1-20 of 23
Qing Chang
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

Open Access
Sunyana Gadal, Jacob A. Boyer, Simon F. Roy, Noah A. Outmezguine, Malvika Sharma, Hongyan Li, Ning Fan, Eric Chan, Yevgeniy Romin, Afsar Barlas, Qing Chang, Priya Pancholi, Neilawattie Merna Timaul, Michael Overholtzer, Rona Yaeger, Katia Manova-Todorova, Elisa de Stanchina, Marcus W. Bosenberg, Neal Rosen
Journal: Cancer Research
Cancer Res (2025) 85 (9): 1611–1627.
https://doi.org/10.1158/0008-5472.CAN-24-2220
Published: 02 May 2025
View articletitled, Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration
Open the PDF for Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 5655: preclinical development of a novel anti-tslpr bispecific antibody 1b7/cd3 targeting crlf2-rearranged ph-like b-all

Free
Ze Tian, chunhua shi, Amin AI-Shami, GuoJun Yong, Jason K Allen, Jill Wardell Olson, Melinda G Smith, Qing Chang, Qing Shi, Junping You, Michelle A Gonzalez, Timothy E Lofton, Jasbir Kaur, Qi Zhang, DongXing Zha, Nitin Jain, Marina Y Konopleva, Timothy Heffernan, Jeffrey J Molldrem
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5655.
https://doi.org/10.1158/1538-7445.AM2023-5655
Published: 04 April 2023
View articletitled, Abstract 5655: preclinical development of a novel anti-tslpr bispecific antibody 1b7/cd3 targeting crlf2-rearranged ph-like b-all
Journal Articles

Abstract 4007: Efficacy of vepafestinib in preclinical models of RET fusion-driven sarcoma models

Free
Igor Odintsov, Ryan C. Cheng, Allan J. Lui, Tom Zhang, Yue C. Lu, Renate I. Kurth, Morana Vojnic, Inna Khodos, Qing Chang, Kevin Chen, Claudio Giuliano, Annalisa Bonifacio, Isao Miyazaki, Elisa de Stanchina, Emanuela Lovati, Marc Ladanyi, Romel Somwar
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4007.
https://doi.org/10.1158/1538-7445.AM2023-4007
Published: 04 April 2023
View articletitled, Abstract 4007: Efficacy of vepafestinib in preclinical models of RET fusion-driven sarcoma models
Journal Articles

Abstract 87: Asparagine synthetase (ASNS) expression predicts response to the GLS1 inhibitor IPN60090 in ovarian cancer through selective modulation of redox homeostasis

Free
Nakia D. Spencer, Christopher A. Bristow, Virginia Giulani, Meredith A. Miller, Alessandro Carugo, Angela L. Harris, Rosalba Minelli, Ningpeng Feng, Qing Chang, Michael J. Soth, Kang Le, John N. Weinstein, Philip L. Lorenzi, Jinsong Liu, Wei-Lien Wang, Timothy A. Yap, Giulio Draetta, Philip Jones, Timothy P. Heffernan, Jeffrey J. Kovacs
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 87.
https://doi.org/10.1158/1538-7445.AM2021-87
Published: 01 July 2021
View articletitled, Abstract 87: Asparagine synthetase (ASNS) expression predicts response to the GLS1 inhibitor IPN60090 in ovarian cancer through selective modulation of redox homeostasis
Journal Articles

Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules

Free
Kamini Singh, Jianan Lin, Nicolas Lecomte, Prathibha Mohan, Askan Gokce, Viraj R. Sanghvi, Man Jiang, Olivera Grbovic-Huezo, Antonija Burčul, Stefan G. Stark, Paul B. Romesser, Qing Chang, Jerry P. Melchor, Rachel K. Beyer, Mark Duggan, Yoshiyuki Fukase, Guangli Yang, Ouathek Ouerfelli, Agnes Viale, Elisa de Stanchina, Andrew W. Stamford, Peter T. Meinke, Gunnar Rätsch, Steven D. Leach, Zhengqing Ouyang, Hans-Guido Wendel
Journal: Cancer Research
Series: Author Choice
Cancer Res (2021) 81 (8): 2002–2014.
https://doi.org/10.1158/0008-5472.CAN-20-2929
Published: 15 April 2021
View articletitled, Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules
Open the PDF for Targeting eIF4A-Dependent Translation of KRAS Signaling Molecules in another window
Includes: Supplementary data
Journal Articles

Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib

Free
Yuting Sun, Brooke A. Meyers, Barbara Czako, Paul Leonard, Faika Mseeh, Angela L. Harris, Qi Wu, Sarah Johnson, Connor A. Parker, Jason B. Cross, Maria Emilia Di Francesco, Benjamin J. Bivona, Christopher A. Bristow, Jason P. Burke, Caroline C. Carrillo, Christopher L. Carroll, Qing Chang, Ningping Feng, Guang Gao, Sonal Gera, Virginia Giuliani, Justin K. Huang, Yongying Jiang, Zhijun Kang, Jeffrey J. Kovacs, Chiu-Yi Liu, Anastasia M. Lopez, Xiaoyan Ma, Pijus K. Mandal, Timothy McAfoos, Meredith A. Miller, Robert A. Mullinax, Michael Peoples, Vandhana Ramamoorthy, Sahil Seth, Nakia D. Spencer, Erika Suzuki, Christopher C. Williams, Simon S. Yu, Andy M. Zuniga, Giulio F. Draetta, Joseph R. Marszalek, Timothy P. Heffernan, Nancy E. Kohl, Philip Jones
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (21): 4840–4853.
https://doi.org/10.1158/0008-5472.CAN-20-1634
Published: 03 November 2020
View articletitled, Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib
Open the PDF for Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib in another window
Includes: Supplementary data
Journal Articles

An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer

Free
Xin Lu, Xiaolu Pan, Chang-Jiun Wu, Di Zhao, Shan Feng, Yong Zang, Rumi Lee, Sunada Khadka, Samirkumar B. Amin, Eun-Jung Jin, Xiaoying Shang, Pingna Deng, Yanting Luo, William R. Morgenlander, Jacqueline Weinrich, Xuemin Lu, Shan Jiang, Qing Chang, Nora M. Navone, Patricia Troncoso, Ronald A. DePinho, Y. Alan Wang
Journal: Cancer Research
Cancer Res (2018) 78 (14): 3823–3833.
https://doi.org/10.1158/0008-5472.CAN-17-3564
Published: 15 July 2018
View articletitled, An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer
Open the PDF for An In Vivo Screen Identifies PYGO2 as a Driver for Metastatic Prostate Cancer in another window
Journal Articles

Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles

Free
Pasquale Sansone, Marjan Berishaj, Vinagolu K. Rajasekhar, Claudio Ceccarelli, Qing Chang, Antonio Strillacci, Claudia Savini, Lauren Shapiro, Robert L. Bowman, Chiara Mastroleo, Sabrina De Carolis, Laura Daly, Alberto Benito-Martin, Fabiana Perna, Nicola Fabbri, John H. Healey, Enzo Spisni, Monica Cricca, David Lyden, Massimiliano Bonafé, Jacqueline Bromberg
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (8): 1927–1941.
https://doi.org/10.1158/0008-5472.CAN-16-2129
Published: 13 April 2017
View articletitled, Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles
Open the PDF for Evolution of Cancer Stem-like Cells in Endocrine-Resistant Metastatic Breast Cancers Is Mediated by Stromal Microvesicles in another window
Includes: Supplementary data
Journal Articles

Abstract LB-236: Self-renewal of CD133hi cells by IL6/Notch3 signaling regulates endocrine resistance in metastatic breast cancers

Free
Pasquale Sansone, Ceccarelli Claudio, Marjan Berishaj, Qing Chang, Rajasekhar Vinagolu, Fabiana Perna, Robert Bowman, Michele Vidone, Laura Daly, Jennifer Nnoli, Donatella Santini, Taffurelli Mario, Natalie Shih, Michael Feldman, Jun James Mao, Christopher Colameco, Jinbo Chen, Angela DeMichele, Nicola Fabbri, John Healey, Monica Cricca, Giuseppe Gasparre, David Lyden, Massimiliano Bonafe, Jacqueline F. Bromberg
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): LB-236.
https://doi.org/10.1158/1538-7445.AM2016-LB-236
Published: 15 July 2016
View articletitled, Abstract LB-236: Self-renewal of CD133hi cells by IL6/Notch3 signaling regulates endocrine resistance in metastatic breast cancers
Journal Articles

Abstract A26: Targeting Wee1 in primary pancreatic cancer xenografts.

Free
Qing Chang, Jason Moffat, David W. Hedley
Journal: Cancer Research
Cancer Res (2012) 72 (14_Supplement): A26.
https://doi.org/10.1158/1538-7445.PANCA2012-A26
Published: 03 April 2014
View articletitled, Abstract A26: Targeting Wee1 in primary pancreatic cancer xenografts.
Journal Articles

Abstract 1514: The Warburg effect in stromal cells drives breast cancer cell plasticity via interleukin 6

Free
Pasquale Sansone, Claudio Ceccarelli, Gianluca Storci, Marjan Berishaj, Monica Cricca, Qing Chang, Donatella Santini, Massimiliano Bonafe, Jacqueline Bromberg
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1514.
https://doi.org/10.1158/1538-7445.AM2012-1514
Published: 15 April 2012
View articletitled, Abstract 1514: The Warburg effect in stromal cells drives breast cancer cell plasticity via interleukin 6
Journal Articles

Abstract 5253: A model of tumor dormancy in Luminal A breast cancer

Free
Pasquale Sansone, Lauren Shapiro, Qing Chang, Marjan Berishaj, Jaqueline Bromberg
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5253.
https://doi.org/10.1158/1538-7445.AM2011-5253
Published: 15 April 2011
View articletitled, Abstract 5253: A model of tumor dormancy in Luminal A breast cancer
Journal Articles

