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Rafael Rosell
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Journal Articles

Abstract 6497: Molecular characterization and drug sensitivity of a gastric FGFR2-TACC2 and a pancreatic KRAS p.G12C primary culture

Silvia Garcia-Roman, Ekaterina Meshoulam Nikolaeva, Juan José García Mosquera, Mónica Garzón Ibáñez, Ruth Roman, Sonia Rodríguez, Cristina Rodríguez, Clara Mayo de las Casas, Rafael Rosell, Miguel A. Molina-Vila, Cristina Aguado Esteban
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6497.
https://doi.org/10.1158/1538-7445.AM2024-6497
Published: 22 March 2024
View article titled, Abstract 6497: Molecular characterization and drug sensitivity of a gastric FGFR2-TACC2 and a pancreatic KRAS p.G12C primary culture
Journal Articles

Abstract 1032: Development of a plasma circRNA signature for the discrimination of malign lung nodules using the nCounter platform

Carlos Pedraz Valdunciel, Giovanna Casagrande, Elizabeth Martínez-Pérez, Ana Gimenez-Capitán, Joselyn Valarezo, Pablo Rubinstein, Andrés Aguilar-Hernández, Leticia Ferro-Leal, Cristina Marino-Buslje, Rui Reis, Rafael Rosell, Miguel Ángel Molina-Vila
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1032.
https://doi.org/10.1158/1538-7445.AM2023-1032
Published: 04 April 2023
View article titled, Abstract 1032: Development of a plasma circRNA signature for the discrimination of malign lung nodules using the nCounter platform
Journal Articles

Abstract 4039: RET overexpression is frequent in lung neuroendocrine tumors (NET) and associates with response to RET tyrosine kinase inhibitors (RET TKIs) in NET cell lines

Jaume Roca-Arias, Jordi Bertran-Alamillo, Ruth Román, Cristina Aguado, Laura López, Leticia Ferro-Leal, Beatriz Garcia-Pelaez, Rodrigo de Oliveira Cavagna, Silvia Teixeira, Rafael Rosell, Rui Manuel Reis, Miguel A. Molina-Vila, Ivana Sullivan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4039.
https://doi.org/10.1158/1538-7445.AM2023-4039
Published: 04 April 2023
View article titled, Abstract 4039: RET overexpression is frequent in lung neuroendocrine tumors (NET) and associates with response to RET tyrosine kinase inhibitors (RET TKIs) in NET cell lines
Journal Articles

Abstract 1424: Prospective validation of a mRNA signature in plasma for the diagnosis of early stage lung cancer

Ana María Giménez Capitán, Pablo Rubisntein, Andrés Aguilar-Hernández, María González-cao, Irene Moya, Santiago Viteri, Carlos Cabrera, Santiago Ramón y Cajal, Karina Loor, Mario Culebras, Irene Sansano, Federico Rubisntein, Joselyn Valarezo, Clara Mayo-de las-Casas, Carlos Pedraz, Joseph Beechem, Sarah Warren, Rafael Rosell, Miguel Ángel Molina-Vila
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1424.
https://doi.org/10.1158/1538-7445.AM2022-1424
Published: 15 June 2022
View article titled, Abstract 1424: Prospective validation of a mRNA signature in plasma for the diagnosis of early stage lung cancer
Journal Articles

Abstract 1610: Primary cultures from malignant pleural effusions and ascites for drug screening in personalized therapy

Cristina A. Aguado, Beatriz Garcia, Andrés Aguilar-Hernández, Alejandro Martínez-Bueno, Marta Vives-Usano, Florencia Garcia-Casabal, Ruth Román, Ekaterina Meshoulam, Erika Aldeguer, Nuria Jordana-Ariza, Juan José García-Mosquera, Carlos Cabrera, Santiago Viteri, Sonia Rodríguez, Laura Berrocal-Gómez, Pablo Rubinstein, Clara Mayo-de-las-Casas, Rafael Rosell, Miguel Ángel Molina-Vila
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1610.
https://doi.org/10.1158/1538-7445.AM2022-1610
Published: 15 June 2022
View article titled, Abstract 1610: Primary cultures from malignant pleural effusions and ascites for drug screening in personalized therapy
Journal Articles

