1-20 of 42
Pnina Brodt
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

MICAL2 Promotes Pancreatic Cancer Growth and Metastasis

Bharti Garg, Sohini Khan, Asimina S. Courelli, Ponmathi Panneerpandian, Deepa Sheik Pran Babu, Evangeline S. Mose, Kevin Christian Montecillo Gulay, Shweta Sharma, Divya Sood, Alexander T. Wenzel, Alexei Martsinkovskiy, Nirakar Rajbhandari, Jay Patel, Dawn Jaquish, Edgar Esparza, Katelin Jaque, Neetu Aggarwal, Guillem Lambies, Anthony D’Ippolito, Kathryn Austgen, Brian Johnston, David A. Orlando, Gun Ho Jang, Steven Gallinger, Elliot Goodfellow, Pnina Brodt, Cosimo Commisso, Pablo Tamayo, Jill P. Mesirov, Hervé Tiriac, Andrew M. Lowy
Journal: Cancer Research
Cancer Res (2025) 85 (6): 1049–1063.
https://doi.org/10.1158/0008-5472.CAN-24-0744
Published: 14 March 2025
View articletitled, MICAL2 Promotes Pancreatic Cancer Growth and Metastasis
Open the PDF for MICAL2 Promotes Pancreatic Cancer Growth and Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract 4919: Estrogen regulates the immune microenvironment and immunotherapy response of colorectal liver metastases

Yasmine Benslimane, Sarah Lapin, Julien Chambon, Stephanie Perrino, Pnina Brodt
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 4919.
https://doi.org/10.1158/1538-7445.AM2023-4919
Published: 04 April 2023
View articletitled, Abstract 4919: Estrogen regulates the immune microenvironment and immunotherapy response of colorectal liver metastases
Journal Articles

Abstract 2515: Estrogen regulates the immune microenvironment of colorectal cancer liver metastases

Yasmine Benslimane, Sarah Lapin, Julien Chambon, Matthew Leibovitch, Stéphanie Perrino, Pnina Brodt
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2515.
https://doi.org/10.1158/1538-7445.AM2022-2515
Published: 15 June 2022
View articletitled, Abstract 2515: Estrogen regulates the immune microenvironment of colorectal cancer liver metastases
Journal Articles

Abstract 5076: Pancreatic ductal adenocarcinoma associated stellate cells promote a pro-metastatic microenvironment in the liver

John David Konda, Masakazu Hashimoto, Jian Zhang, Maria Celia Fernandez, Ni Wang, Stephanie Perrino, Laura Montermini, Janusz Rak, Jean-Sebastien Pelletier, Andrew M. Lowy, Pnina Brodt
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5076.
https://doi.org/10.1158/1538-7445.AM2018-5076
Published: 01 July 2018
View articletitled, Abstract 5076: Pancreatic ductal adenocarcinoma associated stellate cells promote a pro-metastatic microenvironment in the liver
Journal Articles

Abstract 2935: Sex disparity in the response of the immune microenvironment to colon cancer liver metastases

Simon Milette, Ni Wang, Stéphanie Perrino, Pnina Brodt
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 2935.
https://doi.org/10.1158/1538-7445.AM2017-2935
Published: 01 July 2017
View articletitled, Abstract 2935: Sex disparity in the response of the immune microenvironment to colon cancer liver metastases
Journal Articles

Abstract 5881: Identification of resistance mechanisms to IGF-IR targeting in triple negative breast cancer

Jennifer Tsui, George Vaniotis, Maria Celia Fernandez, Pnina Brodt
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5881.
https://doi.org/10.1158/1538-7445.AM2017-5881
Published: 01 July 2017
View articletitled, Abstract 5881: Identification of resistance mechanisms to IGF-IR targeting in triple negative breast cancer
Journal Articles

TNF Receptor-2 Facilitates an Immunosuppressive Microenvironment in the Liver to Promote the Colonization and Growth of Hepatic Metastases

