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Journal Articles

Targeting Ferroptosis-Elicited Inflammation Suppresses Hepatocellular Carcinoma Metastasis and Enhances Sorafenib Efficacy

Ming Mu, Chun-Xiang Huang, Chuang Qu, Pei-Lin Li, Xiang-Ning Wu, Wudexin Yao, Chu Shen, Rucheng Huang, Chao-Chao Wan, Zhi-Wei Jian, Limin Zheng, Rui-Qi Wu, Xiang-Ming Lao, Dong-Ming Kuang
Journal: Cancer Research
Cancer Res (2024) 84 (6): 841–854.
https://doi.org/10.1158/0008-5472.CAN-23-1796
Published: 15 March 2024
View article titled, Targeting Ferroptosis-Elicited Inflammation Suppresses Hepatocellular Carcinoma Metastasis and Enhances Sorafenib Efficacy
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Includes: Supplementary data
Journal Articles

Abstract P2-11-18: Serum methylmalonic acid concentrations at breast cancer diagnosis are not associated with distant metastases

Qi Wu, Sigrid Hatse, Juan F. García, Patricia Altea-Manzano, Jaak Billen, Mélanie Planque, Anke Vandekeere, Yentl Lambrechts, François Richard, Annouschka Laenen, Kevin Punie, Patrick Neven, Ines Nevelsteen, Giuseppe Floris, Christine Desmedt, Ana Gomes, Sarah-Maria Fendt, Hans Wildiers
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): P2-11-18.
https://doi.org/10.1158/1538-7445.SABCS22-P2-11-18
Published: 01 March 2023
View article titled, Abstract P2-11-18: Serum methylmalonic acid concentrations at breast cancer diagnosis are not associated with distant metastases
Journal Articles

Abstract PD6-03: PD6-03 Serum methylmalonic acid concentrations at breast cancer diagnosis strongly correlate with frailty: a retrospective cross-sectional study

Qi Wu, Sigrid Hatse, Cindy Kenis, Yentl Lambrechts, Kevin Punie, Patrick Neven, Ann Smeets, Annouschka Laenen, Ana Gomes, Sarah-Maria Fendt, Hans Wildiers
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): PD6-03.
https://doi.org/10.1158/1538-7445.SABCS22-PD6-03
Published: 01 March 2023
View article titled, Abstract PD6-03: PD6-03 Serum methylmalonic acid concentrations at breast cancer diagnosis strongly correlate with frailty: a retrospective cross-sectional study
Journal Articles

Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib

Yuting Sun, Brooke A. Meyers, Barbara Czako, Paul Leonard, Faika Mseeh, Angela L. Harris, Qi Wu, Sarah Johnson, Connor A. Parker, Jason B. Cross, Maria Emilia Di Francesco, Benjamin J. Bivona, Christopher A. Bristow, Jason P. Burke, Caroline C. Carrillo, Christopher L. Carroll, Qing Chang, Ningping Feng, Guang Gao, Sonal Gera, Virginia Giuliani, Justin K. Huang, Yongying Jiang, Zhijun Kang, Jeffrey J. Kovacs, Chiu-Yi Liu, Anastasia M. Lopez, Xiaoyan Ma, Pijus K. Mandal, Timothy McAfoos, Meredith A. Miller, Robert A. Mullinax, Michael Peoples, Vandhana Ramamoorthy, Sahil Seth, Nakia D. Spencer, Erika Suzuki, Christopher C. Williams, Simon S. Yu, Andy M. Zuniga, Giulio F. Draetta, Joseph R. Marszalek, Timothy P. Heffernan, Nancy E. Kohl, Philip Jones
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (21): 4840–4853.
https://doi.org/10.1158/0008-5472.CAN-20-1634
Published: 03 November 2020
View article titled, Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib
Open the PDF for Allosteric SHP2 Inhibitor, IACS-13909, Overcomes EGFR-Dependent and EGFR-Independent Resistance Mechanisms toward Osimertinib in another window
Includes: Supplementary data
Journal Articles

Abstract 2302: Natural killer cell cancer therapy in mouse model

Shih-Wen Huang, Yein-Gei Lai, Jen-Qi Wu, Yae-Huei Liou, Nan-Shih Liao
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 2302.
https://doi.org/10.1158/1538-7445.AM2019-2302
Published: 01 July 2019
View article titled, Abstract 2302: Natural killer cell cancer therapy in mouse model
Journal Articles

