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Qian Huang
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Journal Articles

Abstract 4450: MYC upregulates MCT4 expression and promotes metabolic reprogramming and enhanced lactate utilization in LKB1-deficient NSCLC

Yu Qian, David Molkentine, Yifan Kong, Qian Huang, Chendong Yang, Alissa Poteete, Alvaro P. Guimaraes, Peixin Jiang, Ferdinandos Skoulidis, Alexandre Reuben, John D. Minna, Ralph J. DeBerardinis, John V. Heymach
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4450.
https://doi.org/10.1158/1538-7445.AM2024-4450
Published: 22 March 2024
View article titled, Abstract 4450: MYC upregulates MCT4 expression and promotes metabolic reprogramming and enhanced lactate utilization in LKB1-deficient NSCLC
Journal Articles

Abstract 5857: Trastuzumab deruxtecan resistance can be mediated by payload resistance or secondary extracellular ERBB2 mutations but sensitivity to HER2 tyrosine kinase inhibitors is maintained

Monique B. Nilsson, Xiuning Le, Junqin He, Xiaoxing Yu, Xiaofang Huo, Ashwani Kumar, Alissa Poteete, Qian Huang, Ralf Kittler, John Heymach
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5857.
https://doi.org/10.1158/1538-7445.AM2024-5857
Published: 22 March 2024
View article titled, Abstract 5857: Trastuzumab deruxtecan resistance can be mediated by payload resistance or secondary extracellular ERBB2 mutations but sensitivity to HER2 tyrosine kinase inhibitors is maintained
Journal Articles

Abstract 1935: The FAK/SRC axis mediates resistance to KRAS G12C inhibitors and its blockade can overcome KRAS inhibitor resistance

Yuji Shibata, Hibiki Udagawa, Monique B. Nilsson, Jacqulyne Robichaux, Ana Galan-Cobo, Marcelo Negrao, David P. Molkentine, Junqin He, Alissa Poteete, Yu Qian, Qian Huang, Ferdinandos Skoulidis, John V. Heymach
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1935.
https://doi.org/10.1158/1538-7445.AM2024-1935
Published: 22 March 2024
View article titled, Abstract 1935: The FAK/SRC axis mediates resistance to KRAS G12C inhibitors and its blockade can overcome KRAS inhibitor resistance
Journal Articles

Abstract 4005: HER2 TKIs enhance the anti-tumor activity of HER2-targeting CAR-T and CAR-NK cells against NSCLC

Yan Yang, Monique B. Nilsson, Alissa Poteete, Junqin He, Qian Huang, John V. Heymach
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4005.
https://doi.org/10.1158/1538-7445.AM2024-4005
Published: 22 March 2024
View article titled, Abstract 4005: HER2 TKIs enhance the anti-tumor activity of HER2-targeting CAR-T and CAR-NK cells against NSCLC
Journal Articles

Abstract 891: CD70-targeting CAR-T and CAR-NK cells demonstrate potent activity against NSCLC drug-tolerant persister cells

Yan Yang, Monique Nilsson, Sonia Patel, Xiaoxing Yu, Alissa Poteete, Qian Huang, Simon Heeke, John Heymach
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 891.
https://doi.org/10.1158/1538-7445.AM2023-891
Published: 04 April 2023
View article titled, Abstract 891: CD70-targeting CAR-T and CAR-NK cells demonstrate potent activity against NSCLC drug-tolerant persister cells
Journal Articles

Abstract NG12: From cholesterol regulation to tumor suppression: Pcsk9 as a novel target for cancer immunotherapy

Xuhui Bao, Xinjian Liu, Mengjie Hu, Hanman Chang, Meng Jiao, Jin Cheng, Liyi Xie, Qian Huang, Fang Li, Chuan-Yuan Li
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): NG12.
https://doi.org/10.1158/1538-7445.AM2021-NG12
Published: 01 July 2021
View article titled, Abstract NG12: From cholesterol regulation to tumor suppression: Pcsk9 as a novel target for cancer immunotherapy
Journal Articles

