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Abstract A005 TP53 variant clusters stratify the Li-Fraumeni spectrum and reveal an osteosarcoma-prone subgroup

Nicholas W. Fischer, Brianne Laverty, Noa Alon, Emilie Montellier, Pierre Hainaut, Kara N. Maxwell, Christian P. Kratz, David Malkin

Cancer Res (2024) 84 (17_Supplement): A005.

https://doi.org/10.1158/1538-7445.PEDIATRIC24-A005

Published: 05 September 2024

View articletitled, Abstract A005 TP53 variant clusters stratify the Li-Fraumeni spectrum and reveal an osteosarcoma-prone subgroup

Journal Articles

Abstract 3564: Survival-based grouping of genetic variants: A novel statistical framework with an application to TP53 mutations

Xiaoqian Liu, Haoming Shi, Emilie Montellier, Pierre Hainaut, Wenyi Wang

Cancer Res (2024) 84 (6_Supplement): 3564.

https://doi.org/10.1158/1538-7445.AM2024-3564

Published: 22 March 2024

View articletitled, Abstract 3564: Survival-based grouping of genetic variants: A novel statistical framework with an application to TP53 mutations

Journal Articles

Abstract 4282: Germline TP53 p.R337H mutations and Li-Fraumeni syndrome: A new variant form of the disease

Claire Freycon, Kelvin César De Andrade, Amina Yacouba, Maria Nirvana Formiga, Camila Bittar, Karina Miranda Santiago, Sharon Savage, Patricia Ashton-Prolla, Pierre Hainaut, Maria Isabel Achatz

Cancer Res (2017) 77 (13_Supplement): 4282.

https://doi.org/10.1158/1538-7445.AM2017-4282

Published: 01 July 2017

View articletitled, Abstract 4282: Germline TP53 p.R337H mutations and Li-Fraumeni syndrome: A new variant form of the disease

Journal Articles

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Cancer Res (2017) 77 (6): 1250–1260.

https://doi.org/10.1158/0008-5472.CAN-16-2179

Published: 14 March 2017

View articletitled, Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Includes: Supplementary data

Journal Articles

Abstract A44: Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer

Pawel K. Mazur, Nicolas Reynoird, Timo Stellfeld, Natasha M. Flores, Shane M. Lofgren, Scott M. Carlson, Elisabeth Brambilla, Pierre Hainaut, Ewa B. Kaznowska, Cheryl H. Arrowsmith, Purvesh Khatri, Carlo Stresemann, Or Gozani, Julien Sage

Cancer Res (2016) 76 (24_Supplement): A44.

https://doi.org/10.1158/1538-7445.PANCA16-A44

Published: 14 December 2016

View articletitled, Abstract A44: Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer

Journal Articles

Abstract 4468: Targeted deep sequencing of plasma circulating cell-free DNA shows VIM and FBLN1 methylation as potential biomarkers for hepatocellular carcinoma

Reetta Holmila, Athena Sklias, David C. Muller, Davide Degli Esposti, Paule Guilloreau, James Mckay, Suleeporn Sangrajrang, Petcharin Srivatanakul, Pierre Hainaut, Philippe Merle, Andre Nogueira da Costa, Zdenko Herceg

Cancer Res (2016) 76 (14_Supplement): 4468.

https://doi.org/10.1158/1538-7445.AM2016-4468

Published: 15 July 2016

View articletitled, Abstract 4468: Targeted deep sequencing of plasma circulating cell-free DNA shows VIM and FBLN1 methylation as potential biomarkers for hepatocellular carcinoma

Journal Articles

Abstract 2000: Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples.

Florence Le Calvez-Kelm, Elodie Caboux, Maria Paciencia, Geoffroy Durand, Nivonirina Robinot, Magdalena Wozniak, Francoise Galateau-Salle, Graham Byrnes, Pierre Hainaut

Cancer Res (2013) 73 (8_Supplement): 2000.

https://doi.org/10.1158/1538-7445.AM2013-2000

Published: 15 April 2013

View articletitled, Abstract 2000: Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples.

Journal Articles

Abstract 3771: Establishment of primary cultures of cancer stem cells from patients with Li-Fraumeni Syndrome, carrier of TP53 p.R337H Brazilian founder mutation.

