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Prahlad Ram
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Journal Articles

Abstract 668: Induction of mammary carcinoma in tetracycline-inducible cMET(T1010I) transgenic mice

Chuanwei Yang, Ana M. Gonzalez, Naoto T. Ueno, Shuying Liu, Jinsong Zhang, Gordon B. Mills, John Mendelsohn, Prahlad Ram
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 668.
https://doi.org/10.1158/1538-7445.AM2016-668
Published: 15 July 2016
View article titled, Abstract 668: Induction of mammary carcinoma in tetracycline-inducible cMET(T1010I) transgenic mice
Journal Articles

Abstract 1199: Systems-based approach identifies altered carbohydrate metabolism as a predictor of a malignant phenotype in ovarian cancer

Rebecca A. Previs, Tyler J. Moss, Behrouz Zand, Rajesha Rupaimoole, Heather J. Dalton, Jean M. Hansen, Guillermo Armaiz-Pena, Susan Lutgendorf, Robert L. Coleman, Pratip Bhattacharya, Prahlad Ram, Anil K. Sood
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1199.
https://doi.org/10.1158/1538-7445.AM2015-1199
Published: 01 August 2015
View article titled, Abstract 1199: Systems-based approach identifies altered carbohydrate metabolism as a predictor of a malignant phenotype in ovarian cancer
Journal Articles

Abstract 5466: Integrative TCGA analyses identify Basonuclin1 (BNC1) as a key mediator for platinum resistance

Sherry Y. Wu, Justyna Filant, Michael McGuire, Rajesha Rupaimoole, Sunila Pradeep, Anna Unruh, Herbrich Shelley, Cristina Ivan, Ruder Dennis, Cristian Rodriguez-Aguayo, Vasudha Sehgal, Takahito Miyake, Archana Nagaraja, Kshipra Gharpure, Guillermo Armaiz, Rebecca Previs, Gabriel Lopez-Berestein, Prahlad Ram, Keith Baggerly, Anil Sood
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5466.
https://doi.org/10.1158/1538-7445.AM2015-5466
Published: 01 August 2015
View article titled, Abstract 5466: Integrative TCGA analyses identify Basonuclin1 (BNC1) as a key mediator for platinum resistance
Journal Articles

Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma

Y.N. Vashisht Gopal, Helen Rizos, Guo Chen, Wanleng Deng, Dennie T. Frederick, Zachary A. Cooper, Richard A. Scolyer, Gulietta Pupo, Kakajan Komurov, Vasudha Sehgal, Jiexin Zhang, Lalit Patel, Cristiano G. Pereira, Bradley M. Broom, Gordon B. Mills, Prahlad Ram, Paul D. Smith, Jennifer A. Wargo, Georgina V. Long, Michael A. Davies
Journal: Cancer Research
Cancer Res (2014) 74 (23): 7037–7047.
https://doi.org/10.1158/0008-5472.CAN-14-1392
Published: 30 November 2014
View article titled, Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma
Open the PDF for Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma in another window
Includes: Supplementary data
Journal Articles

Abstract 1406: Evoking potent RNAi response using novel 2′-OMe-phosphorodithioated modified siRNAs

Sherry Wu, Xianbin Yang, Martin Egli, Kshipra Ghaupure, Hiroto Hatakeyama, Michael McGuire, Rajesha Rupaimoole, Takahito Miyake, Morgan Taylor, Sunila Pradeep, Archana Nagaraja, Malgorzata Sierant, Richa Singhania, Cristian Rodriguez-Aguayo, Nigel McMillan, Gabriel Lopez-Berestein, Prahlad Ram, Barbara Nawrot, Anil K. Sood
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 1406.
https://doi.org/10.1158/1538-7445.AM2014-1406
Published: 01 October 2014
View article titled, Abstract 1406: Evoking potent RNAi response using novel 2′-OMe-phosphorodithioated modified siRNAs
Journal Articles

Abstract 4396: MicroRNA MIR551B amplified at 3q26.2 locus activate c-KIT expression and causes resistance to anoikis of ovarian cancer cells

