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Pierre Laurent-Puig
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Journal Articles

Abstract 3654: Comparative efficacy of FOLFIRINOX versus gemcitabine plus nab-paclitaxel in metastatic pancreatic cancer: computing IPTW estimator while limiting patient data exposure with federated learning across 3 institutions

Free
Quentin Klopfenstein, Jean Ogier du Terrail, Honghao Li, Imke Mayer, Nicolas Loiseau, Mohammad Hallal, Michael Debouver, Thibault Camalon, Thibault Fouqueray, Jorge Arellano Castro, Zahia Yanes, Laëtitia Dahan, Julien Taïeb, Pierre Laurent-Puig, Jean-Baptiste Bachet, Shulin Zhao, Remy Nicolle, Jérôme Cros, Daniel Gonzalez, Robert Carreras-Torres, Adelaida Garcia Velasco, Kawther Abdilleh, Sudheer Doss, Félix Balazard, Mathieu Andreux
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 3654.
https://doi.org/10.1158/1538-7445.AM2025-3654
Published: 21 April 2025
View article titled, Abstract 3654: Comparative efficacy of FOLFIRINOX versus gemcitabine plus nab-paclitaxel in metastatic pancreatic cancer: computing IPTW estimator while limiting patient data exposure with federated learning across 3 institutions
Journal Articles

Abstract 5430: Improved colorectal cancer survival prediction with deep learning-based WSI analysis on PETACC8 and PRODIGE13 cohorts

Free
Jean-Eudes Le Douget, Julien Taïeb, Paul Jacob, Frédéric Bibeau, Karine Le Malicot, Jean-François Emile, Aurélien de Reyniès, Mehdi Morel, Simon Jégou, Côme Lepage, Pierre Laurent-Puig
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5430.
https://doi.org/10.1158/1538-7445.AM2023-5430
Published: 04 April 2023
View article titled, Abstract 5430: Improved colorectal cancer survival prediction with deep learning-based WSI analysis on PETACC8 and PRODIGE13 cohorts
Journal Articles

Deciphering the Role of Intestinal Crypt Cell Populations in Resistance to Chemotherapy

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Carla Frau, Catherine Jamard, Gaspard Delpouve, Gabriela D.A. Guardia, Christelle Machon, Camilla Pilati, Clémentine Le Nevé, Pierre Laurent-Puig, Jérôme Guitton, Pedro A.F. Galante, Luiz O. Penalva, Jean-Noel Freund, Christelle de la Fouchardiere, Michelina Plateroti
Journal: Cancer Research
Cancer Res (2021) 81 (10): 2730–2744.
https://doi.org/10.1158/0008-5472.CAN-20-2450
Published: 15 May 2021
View article titled, Deciphering the Role of Intestinal Crypt Cell Populations in Resistance to Chemotherapy
Open the PDF for Deciphering the Role of Intestinal Crypt Cell Populations in Resistance to Chemotherapy in another window
Includes: Supplementary data
Journal Articles

Abstract LB-088: Exploratory multiplex tissue image analysis of the impact of heterogeneity in the microenvironment of primary colorectal cancer on apoptosis markers in patients

Free
Andreas Urlich Lindner, Manuela Salvucci, Xanthi Stachtea, Steven Carberry, Philip D. Dunne, Anup Sood, Elizabeth McDonough, Sanghee Cho, Pierre Laurent-Puig, Sandra Van Schaeybroeck, Manuel Salto-Tellez, John F. Graf, Markus Rehm, Mark Lawler, Daniel B. Longley, Fiona Ginty Fiona, Jochen H. Prehn
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-088.
https://doi.org/10.1158/1538-7445.AM2019-LB-088
Published: 01 July 2019
View article titled, Abstract LB-088: Exploratory multiplex tissue image analysis of the impact of heterogeneity in the microenvironment of primary colorectal cancer on apoptosis markers in patients
Journal Articles

Abstract 4955: Impact of PD-1, PD-L1 and EBI3 on prognosis in a cohort of localized high grade undifferentiated pleomorphic sarcoma patients

Free
Pascaline Boudou-Rouquette, Anne Jouinot, Virginie Audard, Franck Letourneur, Béatrice Parfait, François Goldwasser, Benoit Terris, Pierre Laurent-Puig, Jérôme Alexandre, Karen Leroy, Eric Pasmant, Odile Devergne, Frederique Larousserie
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 4955.
https://doi.org/10.1158/1538-7445.AM2019-4955
Published: 01 July 2019
View article titled, Abstract 4955: Impact of PD-1, PD-L1 and EBI3 on prognosis in a cohort of localized high grade undifferentiated pleomorphic sarcoma patients
Journal Articles