Boram Ham, Ni Wang, Zarina D'Costa, Maria Celia Fernandez, France Bourdeau, Patrick Auguste, Martin Illemann, Rikke Loevendahl Eefsen, Gunilla Høyer-Hansen, Ben Vainer, Maximilien Evrard, Zu-Hua Gao, Pnina Brodt
Journal: Cancer Research
Cancer Res (2015) 75 (24): 5235–5247.
https://doi.org/10.1158/0008-5472.CAN-14-3173
Published: 14 December 2015
View articletitled, TNF Receptor-2 Facilitates an Immunosuppressive Microenvironment in the Liver to Promote the Colonization and Growth of Hepatic Metastases
Open the PDF for TNF Receptor-2 Facilitates an Immunosuppressive Microenvironment in the Liver to Promote the Colonization and Growth of Hepatic Metastases in another window
Includes: Supplementary data
Journal Articles

Abstract 5081: The IGF axis regulates hepatic stellate cell recruitment and activation during colorectal carcinoma liver metastasis

Maria C. Fernandez, Roni F. Rayes, Jun Xu, Tatiana Kisseleva, Shoshana Yakar, Pnina Brodt
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5081.
https://doi.org/10.1158/1538-7445.AM2015-5081
Published: 01 August 2015
View articletitled, Abstract 5081: The IGF axis regulates hepatic stellate cell recruitment and activation during colorectal carcinoma liver metastasis
Journal Articles

Abstract 2094: Regulation of site-specific liver metastasis by collagen IV-conveyed signals

Roni F. Rayes, Ni Wang, Julia V. Burnier, France Bourdeau, Pnina Brodt
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2094.
https://doi.org/10.1158/1538-7445.AM2014-2094
Published: 01 October 2014
View articletitled, Abstract 2094: Regulation of site-specific liver metastasis by collagen IV-conveyed signals
Journal Articles

Abstract 3305: Sustained production of a soluble IGF-I receptor by gutless adenovirus - transduced host cells protects from tumor growth in the liver .

Ni Wang, Yifan Lu, Amelie Pilotte, Maxime Pinard, Rénald Gilbert, Bernard Massie, Pnina Brodt
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3305.
https://doi.org/10.1158/1538-7445.AM2013-3305
Published: 15 April 2013
View articletitled, Abstract 3305: Sustained production of a soluble IGF-I receptor by gutless adenovirus - transduced host cells protects from tumor growth in the liver .
Journal Articles

The Multifaceted Role of the Microenvironment in Liver Metastasis: Biology and Clinical Implications

Gert G. Van den Eynden, Ali W. Majeed, Martin Illemann, Peter B. Vermeulen, Nigel C. Bird, Gunilla Høyer-Hansen, Rikke Løvendahl Eefsen, Andrew R. Reynolds, Pnina Brodt
Journal: Cancer Research
Cancer Res (2013) 73 (7): 2031–2043.
https://doi.org/10.1158/0008-5472.CAN-12-3931
Published: 02 April 2013
View articletitled, The Multifaceted Role of the Microenvironment in Liver Metastasis: Biology and Clinical Implications
Open the PDF for The Multifaceted Role of the Microenvironment in Liver Metastasis: Biology and Clinical Implications in another window
Includes: Supplementary data
Journal Articles

Abstract 1508: TNF-receptor 2 plays a critical role in liver metastasis by regulating sinusoidal endothelial VCAM-1 expression, LY6G+ leukocyte recruitment and transendothelial migration

Boram Ham, Patrick Auguste, Maximilien Evrard, Ni Wang, Yifan Lu, Pnina Brodt
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1508.
https://doi.org/10.1158/1538-7445.AM2012-1508
Published: 15 April 2012
View articletitled, Abstract 1508: TNF-receptor 2 plays a critical role in liver metastasis by regulating sinusoidal endothelial VCAM-1 expression, LY6G+ leukocyte recruitment and transendothelial migration
Journal Articles

Metastatic Cells Can Escape the Proapoptotic Effects of TNF-α through Increased Autocrine IL-6/STAT3 Signaling

