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Journal Articles

Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration

Open Access
Sunyana Gadal, Jacob A. Boyer, Simon F. Roy, Noah A. Outmezguine, Malvika Sharma, Hongyan Li, Ning Fan, Eric Chan, Yevgeniy Romin, Afsar Barlas, Qing Chang, Priya Pancholi, Neilawattie Merna Timaul, Michael Overholtzer, Rona Yaeger, Katia Manova-Todorova, Elisa de Stanchina, Marcus W. Bosenberg, Neal Rosen
Journal: Cancer Research
Cancer Res (2025) 85 (9): 1611–1627.
https://doi.org/10.1158/0008-5472.CAN-24-2220
Published: 02 May 2025
View articletitled, Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration
Open the PDF for Tumorigenesis Driven by BRAFV600E Requires Secondary Mutations That Overcome Its Feedback Inhibition of RAC1 and Migration in another window
Includes: Multimedia, Supplementary data
Journal Articles

Abstract 253: Diet induced insulin resistance is due to induction of expression of tumor suppressor pten

Free
Radha Mukherjee, Priya Pancholi, Malvika Sharma, Hilla Solomon, Merna N. Timaul, Vladimir Markov, Elisa de Stanchina de Stanchina, Kiran Vanaja, Neal Rosen
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 253.
https://doi.org/10.1158/1538-7445.AM2025-253
Published: 21 April 2025
View articletitled, Abstract 253: Diet induced insulin resistance is due to induction of expression of tumor suppressor pten
Journal Articles

Abstract 2034: Discovery of novel therapeutic targets using 3D chromatin conformation and patient-specific gene regulatory networks

Free
Andre Neil Forbes, Duo Xu, Sandra Cohen, Ann Palladino, Priya Pancholi, Ekta Khurana
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 2034.
https://doi.org/10.1158/1538-7445.AM2023-2034
Published: 04 April 2023
View articletitled, Abstract 2034: Discovery of novel therapeutic targets using 3D chromatin conformation and patient-specific gene regulatory networks
Journal Articles

Abstract 1706: A non-canonical MiT/TFE-dependent NRF2 program is a druggable vulnerability in multiple cancer types

Free
Xinbo Luo, Bart Lutterbach, Priya Pancholi, Yeon Sook Choi, Xiao Liu, Phillip Munson, Saqib Faisal, David A. Whipple, Robert A. Smith, Warren S. Weiner, David K. Johnson, Myriam Boukhali, Nicole S. Persky, Matthew G. Rees, Shunsuke Kitajima, David Barbie, Anuradha Roy, Michael Baltezor, Lian Rajewski, William McGuinness, John Haslam, Ananthan Sadagopan, Charles H. Yoon, Cory M. Johannessen, Christine G. Lian, Jason L. Hornick, Srinivas R. Viswanathan, David Liu, Vicki Nienaber, Wilhelm Haas, Frank J. Schoenen, David E. Fisher, Rizwan Haq
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1706.
https://doi.org/10.1158/1538-7445.AM2023-1706
Published: 04 April 2023
View articletitled, Abstract 1706: A non-canonical MiT/TFE-dependent NRF2 program is a druggable vulnerability in multiple cancer types
Journal Articles

Abstract 5805: Palbociclib synergistically enhances the anticancer activity of cisplatin in P53 mutant model of upper gastrointestinal cancers

Free
Dhvanir Kansara, Amruta Samant, Priya Pancholi, Tanvi Visal, Shraddha Patel, Vikas Sehdev
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5805.
https://doi.org/10.1158/1538-7445.AM2018-5805
Published: 01 July 2018
View articletitled, Abstract 5805: Palbociclib synergistically enhances the anticancer activity of cisplatin in P53 mutant model of upper gastrointestinal cancers
Journal Articles

Abstract 1698: Loss of MHC-I expression is associated with altered immune microenvironment and decreased response to PD-1 checkpoint inhibition

Free
Cecile Gstalder, Priya Pancholi, Dorota Sadowicz, Rizwan Haq
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1698.
https://doi.org/10.1158/1538-7445.AM2018-1698
Published: 01 July 2018
View articletitled, Abstract 1698: Loss of MHC-I expression is associated with altered immune microenvironment and decreased response to PD-1 checkpoint inhibition
Journal Articles

