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Ralph B. Arlinghaus
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Journal Articles

Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment

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Sobeyda B. Gomez-Chou, Agnieszka Katarzyna Swidnicka-Siergiejko, Niharika Badi, Myrriah Chavez-Tomar, Gregory B. Lesinski, Tanios Bekaii-Saab, Matthew R. Farren, Thomas A. Mace, Carl Schmidt, Yan Liu, Defeng Deng, Rosa F. Hwang, Liran Zhou, Todd Moore, Deyali Chatterjee, Huamin Wang, Xiaohong Leng, Ralph B. Arlinghaus, Craig D. Logsdon, Zobeida Cruz-Monserrate
Journal: Cancer Research
Cancer Res (2017) 77 (10): 2647–2660.
https://doi.org/10.1158/0008-5472.CAN-16-1986
Published: 14 May 2017
View articletitled, Lipocalin-2 Promotes Pancreatic Ductal Adenocarcinoma by Regulating Inflammation in the Tumor Microenvironment
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Includes: Supplementary data
Journal Articles

Abstract 2007: Differential roles of BCL-XL and BCL-2 in protecting mitochondria against oxidative stress in CML cells

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Hui Zhang, Weiqin Lu, Terrence Liu, Gang Chen, Zhao Chen, Dunyaporn Trachootham, Ralph B. Arlinghaus, Peng Huang
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2007.
https://doi.org/10.1158/1538-7445.AM2012-2007
Published: 15 April 2012
View articletitled, Abstract 2007: Differential roles of BCL-XL and BCL-2 in protecting mitochondria against oxidative stress in CML cells
Journal Articles

Inhibition of Lipocalin 2 Impairs Breast Tumorigenesis and Metastasis

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Xiaohong Leng, Tian Ding, Hui Lin, Yan Wang, Limei Hu, Jianhua Hu, Barry Feig, Wei Zhang, Lajos Pusztai, W. Fraser Symmans, Yun Wu, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2009) 69 (22): 8579–8584.
https://doi.org/10.1158/0008-5472.CAN-09-1934
Published: 11 November 2009
View articletitled, Inhibition of Lipocalin 2 Impairs Breast Tumorigenesis and Metastasis
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Includes: Supplementary data
Journal Articles

Janus Kinase 2: A Critical Target in Chronic Myelogenous Leukemia

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Ajoy K. Samanta, Hui Lin, Tong Sun, Hagop Kantarjian, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2006) 66 (13): 6468–6472.
https://doi.org/10.1158/0008-5472.CAN-06-0025
Published: 03 July 2006
View articletitled, Janus Kinase 2: A Critical Target in Chronic Myelogenous Leukemia
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Includes: Supplementary data
Journal Articles

SOX4 gene expression in human leukemic and benign hematopoietic cells

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Xiaoping Sun, Enze Wang, Daniel M. Jones, Haifa Shen, Marcella M. Johnson, Jean-Pierre J. Issa, Hesham Amin, Cheryl F. Ginsberg, Hagop M. Kantarjian, Michael Andreeff, Steven M. Kornblau, Armand B. Glassman, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 714.
Published: 15 April 2006
View articletitled, SOX4 gene expression in human leukemic and benign hematopoietic cells
Journal Articles

Bcr expression inhibits tumor formation induced by the Bcr-Abl oncoprotein but not cell proliferation

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Bastianella Perrazona, Hui Lin, Tong Sun, Yan Wang, Xiaoyang Ling, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 708.
Published: 15 April 2006
View articletitled, Bcr expression inhibits tumor formation induced by the Bcr-Abl oncoprotein but not cell proliferation
Journal Articles

Bcr-Abl expression induces redox imbalance with a preferential increase in hydrogen peroxide

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Hui Zhang, Geetha Achanta, Li Feng, Ralph B. Arlinghaus, Peng Huang
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 89.
Published: 15 April 2006
View articletitled, Bcr-Abl expression induces redox imbalance with a preferential increase in hydrogen peroxide
Journal Articles

Transplantation of splenic T-cells from mice vaccinated with lethally-irradiated leukemia cells expressing cell surface GM-CSF prevents leukemia.

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Xiaoyang Ling, Yan Wang, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1308.
Published: 15 April 2006
View articletitled, Transplantation of splenic T-cells from mice vaccinated with lethally-irradiated leukemia cells expressing cell surface GM-CSF prevents leukemia.
Journal Articles

Bcr-Abl regulates c-Myc expression in chronic myelogenous leukemia through a Bcr-Abl/Jak2 network of proteins involving Gab2, PI-3 kinase, NF-κB and GSK3β

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Ajoy K. Samanta, Hui Lin, Tong Sun, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 968.
Published: 15 April 2006
View articletitled, Bcr-Abl regulates c-Myc expression in chronic myelogenous leukemia through a Bcr-Abl/Jak2 network of proteins involving Gab2, PI-3 kinase, NF-κB and GSK3β
Journal Articles