Abstract 573: Mutations found by targeted next generation sequencing is associated with intra-tumor immune profile and may predict response to anti-PD1 therapy in lung adenocarcinoma

Free
Audrey Lupo, Jerome Biton, Marco Alifano, Diane Damotte, Jennifer Arrondeau, Pascaline Boudou, François Goldwasser, Karen Leroy, Marie Wislez, Pierre Laurent-Puig, Isabelle Cremer, Helène Blons, Ronald Herbst
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 573.
https://doi.org/10.1158/1538-7445.AM2019-573
Published: 01 July 2019
View article titled, Abstract 573: Mutations found by targeted next generation sequencing is associated with intra-tumor immune profile and may predict response to anti-PD1 therapy in lung adenocarcinoma
Journal Articles

Abstract 940: Analytical and clinical validation of the Idylla™ ctKRAS and ctNRAS-BRAF liquid biopsy tests identifies mCRC patient groups with high and low ctDNA shedding

Free
Bart Jacobs, Bart Claes, Valentina Pomella, Sabine Tejpar, Jean-Baptiste Bachet, Pierre Laurent-Puig, Geert Maertens, Erwin Sablon
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 940.
https://doi.org/10.1158/1538-7445.AM2018-940
Published: 01 July 2018
View article titled, Abstract 940: Analytical and clinical validation of the Idylla™ ctKRAS and ctNRAS-BRAF liquid biopsy tests identifies mCRC patient groups with high and low ctDNA shedding
Journal Articles

Abstract 5511: Characterization of molecular and functional consequences of somatic NF1 mutations in non-small cell lung cancers

Free
Camille Tlemsani, Nicolas Pecuchet, Aurélia Gruber, Audrey Mansuet-Lupo, Diane Damotte, Marco Alifano, Jennifer Varin, Ingrid Laurendeau, Armelle Luscan, Benoit Rousseau, Beatrice Parfait, Ivan Bieche, Audrey Briand, Benoit Terris, Helene Blons, Karen Leroy, Dominique Vidaud, Michel Vidaud, Pierre Laurent-Puig, Eric Pasmant
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5511.
https://doi.org/10.1158/1538-7445.AM2018-5511
Published: 01 July 2018
View article titled, Abstract 5511: Characterization of molecular and functional consequences of somatic NF1 mutations in non-small cell lung cancers
Journal Articles

Abstract 4603: Clinical application and potential usefulness of targeted next-generation sequencing on resected pancreatic ductal adenocarcinoma

Free
Francesco Puleo, Rémy Nicolle, Yuna Blum, Jérôme Cros, Nabila Elarouci, Denis Franchimont, Jacques Devière, Aurélien de Reyniès, Pierre Laurent-Puig, Jean-Baptiste Bachet, Raphaël Maréchal, Jean-Luc Van Laethem
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4603.
https://doi.org/10.1158/1538-7445.AM2018-4603
Published: 01 July 2018
View article titled, Abstract 4603: Clinical application and potential usefulness of targeted next-generation sequencing on resected pancreatic ductal adenocarcinoma
Journal Articles

Abstract 5694: Multi institutional evaluation of a new NGS assay for mutation detection from cfDNA in lung cancer

Free
Jose L. Costa, Robbert Weren, Anna Maria Rachiglio, Andrea Mafficini, Henriette Kurth, Anne Reiman, Audrey Didelot, Alexander Boag, Claudia Vollbrecht, Kazuto Nishino, Harriet E. Feilotter, Pierre Laurent-Puig, Orla Sheils, Aldo Scarpa, Marjolijn Ligtenberg, Ian A. Cree, Michael Hummel, Jose Carlos Machado, Nicola Normanno
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 5694.
https://doi.org/10.1158/1538-7445.AM2017-5694
Published: 01 July 2017
View article titled, Abstract 5694: Multi institutional evaluation of a new NGS assay for mutation detection from cfDNA in lung cancer
Journal Articles

Abstract 1396: Validation of a MEK/MET-specific NGS panel for early phase trial interrogation

