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Pierre van der Bruggen
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Journal Articles

A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability

Guido Leoni, Anna Morena D'Alise, Gabriella Cotugno, Francesca Langone, Irene Garzia, Maria De Lucia, Imma Fichera, Rosa Vitale, Veronica Bignone, Fabio Giovanni Tucci, Federica Mori, Adriano Leuzzi, Elena Di Matteo, Fulvia Troise, Adele Abbate, Rossella Merone, Valentino Ruzza, Maria Grazia Diodoro, Mahesh Yadav, Monica Gordon-Alonso, Cristophe Vanhaver, Maddalena Panigada, Elisa Soprana, Antonio Siccardi, Antonella Folgori, Stefano Colloca, Pierre van der Bruggen, Alfredo Nicosia, Armin Lahm, Maria Teresa Catanese, Elisa Scarselli
Journal: Cancer Research
Cancer Res (2020) 80 (18): 3972–3982.
https://doi.org/10.1158/0008-5472.CAN-20-1072
Published: 15 September 2020
View article titled, A Genetic Vaccine Encoding Shared Cancer Neoantigens to Treat Tumors with Microsatellite Instability
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Includes: Supplementary data
Journal Articles

Abstract CT003: A phase I study of an HLA-DPB1*0401-restricted T-cell receptor targeting MAGE-A3 for patients with metastatic cancer

Yong-Chen Lu, Linda L. Parker, Tangying Lu, Zhili Zheng, Xin Yao, Paul F. Robbins, Steven A. Feldman, Pierre van der Bruggen, Christopher A. Klebanoff, Christian S. Hinrichs, Stephanie L. Goff, Richard M. Sherry, Udai S. Kammula, James C. Yang, Steven A. Rosenberg
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): CT003.
https://doi.org/10.1158/1538-7445.AM2016-CT003
Published: 15 July 2016
View article titled, Abstract CT003: A phase I study of an HLA-DPB1*0401-restricted T-cell receptor targeting MAGE-A3 for patients with metastatic cancer
Journal Articles

A Galectin-3 Ligand Corrects the Impaired Function of Human CD4 and CD8 Tumor-Infiltrating Lymphocytes and Favors Tumor Rejection in Mice

Nathalie Demotte, Grégoire Wieërs, Patrick Van Der Smissen, Muriel Moser, Christopher Schmidt, Kris Thielemans, Jean-Luc Squifflet, Birgit Weynand, Javier Carrasco, Christophe Lurquin, Pierre J. Courtoy, Pierre van der Bruggen
Journal: Cancer Research
Cancer Res (2010) 70 (19): 7476–7488.
https://doi.org/10.1158/0008-5472.CAN-10-0761
Published: 29 September 2010
View article titled, A Galectin-3 Ligand Corrects the Impaired Function of Human CD4 and CD8 Tumor-Infiltrating Lymphocytes and Favors Tumor Rejection in Mice
Open the PDF for A Galectin-3 Ligand Corrects the Impaired Function of Human CD4 and CD8 Tumor-Infiltrating Lymphocytes and Favors Tumor Rejection in Mice in another window
Includes: Supplementary data
Journal Articles

The CD4+ T-Cell Response of Melanoma Patients to a MAGE-A3 Peptide Vaccine Involves Potential Regulatory T Cells

Violaine François, Sabrina Ottaviani, Nicolina Renkvist, Julie Stockis, Gerold Schuler, Kris Thielemans, Didier Colau, Marie Marchand, Thierry Boon, Sophie Lucas, Pierre van der Bruggen
Journal: Cancer Research
Cancer Res (2009) 69 (10): 4335–4345.
https://doi.org/10.1158/0008-5472.CAN-08-3726
Published: 15 May 2009
View article titled, The CD4<sup>+</sup> T-Cell Response of Melanoma Patients to a MAGE-A3 Peptide Vaccine Involves Potential Regulatory T Cells
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Includes: Supplementary data
Journal Articles