Abstract 2800: Design, synthesis, selection, and evaluation of a potent multi-kinase targeting N4-phenylsubstituted-7H-pyrrolo[2,3-d]pyrimidin-4-amine derivative with significant anticancer activity in P53 mutant and wild type models of upper gastrointestinal cancers

Free
Amruta Samant, Tanvi Visal, Priya Pancholi, Dhvanir Kansara, Tanmay Dichwalkar, Robert Senones, Sonali Kurup, Vikas Sehdev
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 2800.
https://doi.org/10.1158/1538-7445.AM2018-2800
Published: 01 July 2018
View articletitled, Abstract 2800: Design, synthesis, selection, and evaluation of a potent multi-kinase targeting N4-phenylsubstituted-7H-pyrrolo[2,3-d]pyrimidin-4-amine derivative with significant anticancer activity in P53 mutant and wild type models of upper gastrointestinal cancers
Journal Articles

Abstract 4180: RS-41, a multi-targeted kinase inhibitor, induces cell cycle arrest and apoptosis in p53 mutant and wild type models of upper gastrointestinal cancers

Free
Tanvi Visal, Shraddha Patel, Priya Pancholi, Samhita Bapat, Amruta Samant, Dhvanir Kansara, Sonali Kurup, Vikas Sehdev
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4180.
https://doi.org/10.1158/1538-7445.AM2017-4180
Published: 01 July 2017
View articletitled, Abstract 4180: RS-41, a multi-targeted kinase inhibitor, induces cell cycle arrest and apoptosis in p53 mutant and wild type models of upper gastrointestinal cancers
Journal Articles

Abstract 2172: ON 123300, an orally administered novel CDK4/6 + ARK5 inhibitor, exhibits potent antitumor activity in vivo: comparative studies with Palbociclib

Free
Shraddha Patel, Priya Pancholi, Tanvi Visal, Amruta Samant, Dhvanir Kansara, V J. Rajadhyaksha, Benjamin S. Hoffman, Manoj Maniar, Vikas Sehdev
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2172.
https://doi.org/10.1158/1538-7445.AM2017-2172
Published: 01 July 2017
View articletitled, Abstract 2172: ON 123300, an orally administered novel CDK4/6 + ARK5 inhibitor, exhibits potent antitumor activity in vivo: comparative studies with Palbociclib
Journal Articles

Abstract 4687: Rigosertib synergistically enhances the anticancer activity of Cisplatin in various preclinical models of upper gastrointestinal cancers

Free
Priya Pancholi, Tanmay Dichwalkar, Samhita Bapat, V. J. Rajadhyaksha, Benjamin S. Hoffman, Manoj Maniar, Vikas Sehdev
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4687.
https://doi.org/10.1158/1538-7445.AM2016-4687
Published: 15 July 2016
View articletitled, Abstract 4687: Rigosertib synergistically enhances the anticancer activity of Cisplatin in various preclinical models of upper gastrointestinal cancers
Journal Articles

Abstract 2200: Omega-3 fatty acid conjugated paclitaxel dendrimers exhibit enhanced anticancer activity in various preclinical models of gastrointestinal cancers

Free
Tanmay Dichwalkar, Samhita Bapat, Priya Pancholi, V. K. Yellepeddi, Vikas Sehdev
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2200.
https://doi.org/10.1158/1538-7445.AM2016-2200
Published: 15 July 2016
View articletitled, Abstract 2200: Omega-3 fatty acid conjugated paclitaxel dendrimers exhibit enhanced anticancer activity in various preclinical models of gastrointestinal cancers
Journal Articles

Abstract 4776: Dichloro [4,40-bis(4,4,4-trifluorobutyl)-2,20-bipyridine] platinum, a novel Cisplatin analog, exhibits enhanced anticancer activity in preclinical models of upper gastrointestinal cancers

Free
Samhita Bapat, Tanmay Dichwalkar, Priya Pancholi, Byron L. Bennett, Vikas Sehdev
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4776.
https://doi.org/10.1158/1538-7445.AM2016-4776
Published: 15 July 2016
View articletitled, Abstract 4776: Dichloro [4,40-bis(4,4,4-trifluorobutyl)-2,20-bipyridine] platinum, a novel Cisplatin analog, exhibits enhanced anticancer activity in preclinical models of upper gastrointestinal cancers