Lisley I. Mambelli, Irina Kerkis, Pierre Hainaut, Maria Isabel W. Achatz

Cancer Res (2013) 73 (8_Supplement): 3771.

https://doi.org/10.1158/1538-7445.AM2013-3771

Published: 15 April 2013

View articletitled, Abstract 3771: Establishment of primary cultures of cancer stem cells from patients with Li-Fraumeni Syndrome, carrier of TP53 p.R337H Brazilian founder mutation.

Journal Articles

Abstract 5349: Cancer stem cells isolation and characterization from breast tumor of a germline carrier of TP53 p.R337H (Brazilian founder) mutation

Lisley I. Mambelli, Irina Kerkis, Pierre Hainaut, Maria Isabel W. Achatz

Cancer Res (2012) 72 (8_Supplement): 5349.

https://doi.org/10.1158/1538-7445.AM2012-5349

Published: 15 April 2012

View articletitled, Abstract 5349: Cancer stem cells isolation and characterization from breast tumor of a germline carrier of TP53 p.R337H (Brazilian founder) mutation

Journal Articles

Abstract 5598: Germline TP53 mutation in very early onset breast cancer patients without BRCA1 and BRCA2 mutation in Brazilian population

Marina C. Cannavan, Bianca CG Lisboa, Maria M. Brentani, Edenir I. Palmero, Ghyslaine Martel-Planche, Pierre Hainaut, Dirce M. Carraro, Maria Isabel W. Achatz

Cancer Res (2011) 71 (8_Supplement): 5598.

https://doi.org/10.1158/1538-7445.AM2011-5598

Published: 15 April 2011

View articletitled, Abstract 5598: Germline TP53 mutation in very early onset breast cancer patients without BRCA1 and BRCA2 mutation in Brazilian population

Journal Articles

Abstract 1836: Distinct tumor spectrum and age of onset in a Brazilian cohort of p.R337H TP53 mutation carriers

Hadrien Hainaut, Sonia Nogueira, Amanda Nobrega, Pierre Hainaut, Maria I. Achatz

Cancer Res (2011) 71 (8_Supplement): 1836.

https://doi.org/10.1158/1538-7445.AM2011-1836

Published: 15 April 2011

View articletitled, Abstract 1836: Distinct tumor spectrum and age of onset in a Brazilian cohort of p.R337H TP53 mutation carriers

Journal Articles

Abstract 5538: Sarcomas in TP53 germline mutation carriers

Simona Ognjanovic, Magali Olivier, Tracy L. Bergemann, Pierre Hainaut

Cancer Res (2011) 71 (8_Supplement): 5538.

https://doi.org/10.1158/1538-7445.AM2011-5538

Published: 15 April 2011

View articletitled, Abstract 5538: Sarcomas in TP53 germline mutation carriers

Journal Articles

MicroRNA Expression and Clinical Outcomes in Patients Treated with Adjuvant Chemotherapy after Complete Resection of Non–Small Cell Lung Carcinoma

Johannes Voortman, Akiteru Goto, Jean Mendiboure, Jane J. Sohn, Aaron J. Schetter, Motonobu Saito, Ariane Dunant, Trung C. Pham, Iacopo Petrini, Alan Lee, Mohammed A. Khan, Pierre Hainaut, Jean-Pierre Pignon, Elisabeth Brambilla, Helmut H. Popper, Martin Filipits, Curtis C. Harris, Giuseppe Giaccone

Cancer Res (2010) 70 (21): 8288–8298.

https://doi.org/10.1158/0008-5472.CAN-10-1348

Published: 31 October 2010

View articletitled, MicroRNA Expression and Clinical Outcomes in Patients Treated with Adjuvant Chemotherapy after Complete Resection of Non–Small Cell Lung Carcinoma

Includes: Supplementary data

Journal Articles

Abstract 1120: Low prevalence of TP53 mutations in pediatric rhabdomyosarcoma

Simona Ognjanovic, Ghyslaine Martel-Planche, Magali Olivier, Pierre Hainaut

Cancer Res (2010) 70 (8_Supplement): 1120.

