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Ralph R. Weichselbaum
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Journal Articles

Abstract 4585: Tumor lymphangiogenesis sensitizes melanomas to the immunological effects of radiotherapy but also disrupts the local lymphatic vasculature

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Anish Mukherjee, Nikolaos Mitrousis, Mari Stella Sasso, Margo MacDonald, Ainhoa Arina, Phillip Ang, Ariana Baginski, J. Emiliano G. Medellin, Ralph R. Weichselbaum, Melody A. Swartz
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4585.
https://doi.org/10.1158/1538-7445.AM2023-4585
Published: 04 April 2023
View articletitled, Abstract 4585: Tumor lymphangiogenesis sensitizes melanomas to the immunological effects of radiotherapy but also disrupts the local lymphatic vasculature
Journal Articles

(Oligo)metastasis as a Spectrum of Disease

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Stanley I. Gutiontov, Sean P. Pitroda, Phuoc T. Tran, Ralph R. Weichselbaum
Journal: Cancer Research
Cancer Res (2021) 81 (10): 2577–2583.
https://doi.org/10.1158/0008-5472.CAN-20-3337
Published: 15 May 2021
View articletitled, (Oligo)metastasis as a Spectrum of Disease
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Journal Articles

RIG-I–Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy

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Wenxin Zheng, Diana Rose E. Ranoa, Xiaona Huang, Yuzhu Hou, Kaiting Yang, Elizabeth C. Poli, Michael A. Beckett, Yang-Xin Fu, Ralph R. Weichselbaum
Journal: Cancer Research
Cancer Res (2020) 80 (24): 5633–5641.
https://doi.org/10.1158/0008-5472.CAN-20-2324
Published: 15 December 2020
View articletitled, RIG-I–Like Receptor LGP2 Is Required for Tumor Control by Radiotherapy
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Includes: Supplementary data
Journal Articles

Abstract 2253: Lymphangiogenesis augments the anti-tumor efficacy of radiotherapy in mouse melanoma

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Nikolaos Mitrousis, Maria Stella Sasso, Ralph R. Weichselbaum, Jeffrey A. Hubbell, Melody A. Swartz
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2253.
https://doi.org/10.1158/1538-7445.AM2020-2253
Published: 15 August 2020
View articletitled, Abstract 2253: Lymphangiogenesis augments the anti-tumor efficacy of radiotherapy in mouse melanoma
Journal Articles

Abstract 2773: Increased tumor control boosting hypoxic regions identified with EPR pO2 imaging in 2 tumor types

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Howard Halpern, Matthew Maggio, Eugene Barth, Darwin Bodero, Richard C. Miller, Charles A. Pelizzari, Martyna Krzykawska-Serda, Subramanian V. Sundramoorthy, Bulent Aydogan, Ralph R. Weichselbaum, Victor M. Tormyshev, Inna Gertsenshteyn, Boris Epel
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2773.
https://doi.org/10.1158/1538-7445.AM2020-2773
Published: 15 August 2020
View articletitled, Abstract 2773: Increased tumor control boosting hypoxic regions identified with EPR pO2 imaging in 2 tumor types
Journal Articles

STING (or SRC) Like an ICB: Priming the Immune Response in Pancreatic Cancer

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Stanley I. Gutiontov, Ralph R. Weichselbaum
Journal: Cancer Research
Cancer Res (2019) 79 (15): 3815–3817.
https://doi.org/10.1158/0008-5472.CAN-19-1700
Published: 01 August 2019
View articletitled, STING (or SRC) Like an ICB: Priming the Immune Response in Pancreatic Cancer
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Journal Articles

Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma

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David J. Voce, Giovanna M. Bernal, Longtao Wu, Clayton D. Crawley, Wei Zhang, Nassir M. Mansour, Kirk E. Cahill, Szymon J. Szymura, Abhineet Uppal, David R. Raleigh, Ruben Spretz, Luis Nunez, Gustavo Larsen, Nikolai N. Khodarev, Ralph R. Weichselbaum, Bakhtiar Yamini
Journal: Cancer Research
Cancer Res (2019) 79 (10): 2536–2548.
https://doi.org/10.1158/0008-5472.CAN-18-2170
Published: 15 May 2019
View articletitled, Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma
Open the PDF for Temozolomide Treatment Induces lncRNA MALAT1 in an NF-κB and p53 Codependent Manner in Glioblastoma in another window
Includes: Supplementary data
Journal Articles

STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability

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Diana Rose E. Ranoa, Ryan C. Widau, Stephen Mallon, Akash D. Parekh, Claudia M. Nicolae, Xiaona Huang, Michael J. Bolt, Ainhoa Arina, Renate Parry, Stephen J. Kron, George-Lucian Moldovan, Nikolai N. Khodarev, Ralph R. Weichselbaum
Journal: Cancer Research
Cancer Res (2019) 79 (7): 1465–1479.
https://doi.org/10.1158/0008-5472.CAN-18-1972
Published: 01 April 2019
View articletitled, STING Promotes Homeostasis via Regulation of Cell Proliferation and Chromosomal Stability
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Includes: Supplementary data
Journal Articles

DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs

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Go Oshima, Elizabeth C. Poli, Michael J. Bolt, Alexandre Chlenski, Martin Forde, Jessica M.S. Jutzy, Neha Biyani, Mitchell C. Posner, Sean P. Pitroda, Ralph R. Weichselbaum, Nikolai N. Khodarev
Journal: Cancer Research
Series: Author Choice
Cancer Res (2019) 79 (3): 650–662.
https://doi.org/10.1158/0008-5472.CAN-18-0692
Published: 01 February 2019
View articletitled, DNA Methylation Controls Metastasis-Suppressive 14q32-Encoded miRNAs
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Includes: Supplementary data
Journal Articles

Abstract 4157: Second tumor type showing hypoxia targeting with radiation improves tumor control in a mammal tumor model

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Howard J. Halpern, Boris Epel, Matthew C. Maggio, Martyna Krzykawska-Serda, Gage H. Redler, Richard C. Miller, Eugene D. Barth, Ralph R. Weichselbaum, Victor M. Tormyshev
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4157.
https://doi.org/10.1158/1538-7445.AM2018-4157
Published: 01 July 2018
View articletitled, Abstract 4157: Second tumor type showing hypoxia targeting with radiation improves tumor control in a mammal tumor model
Journal Articles

Abstract 4759: TP53 control of the survivin-mediated radio-adaptive response in human tumors

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Jeffrey S. Murley, Richard C. Miller, Ralph R. Weichselbaum, David J. Grdina
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4759.
https://doi.org/10.1158/1538-7445.AM2017-4759
Published: 01 July 2017
View articletitled, Abstract 4759: TP53 control of the survivin-mediated radio-adaptive response in human tumors
Journal Articles

Abstract 1874: First demonstration that hypoxia targeting with radiation improves tumor control in a mammal tumor model

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Howard J. Halpern, Boris Epe;, Matthew C. Maggio, Martyna Krzykawska-Serda, Gage H. Redler, Richard C. Miller, Eugene D. Barth, Ralph R. Weichselbaum
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1874.
https://doi.org/10.1158/1538-7445.AM2017-1874
Published: 01 July 2017
View articletitled, Abstract 1874: First demonstration that hypoxia targeting with radiation improves tumor control in a mammal tumor model
Journal Articles

Abstract 3043: Survivin-mediated radio-sensitization response in p53 mutant tumor cells

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David J. Grdina, Jeffrey S. Murley, Richard C. Miller, Ralph R. Weichselbaum, Alfred W. Rademaker, Gayle E. Woloschak, Jian Jian Li
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3043.
https://doi.org/10.1158/1538-7445.AM2016-3043
Published: 15 July 2016
View articletitled, Abstract 3043: Survivin-mediated radio-sensitization response in p53 mutant tumor cells
Journal Articles

Abstract LB-251: Radiotherapy sensitizes pancreatic cancer to immunotherapy by promoting T cell infiltration

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Wenxin Zheng, Kinga B. Skowron, Jukes P. Namm, Byron Burnette, Christian Fernandez, Ainhoa Arina, Hua Liang, Michael T. Spiotto, Mitchell C. Posner, Yang-Xin Fu, Ralph R. Weichselbaum
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-251.
https://doi.org/10.1158/1538-7445.AM2016-LB-251
Published: 15 July 2016
View articletitled, Abstract LB-251: Radiotherapy sensitizes pancreatic cancer to immunotherapy by promoting T cell infiltration
Journal Articles