Abstract 1106: Detection of MET alterations at the DNA, RNA and protein levels in NSCLC patients progressing on ALK and ROS1 targeted therapies

Núria Jordana-Ariza, Nadine Reischmann, Carlos Esparré, Ruth Román, Cristina Aguado-Esteban, Silvia García-Román, Christopher Stroh, Andrés Aguilar Aguilar, Rafael Rosell, Niki Karachaliou, Miguel A. Molina-Vila
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1106.
https://doi.org/10.1158/1538-7445.AM2022-1106
Published: 15 June 2022
View article titled, Abstract 1106: Detection of MET alterations at the DNA, RNA and protein levels in NSCLC patients progressing on ALK and ROS1 targeted therapies
Journal Articles

Abstract 338: Anti-EGF antibodies significantly improve the activity of BRAF and KRAS inhibitors in preclinical models

Silvia Garcia-Roman, Miguel A. Molina-Vila, Erik d'Hondt, Rafael Rosell
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 338.
https://doi.org/10.1158/1538-7445.AM2022-338
Published: 15 June 2022
View article titled, Abstract 338: Anti-EGF antibodies significantly improve the activity of BRAF and KRAS inhibitors in preclinical models
Journal Articles

Abstract 2642: BID expression levels determine cell fate upon AURKB inhibition

Jordi Bertrán-Alamillo, John Travers, Sara Talbot, Rebecca Whiteley, Ana Giménez-Capitán, Ruth Román, Sonia Rodríguez, Erika Aldeguer, Josep Castellví, Alejandro Martínez-Bueno, Andrea Martella, Jamal Saeh, Giulia Fabbri, Rafael Rosell, Urszula Polanska, Jelena Urosevic, Miguel A. Molina-Vila
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2642.
https://doi.org/10.1158/1538-7445.AM2022-2642
Published: 15 June 2022
View article titled, Abstract 2642: BID expression levels determine cell fate upon AURKB inhibition
Journal Articles

Abstract 951: Evolution of antibody titers, growth factor levels and in vitro activity in the sera of patients enrolled in the EPICAL trial of afatinib combined with anti-EGF vaccination

Silvia Garcia-Roman, Jordi Codony, Miguel Angel Molina-Vila, Nuria Jordana-Ariza, Beatriz Garcia, Monica Garzon, Clara Mayo de las Casas, Maria Jose Catalan, Andres Aguilar, Santiago Viteri, Andres F. Cardona, Delvys Rodríguez, Manuel Cobo, Noemi Reguart, Erik d'Hondt, Rafael Rosell
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 951.
https://doi.org/10.1158/1538-7445.AM2021-951
Published: 01 July 2021
View article titled, Abstract 951: Evolution of antibody titers, growth factor levels and <em>in vitro</em> activity in the sera of patients enrolled in the EPICAL trial of afatinib combined with anti-EGF vaccination
Journal Articles

Abstract 409: A pre-treatment plasma extracellular vesicle-mRNA signature associates with checkpoint inhibitor pneumonitis in lung cancer patients

Jillian Wilhelmina Bracht, Santiago Viteri-Ramirez, Andrés Aguilar, Silvia Calabuig-Fariñas, Juan José García-Mosquera, Chung-Ying Huang, Elena Duréndez-Sáez, Nicolas Potie, Erika Aldeguer, Ana Gimenez-Capitán, Sonia Rodriguez, Ruth Roman, Cristina Aguado, Sarah Warren, Carlos Camps, Rafael Rosell, Eloisa Jantus-Lewintre, Miguel-Angel Molina-Vila, Maria González-Cao
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 409.
https://doi.org/10.1158/1538-7445.AM2021-409
Published: 01 July 2021
View article titled, Abstract 409: A pre-treatment plasma extracellular vesicle-mRNA signature associates with checkpoint inhibitor pneumonitis in lung cancer patients
Journal Articles