Abstract 1986: Breast cancer-secreted exosomes stimulate beige/brown differentiation and reprogram metabolism in stromal adipocytes to promote tumor progression

Juanjuan Li, Qi Wu, Zhiyu Li, Si Sun, Shan Zhu, Lijun Wang, Juan Wu, Yimin Zhang, Jingping Yuan, Shengrong Sun, Changhua Wang
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 1986.
https://doi.org/10.1158/1538-7445.AM2019-1986
Published: 01 July 2019
View article titled, Abstract 1986: Breast cancer-secreted exosomes stimulate beige/brown differentiation and reprogram metabolism in stromal adipocytes to promote tumor progression
Journal Articles

Abstract 3277: IACS-9779, a development candidate that inhibits 2,3-dioxygenase (IDO) activity by blocking heme incorporation into IDO apoenzyme

Faika Mseeh, Matthew M. Hamilton, Joseph R. Marszalek, Norma E. Rogers, Connor A. Parker, Simon S. Yu, Zhen Liu, Naphtali J. Reyna, Timothy McAfoos, Brett W. Virgin-Downey, Paul G. Leonard, Jason B. Cross, Ningping Feng, Angela L. Harris, Andy M. Zuniga, Keith Mikule, Martin Tremblay, Yongying Jiang, Mikhila Mahendra, Jihai Pang, Qi Wu, Quanyun Xu, Timothy P. Heffernan, Philip Jones, Richard T. Lewis
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3277.
https://doi.org/10.1158/1538-7445.AM2019-3277
Published: 01 July 2019
View article titled, Abstract 3277: IACS-9779, a development candidate that inhibits 2,3-dioxygenase (IDO) activity by blocking heme incorporation into IDO apoenzyme
Journal Articles

Abstract LB-071: Discovery of an imidazopyridine series of potent human IDO1 inhibitors with robust target engagement in a preclinical tumor model

Alessia Petrocchi, Naphtali J. Reyna, Faika Mseeh, Connor A. Parker, Simon Yu, Quanyun Xu, Ningping Feng, Paul Leonard, Norma Rogers, Jason B. Cross, Angela L. Harris, Yongying Jiang, Tin Oo Khor, Mikhila G. Mahendra, Jihai Pang, Qi Wu, Andy M. Zuniga, Timothy McAfoos, Timothy McAfoos, Matthew M. Hamilton, Joe R. Marszalek, Keith Mikule, Paul Vancutsem, Keith Wilcoxen, Martin Tremblay, Philip Jones, Richard T. Lewis
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): LB-071.
https://doi.org/10.1158/1538-7445.AM2018-LB-071
Published: 01 July 2018
View article titled, Abstract LB-071: Discovery of an imidazopyridine series of potent human IDO1 inhibitors with robust target engagement in a preclinical tumor model
Journal Articles

Abstract 702: IMLEC: A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1

Fei Tang, Peng Zhang, Peiying Ye, Christopher A. Lazarski, Qi Wu, Ingrid L. Bergin, Timothy P. Bender, Michael N. Hall, Ya Cui, Liguo Zhang, Taijiao Jiang, Yang Liu, Pan Zheng
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 702.
https://doi.org/10.1158/1538-7445.AM2018-702
Published: 01 July 2018
View article titled, Abstract 702: IMLEC: A population of innate myelolymphoblastoid effector cell expanded by inactivation of mTOR complex 1
Journal Articles

Abstract LB-69: Novel WBC gene expression assay for prostate cancer detection.

Amin I. Kassis, Qi Wu, Maliackal Poulo Joy, Pichumani Balagurumoorthy, Massimo Loda, Carolyn Evan, Gillian Petrozziello, Philip W. Kantoff, S. James Adelstein
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): LB-69.
https://doi.org/10.1158/1538-7445.AM2013-LB-69
Published: 15 April 2013
View article titled, Abstract LB-69: Novel WBC gene expression assay for prostate cancer detection.
Journal Articles

The mismatch repair proteins, MSH2 and MLH1, contribute differently to cellular responses to DNA interstrand crosslinks in human cells

Qi Wu, Stephanie Gilley, Karen Vasquez
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 858.
Published: 01 May 2008
View article titled, The mismatch repair proteins, MSH2 and MLH1, contribute differently to cellular responses to DNA interstrand crosslinks in human cells
Journal Articles

