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Radoslaw Polanski
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Journal Articles

The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER+ Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance

Mandy Lawson, Natalie Cureton, Susana Ros, Azadeh Cheraghchi-Bashi, Jelena Urosevic, Sophie D'Arcy, Oona Delpuech, Michelle DuPont, David I. Fisher, Eric T. Gangl, Hilary Lewis, Dawn Trueman, Neha Wali, Stuart C. Williamson, Jennifer Moss, Elodie Montaudon, Heloise Derrien, Elisabetta Marangoni, Ricardo J. Miragaia, Sladjana Gagrica, Pablo Morentin-Gutierrez, Thomas A. Moss, Gareth Maglennon, Daniel Sutton, Radoslaw Polanski, Alan Rosen, Jonathan Cairns, Pei Zhang, Mònica Sánchez-Guixé, Violeta Serra, Susan E. Critchlow, James S. Scott, Justin P.O. Lindemann, Simon T. Barry, Teresa Klinowska, Christopher J. Morrow, Larissa S. Carnevalli
Journal: Cancer Research
Cancer Res (2023) 83 (23): 3989–4004.
https://doi.org/10.1158/0008-5472.CAN-23-0694
Published: 01 December 2023
View article titled, The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER<sup>+</sup> Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance
Open the PDF for The Next-Generation Oral Selective Estrogen Receptor Degrader Camizestrant (AZD9833) Suppresses ER<sup>+</sup> Breast Cancer Growth and Overcomes Endocrine and CDK4/6 Inhibitor Resistance in another window
Includes: Supplementary data
Journal Articles

Abstract 5674: Discovery of AZD9833, an oral small molecule selective degrader of the estrogen receptor (SERD)

James S. Scott, Thomas Moss, Steve Stokes, Willem M. Nissink, Christopher J. Morrow, Mandy Lawson, Natalie Cureton, Eric Gangl, Pablo Morentin Gutierrez, Richard Mather, Justin P. Lindemann, Andrew Sykes, David Fisher, Radoslaw Polanski, Danielle Carroll, Aisling Barton Twomey, Teresa Klinowska
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 5674.
https://doi.org/10.1158/1538-7445.AM2020-5674
Published: 15 August 2020
View article titled, Abstract 5674: Discovery of AZD9833, an oral small molecule selective degrader of the estrogen receptor (SERD)
Journal Articles

Abstract 3813: TRAIL and IAP inhibitor AZD5582 combination treatment induces profound tumor cell death, which is differentially dependent on the mitochondrial apoptotic pathway

Radoslaw Polanski, John Vincent, Urszula Polanska, Eric Tang
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3813.
https://doi.org/10.1158/1538-7445.AM2015-3813
Published: 01 August 2015
View article titled, Abstract 3813: TRAIL and IAP inhibitor AZD5582 combination treatment induces profound tumor cell death, which is differentially dependent on the mitochondrial apoptotic pathway
Journal Articles

Abstract 3060: Circulating tumor cells from small cell lung cancer patients are tumorigenic

Christopher J. Morrow, Cassandra L. Hodgkinson, Yaoyong Li, Robert Metcalf, Dominic Rothwell, Francesca Trapani, Radoslaw Polanski, Debbie Burt, Kathryn Simpson, Karen Morris, Stuart Pepper, Daisuke Nonaka, Alastair Greystole, Paul Kelly, Matthew Krebs, Jenny Antonello, Mahmood Ayub, Suzanne Faulkner, Lynsey Priest, Louise Carter, Catriona Tate, Crispin J. Miller, Fiona Blackhall, Ged Brady, Caroline Dive
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3060.
https://doi.org/10.1158/1538-7445.AM2014-3060
Published: 01 October 2014
View article titled, Abstract 3060: Circulating tumor cells from small cell lung cancer patients are tumorigenic
Journal Articles

Abstract 5434: Inhibition of monocarboxylate transporter 1 as a therapeutic strategy in small cell lung cancer: target validation studies using the MCT1 inhibitor AZD3965.

Radoslaw Polanski, Cassandra L. Hodgkinson, Daisuke Nonaka, Lynsey Priest, Paul D. Smith, Fiona Blackhall, Christopher J. Morrow, Caroline Dive
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5434.
https://doi.org/10.1158/1538-7445.AM2013-5434
Published: 15 April 2013
View article titled, Abstract 5434: Inhibition of monocarboxylate transporter 1 as a therapeutic strategy in small cell lung cancer: target validation studies using the MCT1 inhibitor AZD3965.