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Journal Articles

Abstract 5518: Targeting FAK by Ifebemtinib synergizes with Pan RAS inhibitors in treating RAS mutant cancers

Free
Baoyuan Zhang, Ran Pang, Jiaming Gao, Jingwen Cheng, Ping Zhang, Natasha Qin, Leo Liu, Zaiqi Wang
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5518.
https://doi.org/10.1158/1538-7445.AM2025-5518
Published: 21 April 2025
View articletitled, Abstract 5518: Targeting FAK by Ifebemtinib synergizes with Pan RAS inhibitors in treating RAS mutant cancers
Journal Articles

B7-H3–Targeted CAR-Vδ1T Cells Exhibit Potent Broad-Spectrum Activity against Solid Tumors

Open Access
Licui Jiang, Fengtao You, Hai Wu, Changsong Qi, Shufen Xiang, Ping Zhang, Huimin Meng, Min Wang, Jiequn Huang, Yafen Li, Dan Chen, Gangli An, Nan Yang, Bozhen Zhang, Lin Shen, Lin Yang
Journal: Cancer Research
Cancer Res (2024) 84 (23): 4066–4080.
https://doi.org/10.1158/0008-5472.CAN-24-0195
Published: 02 December 2024
View articletitled, B7-H3–Targeted CAR-Vδ1T Cells Exhibit Potent Broad-Spectrum Activity against Solid Tumors
Open the PDF for B7-H3–Targeted CAR-Vδ1T Cells Exhibit Potent Broad-Spectrum Activity against Solid Tumors in another window
Includes: Supplementary data
Journal Articles

Abstract 5254: The “off-the-shelf ”CD19-CAR-Vδ1T cells demonstrated an enhanced therapeutic effect on B-cell malignancy models

Free
Dan Chen, Fengtao You, Cheng Chen, Shufen Xiang, Ping Zhang, Hai Wu, Zhong Zheng, Min Wang, Xingbing Wang, Huimin Meng, Nan Yang, Bozhen Zhang, Lin Yang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5254.
https://doi.org/10.1158/1538-7445.AM2024-5254
Published: 22 March 2024
View articletitled, Abstract 5254: The “off-the-shelf ”CD19-CAR-Vδ1T cells demonstrated an enhanced therapeutic effect on B-cell malignancy models
Journal Articles

Abstract 5255: A B7-H3-CAR-modified Vδ1 T cells showed potentanti-solid tumor potential

Free
Licui Jiang, Changsong Qi, Fengtao You, Shufen Xiang, Ping Zhang, Min Wang, Hai Wu, Kunmin Yan, Jiequn Huang, Huimin Meng, Nan Yang, Shirley Zhang, Lin Shen, Lin Yang
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5255.
https://doi.org/10.1158/1538-7445.AM2024-5255
Published: 22 March 2024
View articletitled, Abstract 5255: A B7-H3-CAR-modified Vδ1 T cells showed potentanti-solid tumor potential
Journal Articles

Abstract 3502: AXA-042 - a novel systemic TLR2/6 agonist for anti-tumor therapy

Free
Anna V. Galkin, Francesca Mercuri, Nicholas West, Ping Zhang, Weiguang Zeng, Grant McLachlan, Michael Bettess, Ian Holmes, David Jackson, Chris Smith, Christophe Demaison, Tobias Bald, Phil Kearney
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 3502.
https://doi.org/10.1158/1538-7445.AM2022-3502
Published: 15 June 2022
View articletitled, Abstract 3502: AXA-042 - a novel systemic TLR2/6 agonist for anti-tumor therapy
Journal Articles

Abstract 2492: Association of TP53 and LRP1B co-mutation status with response to immunotherapy in lung squamous cell carcinoma

Free
Jiangyong Yu, Zhipeng Zhou, Ping Zhang, Pansong Li, Xu Li, Min Tang, Nannan Fan, Xiaonan Wu, Xin Nie, Xiaoyan Chen, Di Ma, Xi Chen, Yanfang Guan, Xuefeng Xia, Ling Yang, Xin Yi, Lin Li
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2492.
https://doi.org/10.1158/1538-7445.AM2021-2492
Published: 01 July 2021
View articletitled, Abstract 2492: Association of TP53 and LRP1B co-mutation status with response to immunotherapy in lung squamous cell carcinoma
Journal Articles

Abstract 280: Sub-30-nm capsules for drug delivery

Free
Xiaowei Ma, Ping Zhang, Chao Cui, Chang-Chun Ling, Lina Cui
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 280.
https://doi.org/10.1158/1538-7445.AM2021-280
Published: 01 July 2021
View articletitled, Abstract 280: Sub-30-nm capsules for drug delivery
Journal Articles

