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Journal Articles

Abstract 8: Identifying the role of KIF20A in stemness and metastasis in hepatocellular carcinoma

Free
Liuxian Ban, Xiaona Fang, Shan Liu, Jie Luo, Lanqi Gong, Hongyu Zhou, Beilei Liu, Jiao Huang, Nanzhou Yu, Yingchen Lyu, Licheng Tan, Qin Liu, Cuicui Huang, Xin-Yuan Guan
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 8.
https://doi.org/10.1158/1538-7445.AM2025-8
Published: 21 April 2025
View articletitled, Abstract 8: Identifying the role of KIF20A in stemness and metastasis in hepatocellular carcinoma
Journal Articles

Abstract 5155: CD8+ T cells and CD4+central memory T cells as biomarkers of perioperative anti-PD-1 therapy in combination with concurrent chemoradiotherapy for locally advanced G/GEJ adenocarcinoma

Free
Yue Wang, Yawei Chen, Ju Yang, Xiaoyu Zhou, Yutao Wei, Qin Liu, Yang Yang, Wenxian Guan, Baorui Liu, Jia Wei
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5155.
https://doi.org/10.1158/1538-7445.AM2024-5155
Published: 22 March 2024
View articletitled, Abstract 5155: CD8+ T cells and CD4+central memory T cells as biomarkers of perioperative anti-PD-1 therapy in combination with concurrent chemoradiotherapy for locally advanced G/GEJ adenocarcinoma
Journal Articles

Abstract 5001: Personalized neoantigen/cancer-testis antigen nanovaccine for advanced solid tumors, a single-arm, open-label pilot study

Free
Jia Wei, Qin Liu, Lijing Zhu, Jie Shao, Ju Yang, Guanghui Xu, Nandie Wu, Hanbing Wang, Rutian Li, Huizi Sha, Qiuping Xu, Jie Shen, Li Xie, Lifeng Wang, Juan Du, Lanqi Cen, Manman Tian, Lixia Yu, Baorui Liu
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5001.
https://doi.org/10.1158/1538-7445.AM2024-5001
Published: 22 March 2024
View articletitled, Abstract 5001: Personalized neoantigen/cancer-testis antigen nanovaccine for advanced solid tumors, a single-arm, open-label pilot study
Journal Articles

Abstract 4263: Prostate cancer cell-derived small extracellular vesicles regulate monocyte migration via STEAP4 and promote a monocyte transitional state

Free
Nicole M. Naranjo, Anna Testa, Santosh K. Yadav, Ulhas P. Naik, Lei Yu, William K. Kelly, Qin Liu, Jianyi Ding, Hushan Yang, Hsin Yao Tang, Cecilia E. Verrillo, Craig D. Hooper, Lucia R. Languino
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4263.
https://doi.org/10.1158/1538-7445.AM2024-4263
Published: 22 March 2024
View articletitled, Abstract 4263: Prostate cancer cell-derived small extracellular vesicles regulate monocyte migration via STEAP4 and promote a monocyte transitional state
Journal Articles

Abstract 4450: SOX4 promotes tumor development and immune evasion via disruption of zinc homeostasis between nasopharyngeal carcinoma cells and T cells

Free
Yuma Yang, Lanqi Gong, Jie Luo, Xiaona Fang, Jiao Huang, Lu Bai, Qin Liu, Beilei Liu, Shan Liu, Jinlin Huang, Ching Ngar Wong, Baifeng Zhang, Danyang Zheng, Yu Zhang, Wei Dai, Xinyuan Guan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4450.
https://doi.org/10.1158/1538-7445.AM2023-4450
Published: 04 April 2023
View articletitled, Abstract 4450: SOX4 promotes tumor development and immune evasion via disruption of zinc homeostasis between nasopharyngeal carcinoma cells and T cells
Journal Articles

Abstract 4145: Frizzled-4 expression enhances hepatocellular carcinoma progression, sorafenib resistance and suppresses anti-tumor CD8 T cell immunity

