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Journal Articles

Abstract LB426: Targeting oncogenic FLT3-ITD by USP10 inhibitors for the treatment of FLT3-ITD AML

Free
Amirreza Samarbakhsh, Jianlei Zhao, Sadaf Dorandish, Jenna Thibodeau, Elyas Khan, Q. Ping Dou, Lisa Polin, Juiwanna Kushner, Jeffrey W. Taub, Yubin Ge, Navnath S. Gavande
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_2): LB426.
https://doi.org/10.1158/1538-7445.AM2025-LB426
Published: 25 April 2025
View articletitled, Abstract LB426: Targeting oncogenic FLT3-ITD by USP10 inhibitors for the treatment of FLT3-ITD AML
Journal Articles

Abstract 162: A prodrug of green tea polyphenol (-)-epigallocatechin-3-gallate served as a potentially novel angiogenesis inhibitor in endometrioid endometrial cancer

Free
Jianzhang Wang, Chi Wai Man, Xueying Yang, Joseph Kwong, Q. Ping Dou, Tak Hang Chan, Chi Chiu Wang
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 162.
https://doi.org/10.1158/1538-7445.AM2017-162
Published: 01 July 2017
View articletitled, Abstract 162: A prodrug of green tea polyphenol (-)-epigallocatechin-3-gallate served as a potentially novel angiogenesis inhibitor in endometrioid endometrial cancer
Journal Articles

Abstract 5564: Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis.

Free
Ying Wang, Vino T. Cheryan, Shazia Jamal, Di Chen, Huanjie Yang, Lisa A. Polin, Harvey I. Pass, Q Ping Dou, Sunita Sharma, Arun K. Rishi, Anil Wali
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5564.
https://doi.org/10.1158/1538-7445.AM2013-5564
Published: 15 April 2013
View articletitled, Abstract 5564: Disulfiram suppresses growth of the malignant pleural mesothelioma cells in part by inducing apoptosis.
Journal Articles

Abstract 3982: Immuno-sensitization of malignant gliomas by natural polyphenols.

Free
Chandramouli Mandalaparty, Andrew Huang, Sandeep Mittal, Agnes M. Rimando, Q. Ping Dou, Prahlad Parajuli
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3982.
https://doi.org/10.1158/1538-7445.AM2013-3982
Published: 15 April 2013
View articletitled, Abstract 3982: Immuno-sensitization of malignant gliomas by natural polyphenols.
Journal Articles

Abstract 2779: Withaferin A inhibits the malignant pleural mesothelioma growth in vitro and in vivo

Free
Huanjie Yang, Ying Wang, Vino T. Cheriyan, Wenjuan Wu, Cindy Qiuzhi Cui, Lisa A. Polin, Harvey I. Pass, Q. Ping Dou, Arun K. Rishi, Anil Wali
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2779.
https://doi.org/10.1158/1538-7445.AM2012-2779
Published: 15 April 2012
View articletitled, Abstract 2779: Withaferin A inhibits the malignant pleural mesothelioma growth in vitro and in vivo
Journal Articles

Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells In vitro and In vivo

Free
Haijun Zhang, Di Chen, Jonathan Ringler, Wei Chen, Qiuzhi Cindy Cui, Stephen P. Ethier, Q. Ping Dou, Guojun Wu
Journal: Cancer Research
Cancer Res (2010) 70 (10): 3996–4004.
https://doi.org/10.1158/0008-5472.CAN-09-3752
Published: 12 May 2010
View articletitled, Disulfiram Treatment Facilitates Phosphoinositide 3-Kinase Inhibition in Human Breast Cancer Cells In vitro and In vivo
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Includes: Supplementary data
Journal Articles

Abstract 4446: Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines

Free
Ying Wang, Arun K. Rishi, Vineshkumar T. Puliappadamba, Sunita Sharma, Huanjie Yang, Adi Tarca, Q. Ping Dou, Fulvio Lonardo, John C. Ruckdeschel, Harvey I. Pass, Anil Wali
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 4446.
https://doi.org/10.1158/1538-7445.AM10-4446
Published: 15 April 2010
View articletitled, Abstract 4446: Targeted proteasome inhibition by Velcade induces apoptosis in human mesothelioma and breast cancer cell lines
Journal Articles

Curcumin Inhibits the Proteasome Activity in Human Colon Cancer Cells In vitro and In vivo