The role of mismatch repair in processing DNA interstrand crosslinks in human cells

Qi Wu, Karen Vasquez
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 895.
Published: 01 May 2007
View article titled, The role of mismatch repair in processing DNA interstrand crosslinks in human cells
Journal Articles

Therapeutic Effect of Rapamycin on Gallbladder Cancer in a Transgenic Mouse Model

Qi Wu, Kaoru Kiguchi, Toru Kawamoto, Tetsuo Ajiki, Jeanine Traag, Steve Carbajal, Lynnsie Ruffino, Howard Thames, Ignacio Wistuba, Melanie Thomas, Karen M. Vasquez, John DiGiovanni
Journal: Cancer Research
Cancer Res (2007) 67 (8): 3794–3800.
https://doi.org/10.1158/0008-5472.CAN-06-3214
Published: 17 April 2007
View article titled, Therapeutic Effect of Rapamycin on Gallbladder Cancer in a Transgenic Mouse Model
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Journal Articles

Regulation of Stat3 gene transcription by triplex-forming oliogonucleotides in mice

Qi Wu, Steve Carbajal, Jeanine Traag, Penny K. Riggs, Earl F. Walborg, John Digiovanni, Karen M. Vasquez
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 709.
Published: 15 April 2006
View article titled, Regulation of Stat3 gene transcription by triplex-forming oliogonucleotides in mice
Journal Articles

Enhancement of 5-Fluorouracil Sensitivity by an rTS Signaling Mimic in H630 Colon Cancer Cells

Ree Dolnick, Qi Wu, Norman J. Angelino, Lawrence V. Stephanie, Kuan-Chih Chow, Janice R. Sufrin, Bruce J. Dolnick
Journal: Cancer Research
Cancer Res (2005) 65 (13): 5917–5924.
https://doi.org/10.1158/0008-5472.CAN-05-0431
Published: 01 July 2005
View article titled, Enhancement of 5-Fluorouracil Sensitivity by an <em>rTS</em> Signaling Mimic in H630 Colon Cancer Cells
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Journal Articles

Mismatch repair participates in an error-free processing of DNA interstrand crosslinks in human cells

Qi Wu, Laura A. Christensen, Randy J. Legerski, Karen M. Vasquez
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 833.
Published: 01 May 2005
View article titled, Mismatch repair participates in an error-free processing of DNA interstrand crosslinks in human cells
Journal Articles

Sigma-2 receptor gene expression involves in tumor cell cycles and cell proliferation

Li-Ming Wang, Qi Wu, Robert H. Mach, K. T. Wheeler, Kathryn A. Morton
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1288–1289.
Published: 01 May 2005
View article titled, Sigma-2 receptor gene expression involves in tumor cell cycles and cell proliferation
Journal Articles

Rapamycin inhibits the development of gallbladder adenocarcinoma in BK5.erbB2 transgenic mice

Qi Wu, Kaoru Kiguchi, Ajiki Tetsuo, Toru Kawamoto, Donna Dudek, Lynnsie Ruffino, Jeanine Traag, Karen M. Vasquez, John Digiovanni
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1182.
Published: 01 April 2004
View article titled, Rapamycin inhibits the development of gallbladder adenocarcinoma in BK5.erbB2 transgenic mice
Journal Articles

Mismatch repair participates in an error-free repair of psoralen crosslinks in human cells.

Qi Wu, Laura A. Christensen, Kelsey E. Gray, Karen M. Vasquez
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 525–526.
Published: 01 April 2004
View article titled, Mismatch repair participates in an error-free repair of psoralen crosslinks in human cells.
Journal Articles

Loss of 3p13→p21.2 in Tumorigenic Reversion of a Hybrid between Isogeneic Nontumorigenic and Tumorigenic Human Uroepithelial Cells

Aloysius J. Klingelhutz, Shi-Qi Wu, Jinwen Huang, Catherine A. Reznikoff
Journal: Cancer Research
Cancer Res (1992) 52 (6): 1631–1634.
Published: 01 March 1992
View article titled, Loss of 3p13→p21.2 in Tumorigenic Reversion of a Hybrid between Isogeneic Nontumorigenic and Tumorigenic Human Uroepithelial Cells
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