Shun Li, Ni Wang, Pnina Brodt
Journal: Cancer Research
Cancer Res (2012) 72 (4): 865–875.
https://doi.org/10.1158/0008-5472.CAN-11-1357
Published: 14 February 2012
View articletitled, Metastatic Cells Can Escape the Proapoptotic Effects of TNF-α through Increased Autocrine IL-6/STAT3 Signaling
Open the PDF for Metastatic Cells Can Escape the Proapoptotic Effects of TNF-α through Increased Autocrine IL-6/STAT3 Signaling in another window
Includes: Supplementary data
Journal Articles

Abstract 5255: The role of IGF1 signaling in site specific tumor metastasis: Regulating matrix metalloproteinase (MMP) expression

Erica Seccareccia, Shun Li, Pnina Brodt
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5255.
https://doi.org/10.1158/1538-7445.AM2011-5255
Published: 15 April 2011
View articletitled, Abstract 5255: The role of IGF1 signaling in site specific tumor metastasis: Regulating matrix metalloproteinase (MMP) expression
Journal Articles

Abstract 554: Crosstalk between TNF-α and IGF signalling increases IL-6 production and protects tumor cells from TNF-α-induced apoptosis in the liver

Shun Li, Long Yang, Rongtuan Lin, John Hiscott, Pnina Brodt
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 554.
https://doi.org/10.1158/1538-7445.AM10-554
Published: 15 April 2010
View articletitled, Abstract 554: Crosstalk between TNF-α and IGF signalling increases IL-6 production and protects tumor cells from TNF-α-induced apoptosis in the liver
Journal Articles

Abstract 5172: Role of CEACAM1 on cancer cell endothelial adhesion and liver metastasis in vivo

Carlos H.F. Chan, Azadeh Arabzadeh, Luisa DeMarte, Jonathan Spicer, Claire Turbide, Pnina Brodt, Nicole Beauchemin, Lorenzo E. Ferri
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 5172.
https://doi.org/10.1158/1538-7445.AM10-5172
Published: 15 April 2010
View articletitled, Abstract 5172: Role of CEACAM1 on cancer cell endothelial adhesion and liver metastasis in vivo
Journal Articles

Insulin-Like Growth Factor-I Regulates the Liver Microenvironment in Obese Mice and Promotes Liver Metastasis

Yingjie Wu, Pnina Brodt, Hui Sun, Wilson Mejia, Ruslan Novosyadlyy, Nomeli Nunez, Xiaoli Chen, Arnulfo Mendoza, Sung-Hyeok Hong, Chand Khanna, Shoshana Yakar
Journal: Cancer Research
Cancer Res (2010) 70 (1): 57–67.
https://doi.org/10.1158/0008-5472.CAN-09-2472
Published: 04 January 2010
View articletitled, Insulin-Like Growth Factor-I Regulates the Liver Microenvironment in Obese Mice and Promotes Liver Metastasis
Open the PDF for Insulin-Like Growth Factor-I Regulates the Liver Microenvironment in Obese Mice and Promotes Liver Metastasis in another window
Includes: Supplementary data
Journal Articles

Abstract #4974: Collagen IV expression levels are a critical determinant of liver metastasis.

Julia Burnier, Ni Wang, Emilia Antecka, Rene Michel, Mazen Hassanain, Peter Metrakos, Miguel Burnier, Steve Gallinger, Pnina Brodt
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 4974.
Published: 01 May 2009
View articletitled, Abstract #4974: Collagen IV expression levels are a critical determinant of liver metastasis.
Journal Articles

Abstract #5276: Overexpression of the IGF-I receptor alters the metastatic properties of tumor cells by regulating of their cytokine profiles: role of NF-\#954;B signaling.

Shun Li, Long Yang, Rongtuan Lin, John Hiscott, Pnina Brodt
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5276.
Published: 01 May 2009
View articletitled, Abstract #5276: Overexpression of the IGF-I receptor alters the metastatic properties of tumor cells by regulating of their cytokine profiles: role of NF-\#954;B signaling.
Journal Articles

Regulation of PKC-α and PMA-inducible metalloproteinases by the IGF-I receptor

Shun Li, Donglei Zhang, Long Yang, Ni Wang, Rongtuan Lin, Pnina Brodt
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3414.
Published: 01 May 2008
View articletitled, Regulation of PKC-α and PMA-inducible metalloproteinases by the IGF-I receptor