Free
Vesna Milacic, Sanjeev Banerjee, Kristin R. Landis-Piwowar, Fazlul H. Sarkar, Adhip P.N. Majumdar, Q. Ping Dou
Journal: Cancer Research
Cancer Res (2008) 68 (18): 7283–7292.
https://doi.org/10.1158/0008-5472.CAN-07-6246
Published: 14 September 2008
View articletitled, Curcumin Inhibits the Proteasome Activity in Human Colon Cancer Cells In vitro and In vivo
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Journal Articles

Inhibition of the Proteasome Activity by Gallium(III) Complexes Contributes to Their Anti–Prostate Tumor Effects

Free
Di Chen, Michael Frezza, Rajendra Shakya, Qiuzhi Cindy Cui, Vesna Milacic, Claudio N. Verani, Q. Ping Dou
Journal: Cancer Research
Cancer Res (2007) 67 (19): 9258–9265.
https://doi.org/10.1158/0008-5472.CAN-07-1813
Published: 01 October 2007
View articletitled, Inhibition of the Proteasome Activity by Gallium(III) Complexes Contributes to Their Anti–Prostate Tumor Effects
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Journal Articles

Androgen Receptor– and E2F-1–Targeted Thymoquinone Therapy for Hormone-Refractory Prostate Cancer

Free
Ahmed O. Kaseb, Kannagi Chinnakannu, Di Chen, Arun Sivanandam, Sheela Tejwani, Mani Menon, Q. Ping Dou, G. Prem-Veer Reddy
Journal: Cancer Research
Cancer Res (2007) 67 (16): 7782–7788.
https://doi.org/10.1158/0008-5472.CAN-07-1483
Published: 15 August 2007
View articletitled, Androgen Receptor– and E2F-1–Targeted Thymoquinone Therapy for Hormone-Refractory Prostate Cancer
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Journal Articles

A Novel Prodrug of the Green Tea Polyphenol (−)-Epigallocatechin-3-Gallate as a Potential Anticancer Agent

Free
Kristin R. Landis-Piwowar, Congde Huo, Di Chen, Vesna Milacic, Guoqing Shi, Tak Hang Chan, Q. Ping Dou
Journal: Cancer Research
Cancer Res (2007) 67 (9): 4303–4310.
https://doi.org/10.1158/0008-5472.CAN-06-4699
Published: 04 May 2007
View articletitled, A Novel Prodrug of the Green Tea Polyphenol (−)-Epigallocatechin-3-Gallate as a Potential Anticancer Agent
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Journal Articles

Clioquinol, a therapeutic agent for Alzheimer’s disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, anti-angiogenic and anti-tumor activities in human prostate cancer cells and xenografts

Free
Di Chen, Cindy Cui, Huanjie Yang, Raul Barrea, Fazlul Sarkar, Shijie Sheng, Bing Yan, G Prem Reddy, Q. Ping Dou
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4841.
Published: 01 May 2007
View articletitled, Clioquinol, a therapeutic agent for Alzheimer’s disease, has proteasome-inhibitory, androgen receptor-suppressing, apoptosis-inducing, anti-angiogenic and anti-tumor activities in human prostate cancer cells and xenografts
Journal Articles

Role of Ubiquitin-proteasome proteolytic pathway in malignant pleural mesothelioma.

Free
Anil Wali, Ying Wang, Deepa Kanakapalli, Zhandong Liu, Sunita Sharma, Fulvio Lonardo, Arun Rishi, Adhip Majumdar, Q. Ping Dou, Michele Carbone, John Ruckdeschel, Harvey Pass
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4406.
Published: 01 May 2007
View articletitled, Role of Ubiquitin-proteasome proteolytic pathway in malignant pleural mesothelioma.
Journal Articles

Clioquinol, a Therapeutic Agent for Alzheimer's Disease, Has Proteasome-Inhibitory, Androgen Receptor–Suppressing, Apoptosis-Inducing, and Antitumor Activities in Human Prostate Cancer Cells and Xenografts

Free
Di Chen, Qiuzhi Cindy Cui, Huanjie Yang, Raul A. Barrea, Fazlul H. Sarkar, Shijie Sheng, Bing Yan, G. Prem Veer Reddy, Q. Ping Dou
Journal: Cancer Research
Cancer Res (2007) 67 (4): 1636–1644.
https://doi.org/10.1158/0008-5472.CAN-06-3546
Published: 16 February 2007
View articletitled, Clioquinol, a Therapeutic Agent for Alzheimer's Disease, Has Proteasome-Inhibitory, Androgen Receptor–Suppressing, Apoptosis-Inducing, and Antitumor Activities in Human Prostate Cancer Cells and Xenografts
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Journal Articles