Free
Jie Luo, Lanqi Gong, Yuma Yang, Qin Liu, Jiao Huang, Xiaona Fang, Xin-Yuan Guan
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4145.
https://doi.org/10.1158/1538-7445.AM2023-4145
Published: 04 April 2023
View articletitled, Abstract 4145: Frizzled-4 expression enhances hepatocellular carcinoma progression, sorafenib resistance and suppresses anti-tumor CD8 T cell immunity
Journal Articles

Abstract C023: A microbiome-produced metabolite drives immunostimulatory macrophages and boosts response to immune checkpoint inhibitors in pancreatic cancer

Free
Gauri Mirji, Alison Worth, Sajad Bhat, Mohamed Sayed, Toshitha Kannan, Aaron Goldman, Hsin-Yao Tang, Qin Liu, Noam Auslander, Chi Dang, Mohamed Abdel-Mohsen, Andrew Kossenkov, Ben Stanger, Rahul Shinde
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): C023.
https://doi.org/10.1158/1538-7445.PANCA22-C023
Published: 15 November 2022
View articletitled, Abstract C023: A microbiome-produced metabolite drives immunostimulatory macrophages and boosts response to immune checkpoint inhibitors in pancreatic cancer
Journal Articles

Abstract 6199: Fusion genes: Novel therapeutic targets for gastric signet ring cell carcinoma

Free
Yue Wang, Tao Shi, Xuan Wang, Jinwei Hu, Lixia Yu, Qin Liu, Nandie Wu, Baorui Liu, Jia Wei
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6199.
https://doi.org/10.1158/1538-7445.AM2022-6199
Published: 15 June 2022
View articletitled, Abstract 6199: Fusion genes: Novel therapeutic targets for gastric signet ring cell carcinoma
Journal Articles

Abstract 6176: CD56 dim+ immune infiltration and reprogrammed TMEs associated with response to neoadjuvant anti-PD-1 immunotherapy plus concurrent chemoradiotherapy in locally advanced gastric or gastroesophageal junction adenocarcinoma

Free
Jia Wei, Qin Liu, Hui Chen, Xin Zhang, Feilong Zhao, Yao Fu, Ju Yang, Yue Wang, Shiqing Chen, Xiaochen Zhao, Yuezong Bai, Wenxian Guan, Baorui Liu
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 6176.
https://doi.org/10.1158/1538-7445.AM2022-6176
Published: 15 June 2022
View articletitled, Abstract 6176: CD56 dim+ immune infiltration and reprogrammed TMEs associated with response to neoadjuvant anti-PD-1 immunotherapy plus concurrent chemoradiotherapy in locally advanced gastric or gastroesophageal junction adenocarcinoma
Journal Articles

Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers

Free
Joseph A. Zundell, Takeshi Fukumoto, Jianhuang Lin, Nail Fatkhudinov, Timothy Nacarelli, Andrew V. Kossenkov, Qin Liu, Joel Cassel, Chih-Chi Andrew Hu, Shuai Wu, Rugang Zhang
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5325–5335.
https://doi.org/10.1158/0008-5472.CAN-21-1545
Published: 15 October 2021
View articletitled, Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers
Open the PDF for Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers in another window
Includes: Supplementary data
Journal Articles

Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance

Open Access
Jianglan Liu, Vito W. Rebecca, Andrew V. Kossenkov, Thomas Connelly, Qin Liu, Alexis Gutierrez, Min Xiao, Ling Li, Gao Zhang, Anastasia Samarkina, Delaine Zayasbazan, Jie Zhang, Chaoran Cheng, Zhi Wei, Gretchen M. Alicea, Mizuho Fukunaga-Kalabis, Clemens Krepler, Pedro Aza-Blanc, Chih-Cheng Yang, Bela Delvadia, Cynthia Tong, Ye Huang, Maya Delvadia, Alice S. Morias, Katrin Sproesser, Patricia Brafford, Joshua X. Wang, Marilda Beqiri, Rajasekharan Somasundaram, Adina Vultur, Denitsa M. Hristova, Lawrence W. Wu, Yiling Lu, Gordon B. Mills, Wei Xu, Giorgos C. Karakousis, Xiaowei Xu, Lynn M. Schuchter, Tara C. Mitchell, Ravi K. Amaravadi, Lawrence N. Kwong, Dennie T. Frederick, Genevieve M. Boland, Joseph M. Salvino, David W. Speicher, Keith T. Flaherty, Ze'ev A. Ronai, Meenhard Herlyn
Journal: Cancer Research
Cancer Res (2021) 81 (20): 5230–5241.
https://doi.org/10.1158/0008-5472.CAN-20-1496
Published: 15 October 2021
View articletitled, Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance
Open the PDF for Neural Crest-Like Stem Cell Transcriptome Analysis Identifies LPAR1 in Melanoma Progression and Therapy Resistance in another window
Includes: Supplementary data
Journal Articles

