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Ramachandraiah Gosu
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Journal Articles

Abstract 4388: Novel small molecule on state inhibitor for GTP bound pan-KRAS (G12) mutations

Free
Chandru Gajendran, Naveen M. Sadhu, Ramachandraiah Gosu, Mohammed Zainuddin, Dhanalakshmi Sivanandhan, Sridharan Rajagopal
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 4388.
https://doi.org/10.1158/1538-7445.AM2025-4388
Published: 21 April 2025
View articletitled, Abstract 4388: Novel small molecule on state inhibitor for GTP bound pan-KRAS (G12) mutations
Journal Articles

Abstract 6269: JBI-778, a novel brain-penetrant small molecule PRMT5 inhibitor for treatment of cancer

Free
Dhanalakshmi Sivanandhan, Chandru Gajendran, Naveen Sadhu M, Zainuddin Mohammed, Ramachandraiah Gosu, Divsha Sher, Shahar Mansur, Dinorah Friedmann-Morvinski, Sridharan Rajagopal, Luca Rastelli
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 6269.
https://doi.org/10.1158/1538-7445.AM2023-6269
Published: 04 April 2023
View articletitled, Abstract 6269: JBI-778, a novel brain-penetrant small molecule PRMT5 inhibitor for treatment of cancer
Journal Articles

Abstract B029: LSD1-HDAC6 dual inhibitor JBI-802 is an epigenetic modulating agent with a novel mechanism of action that target MYC amplification in multiple neuroendocrine tumor types

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Dhanalakshmi Sivanandhan, Sridharan Rajagopal, Chandru Gajendran, Naveen Sadhu, Mohd Zainuddin, Ramachandraiah Gosu, Luca Rastelli
Journal: Cancer Research
Cancer Res (2022) 82 (23_Supplement_2): B029.
https://doi.org/10.1158/1538-7445.CancEpi22-B029
Published: 01 December 2022
View articletitled, Abstract B029: LSD1-HDAC6 dual inhibitor JBI-802 is an epigenetic modulating agent with a novel mechanism of action that target MYC amplification in multiple neuroendocrine tumor types
Journal Articles

A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression

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Hui Deng, Cindy Lin, Laura Garcia-Gerique, Shuyu Fu, Zachary Cruz, Erin E. Bonner, Matthew Rosenwasser, Sridharan Rajagopal, M Naveen Sadhu, Chandru Gajendran, Mohd Zainuddin, Ramachandraiah Gosu, Dhanalakshmi Sivanandhan, Miriam A. Shelef, Brian Nam, Dan T. Vogl, Dmitry I. Gabrilovich, Yulia Nefedova
Journal: Cancer Research
Cancer Res (2022) 82 (19): 3561–3572.
https://doi.org/10.1158/0008-5472.CAN-21-4045
Published: 04 October 2022
View articletitled, A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression
Open the PDF for A Novel Selective Inhibitor JBI-589 Targets PAD4-Mediated Neutrophil Migration to Suppress Tumor Progression in another window
Includes: Supplementary data
Journal Articles

Abstract 2646: Novel, isoform selective PAD4 inhibitors for the treatment of cancer

Free
Dhanalakshmi Sivanandhan, Sridharan Rajagopal, Chandru G, Mohd Zainuddin, Naveen Sadhu, Ramachandraiah Gosu, Luca Rastelli, Amir Siddiqui, Sharad Singh, Rudresh G, Sadanand Mullurwar, Saravanan Kandan, Santosh Vishwakarma, Gurulingappa Hallur, Ravi Trivedi, Jeyaraj D A
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2646.
https://doi.org/10.1158/1538-7445.AM2022-2646
Published: 15 June 2022
View articletitled, Abstract 2646: Novel, isoform selective PAD4 inhibitors for the treatment of cancer
Journal Articles

Abstract 5552: Novel, heterocyclic small molecule inhibitors of PD-1 and PD-L1 pathway

Free
Sivanandhan Dhanalakshmi, Shivani Garapaty, Chandregowda Venkateshappa, Guru Pavan Seerapu, Reshma Das, Pradeep Nagaraj, Ronodip Kar, Anuj Kumar Singh, Venkatesha Ashokkumar Venkatesubbiah, Ramakishore VP Putta, Muralidhar Pendyala, Girisha Lokesh, Hari Madaka, Harikrishna Reddy Thummuru, Shikas AP, Prateeksha Anchan, Prathima Bhat, Rudresha G, Mohd Zainuddin, Krishnakumar V, Ramachandraiah Gosu, Rajendra Kristam, Jeyaraj DA, Sriram Rajagopal
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5552.
https://doi.org/10.1158/1538-7445.AM2018-5552
Published: 01 July 2018
View articletitled, Abstract 5552: Novel, heterocyclic small molecule inhibitors of PD-1 and PD-L1 pathway
Journal Articles

Abstract 3509: Novel dual inhibitors of LSD1-HDAC for treatment of cancer

Free
Dhanalakshmi Sivanandhan, Sridharan Rajagopalan, Sreekala Nair, Purushottam Dewang, Durga Prasanna Kumar, Chandrika Mulakala, Lavanya Mahadevan, Neema Skariah, Venkata Giri Kavuru, Damodara Kuntrapaku, Suchitra Sajja, Mohammad Zainuddin, Krishnakumar V, Ritu Singh, Swarnakumari V, Ramachandraiah Gosu, Jayashree Aiyar, Pravin Iyer, Sriram Rajagopal
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3509.
https://doi.org/10.1158/1538-7445.AM2015-3509
Published: 01 August 2015
View articletitled, Abstract 3509: Novel dual inhibitors of LSD1-HDAC for treatment of cancer