Calmodulin-Androgen Receptor (AR) Interaction: Calcium-Dependent, Calpain-Mediated Breakdown of AR in LNCaP Prostate Cancer Cells

Free
Ronald P. Pelley, Kannagi Chinnakannu, Shalini Murthy, Faith M. Strickland, Mani Menon, Q. Ping Dou, Evelyn R. Barrack, G. Prem-Veer Reddy
Journal: Cancer Research
Cancer Res (2006) 66 (24): 11754–11762.
https://doi.org/10.1158/0008-5472.CAN-06-2918
Published: 18 December 2006
View articletitled, Calmodulin-Androgen Receptor (AR) Interaction: Calcium-Dependent, Calpain-Mediated Breakdown of AR in LNCaP Prostate Cancer Cells
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Journal Articles

A Novel Anticancer Gold(III) Dithiocarbamate Compound Inhibits the Activity of a Purified 20S Proteasome and 26S Proteasome in Human Breast Cancer Cell Cultures and Xenografts

Free
Vesna Milacic, Di Chen, Luca Ronconi, Kristin R. Landis-Piwowar, Dolores Fregona, Q. Ping Dou
Journal: Cancer Research
Cancer Res (2006) 66 (21): 10478–10486.
https://doi.org/10.1158/0008-5472.CAN-06-3017
Published: 01 November 2006
View articletitled, A Novel Anticancer Gold(III) Dithiocarbamate Compound Inhibits the Activity of a Purified 20S Proteasome and 26S Proteasome in Human Breast Cancer Cell Cultures and Xenografts
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Journal Articles

Disulfiram, a Clinically Used Anti-Alcoholism Drug and Copper-Binding Agent, Induces Apoptotic Cell Death in Breast Cancer Cultures and Xenografts via Inhibition of the Proteasome Activity

Free
Di Chen, Qiuzhi Cindy Cui, Huanjie Yang, Q. Ping Dou
Journal: Cancer Research
Cancer Res (2006) 66 (21): 10425–10433.
https://doi.org/10.1158/0008-5472.CAN-06-2126
Published: 01 November 2006
View articletitled, Disulfiram, a Clinically Used Anti-Alcoholism Drug and Copper-Binding Agent, Induces Apoptotic Cell Death in Breast Cancer Cultures and Xenografts via Inhibition of the Proteasome Activity
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Journal Articles

Celastrol, a Triterpene Extracted from the Chinese “Thunder of God Vine,” Is a Potent Proteasome Inhibitor and Suppresses Human Prostate Cancer Growth in Nude Mice

Free
Huanjie Yang, Di Chen, Qiuzhi Cindy Cui, Xiao Yuan, Q. Ping Dou
Journal: Cancer Research
Cancer Res (2006) 66 (9): 4758–4765.
https://doi.org/10.1158/0008-5472.CAN-05-4529
Published: 01 May 2006
View articletitled, Celastrol, a Triterpene Extracted from the Chinese “Thunder of God Vine,” Is a Potent Proteasome Inhibitor and Suppresses Human Prostate Cancer Growth in Nude Mice
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Journal Articles

Computational modeling and biological evaluation of methylated (-)-EGCG analogs

Free
Kristin R. Landis-Piwowar, Sheng Biao Wan, Kenyon G. Daniel, Di Chen, Tak Hang Chan, Q. Ping Dou
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1151.
Published: 15 April 2006
View articletitled, Computational modeling and biological evaluation of methylated (-)-EGCG analogs
Journal Articles

CEP1612, a Dipeptidyl Proteasome Inhibitor, Induces p21WAF1 and p27KIP1 Expression and Apoptosis and Inhibits the Growth of the Human Lung Adenocarcinoma A-549 in Nude Mice

Free
Jiazhi Sun, Sangkil Nam, Chang-Sun Lee, Benyi Li, Domenico Coppola, Andrew D. Hamilton, Q. Ping Dou, Saïd M. Sebti
Journal: Cancer Research
Cancer Res (2001) 61 (4): 1280–1284.
Published: 02 February 2001
View articletitled, CEP1612, a Dipeptidyl Proteasome Inhibitor, Induces p21WAF1 and p27KIP1 Expression and Apoptosis and Inhibits the Growth of the Human Lung Adenocarcinoma A-549 in Nude Mice
Open the PDF for CEP1612, a Dipeptidyl Proteasome Inhibitor, Induces p21WAF1 and p27KIP1 Expression and Apoptosis and Inhibits the Growth of the Human Lung Adenocarcinoma A-549 in Nude Mice in another window