Abstract 4144: Role of CTGF in hyperthermia resistance in ovarian and uterine cancers

Hiroto Hatakeyama, Sherry Y. Wu, Yasmin A. Lyons, Sunila Pradeep, Wanqin Wang, Qian Huang, Karem A. Court, Tao Liu, Song Nie, Cristian Rodriguez-Aguayo, Fangrong Shen, Yan Huang, Takeshi Hisamatsu, Takashi Mitamura, Piotr L. Dorniak, Lingegowda S. Mangala, Marco Petrillo, Madeline Torres-Lugo, Karin D. Rodland, Anna Fagotti, Gabriel Lopez-Berestein, Chun Li, Anil K. Sood
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4144.
https://doi.org/10.1158/1538-7445.AM2017-4144
Published: 01 July 2017
View article titled, Abstract 4144: Role of CTGF in hyperthermia resistance in ovarian and uterine cancers
Journal Articles

Abstract 1318: Pancreatic cancer therapy using polyion micelles co-loaded with cyclopamine and paclitaxel

Jun Zhao, Chunhui Wu, Xiaoxia Wen, Junjie Li, Qian Huang, Ying Ma, Stephen Ullrich, Huamin Wang, Jason Fleming, Chun Li
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1318.
https://doi.org/10.1158/1538-7445.AM2016-1318
Published: 15 July 2016
View article titled, Abstract 1318: Pancreatic cancer therapy using polyion micelles co-loaded with cyclopamine and paclitaxel
Journal Articles

Abstract 4207: microPET/CT imaging of the mobilization of CD11b+ cells

Qizhen Cao, Qian Huang, Chun Li
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4207.
https://doi.org/10.1158/1538-7445.AM2016-4207
Published: 15 July 2016
View article titled, Abstract 4207: microPET/CT imaging of the mobilization of CD11b+ cells
Journal Articles

Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/β-Catenin Signaling

Ming Quan, Jiujie Cui, Tian Xia, Zhiliang Jia, Dacheng Xie, Daoyan Wei, Suyun Huang, Qian Huang, Shaojiang Zheng, Keping Xie
Journal: Cancer Research
Cancer Res (2015) 75 (22): 4778–4789.
https://doi.org/10.1158/0008-5472.CAN-14-1952
Published: 15 November 2015
View article titled, Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/β-Catenin Signaling
Open the PDF for Merlin/NF2 Suppresses Pancreatic Tumor Growth and Metastasis by Attenuating the FOXM1-Mediated Wnt/β-Catenin Signaling in another window
Includes: Supplementary data
Journal Articles

Effects of Photoacoustic Imaging and Photothermal Ablation Therapy Mediated by Targeted Hollow Gold Nanospheres in an Orthotopic Mouse Xenograft Model of Glioma

Wei Lu, Marites P. Melancon, Chiyi Xiong, Qian Huang, Andrew Elliott, Shaoli Song, Rui Zhang, Leo G. Flores, II, Juri G. Gelovani, Lihong V. Wang, Geng Ku, R. Jason Stafford, Chun Li
Journal: Cancer Research
Cancer Res (2011) 71 (19): 6116–6121.
https://doi.org/10.1158/0008-5472.CAN-10-4557
Published: 29 September 2011
View article titled, Effects of Photoacoustic Imaging and Photothermal Ablation Therapy Mediated by Targeted Hollow Gold Nanospheres in an Orthotopic Mouse Xenograft Model of Glioma
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Includes: Supplementary data
Journal Articles

Quantitative, Noninvasive Imaging of Radiation-Induced DNA Double-Strand Breaks In Vivo

Wenrong Li, Fang Li, Qian Huang, Jingping Shen, Frank Wolf, Yujun He, Xinjian Liu, Y. Angela Hu, Joel S. Bedford, Chuan-Yuan Li
Journal: Cancer Research
Cancer Res (2011) 71 (12): 4130–4137.
https://doi.org/10.1158/0008-5472.CAN-10-2540
Published: 14 June 2011
View article titled, Quantitative, Noninvasive Imaging of Radiation-Induced DNA Double-Strand Breaks <em>In Vivo</em>
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Includes: Supplementary data
Journal Articles