Decoy Receptor DcR1 Is Induced in a p50/Bcl3–Dependent Manner and Attenuates the Efficacy of Temozolomide

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Nassir M. Mansour, Giovanna M. Bernal, Longtao Wu, Clayton D. Crawley, Kirk E. Cahill, David J. Voce, Irina V. Balyasnikova, Wei Zhang, Ruben Spretz, Luis Nunez, Gustavo F. Larsen, Ralph R. Weichselbaum, Bakhtiar Yamini
Journal: Cancer Research
Cancer Res (2015) 75 (10): 2039–2048.
https://doi.org/10.1158/0008-5472.CAN-14-2144
Published: 13 May 2015
View articletitled, Decoy Receptor DcR1 Is Induced in a p50/Bcl3–Dependent Manner and Attenuates the Efficacy of Temozolomide
Open the PDF for Decoy Receptor DcR1 Is Induced in a p50/Bcl3–Dependent Manner and Attenuates the Efficacy of Temozolomide in another window
Includes: Supplementary data
Journal Articles

Abstract 861: Survivin-mediated adaptive response: a risk factor for IGRT

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David J. Grdina, Jeffrey S. Murley, Richard C. Miller, Gayle E. Woloschak, Jian Jian Li, Ralph R. Weichselbaum
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 861.
https://doi.org/10.1158/1538-7445.AM2014-861
Published: 01 October 2014
View articletitled, Abstract 861: Survivin-mediated adaptive response: a risk factor for IGRT
Journal Articles

Abstract 2746: An evaluation of poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer

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Jana Heitmann, Paul Geeleher, Michaela Keck, Zhixiang Zuo, Arun Khattri, Susanne Tepper, Michael Beckett, Ralph R. Weichselbaum, Sebastian Fetscher, Everett E. Vokes, Tanguy Seiwert
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2746.
https://doi.org/10.1158/1538-7445.AM2014-2746
Published: 01 October 2014
View articletitled, Abstract 2746: An evaluation of poly (ADP-ribose) polymerase inhibitor efficacy in head and neck cancer
Journal Articles

The RAD51-Stimulatory Compound RS-1 Can Exploit the RAD51 Overexpression That Exists in Cancer Cells and Tumors

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Jennifer M. Mason, Hillary L. Logan, Brian Budke, Megan Wu, Michal Pawlowski, Ralph R. Weichselbaum, Alan P. Kozikowski, Douglas K. Bishop, Philip P. Connell
Journal: Cancer Research
Cancer Res (2014) 74 (13): 3546–3555.
https://doi.org/10.1158/0008-5472.CAN-13-3220
Published: 30 June 2014
View articletitled, The RAD51-Stimulatory Compound RS-1 Can Exploit the RAD51 Overexpression That Exists in Cancer Cells and Tumors
Open the PDF for The RAD51-Stimulatory Compound RS-1 Can Exploit the RAD51 Overexpression That Exists in Cancer Cells and Tumors in another window
Includes: Supplementary data
Journal Articles

EPR Oxygen Images Predict Tumor Control by a 50% Tumor Control Radiation Dose

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Martyna Elas, Jessica M. Magwood, Brandi Butler, Chanel Li, Rona Wardak, Rebekah DeVries, Eugene D. Barth, Boris Epel, Samuel Rubinstein, Charles A. Pelizzari, Ralph R. Weichselbaum, Howard J. Halpern
Journal: Cancer Research
Cancer Res (2013) 73 (17): 5328–5335.
https://doi.org/10.1158/0008-5472.CAN-13-0069
Published: 02 September 2013
View articletitled, EPR Oxygen Images Predict Tumor Control by a 50% Tumor Control Radiation Dose
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Includes: Supplementary data
Journal Articles

A Survivin-Associated Adaptive Response in Radiation Therapy

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David J. Grdina, Jeffrey S. Murley, Richard C. Miller, Helena J. Mauceri, Harold G. Sutton, Jian Jian Li, Gayle E. Woloschak, Ralph R. Weichselbaum
Journal: Cancer Research
Cancer Res (2013) 73 (14): 4418–4428.
https://doi.org/10.1158/0008-5472.CAN-12-4640
Published: 15 July 2013
View articletitled, A Survivin-Associated Adaptive Response in Radiation Therapy
Open the PDF for A Survivin-Associated Adaptive Response in Radiation Therapy in another window
Includes: Supplementary data