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Journal Articles

Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance

Jianglan Liu, Vito W. Rebecca, Andrew V. Kossenkov, Thomas Connelly, Qin Liu, Alexis Gutierrez, Min Xiao, Ling Li, Gao Zhang, Anastasia Samarkina, Delaine Zayasbazan, Jie Zhang, Chaoran Cheng, Zhi Wei, Gretchen M. Alicea, Mizuho Fukunaga-Kalabis, Clemens Krepler, Pedro Aza-Blanc, Chih-Cheng Yang, Bela Delvadia, Cynthia Tong, Ye Huang, Maya Delvadia, Alice S. Morias, Katrin Sproesser, Patricia Brafford, Joshua X. Wang, Marilda Beqiri, Rajasekharan Somasundaram, Adina Vultur, Denitsa M. Hristova, Lawrence W. Wu, Yiling Lu, Gordon B. Mills, Wei Xu, Giorgos C. Karakousis, Xiaowei Xu, Lynn M. Schuchter, Tara C. Mitchell, Ravi K. Amaravadi, Lawrence N. Kwong, Dennie T. Frederick, Genevieve M. Boland, Joseph M. Salvino, David W. Speicher, Keith T. Flaherty, Ze'ev A. Ronai, Meenhard Herlyn
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5230–5241.
https://doi.org/10.1158/0008-5472.CAN-20-1496
Published: 15 October 2021
View article titled, Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance
Open the PDF for Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance in another window
Includes: Supplementary data
Journal Articles

Abstract A26: Humanized mouse model: A model to understand mechanisms of immune non-responsiveness to immune checkpoint inhibitors in melanoma

Rajasekharan Somasundaram, Anastasia Samarkina, Thomas Connelly, Robin Choi, Hedy Choi, Kar Muthumani, Xiaowei Xu, Klaus Kaestner, Meenhard Herlyn
Journal: Cancer Research
Cancer Res (2020) 80 (19_Supplement): A26.
https://doi.org/10.1158/1538-7445.MEL2019-A26
Published: 02 October 2020
View article titled, Abstract A26: Humanized mouse model: A model to understand mechanisms of immune non-responsiveness to immune checkpoint inhibitors in melanoma
Journal Articles

Abstract 5833: Escape form adaptive drug tolerance through OGT and TET1 mediated H3K4me3 remodeling in MAPKi resistant melanoma

Dinoop Ravindran Menon, Heinz Hammerlindl, Abdullah Al Emran, Joachim Torrano, Sabrina Hammerlindl, Gao Zhang, Rajasekharan Somasundaram, Richard A. Sturm, Nikolas K. Haass, Keith Flaherty, Meenhard Herlyn, Helmut Schaider
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5833.
https://doi.org/10.1158/1538-7445.AM2018-5833
Published: 01 July 2018
View article titled, Abstract 5833: Escape form adaptive drug tolerance through OGT and TET1 mediated H3K4me3 remodeling in MAPKi resistant melanoma
Journal Articles

Abstract LB-350: IgG4 expressing B cells associate with poor survival in triple negative breast cancer

Nicole Flynn, Ugochukwu Amadi, Rajasekharan Somasundaram, Jennifer Sims-Mourtada
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-350.
https://doi.org/10.1158/1538-7445.AM2018-LB-350
Published: 01 July 2018
View article titled, Abstract LB-350: IgG4 expressing B cells associate with poor survival in triple negative breast cancer
Journal Articles

Abstract 650: B lymphocytes promote upregulation of an IL-1-NfkB dependent signaling and increase invasiveness of triple negative breast cancer

Nicole Flynn, Rajasekharan Somasundaram, Jennifer Sims-Mourtada
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 650.
https://doi.org/10.1158/1538-7445.AM2017-650
Published: 01 July 2017
View article titled, Abstract 650: B lymphocytes promote upregulation of an IL-1-NfkB dependent signaling and increase invasiveness of triple negative breast cancer
Journal Articles