Activated c-Abl in FUS1 haploinsufficient non-small cell lung carcinoma

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Jacki Lin, Tong Sun, Lin Ji, Jack Roth, John Minna, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 676.
Published: 01 May 2005
View articletitled, Activated c-Abl in FUS1 haploinsufficient non-small cell lung carcinoma
Journal Articles

Knockdown of STAT3 expression by RNAi inhibits the induction of breast tumors in immunocompetent mice

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Xiaoyang Ling, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1438.
Published: 01 May 2005
View articletitled, Knockdown of STAT3 expression by RNAi inhibits the induction of breast tumors in immunocompetent mice
Journal Articles

Knockdown of STAT3 Expression by RNA Interference Inhibits the Induction of Breast Tumors in Immunocompetent Mice

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Xiaoyang Ling, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2005) 65 (7): 2532–2536.
https://doi.org/10.1158/0008-5472.CAN-04-2425
Published: 01 April 2005
View articletitled, Knockdown of STAT3 Expression by RNA Interference Inhibits the Induction of Breast Tumors in Immunocompetent Mice
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Journal Articles

Vaccination with BCR-ABL positive hematopoietic cells expressing membrane-bound GM-CSF protects mice from developing leukemia

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Ralph B. Arlinghaus, Xiaoyang Ling
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1263.
Published: 01 April 2004
View articletitled, Vaccination with BCR-ABL positive hematopoietic cells expressing membrane-bound GM-CSF protects mice from developing leukemia
Journal Articles

Alternative Splicing Disrupts a Nuclear Localization Signal in Spleen Tyrosine Kinase That Is Required for Invasion Suppression in Breast Cancer

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Lei Wang, Lindsay Duke, Peter S. Zhang, Ralph B. Arlinghaus, W. Fraser Symmans, Aysegul Sahin, Richard Mendez, Jia Le Dai
Journal: Cancer Research
Cancer Res (2003) 63 (15): 4724–4730.
Published: 07 August 2003
View articletitled, Alternative Splicing Disrupts a Nuclear Localization Signal in Spleen Tyrosine Kinase That Is Required for Invasion Suppression in Breast Cancer
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Journal Articles

Bcr and Abl Interaction: Oncogenic Activation of c-Abl by Sequestering Bcr

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Xiaoyang Ling, Guozhen Ma, Tong Sun, Jiaxin Liu, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2003) 63 (2): 298–303.
Published: 15 January 2003
View articletitled, Bcr and Abl Interaction: Oncogenic Activation of c-Abl by Sequestering Bcr
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Journal Articles

Inhibition of the Bcr-Abl Oncoprotein by Bcr Requires Phosphoserine 354

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Natalyn Hawk, Tong Sun, Shanhai Xie, Yan Wang, Yun Wu, Jiaxin Liu, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2002) 62 (2): 386–390.
Published: 01 January 2002
View articletitled, Inhibition of the Bcr-Abl Oncoprotein by Bcr Requires Phosphoserine 354
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Journal Articles

Expression of a Truncated First Exon BCR Sequence in Chronic Myelogenous Leukemia Cells Blocks Cell Growth and Induces Cell Death

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Yan Wang, Jiaxin Liu, Yun Wu, Weiping Luo, Sue-Hwa Lin, Hui Lin, Natalyn Hawk, Tong Sun, Jie Qiang Guo, Zeev Estrov, Moshe Talpaz, Richard Champlin, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (2001) 61 (1): 138–144.
Published: 01 January 2001
View articletitled, Expression of a Truncated First Exon BCR Sequence in Chronic Myelogenous Leukemia Cells Blocks Cell Growth and Induces Cell Death
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Journal Articles

Sequences within the First Exon of BCR Inhibit the Activated Tyrosine Kinases of c-Abl and the Bcr-Abl Oncoprotein

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Jiaxin Liu, Yun Wu, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (1996) 56 (22): 5120–5124.
Published: 01 November 1996
View articletitled, Sequences within the First Exon of BCR Inhibit the Activated Tyrosine Kinases of c-Abl and the Bcr-Abl Oncoprotein
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Journal Articles

P210 Bcr-Abl Interacts with the Interleukin 3 Receptor βc Subunit and Constitutively Induces Its Tyrosine Phosphorylation

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Jeanne Wilson-Rawls, Shanhai Xie, Jiaxin Liu, Pierre Laneuville, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (1996) 56 (15): 3426–3430.
Published: 01 August 1996
View articletitled, P210 Bcr-Abl Interacts with the Interleukin 3 Receptor βc Subunit and Constitutively Induces Its Tyrosine Phosphorylation
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Journal Articles

Detection of BCR-ABL Proteins in Blood Cells of Benign Phase Chronic Myelogenous Leukemia Patients

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Jie Qiang Guo, Jean Y. J. Wang, Ralph B. Arlinghaus
Journal: Cancer Research
Cancer Res (1991) 51 (11): 3048–3051.
Published: 01 June 1991
View articletitled, Detection of BCR-ABL Proteins in Blood Cells of Benign Phase Chronic Myelogenous Leukemia Patients
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