Tumor Site–Specific Silencing of NF-κB p65 by Targeted Hollow Gold Nanosphere–Mediated Photothermal Transfection

Wei Lu, Guodong Zhang, Rui Zhang, Leo G. Flores, II, Qian Huang, Juri G. Gelovani, Chun Li
Journal: Cancer Research
Cancer Res (2010) 70 (8): 3177–3188.
https://doi.org/10.1158/0008-5472.CAN-09-3379
Published: 14 April 2010
View article titled, Tumor Site–Specific Silencing of <em>NF-κB p65</em> by Targeted Hollow Gold Nanosphere–Mediated Photothermal Transfection
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Includes: Multimedia, Supplementary data
Journal Articles

Noninvasive Imaging and Quantification of Epidermal Growth Factor Receptor Kinase Activation In vivo

Wenrong Li, Fang Li, Qian Huang, Barbara Frederick, Shideng Bao, Chuan-Yuan Li
Journal: Cancer Research
Cancer Res (2008) 68 (13): 4990–4997.
https://doi.org/10.1158/0008-5472.CAN-07-5984
Published: 01 July 2008
View article titled, Noninvasive Imaging and Quantification of Epidermal Growth Factor Receptor Kinase Activation <em>In vivo</em>
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Includes: Supplementary data
Journal Articles

Enhancement of Hypoxia-Induced Tumor Cell Death In vitro and Radiation Therapy In vivo by Use of Small Interfering RNA Targeted to Hypoxia-Inducible Factor-1α

Xiuwu Zhang, Takashi Kon, He Wang, Fang Li, Qian Huang, Zahid N. Rabbani, John P. Kirkpatrick, Zeljko Vujaskovic, Mark W. Dewhirst, Chuan-Yuan Li
Journal: Cancer Research
Cancer Res (2004) 64 (22): 8139–8142.
https://doi.org/10.1158/0008-5472.CAN-03-2301
Published: 17 November 2004
View article titled, Enhancement of Hypoxia-Induced Tumor Cell Death <em>In vitro</em> and Radiation Therapy <em>In vivo</em> by Use of Small Interfering RNA Targeted to Hypoxia-Inducible Factor-1α
Open the PDF for Enhancement of Hypoxia-Induced Tumor Cell Death <em>In vitro</em> and Radiation Therapy <em>In vivo</em> by Use of Small Interfering RNA Targeted to Hypoxia-Inducible Factor-1α in another window
Journal Articles

GW112, A Novel Antiapoptotic Protein That Promotes Tumor Growth

Xiuwu Zhang, Qian Huang, Zhonghui Yang, Yongping Li, Chuan-Yuan Li
Journal: Cancer Research
Cancer Res (2004) 64 (7): 2474–2481.
https://doi.org/10.1158/0008-5472.CAN-03-3443
Published: 01 April 2004
View article titled, GW112, A Novel Antiapoptotic Protein That Promotes Tumor Growth
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Journal Articles

Persistent Genetic Instability in Cancer Cells Induced by Non-DNA-damaging Stress Exposures

Chuan-Yuan Li, John B. Little, Kang Hu, Wen Zhang, Li Zhang, Mark W. Dewhirst, Qian Huang
Journal: Cancer Research
Cancer Res (2001) 61 (2): 428–432.
Published: 01 January 2001
View article titled, Persistent Genetic Instability in Cancer Cells Induced by Non-DNA-damaging Stress Exposures
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Journal Articles

Heat-induced Gene Expression as a Novel Targeted Cancer Gene Therapy Strategy

Qian Huang, Jim K. Hu, Frank Lohr, Li Zhang, Rod Braun, Jennifer Lanzen, John B. Little, Mark W. Dewhirst, Chuan-Yuan Li
Journal: Cancer Research
Cancer Res (2000) 60 (13): 3435–3439.
Published: 01 July 2000
View article titled, Heat-induced Gene Expression as a Novel Targeted Cancer Gene Therapy Strategy
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