Abstract 2684: An early innate stress response precedes acquired drug resistance in melanoma

Dinoop Ravindran Menon, Suman Das, Clemens Krepler, Adina Vultur, Gao Zhang, Nikolas Haass, Peter H. Soyer, Brian Gabrielli, Rajasekharan Somasundaram, Gerald Hoefler, Meenhard Herlyn, Helmut Schaider
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 2684.
https://doi.org/10.1158/1538-7445.AM2015-2684
Published: 01 August 2015
View article titled, Abstract 2684: An early innate stress response precedes acquired drug resistance in melanoma
Journal Articles

Abstract 420: The role of tumor microenvironment in therapy resistance and melanoma progression

Rajasekharan Somasundaram, Gao Zhang, Stephan N. Wagner, Mizuho Fukunaga-Kalabis1, Meenhard Herlyn
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 420.
https://doi.org/10.1158/1538-7445.AM2015-420
Published: 01 August 2015
View article titled, Abstract 420: The role of tumor microenvironment in therapy resistance and melanoma progression
Journal Articles

Shared MHC Class II–Dependent Melanoma Ribosomal Protein L8 Identified by Phage Display

Rolf K. Swoboda, Rajasekharan Somasundaram, Laura Caputo, Elizabeth M. Ochoa, Phyllis A. Gimotty, Francesco M. Marincola, Patricia Van Belle, Stephen Barth, David Elder, DuPont Guerry, Brian Czerniecki, Lynn Schuchter, Robert H. Vonderheide, Dorothee Herlyn
Journal: Cancer Research
Cancer Res (2007) 67 (8): 3555–3559.
https://doi.org/10.1158/0008-5472.CAN-06-2763
Published: 17 April 2007
View article titled, Shared MHC Class II–Dependent Melanoma Ribosomal Protein L8 Identified by Phage Display
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Journal Articles

Human Leukocyte Antigen-A2–Restricted CTL Responses to Mutated BRAF Peptides in Melanoma Patients

Rajasekharan Somasundaram, Rolf Swoboda, Laura Caputo, Laszlo Otvos, Barbara Weber, Patricia Volpe, Patricia van Belle, Susan Hotz, David E. Elder, Francesco M. Marincola, Lynn Schuchter, DuPont Guerry, Brian J. Czerniecki, Dorothee Herlyn
Journal: Cancer Research
Cancer Res (2006) 66 (6): 3287–3293.
https://doi.org/10.1158/0008-5472.CAN-05-1932
Published: 15 March 2006
View article titled, Human Leukocyte Antigen-A2–Restricted CTL Responses to Mutated BRAF Peptides in Melanoma Patients
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Journal Articles

Inhibition of Cytolytic T Lymphocyte Proliferation by Autologous CD4+/CD25+ Regulatory T Cells in a Colorectal Carcinoma Patient Is Mediated by Transforming Growth Factor-β

Rajasekharan Somasundaram, Lutz Jacob, Rolf Swoboda, Laura Caputo, Hong Song, Saroj Basak, Dimitri Monos, David Peritt, Francesco Marincola, Dewei Cai, Brigitte Birebent, Ellen Bloome, Jin Kim, Klara Berencsi, Michael Mastrangelo, Dorothee Herlyn
Journal: Cancer Research
Cancer Res (2002) 62 (18): 5267–5272.
Published: 15 September 2002
View article titled, Inhibition of Cytolytic T Lymphocyte Proliferation by Autologous CD4<sup>+</sup>/CD25<sup>+</sup> Regulatory T Cells in a Colorectal Carcinoma Patient Is Mediated by Transforming Growth Factor-β
Open the PDF for Inhibition of Cytolytic T Lymphocyte Proliferation by Autologous CD4<sup>+</sup>/CD25<sup>+</sup> Regulatory T Cells in a Colorectal Carcinoma Patient Is Mediated by Transforming Growth Factor-β in another window