Abstract 1718: Tumor eradicated by an effective in situ vaccine based on a TLR agonist and an agonistic anti-OX40 antibody

Free
Yanhong Chu, Qin Liu, Baorui Liu
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1718.
https://doi.org/10.1158/1538-7445.AM2021-1718
Published: 01 July 2021
View articletitled, Abstract 1718: Tumor eradicated by an effective in situ vaccine based on a TLR agonist and an agonistic anti-OX40 antibody
Journal Articles

Myeloid-Derived Suppressor Cells Are a Major Source of Wnt5A in the Melanoma Microenvironment and Depend on Wnt5A for Full Suppressive Activity

Available to Purchase
Stephen M. Douglass, Mitchell E. Fane, Emilio Sanseviero, Brett L. Ecker, Curtis H. Kugel, III, Reeti Behera, Vinit Kumar, Evgenii N. Tcyganov, Xiangfan Yin, Qin Liu, Yash Chhabra, Gretchen M. Alicea, Rejji Kuruvilla, Dmitry I. Gabrilovich, Ashani T. Weeraratna
Journal: Cancer Research
Cancer Res (2021) 81 (3): 658–670.
https://doi.org/10.1158/0008-5472.CAN-20-1238
Published: 01 February 2021
View articletitled, Myeloid-Derived Suppressor Cells Are a Major Source of Wnt5A in the Melanoma Microenvironment and Depend on Wnt5A for Full Suppressive Activity
Open the PDF for Myeloid-Derived Suppressor Cells Are a Major Source of Wnt5A in the Melanoma Microenvironment and Depend on Wnt5A for Full Suppressive Activity in another window
Includes: Supplementary data
Journal Articles

A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors

Available to Purchase
Thibaut Barnoud, Jessica C. Leung, Julia I-Ju Leu, Subhasree Basu, Adi Narayana Reddy Poli, Joshua L.D. Parris, Alexandra Indeglia, Tetyana Martynyuk, Madeline Good, Keerthana Gnanapradeepan, Emilio Sanseviero, Rebecca Moeller, Hsin-Yao Tang, Joel Cassel, Andrew V. Kossenkov, Qin Liu, David W. Speicher, Dmitry I. Gabrilovich, Joseph M. Salvino, Donna L. George, Maureen E. Murphy
Journal: Cancer Research
Cancer Res (2020) 80 (23): 5270–5281.
https://doi.org/10.1158/0008-5472.CAN-20-0397
Published: 02 December 2020
View articletitled, A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors
Open the PDF for A Novel Inhibitor of HSP70 Induces Mitochondrial Toxicity and Immune Cell Recruitment in Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract 1049: Personalized neoantigen/cancer testis antigen nanovaccine (PVAC) in combination with PD-1 monoclonal antibody and/or antiangiogenic treatment in patients with metastatic solid tumors

Free
Jia Wei, Qin Liu, Hanqing Qian, Jie Shao, Lijing Zhu, Lifeng Wang, Lixia Yu, Huizi Sha, Baorui Liu
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1049.
https://doi.org/10.1158/1538-7445.AM2020-1049
Published: 15 August 2020
View articletitled, Abstract 1049: Personalized neoantigen/cancer testis antigen nanovaccine (PVAC) in combination with PD-1 monoclonal antibody and/or antiangiogenic treatment in patients with metastatic solid tumors
Journal Articles

