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Journal Articles

Cooperative Blockade of PKCα and JAK2 Drives Apoptosis in Glioblastoma

Robyn A. Wong, Xujun Luo, Mimi Lu, Zhenyi An, Daphne A. Haas-Kogan, Joanna J. Phillips, Kevan M. Shokat, William A. Weiss, Qi Wen Fan
Journal: Cancer Research
Cancer Res (2020) 80 (4): 709–718.
https://doi.org/10.1158/0008-5472.CAN-18-2808
Published: 14 February 2020
View article titled, Cooperative Blockade of PKCα and JAK2 Drives Apoptosis in Glioblastoma
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Includes: Supplementary data
Journal Articles

Correction: EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma

Zhenyi An, Christiane B. Knobbe-Thomsen, Xiaohua Wan, Qi Wen Fan, Guido Reifenberger, William A. Weiss
Journal: Cancer Research
Cancer Res (2019) 79 (21): 5681.
https://doi.org/10.1158/0008-5472.CAN-19-2800
Published: 01 November 2019
View article titled, Correction: EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma
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Journal Articles

EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma

Zhenyi An, Christiane B. Knobbe-Thomsen, Xiaohua Wan, Qi Wen Fan, Guido Reifenberger, William A. Weiss
Journal: Cancer Research
Cancer Res (2018) 78 (24): 6785–6794.
https://doi.org/10.1158/0008-5472.CAN-17-3551
Published: 13 December 2018
View article titled, EGFR Cooperates with EGFRvIII to Recruit Macrophages in Glioblastoma
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Includes: Supplementary data
Journal Articles

Abstract 5683: Blockade of glioma proliferation via allosteric inhibition of JAK2.

Kunyan He, Qi Qi, Chi-Bun Chan, Ge Xiao, Xia Liu, Carol Tucker-Burden, Liya Wang, Hui Mao, Xiang Lu, Frank E. McDonald, Hongbo Luo, Qi-wen Fan, William A. Weiss, Shi-yong Sun, Daniel J. Brat, Keqiang Ye
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5683.
https://doi.org/10.1158/1538-7445.AM2013-5683
Published: 15 April 2013
View article titled, Abstract 5683: Blockade of glioma proliferation via allosteric inhibition of JAK2.
Journal Articles

Abstract 2314: Erlotinib response in lung- and glioma-derived EGFR alleles: Correlating kinase site occupancy with efficacy

Krister J. Barkovich, Theodore Nicolaides, Sujatmi Hariono, Adam Garske, Qi Wen Fan, Kevan Shokat, William A. Weiss
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2314.
https://doi.org/10.1158/1538-7445.AM2011-2314
Published: 15 April 2011
View article titled, Abstract 2314: Erlotinib response in lung- and glioma-derived EGFR alleles: Correlating kinase site occupancy with efficacy
Journal Articles

Abstract 1973: Targeting activated alleles of EGFR derived from glioma and lung cancer: Correlating kinase active-site occupancy with efficacy

Theodore P. Nicolaides, Krister Barkovich, Sujatmi Hariono, Adam Garske, Qi Wen Fan, Kevan Shokat, William A. Weiss
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1973.
https://doi.org/10.1158/1538-7445.AM10-1973
Published: 15 April 2010
View article titled, Abstract 1973: Targeting activated alleles of EGFR derived from glioma and lung cancer: Correlating kinase active-site occupancy with efficacy
Journal Articles

A Dual Phosphoinositide-3-Kinase α/mTOR Inhibitor Cooperates with Blockade of Epidermal Growth Factor Receptor in PTEN-Mutant Glioma

Qi-Wen Fan, Christine K. Cheng, Theodore P. Nicolaides, Christopher S. Hackett, Zachary A. Knight, Kevan M. Shokat, William A. Weiss
Journal: Cancer Research
Cancer Res (2007) 67 (17): 7960–7965.
https://doi.org/10.1158/0008-5472.CAN-07-2154
Published: 05 September 2007
View article titled, A Dual Phosphoinositide-3-Kinase α/mTOR Inhibitor Cooperates with Blockade of Epidermal Growth Factor Receptor in <em>PTEN</em>-Mutant Glioma
Open the PDF for A Dual Phosphoinositide-3-Kinase α/mTOR Inhibitor Cooperates with Blockade of Epidermal Growth Factor Receptor in <em>PTEN</em>-Mutant Glioma in another window
Includes: Supplementary data
Journal Articles

Recovery of Map kinase signaling mediates resistance to EGFR inhibitor-based therapy in malignant glioma.

Theodore Nicolaides, Qi Wen Fan, C. James, William Weiss
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4006.
Published: 01 May 2007
View article titled, Recovery of Map kinase signaling mediates resistance to EGFR inhibitor-based therapy in malignant glioma.
Journal Articles

Combinatorial Efficacy Achieved Through Two-Point Blockade within a Signaling Pathway—A Chemical Genetic Approach

Qi-Wen Fan, Kimberly Musa Specht, Chao Zhang, Dmitriy D. Goldenberg, Kevan M. Shokat, William A. Weiss
Journal: Cancer Research
Cancer Res (2003) 63 (24): 8930–8938.
Published: 24 December 2003
View article titled, Combinatorial Efficacy Achieved Through Two-Point Blockade within a Signaling Pathway—A Chemical Genetic Approach
Open the PDF for Combinatorial Efficacy Achieved Through Two-Point Blockade within a Signaling Pathway—A Chemical Genetic Approach in another window
Includes: Supplementary data