Abstract 1861: Advancing bispecific antibody discovery using common light chain immunoglobulin humanized mouse

Free
Li Hui, Hui Lu, Yabo Zhang, Shuwen Huang, Ping Zhang, Huizhen Zhao, Ruifang Chang, Bing Yang, Fengqian Zhang, Wendong Yang, Fang Yang, Hao Yang, Jiawei Yao, Lei Chen, Qingcong Lin
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1861.
https://doi.org/10.1158/1538-7445.AM2021-1861
Published: 01 July 2021
View articletitled, Abstract 1861: Advancing bispecific antibody discovery using common light chain immunoglobulin humanized mouse
Journal Articles

Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response

Available to Purchase
Ping Zhang, Isaac Kitchen-Smith, Lingyun Xiong, Giovanni Stracquadanio, Katherine Brown, Philipp H. Richter, Marsha D. Wallace, Elisabeth Bond, Natasha Sahgal, Samantha Moore, Svanhild Nornes, Sarah De Val, Mirvat Surakhy, David Sims, Xuting Wang, Douglas A. Bell, Jorge Zeron-Medina, Yanyan Jiang, Anderson J. Ryan, Joanna L. Selfe, Janet Shipley, Siddhartha Kar, Paul D. Pharoah, Chey Loveday, Rick Jansen, Lukasz F. Grochola, Claire Palles, Andrew Protheroe, Val Millar, Daniel V. Ebner, Meghana Pagadala, Sarah P. Blagden, Timothy S. Maughan, Enric Domingo, Ian Tomlinson, Clare Turnbull, Hannah Carter, Gareth L. Bond
Journal: Cancer Research
Cancer Res (2021) 81 (7): 1667–1680.
https://doi.org/10.1158/0008-5472.CAN-20-0177
Published: 01 April 2021
View articletitled, Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response
Open the PDF for Germline and Somatic Genetic Variants in the p53 Pathway Interact to Affect Cancer Risk, Progression, and Drug Response in another window
Includes: Supplementary data
Journal Articles

Abstract 2550: Lack of FGF21 accelerates NASH-HCC transition via up-regulation of hepatic SPHK1-S1P-HIPPO signaling in murine models

Free
Xiaoju Shi, Robert C. Martin, Youxi Yu, Yujia Chen, Xingtong Wang, Guangyi Wang, Guoyue Lv, Ping Zhang, Yan Li
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 2550.
https://doi.org/10.1158/1538-7445.AM2020-2550
Published: 15 August 2020
View articletitled, Abstract 2550: Lack of FGF21 accelerates NASH-HCC transition via up-regulation of hepatic SPHK1-S1P-HIPPO signaling in murine models
Journal Articles

Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides

Free
Minle Li, Ying Lu, Yakui Li, Lingfeng Tong, Xiao-chuan Gu, Jian Meng, Yemin Zhu, Lifang Wu, Ming Feng, Na Tian, Ping Zhang, Tianle Xu, Shu-Hai Lin, Xuemei Tong
Journal: Cancer Research
Cancer Res (2019) 79 (14): 3689–3701.
https://doi.org/10.1158/0008-5472.CAN-18-3776
Published: 15 July 2019
View articletitled, Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides
Open the PDF for Transketolase Deficiency Protects the Liver from DNA Damage by Increasing Levels of Ribose 5-Phosphate and Nucleotides in another window
Includes: Supplementary data
Journal Articles

Abstract 3225: Enhancement of anti-PD1 and anti-CTLA4 efficacy by NBTXR3 nanoparticles exposed to radiotherapy

Free
Yun Hu, Ping Zhang, Audrey Darmon, Maria Angelica Cortez, Sébastien Paris, James Welsh
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3225.
https://doi.org/10.1158/1538-7445.AM2019-3225
Published: 01 July 2019
View articletitled, Abstract 3225: Enhancement of anti-PD1 and anti-CTLA4 efficacy by NBTXR3 nanoparticles exposed to radiotherapy
Journal Articles

Abstract 4373: Lack of FGF21 promotes NASH-HCC transition via exosome-mediated carcinogenetic signaling

Free
Youxi Yu, Robert C. Martin, Qianqian Zheng, Xiaoju Shi, Xingkai Liu, Wei Guo, Suping Li, Ping Zhang, Yan Li
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4373.
https://doi.org/10.1158/1538-7445.AM2019-4373
Published: 01 July 2019
View articletitled, Abstract 4373: Lack of FGF21 promotes NASH-HCC transition via exosome-mediated carcinogenetic signaling
Journal Articles

Abstract LB-255: Acquired and intrinsic resistance to vemurafenib in BRAFv600e-driven melanoma brain metastases