Abstract CT237: A phase I study to assess the safety, tolerability, and immunogenicity of personalized neoantigen/cancer testis antigen nanovaccine (PVAC) for high-risk resected gastric cancer

Free
Qin Liu, Hanqing Qian, Jie Shao, Qiuping Xu, Huizi Sha, Yang Yang, Weifeng Wang, Lixia Yu, Baorui Liu, Jia Wei
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): CT237.
https://doi.org/10.1158/1538-7445.AM2020-CT237
Published: 15 August 2020
View articletitled, Abstract CT237: A phase I study to assess the safety, tolerability, and immunogenicity of personalized neoantigen/cancer testis antigen nanovaccine (PVAC) for high-risk resected gastric cancer
Journal Articles

MAFB Promotes Cancer Stemness and Tumorigenesis in Osteosarcoma through a Sox9-Mediated Positive Feedback Loop

Available to Purchase
Yanyan Chen, Tao Wang, Mengxi Huang, Qin Liu, Chao Hu, Bin Wang, Dong Han, Cheng Chen, Junliang Zhang, Zhiping Li, Chao Liu, Wenbin Lei, Yue Chang, Meijuan Wu, Dan Xiang, Yitian Chen, Rui Wang, Weiqian Huang, Zengjie Lei, Xiaoyuan Chu
Journal: Cancer Research
Cancer Res (2020) 80 (12): 2472–2483.
https://doi.org/10.1158/0008-5472.CAN-19-1764
Published: 15 June 2020
View articletitled, MAFB Promotes Cancer Stemness and Tumorigenesis in Osteosarcoma through a Sox9-Mediated Positive Feedback Loop
Open the PDF for MAFB Promotes Cancer Stemness and Tumorigenesis in Osteosarcoma through a Sox9-Mediated Positive Feedback Loop in another window
Includes: Supplementary data
Journal Articles

HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer

Available to Purchase
Takeshi Fukumoto, Nail Fatkhutdinov, Joseph A. Zundell, Evgenii N. Tcyganov, Timothy Nacarelli, Sergey Karakashev, Shuai Wu, Qin Liu, Dmitry I. Gabrilovich, Rugang Zhang
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5482–5489.
https://doi.org/10.1158/0008-5472.CAN-19-1302
Published: 01 November 2019
View articletitled, HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer
Open the PDF for HDAC6 Inhibition Synergizes with Anti-PD-L1 Therapy in ARID1A-Inactivated Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail

Available to Purchase
Zhong-yi Qin, Tao Wang, Siyuan Su, Li-ting Shen, Guang-xi Zhu, Qin Liu, Liang Zhang, Ke-wei Liu, Yue Zhang, Zhi-hua Zhou, Xiao-ning Zhang, Liang-zhi Wen, Yue-liang Yao, Wen-jing Sun, Yan Guo, Kai-jun Liu, Lei Liu, Xing-wei Wang, Yan-ling Wei, Jun Wang, Hua-liang Xiao, Pengda Liu, Xiu-wu Bian, Dong-feng Chen, Bin Wang
Journal: Cancer Research
Cancer Res (2019) 79 (19): 4869–4881.
https://doi.org/10.1158/0008-5472.CAN-19-0442
Published: 01 October 2019
View articletitled, BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail
Open the PDF for BRD4 Promotes Gastric Cancer Progression and Metastasis through Acetylation-Dependent Stabilization of Snail in another window
Includes: Supplementary data
Journal Articles

Abstract 74: Heterogeneity response to afatinib in gastric cancer patient with uncommon EGFR mutations

Free
Qin Liu, Jia Wei, Yang Yang, Yue Wang, Baorui Liu, Yang Shao
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 74.
https://doi.org/10.1158/1538-7445.AM2019-74
Published: 01 July 2019
View articletitled, Abstract 74: Heterogeneity response to afatinib in gastric cancer patient with uncommon EGFR mutations