Pradeep Chaluvally-Raghavan, Fan Zhang, Wenbin Liu, Moss Tyler, Shuangxing Yu, Sunila Pradeep, Prahlad Ram, Yiling Lu, Anil Sood, Gordon Mills
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 4396.
https://doi.org/10.1158/1538-7445.AM2014-4396
Published: 01 October 2014
View article titled, Abstract 4396: MicroRNA MIR551B amplified at 3q26.2 locus activate c-KIT expression and causes resistance to anoikis of ovarian cancer cells
Journal Articles

Notch3 Pathway Alterations in Ovarian Cancer

Wei Hu, Tao Liu, Cristina Ivan, Yunjie Sun, Jie Huang, Lingegowda S. Mangala, Takahito Miyake, Heather J. Dalton, Sunila Pradeep, Rajesh Rupaimoole, Rebecca A. Previs, Hee Dong Han, Justin Bottsford-Miller, Behrouz Zand, Yu Kang, Chad V. Pecot, Alpa M. Nick, Sherry Y. Wu, Ju-Seog Lee, Vasudha Sehgal, Prahlad Ram, Jinsong Liu, Susan L. Tucker, Gabriel Lopez-Berestein, Keith A. Baggerly, Robert L. Coleman, Anil K. Sood
Journal: Cancer Research
Cancer Res (2014) 74 (12): 3282–3293.
https://doi.org/10.1158/0008-5472.CAN-13-2066
Published: 12 June 2014
View article titled, Notch3 Pathway Alterations in Ovarian Cancer
Open the PDF for Notch3 Pathway Alterations in Ovarian Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 2036: Overcoming platinum-resistance in ovarian cancer via targeting basonuclin1 (BNC1).

Sherry Y. Wu, Anna K. Unruh, Rajesha Rupaimoole, Cristina Ivan, Dennis Ruder, Sunila Pradeep, Vasudha Sehgal, Cristian Rodriguez-Aguayo, Chad Pecot, Takahito Miyake, Gabriel Lopez-Berestein, Prahlad Ram, Keith A. Baggerly, Anil K. Sood
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2036.
https://doi.org/10.1158/1538-7445.AM2013-2036
Published: 15 April 2013
View article titled, Abstract 2036: Overcoming platinum-resistance in ovarian cancer via targeting basonuclin1 (BNC1).
Journal Articles

Abstract 4920: Integrative identification of stochastically activated signaling sub-networks in individual cancer cells

Iadevaia Sergio, Prahlad Ram
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4920.
https://doi.org/10.1158/1538-7445.AM2011-4920
Published: 15 April 2011
View article titled, Abstract 4920: Integrative identification of stochastically activated signaling sub-networks in individual cancer cells
Journal Articles

Abstract 4138: Five prognostic subgroups differ in expression of Akt pathway genes: Biomarkers for therapy selection

Anna M. Joy, Ivan Smirnov, Archana Ramesh, Seungchan Kim, Robert Bachoo, Jann Sarkaria, Prahlad Ram, William Shapiro, Gordon Mills, Burt Feuerstein
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4138.
https://doi.org/10.1158/1538-7445.AM2011-4138
Published: 15 April 2011
View article titled, Abstract 4138: Five prognostic subgroups differ in expression of Akt pathway genes: Biomarkers for therapy selection
Journal Articles

Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in Braf-Mutant Human Cutaneous Melanoma Cells

Y.N. Vashisht Gopal, Wanleng Deng, Scott E. Woodman, Kakajan Komurov, Prahlad Ram, Paul D. Smith, Michael A. Davies
Journal: Cancer Research
Cancer Res (2010) 70 (21): 8736–8747.
https://doi.org/10.1158/0008-5472.CAN-10-0902
Published: 31 October 2010
View article titled, Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <em>Braf-</em>Mutant Human Cutaneous Melanoma Cells
Open the PDF for Basal and Treatment-Induced Activation of AKT Mediates Resistance to Cell Death by AZD6244 (ARRY-142886) in <em>Braf-</em>Mutant Human Cutaneous Melanoma Cells in another window
Includes: Supplementary data