Free
Mark C. de Gooijer, Ping Zhang, Levi C. Buil, Stephan Freriks, Gang Li, Jos H. Beijnen, Olaf Van Tellingen
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-255.
https://doi.org/10.1158/1538-7445.AM2019-LB-255
Published: 01 July 2019
View articletitled, Abstract LB-255: Acquired and intrinsic resistance to vemurafenib in BRAFv600e-driven melanoma brain metastases
Journal Articles

Abstract 4571: Activation of the cGAS-STING pathway by NBTXR3 nanoparticles exposed to radiotherapy

Free
Julie Marill, Naeemunnisa Mohamed Anesary, Audrey Darmon, Ping Zhang, Sébastien Paris
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4571.
https://doi.org/10.1158/1538-7445.AM2018-4571
Published: 01 July 2018
View articletitled, Abstract 4571: Activation of the cGAS-STING pathway by NBTXR3 nanoparticles exposed to radiotherapy
Journal Articles

hPCL3s Promotes Hepatocellular Carcinoma Metastasis by Activating β-Catenin Signaling

Free
Zhen Cai, Zhen-Yu Qian, Hao Jiang, Ning Ma, Zhi Li, Li-Yu Liu, Xin-Xin Ren, Yu-Rong Shang, Jing-Jing Wang, Jing-Jing Li, Dong-Ping Liu, Xiu-Ping Zhang, Dan Feng, Qian-Zhi Ni, Yuan-Yuan Feng, Nan Li, Xiao-Yan Zhou, Xiang Wang, Ying Bao, Xue-Li Zhang, Yue-Zhen Deng, Dong Xie
Journal: Cancer Research
Cancer Res (2018) 78 (10): 2536–2549.
https://doi.org/10.1158/0008-5472.CAN-17-0028
Published: 14 May 2018
View articletitled, hPCL3s Promotes Hepatocellular Carcinoma Metastasis by Activating β-Catenin Signaling
Open the PDF for hPCL3s Promotes Hepatocellular Carcinoma Metastasis by Activating β-Catenin Signaling in another window
Includes: Supplementary data
Journal Articles

JCAD Promotes Progression of Nonalcoholic Steatohepatitis to Liver Cancer by Inhibiting LATS2 Kinase Activity

Free
Juan Ye, Tian-Sheng Li, Gang Xu, Yi-Ming Zhao, Ning-Ping Zhang, Jia Fan, Jian Wu
Journal: Cancer Research
Cancer Res (2017) 77 (19): 5287–5300.
https://doi.org/10.1158/0008-5472.CAN-17-0229
Published: 01 October 2017
View articletitled, JCAD Promotes Progression of Nonalcoholic Steatohepatitis to Liver Cancer by Inhibiting LATS2 Kinase Activity
Open the PDF for JCAD Promotes Progression of Nonalcoholic Steatohepatitis to Liver Cancer by Inhibiting LATS2 Kinase Activity in another window
Includes: Supplementary data
Journal Articles

Abstract 1603: NKTR-255 engages the IL-15 pathway driving CD8 T cell survival and CD8 memory T cell proliferation

Free
Peiwen Kuo, Mekhala Maiti, Phi Quach, Murali Addepalli, Arunasree Lanka, Poornachandra Mathamsetti, Christie Fanton, Ping Zhang, Peter Kirk, Takahiro Miyazaki, Jonathan Zalevsky
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 1603.
https://doi.org/10.1158/1538-7445.AM2017-1603
Published: 01 July 2017
View articletitled, Abstract 1603: NKTR-255 engages the IL-15 pathway driving CD8 T cell survival and CD8 memory T cell proliferation
Journal Articles

Abstract 5193: Hafnium oxide nanoparticles (NBTXR3), a novel radiation enhancer achieves marked antitumor efficacy across five tumor types

Free
Ping Zhang, Sonia Vivet, Sébastien Paris, Agnès Pottier
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5193.
https://doi.org/10.1158/1538-7445.AM2017-5193
Published: 01 July 2017
View articletitled, Abstract 5193: Hafnium oxide nanoparticles (NBTXR3), a novel radiation enhancer achieves marked antitumor efficacy across five tumor types
Journal Articles

Abstract 4734: Inhibitory effects of metformin on epithelial-mesenchymal transition of CD44+/CD117+ ovarian cancer stem cells

Free
Gary G. Xiao, Rongrong Zhang, Ping Zhang, Hong Wang, Dongming Hou, Wentao Li, Chenwei Li
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4734.
https://doi.org/10.1158/1538-7445.AM2016-4734
Published: 15 July 2016
View articletitled, Abstract 4734: Inhibitory effects of metformin on epithelial-mesenchymal transition of CD44+/CD117+ ovarian cancer stem cells