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Pinar Ormanoglu
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Journal Articles

Abstract 605: Linkage of NF-κB pathway and mitosis-related molecules using integrated RNAi screening and transcriptomic analysis of head and neck squamous cell carcinoma

Jun W. Jeon, Anthony D. Saleh, Shaleeka Cornelius, Sophie Carlson, Scott Martin, Pinar Ormanoglu, Hui Cheng, Xinping Yang, Chris Silvin, Zhong Chen, Carter Van Waes
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 605.
https://doi.org/10.1158/1538-7445.AM2020-605
Published: 15 August 2020
View article titled, Abstract 605: Linkage of NF-κB pathway and mitosis-related molecules using integrated RNAi screening and transcriptomic analysis of head and neck squamous cell carcinoma
Journal Articles

Abstract 2988: Integrated functional RNAi screening and structural genomics identify cell cycle and kinetochore components co-modulating NF-κB activity as potential therapeutic targets in head and neck squamous cell carcinoma

Anthony D. Saleh, Sophie Carlson, Shaleeka Cornelius, Hui Cheng, Scott Martin, Pinar Ormanoglu
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2988.
https://doi.org/10.1158/1538-7445.AM2016-2988
Published: 15 July 2016
View article titled, Abstract 2988: Integrated functional RNAi screening and structural genomics identify cell cycle and kinetochore components co-modulating NF-κB activity as potential therapeutic targets in head and neck squamous cell carcinoma
Journal Articles

Abstract 743: Tyrosine kinase discoidin domain receptor-1 (DDR1) regulates cytotoxicity of recombinant immunotoxin for cancer therapy

Fatima Ali-Rahmani, David Fitzgerald, Scott Martin, Paresma Patel, Marco Prunotto, Pinar Ormanoglu, Craig Thomas, Ira Pastan
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 743.
https://doi.org/10.1158/1538-7445.AM2016-743
Published: 15 July 2016
View article titled, Abstract 743: Tyrosine kinase discoidin domain receptor-1 (DDR1) regulates cytotoxicity of recombinant immunotoxin for cancer therapy
Journal Articles

Abstract B31: Combined siRNA and small molecule screening identifies Aurora B kinase as an effective target in MYCN-driven neuroblastoma

Dominik Bogen, Jun S. Wei, David O. Azorsa, Pinar Ormanoglu, Eugen Buehler, Rajarshi Guha, Jonathan M. Keller, Lesley A. Mathews Griner, Marc Ferrer, Young K. Song, Hongling Liao, Arnulfo Mendoza, Berkley E. Gryder, Sivasish Sindri, Jianbin He, Xinyu Wen, Xinyu Wen, Shile Zhang, John F. Shern, Marielle E. Yohe, Sabine Taschner-Mandl, Jason Shohet, Craig J. Thomas, Scott E. Martin, Peter F. Ambros, Javed Khan
Journal: Cancer Research
Cancer Res (2016) 76 (5_Supplement): B31.
https://doi.org/10.1158/1538-7445.PEDCA15-B31
Published: 04 April 2016
View article titled, Abstract B31: Combined siRNA and small molecule screening identifies Aurora B kinase as an effective target in MYCN-driven neuroblastoma
Journal Articles

Anticancer Effects of Mesothelin-Targeted Immunotoxin Therapy Are Regulated by Tyrosine Kinase DDR1

Fatima Ali-Rahmani, David J. FitzGerald, Scott Martin, Paresma Patel, Marco Prunotto, Pinar Ormanoglu, Craig Thomas, Ira Pastan
Journal: Cancer Research
Cancer Res (2016) 76 (6): 1560–1568.
https://doi.org/10.1158/0008-5472.CAN-15-2401
Published: 14 March 2016
View article titled, Anticancer Effects of Mesothelin-Targeted Immunotoxin Therapy Are Regulated by Tyrosine Kinase DDR1
Open the PDF for Anticancer Effects of Mesothelin-Targeted Immunotoxin Therapy Are Regulated by Tyrosine Kinase DDR1 in another window
Includes: Supplementary data
Journal Articles

Abstract 1724: Integrated functional RNAi screening and structural genomics identify inverse co-modulators of TP53 family and NF-κB transitional activation as potential therapeutic targets in head and neck squamous cell carcinoma

Anthony Saleh, Shaleeka Cornelius, Scott Martin, Pinar Ormanoglu, Hui Cheng, Rita Das, Xinping Yang, Zhong Chen, Carter Van Waes
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 1724.
https://doi.org/10.1158/1538-7445.AM2015-1724
Published: 01 August 2015
View article titled, Abstract 1724: Integrated functional RNAi screening and structural genomics identify inverse co-modulators of TP53 family and NF-κB transitional activation as potential therapeutic targets in head and neck squamous cell carcinoma
Journal Articles

ATR Inhibitors VE-821 and VX-970 Sensitize Cancer Cells to Topoisomerase I Inhibitors by Disabling DNA Replication Initiation and Fork Elongation Responses

Rozenn Jossé, Scott E. Martin, Rajarshi Guha, Pinar Ormanoglu, Thomas D. Pfister, Philip M. Reaper, Christopher S. Barnes, Julie Jones, Peter Charlton, John R. Pollard, Joel Morris, James H. Doroshow, Yves Pommier
Journal: Cancer Research
Cancer Res (2014) 74 (23): 6968–6979.
https://doi.org/10.1158/0008-5472.CAN-13-3369
Published: 30 November 2014
View article titled, ATR Inhibitors VE-821 and VX-970 Sensitize Cancer Cells to Topoisomerase I Inhibitors by Disabling DNA Replication Initiation and Fork Elongation Responses
Open the PDF for ATR Inhibitors VE-821 and VX-970 Sensitize Cancer Cells to Topoisomerase I Inhibitors by Disabling DNA Replication Initiation and Fork Elongation Responses in another window
Includes: Supplementary data
Journal Articles

Abstract 794: The ATR inhibitor VE-821 in combination with the novel topoisomerase I inhibitor LMP-400 selectively kills cancer cells by disabling DNA replication initiation and fork elongation

Rozenn Jossé, Scott E. Martin, Rajarshi Guha, Pinar Ormanoglu, Thomas Pfister, Joel Morris, James H. Doroshow, Yves Pommier
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 794.
https://doi.org/10.1158/1538-7445.AM2014-794
Published: 01 October 2014
View article titled, Abstract 794: The ATR inhibitor VE-821 in combination with the novel topoisomerase I inhibitor LMP-400 selectively kills cancer cells by disabling DNA replication initiation and fork elongation
Journal Articles

Abstract 3400: Integrated functional RNAi screening and structural genomics identifies inverse co-modulators of TP53 family and NF-kB transitional activation as potential therapeutic targets in head and neck squamous cell carcinoma

Anthony D. Saleh, Shaleeka Cornelius, Hui Cheng, Scott Martin, Pinar Ormanoglu, Xinping Yang, Zhong Chen, Carter VanWaes
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3400.
https://doi.org/10.1158/1538-7445.AM2014-3400
Published: 01 October 2014
View article titled, Abstract 3400: Integrated functional RNAi screening and structural genomics identifies inverse co-modulators of TP53 family and NF-kB transitional activation as potential therapeutic targets in head and neck squamous cell carcinoma