Abstract 469: Comprehensive, large scale analysis of ALK, ROS1, RET, NTRK1 and NRG1 transcripts in lung cancer reveals over-expressing, potentially targetable patients

Cristina Aguado, Cristina Teixido, Ana Gimenez Capitan, Elba Marin, Ruth Roman, Sonia Rodriguez, Irene Moya, Roxana Reyes, Nuria Viñolas, Santiago Viteri, Andres Aguilar, Rafael Rosell, Noemi Reguart, Miguel Angel Molina-Vila
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 469.
https://doi.org/10.1158/1538-7445.AM2021-469
Published: 01 July 2021
View article titled, Abstract 469: Comprehensive, large scale analysis of ALK, ROS1, RET, NTRK1 and NRG1 transcripts in lung cancer reveals over-expressing, potentially targetable patients
Journal Articles

Abstract 466: Differential expression of circRNAs allows discrimination of NSCLC from cancer-free lung specimens using the nCounter platform

Carlos Pedraz-Valdunciel, Miguel Ángel Molina-Vila, Stavros Giannoukakos, Nicolas Potie, Ruth Roman-Llado, Jill Bracht, Martyna Filipska, Masaoki Ito, Ana Gimenez-Capitán, Cristina Aguado-Esteban, Sarah Warren, Chung-Ying Huang, Trever Bivona, Rafael Rosell
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 466.
https://doi.org/10.1158/1538-7445.AM2021-466
Published: 01 July 2021
View article titled, Abstract 466: Differential expression of circRNAs allows discrimination of NSCLC from cancer-free lung specimens using the nCounter platform
Journal Articles

Abstract 2606: A nCounter-Based mRNA signature in plasma associates with localized non-small cell lung cancer

Ana Giménez Capitán, Jillian Bracht, Nicolas Potie, María González-Cao, Santiago Viteri, Alejandro Martínez-Bueno, Carlos Cabrera-Gálvez, Pablo Rubinstein, Clara Mayo-de-las-Casas, Joselyn Valarezo, Chung-Ying Huang, Carlos Pedraz, Richard Boykind, Sarah Warren, Rafael Rosell, Miguel Ángel Molina-Vilaa, Andrés Aguilar-Hernández
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2606.
https://doi.org/10.1158/1538-7445.AM2021-2606
Published: 01 July 2021
View article titled, Abstract 2606: A nCounter-Based mRNA signature in plasma associates with localized non-small cell lung cancer
Journal Articles

Abstract 1839: Nanobodies against EGF enhance the antitumoral effect of osimertinib and overcome resistance in non-small cell lung cancer cell models

Salvador Guardiola, Macarena Sánchez-Navarro, Ernest Giralt, Rafael Rosell, Jordi Codony-Servat
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1839.
https://doi.org/10.1158/1538-7445.AM2021-1839
Published: 01 July 2021
View article titled, Abstract 1839: Nanobodies against EGF enhance the antitumoral effect of osimertinib and overcome resistance in non-small cell lung cancer cell models
Journal Articles

Abstract 1020: Amplification of 22q11 is associated with hypersensitivity to AURKB inhibition in cell line models of resistance to EGFR TKIs

Jordi Bertran-Alamillo, Jon Travers, Ana Giménez-Capitán, Nicolas Floch, Ruth Román, Aisha Swaih, Sonia Rodríguez, Matthew Martin, Erika Aldeguer, Ricardo Miragaia, Josep Castellví, Paul Smith, Alejandro Martínez-Bueno, Elizabeth Pease, Henrik Ditzel, Giulia Fabbri, Rafael Rosell, Urszula Polanska, Miguel A Molina-Vila, Jelena Urosevic
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1020.
https://doi.org/10.1158/1538-7445.AM2021-1020
Published: 01 July 2021
View article titled, Abstract 1020: Amplification of 22q11 is associated with hypersensitivity to AURKB inhibition in cell line models of resistance to EGFR TKIs
Journal Articles

Abstract 290: Comparison of clinically relevant fusions detection using two multiplexing RNA based platforms: nCounter and GeneReader