Efficient Presentation of Known HLA Class II-restricted MAGE-A3 Epitopes by Dendritic Cells Electroporated with Messenger RNA Encoding an Invariant Chain with Genetic Exchange of Class II-associated Invariant Chain Peptide

Aude Bonehill, Carlo Heirman, Sandra Tuyaerts, Annelies Michiels, Yi Zhang, Pierre van der Bruggen, Kris Thielemans
Journal: Cancer Research
Cancer Res (2003) 63 (17): 5587–5594.
Published: 18 September 2003
View article titled, Efficient Presentation of Known HLA Class II-restricted MAGE-A3 Epitopes by Dendritic Cells Electroporated with Messenger RNA Encoding an Invariant Chain with Genetic Exchange of Class II-associated Invariant Chain Peptide
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Journal Articles

A Retrogen Strategy for Presentation of an Intracellular Tumor Antigen as an Exogenous Antigen by Dendritic Cells Induces Potent Antitumor T Helper and CTL Responses

Zhaoyang You, Jenny Hester, Lisa Rollins, Giulio C. Spagnoli, Pierre van der Bruggen, Si-Yi Chen
Journal: Cancer Research
Cancer Res (2001) 61 (1): 197–205.
Published: 01 January 2001
View article titled, A Retrogen Strategy for Presentation of an Intracellular Tumor Antigen as an Exogenous Antigen by Dendritic Cells Induces Potent Antitumor T Helper and CTL Responses
Open the PDF for A Retrogen Strategy for Presentation of an Intracellular Tumor Antigen as an Exogenous Antigen by Dendritic Cells Induces Potent Antitumor T Helper and CTL Responses in another window
Journal Articles

A MAGE-A3 Peptide Presented by HLA-DP4 Is Recognized on Tumor Cells by CD4+ Cytolytic T Lymphocytes

Erwin S. Schultz, Bernard Lethé, César L. Cambiaso, Jacques Van Snick, Pascal Chaux, Jurgen Corthals, Carlo Heirman, Kris Thielemans, Thierry Boon, Pierre van der Bruggen
Journal: Cancer Research
Cancer Res (2000) 60 (22): 6272–6275.
Published: 15 November 2000
View article titled, A MAGE-A3 Peptide Presented by HLA-DP4 Is Recognized on Tumor Cells by CD4<sup>+</sup> Cytolytic T Lymphocytes
Open the PDF for A MAGE-A3 Peptide Presented by HLA-DP4 Is Recognized on Tumor Cells by CD4<sup>+</sup> Cytolytic T Lymphocytes in another window
Journal Articles

Characterization of the GAGE Genes That Are Expressed in Various Human Cancers and in Normal Testis

Olivier De Backer, Karen C. Arden, Mauro Boretti, Valérie Vantomme, Charles De Smet, Suzanne Czekay, Carrie S. Viars, Etienne De Plaen, Francis Brasseur, Patrick Chomez, Benoît Van den Eynde, Thierry Boon, Pierre van der Bruggen
Journal: Cancer Research
Cancer Res (1999) 59 (13): 3157–3165.
Published: 01 July 1999
View article titled, Characterization of the <em>GAGE</em> Genes That Are Expressed in Various Human Cancers and in Normal Testis
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Journal Articles

Stimulation of CD40 on Immunogenic Human Malignant Melanomas Augments Their Cytotoxic T Lymphocyte-mediated Lysis and Induces Apoptosis

Achim von Leoprechting, Pierre van der Bruggen, Heike L. Pahl, Alejandro Aruffo, Jan C. Simon
Journal: Cancer Research
Cancer Res (1999) 59 (6): 1287–1294.
Published: 15 March 1999
View article titled, Stimulation of CD40 on Immunogenic Human Malignant Melanomas Augments Their Cytotoxic T Lymphocyte-mediated Lysis and Induces Apoptosis
Open the PDF for Stimulation of CD40 on Immunogenic Human Malignant Melanomas Augments Their Cytotoxic T Lymphocyte-mediated Lysis and Induces Apoptosis in another window