Free
Perry Maxwell, Jurgen Del Favero, Marc-Aurel Fuchs, Josep Tabernero, Tim Maughan, Mark Middleton, Richard Addams, Christian Rolfo, Brian Hennessey, Pierre Laurent-Puig, Alberto Bardelli, Thierry Andre, Vlad Popovici, Patrick Johnstone, Richard Wilson, Mark Lawler, Sandra Van Schaeybroeck, Manuel Salto Tellez
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1396.
https://doi.org/10.1158/1538-7445.AM2016-1396
Published: 15 July 2016
View article titled, Abstract 1396: Validation of a MEK/MET-specific NGS panel for early phase trial interrogation
Journal Articles

Abstract 4924: Retrospective evaluation of a system model of the BCL2 family of proteins as a predictive and prognostic biomarker for the clinical outcome of stage II-IV colorectal cancer patients

Free
Andreas U. Lindner, Manuela Salvucci, Mattia Cremona, Naser Monsefi, Sarah Curry, Clare Morgan, Alexa Resler, Robert O’Byrne, Orna Bacon, Michael Stuehler, Lorna Flanagan, Richard Wilson, Patrick G. Johnston, Manuel Salto-Tellez, Sophie Camilleri-Broët, Deborah A. McNamara, Bryan T. Hennessy, Elaine W. Kay, Pierre Laurent-Puig, Sandra Van Schaeybroeck, Jochen H.M. Prehn
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4924.
https://doi.org/10.1158/1538-7445.AM2016-4924
Published: 15 July 2016
View article titled, Abstract 4924: Retrospective evaluation of a system model of the BCL2 family of proteins as a predictive and prognostic biomarker for the clinical outcome of stage II-IV colorectal cancer patients
Journal Articles

Abstract 508: Prognostic value of circulating tumor DNA in advanced colorectal cancer patients: quantification of hypermethylated or mutant sequences using picoliter-droplet digital PCR

Free
Fanny Garlan, Pierre Laurent-Puig, Nathalie Siauve, Audrey Didelot, Geraldine Perkins, Hélène Blons, Julien Taieb, Valerie Taly, Aziz Zaanan
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 508.
https://doi.org/10.1158/1538-7445.AM2016-508
Published: 15 July 2016
View article titled, Abstract 508: Prognostic value of circulating tumor DNA in advanced colorectal cancer patients: quantification of hypermethylated or mutant sequences using picoliter-droplet digital PCR
Journal Articles

Abstract 4891: Comprehensive genetic profiling of chromosomal translocations in lung cancer tumors: development and validation of a next-generation sequencing panel in an international multicenter study

Free
Pierre Laurent - Puig, Jose Louis Costa, Orla Sheils, Bastiaan Tops, Andrea Mafficini, Delphine Le Corre, Henriette Kurth, Anna Maria Rachiglio, Helene Blons, Eliana Amato, Christoph Noppen, Renato Franco, Anne Reiman, Roy Bastien, Noah Welker, Jose Carlos Machado, Ian Cree, Harriet Feilotter, Marjolijn Ligtenberg, Aldo Scarpa, Nicola Normanno, Kazuto Nishio, Cecily Vaughn
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 4891.
https://doi.org/10.1158/1538-7445.AM2015-4891
Published: 01 August 2015
View article titled, Abstract 4891: Comprehensive genetic profiling of chromosomal translocations in lung cancer tumors: development and validation of a next-generation sequencing panel in an international multicenter study
Journal Articles

Abstract 5235: Circulating tumor DNA as a prognostic marker in colorectal cancer: Preliminary results of a prospective trial

Free
Pierre Laurent-Puig, Olivier Bouché, Ralph Niarra, Pascaline Aucouturier, Leonor Benhaim, Bruno Landi, Anne Berger, Thierry Lecomte, Corinne Normand, Delphine Le Corre, Audrey Didelot, Karine Mallet, Karla Perez Toralla, Thevy Hor, Zakaria El Harrak, Gilles Chatellier, Brian Hutchison, Darren Link, Valerie Taly
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 5235.
https://doi.org/10.1158/1538-7445.AM2015-5235
Published: 01 August 2015
View article titled, Abstract 5235: Circulating tumor DNA as a prognostic marker in colorectal cancer: Preliminary results of a prospective trial
Journal Articles

Abstract 580: hENT1 testing in pancreatic ductal adenocarcinoma: Are we ready yet? A comparative analysis of the murine and the rabbit antibodies