Mónica Garzón Ibañez, Ana Gimenez-Capitán, Marta Vives Usano, Ruth Román Lladó, Sonia Rodriguez, Erika Aldeguer, Beatriz García Pelaez, Nuria Jordana Ariza, Cristina Aguado, Santiago Viteri, Andrés Aguilar, Irene Moya, Carlos Cabrera, Maria Jose Catalán, Maria Gonzalez cao, Silvia Garcia-Roman, Jordi Bertran Alamillo, Florencia Garcia Casabal, Rafael Rosell, Miguel Angel Molina-Vila, Clara De La Caridad Mayo De Las Casas
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 290.
https://doi.org/10.1158/1538-7445.AM2021-290
Published: 01 July 2021
View article titled, Abstract 290: Comparison of clinically relevant fusions detection using two multiplexing RNA based platforms: nCounter and GeneReader
Journal Articles

Abstract CT255: EATON: A phase I dose-escalation trial of nazartinib (EGF816) and trametinib in EGFR-mutant NSCLC

Sebastian Michels, Lucia Nogova, Matthias Scheffler, Barbara Deschler-Baier, Martin Sebastian, Martin Schuler, Martin Wermke, Enriqueta Felip, Rafael Rosell, Delvys Rodriguez Abreu, Diana S.Y. Abdulla, Rieke N. Fischer, Sophia Koleczko, Anna Kron, Richard Riedel, Jan-Philipp Weber, Jana Fassunke, Sabine Merkelbach-Bruse, Heinz Haverkammp, Martin Hellmich, Reinhard Büttner, Jürgen Wolf, Lung Cancer Group Cologne (LCGC) and Network Genomic Medicine (NGM)
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT255.
https://doi.org/10.1158/1538-7445.AM2020-CT255
Published: 15 August 2020
View article titled, Abstract CT255: EATON: A phase I dose-escalation trial of nazartinib (EGF816) and trametinib in EGFR-mutant NSCLC
Journal Articles

Abstract 3175: Copy number gains of clinically relevant genes in advanced non small cell lung cancer patients

Núria Jordana- Ariza, Mónica Garzón, Beatriz García-Peláez, Ruth Román, Jordi Bertrán- Alamillo, Sonia Rodriguez, Erika Aldeguer, Silvia García-Román, Santiago Viteri, Andrés Aguilar, María González Cao, Alejandro Martínez- Bueno, Miguel Angel Molina Vila, Rafael Rosell Costa, Clara Mayo de las Casas
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 3175.
https://doi.org/10.1158/1538-7445.AM2020-3175
Published: 15 August 2020
View article titled, Abstract 3175: Copy number gains of clinically relevant genes in advanced non small cell lung cancer patients
Journal Articles

Abstract 4294: An integrative project for tracing the genes involved in depression and cancer (DeCa) in peripheral blood

Carlos Pedraz, Jillian Wilhelmina Paulina Bracht, Martyna Filipska, Andrés Aguilar, Juan José García, Carlos Cabrera, María González Cao, Santiago Viteri, Imane Chaib, Manuel Fernández-Bruno, Rafael Rosell
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 4294.
https://doi.org/10.1158/1538-7445.AM2020-4294
Published: 15 August 2020
View article titled, Abstract 4294: An integrative project for tracing the genes involved in depression and cancer (DeCa) in peripheral blood
Journal Articles

Abstract 5594: Inmune gene expression by nCounter in mucinous adenocarcinoma lung cancer

Ruth Román Lladó, Cristina Aguado Esteban, Ana Giménez-Capitán, Ueda Daisuke, Masaoki Ito, Yasuhiro Tsutani, Yoshihiro Miyata, Cristina Teixidó, Noemí Reguart, Morihito Okada, Sonia Rodríguez, Ariadna Balada, Erika Aldeguer, Santiago Viteri Ramirez, Maria Gonzalez Cao, Andrés Aguilar, Rafael Rosell, Miguel Angel Molina Vila
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5594.
https://doi.org/10.1158/1538-7445.AM2020-5594
Published: 15 August 2020
View article titled, Abstract 5594: Inmune gene expression by nCounter in mucinous adenocarcinoma lung cancer