July 2018
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Abstract 218: The evolutionary history of 2,658 cancers

Clemency Jolly, Moritz Gerstung, Ignaty Leshchiner, Stefan C. Dentro, Santiago Gonzalez, Thomas J. Mitchell, Yulia Rubanova, Pavana Anur, Daniel Rosebrock, Kaixian Yu, Maxime Tarabichi, Amit Deshwar, Jeff Wintersinger, Kortine Kleinheinz, Ignacio Vásquez-García, Kerstin Haase, Subhajit Sengupta, Geoff Macintyre, Salem Malikic, Nilgun Donmez, Dimitri G. Livitz, Mark Cmero, Jonas Demeulemeester, Steve Schumacher, Yu Fan, Xiaotong Yao, Juhee Lee, Matthias Schlesner, Paul C. Boutros, David D. Bowtell, Hongtu Zhu, Gad Getz, Marcin Imielinski, Rameen Beroukhim, S Cenk Sahinalp, Yuan Ji, Martin Peifer, Florian Markowetz, Ville Mustonen, Ke Juan, Wenyi Wang, Quaid D. Morris, Paul T. Spellman, David C. Wedge, Peter Van Loo, PCAWG Evolution and Heterogeneity Working Group
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 218.
DOI: https://doi.org/10.1158/1538-7445.AM2018-218
Published: 01 July 2018
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Journal Articles

Abstract 4974: Pharmacogenomic interactions in glioblastoma cell line models

Ruben Ferrer-Luna, Shakti H. Ramkissoon, Karl H. Olausson, Lori A. Ramkissoon, Steven Schumacher, Rebecca Lamothe, Jaime H. Cheah, Kristine Pellton, Sam Haidar, Yun J. Kang, Brenton R. Paolella, Cecile Maire, Wenyu Song, Alice Meng, Ahmed Idbaih, Mikael L. Rinne, David A. Reardon, Patrick Y. Wen, Paul A. Clemons, Stuart L. Schreiber, Alykhan F. Shamji, Rameen Beroukhim, Keith L. Ligon
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4974.
DOI: https://doi.org/10.1158/1538-7445.AM2017-4974
Published: 01 July 2017
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Abstract 4369: Genome-wide copy number dependency analysis identifies partial copy loss of SF3B1 as a novel cancer vulnerability

Brenton R. Paolella, William J. Gibson, Laura M. Urbanski, John A. Alberta, Travis I. Zack, Pratiti Bandopadhayay, Caitlin A. Nichols, Pankaj K. Agarwalla, Meredith S. Brown, Rebecca Lamothe, Yong Yu, Peter S. Choi, Esther A. Obeng, Dirk Heckl, Benjamin L. Ebert, Guo Wei, Belinda Wang, William C. Hahn, Francisca Vazquez, Barbara A. Weir, Charles D. Stiles, Robin Reed, Rameen Beroukhim
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4369.
DOI: https://doi.org/10.1158/1538-7445.AM2016-4369
Published: 15 July 2016
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Journal Articles

Abstract 4372: MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism

Lori Ramkissoon, Pratiti Bandopadhayay, Payal Jain, Guillaume Bergthold, Adam Resnick, Rameen Beroukhim, Keith Ligon
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4372.
DOI: https://doi.org/10.1158/1538-7445.AM2016-4372
Published: 15 July 2016
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Abstract LB-227: Truncal activating MAPK and PI3K pathway alterations and exceptional response to dual pathway inhibition in anaplastic thyroid cancer

William J. Gibson, Daniel T. Ruan, Vera A. Paulson, Justine A. Barletta, Glenn J. Hanna, Stefan Kraft, Antonio Calles, Matthew Nehs, Francis Moore, Amaro Taylor-Weiner, Jeremiah Wala, Travis Zack, Thomas Lee, Fiona Fennessy, Erik Alexander, Tom Thomas, Pasi Jäne, Levi Garraway, Scott Carter, Rameen Beroukhim, Jochen Lorch, Eliezer Van Allen
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-227.
DOI: https://doi.org/10.1158/1538-7445.AM2016-LB-227
Published: 15 July 2016
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Abstract PR04: Genomic characterization of brain metastases reveals branched evolution and metastasis-specific mutations

Priscilla K. Brastianos, Scott L. Carter, Sandro Santagata, Daniel Cahill, Amaro Taylor-Weiner, Robert T. Jones, Eliezer Van Allen, Peleg Horowitz, Keith L. Ligon, William T. Curry, Ian F. Dunn, Paul Van Hummelen, Matthew Meyerson, Levi Garraway, Josep Tabernero, Joan Seoane, Stacey Gabriel, Eric S. Lander, Rameen Beroukhim, Tracy T. Batchelor, Jose Baselga, David N. Louis, William C. Hahn, Gad Getz
Journal: Cancer Research
Cancer Res (2015) 75 (23_Supplement): PR04.
DOI: https://doi.org/10.1158/1538-7445.BRAIN15-PR04
Published: 09 December 2015
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