Free
Jerome Cros, Raphael Marechal, Jean Baptiste Bachet, Pierre Laurent-Puig, Jean Francois Flejou, Pieter Demetter, Magali Svrcek
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 580.
https://doi.org/10.1158/1538-7445.AM2015-580
Published: 01 August 2015
View article titled, Abstract 580: hENT1 testing in pancreatic ductal adenocarcinoma: Are we ready yet? A comparative analysis of the murine and the rabbit antibodies
Journal Articles

Abstract 603: Consensus molecular subtyping through a community of experts advances unsupervised gene expression-based disease classification and facilitates clinical translation

Free
Justin Guinney, Rodrigo Dienstmann, Xin Wang, Aurelien de Reynies, Andreas Schlicker, Charlotte Soneson, Laetitia Marisa, Paul Roepman, Gift Nyamundanda, Paolo Angelino, Brian Bot, Jeffrey S. Morris, Iris Simon, Sarah Gerster, Evelyn Fessler, Felipe de Sousa e Melo, Edoardo Missiaglia, Hena Ramay, David Barras, Krisztian Homicsko, Dipen Maru, Ganiraju Manyam, Bradley Broom, Valerie Boige, Ted Laderas, Ramon Salazar, Joe W. Gray, Josep Tabernero, Rene Bernards, Stephen Friend, Pierre Laurent-Puig, Jan P. Medema, Anguraj Sadanandam, Lodewyk Wessels, Mauro Delorenzi, Scott Kopetz, Louis Vermeulen, Sabine Tejpar
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 603.
https://doi.org/10.1158/1538-7445.AM2015-603
Published: 01 August 2015
View article titled, Abstract 603: Consensus molecular subtyping through a community of experts advances unsupervised gene expression-based disease classification and facilitates clinical translation
Journal Articles

Abstract 3575: The OncoNetwork Consortium: A global collaborative research study on the development and verification of an Ion AmpliSeq RNA gene lung fusion panel

Free
Susan M. Magdaleno, Angie Cheng, Rosella Petraroli, Orla Sheils, Bastiaan Tops, Delphine L. Corre, Henriette Kurth, Helene Blons, Eliana Amato, Andrea Mafficini, Anna Maria Rachiglio, Anne Reimann, Christoph Noppen, Chrysanthi Ainali, Jin Katayama, Renato Franco, Harriet Feilotter, Jeoffrey Schageman, Ian Cree, Andrew Felton, Jose Luis Costa, Alain Rico, Aldo Scarpa, Jose Carlos Machado, Kazuto Nishio, Nicola Normanno, Marjolijn Ligtenberg, Cecily P. Vaughn, Ludovic Lacroix, Pierre Laurent-Puig
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3575.
https://doi.org/10.1158/1538-7445.AM2014-3575
Published: 01 October 2014
View article titled, Abstract 3575: The OncoNetwork Consortium: A global collaborative research study on the development and verification of an Ion AmpliSeq RNA gene lung fusion panel
Journal Articles

Abstract 2820: Clinical significance of low frequency KRAS and BRAF subclones for advanced colon cancer management

Free
Valerie Taly, Pierre Laurent-puig, Deniz Pekin, Corinne Normand, Steve K. Kotsopoulos, Philippe Nizard, Jeff Olson, Preethi Srinivasan, Delphine L. Corre, Xinyu Li, Qun Zhong, Darren R. Link, Olivier Bouché, Jean-François Emile, Bruno Landi, Valérie Boige, Brian J. Hutchison
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2820.
https://doi.org/10.1158/1538-7445.AM2014-2820
Published: 01 October 2014
View article titled, Abstract 2820: Clinical significance of low frequency KRAS and BRAF subclones for advanced colon cancer management
Journal Articles

Abstract 36: The OncoNetwork Consortium: A European Collaborative Research study on the development of an Ion AmpliSeq gene panel targeting hot spots in colon and lung cancers.

Free
Nicola Normanno, Rosella Petraroli, Alain Rico, Henriette Kurth, Bastiaan Tops, Eliana Amato, Andrea Mafficini, Delphine Le Corre, Anna Maria Rachiglio, Anne Reiman, Orla Sheils, Christoph Noppen, Nora Rieber, Jonathan Mangion, Chrysanthi Ainali, Ludovic Lacroix, Ian Cree, Marjolijn Ligtenberg, Andy Felton, Aldo Scarpa, Pierre Laurent Puig
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 36.
https://doi.org/10.1158/1538-7445.AM2013-36
Published: 15 April 2013
View article titled, Abstract 36: The OncoNetwork Consortium: A European Collaborative Research study on the development of an Ion AmpliSeq gene panel targeting hot spots in colon and lung cancers.