Hypoxia Predicts Aggressive Growth and Spontaneous Metastasis Formation from Orthotopically Grown Primary Xenografts of Human Pancreatic Cancer

Free
Qing Chang, Igor Jurisica, Trevor Do, David W. Hedley
Journal: Cancer Research
Cancer Res (2011) 71 (8): 3110–3120.
https://doi.org/10.1158/0008-5472.CAN-10-4049
Published: 13 April 2011
View articletitled, Hypoxia Predicts Aggressive Growth and Spontaneous Metastasis Formation from Orthotopically Grown Primary Xenografts of Human Pancreatic Cancer
Open the PDF for Hypoxia Predicts Aggressive Growth and Spontaneous Metastasis Formation from Orthotopically Grown Primary Xenografts of Human Pancreatic Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract #229: Relations between hypoxia, epithelial-mesenchymal transition markers, and tumor progression in human orthotopic primary pancreatic cancer xenografts

Free
Qing Chang, David Hedley, Trevor Do, Neesha Dhani, Joerg Schwock
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 229.
Published: 01 May 2009
View articletitled, Abstract #229: Relations between hypoxia, epithelial-mesenchymal transition markers, and tumor progression in human orthotopic primary pancreatic cancer xenografts
Journal Articles

Abstract #LB-151: Identification and in vitro characterization of a human monoclonal antibody against IGF-II

Free
Edward Cohen, Qing Chang, Timothy Adams, Leah Cosgrove, Lindsay Sparrow, John Bentley, Olan Dolezal, Xiaowen Xiao, Tom Peat, Janet Newman, Pat Pilling, Tram Phan, Gemma Brierley, Niksa Katrapeli, Kris Kopacz, Diana Martik, Dina Wassaf, Doug Rank, Greg Conley, Daniel Dransfield
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): LB-151.
Published: 01 May 2009
View articletitled, Abstract #LB-151: Identification and in vitro characterization of a human monoclonal antibody against IGF-II
Journal Articles

AP1G2b, an isoform of clathrin-coated adaptor protein, localizes in the nucleus and transactivates target gene estrogen receptor α

Free
Rui-An Wang, Qing-Chang Meng, Rakesh Kumar
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 223.
Published: 15 April 2006
View articletitled, AP1G2b, an isoform of clathrin-coated adaptor protein, localizes in the nucleus and transactivates target gene estrogen receptor α
Journal Articles

Enhanced inhibition of VEGF binding and activity by mixtures of neuropilin-1-binding and VEGFR-2-binding peptides

Free
Mathew A. Von Wronski, Nancy J. Bogdan, Ajay Shrivastava, Natarajan Raju, Radhakrishna Pillai, Edmund R. Marinelli, Aaron K. Sato, Robert C. Ladner, Daniel T. Dransfield, Daniel Sexton, Mary Devlin, Greg Conley, Qing Chang, Rolf E. Swenson, Michael F. Tweedle, Adrian D. Nunn
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 915.
Published: 01 May 2005
View articletitled, Enhanced inhibition of VEGF binding and activity by mixtures of neuropilin-1-binding and VEGFR-2-binding peptides
Journal Articles

A strategy to generate high affinity peptide binders to the external domains of receptor tyrosine kinases

Free
Ajay Shrivastava, Mathew A. Von Wronski, Aaron K. Sato, Daniel T. Dransfield, Daniel Sexton, Nancy J. Bogdan, Radhakrishna Pillai, Palaniappa Nanjappan, Bo Song, Edmund R. Marinelli, Daniel Deoliveira, Chris Luneau, Mary Devlin, Arumugam Muruganandam, Aida Abujoub, Gene Connelly, Qi-Long Wu, Greg Conley, Qing Chang, Michael F. Tweedle, Robert C. Ladner, Rolf E. Swenson, Adrian D. Nunn
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1060.
Published: 01 May 2005
View articletitled, A strategy to generate high affinity peptide binders to the external domains of receptor tyrosine kinases
Journal Articles

In vivo inhibition of VEGF-induced vascular permeability by a heterodimeric VEGFR-2-binding peptide

Free
Sudha Khurana, Mathew A. Von Wronski, Nancy J. Bogdan, Radhkrishna Pillai, Edmund R. Marinelli, Aaron K. Sato, Robert C. Ladner, Daniel T. Dransfield, Daniel Sexton, Mary Devlin, Greg Conley, Qing Chang, Rolf E. Swenson, Michael F. Tweedle, Adrian D. Nunn
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 909–910.
Published: 01 May 2005
View articletitled, In vivo inhibition of VEGF-induced vascular permeability by a heterodimeric VEGFR-2-binding peptide
Journal Articles

Genetic alterations of DLC1 in medulloblastoma and primitive neuroectodermal tumor

Free
Qing Chang, Jesse Chung-Sean Pang, Ho-Keung Ng
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 21.
Published: 01 April 2004
View articletitled, Genetic alterations of DLC1 in medulloblastoma and primitive neuroectodermal tumor