https://doi.org/10.1158/1538-7445.AM10-1120

Published: 15 April 2010

View articletitled, Abstract 1120: Low prevalence of TP53 mutations in pediatric rhabdomyosarcoma

Journal Articles

Abstract 2995: MicroRNA expression and outcome of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: International Adjuvant Lung Cancer Trial Biologic Program (IALT-Bio)

Johannes Voortman, Akiteru Goto, Jean Mendiboure, Jane J. Sohn, Aaron J. Schetter, Ariane Dunant, Mohamed Khan, Trung C. Pham, Iacopo Petrini, Alan Lee, Pierre Hainaut, Jean-Pierre Pignon, Elisabeth Brambilla, Helmut H. Popper, Martin Filipits, Curtis C. Harris, Giuseppe Giaccone

Cancer Res (2010) 70 (8_Supplement): 2995.

https://doi.org/10.1158/1538-7445.AM10-2995

Published: 15 April 2010

View articletitled, Abstract 2995: MicroRNA expression and outcome of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: International Adjuvant Lung Cancer Trial Biologic Program (IALT-Bio)

Journal Articles

Aberrant DNA Methylation Links Cancer Susceptibility Locus 15q25.1 to Apoptotic Regulation and Lung Cancer

Anupam Paliwal, Thomas Vaissière, Annette Krais, Cyrille Cuenin, Marie-Pierre Cros, David Zaridze, Anush Moukeria, Paolo Boffetta, Pierre Hainaut, Paul Brennan, Zdenko Herceg

Cancer Res (2010) 70 (7): 2779–2788.

https://doi.org/10.1158/0008-5472.CAN-09-4550

Published: 31 March 2010

View articletitled, Aberrant DNA Methylation Links Cancer Susceptibility Locus 15q25.1 to Apoptotic Regulation and Lung Cancer

Includes: Supplementary data

Journal Articles

Abstract #3565: Biomarkers predict p53 gene therapy efficacy in recurrent squamous cell carcinoma of the head and neck (SCCHN)

Cancer Res (2009) 69 (9_Supplement): 3565.

Published: 01 May 2009

View articletitled, Abstract #3565: Biomarkers predict p53 gene therapy efficacy in recurrent squamous cell carcinoma of the head and neck (SCCHN)

Journal Articles

Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors

Thomas Vaissière, Rayjean J. Hung, David Zaridze, Anush Moukeria, Cyrille Cuenin, Virginie Fasolo, Gilles Ferro, Anupam Paliwal, Pierre Hainaut, Paul Brennan, Jörg Tost, Paolo Boffetta, Zdenko Herceg

Cancer Res (2009) 69 (1): 243–252.

https://doi.org/10.1158/0008-5472.CAN-08-2489

Published: 31 December 2008

View articletitled, Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors

Includes: Supplementary data

Journal Articles

Mistaken Identity of Widely Used Esophageal Adenocarcinoma Cell Line TE-7

Jurjen J. Boonstra, Albertina W. van der Velden, Erwin C.W. Beerens, Ronald van Marion, Yuiko Morita-Fujimura, Yasuhisa Matsui, Tetsuro Nishihira, Chris Tselepis, Pierre Hainaut, Anson W. Lowe, Berna H. Beverloo, Herman van Dekken, Hugo W. Tilanus, Winand N.M. Dinjens

Cancer Res (2007) 67 (17): 7996–8001.

https://doi.org/10.1158/0008-5472.CAN-07-2064

Published: 05 September 2007

View articletitled, Mistaken Identity of Widely Used Esophageal Adenocarcinoma Cell Line TE-7

Journal Articles

Patterns of EGFR, HER2, TP53, and KRAS Mutations of p14^arf Expression in Non–Small Cell Lung Cancers in Relation to Smoking History

Mounia Mounawar, Anush Mukeria, Florence Le Calvez, Rayjean J. Hung, Helene Renard, Alexis Cortot, Claire Bollart, David Zaridze, Paul Brennan, Paolo Boffetta, Elisabeth Brambilla, Pierre Hainaut

Cancer Res (2007) 67 (12): 5667–5672.

https://doi.org/10.1158/0008-5472.CAN-06-4229

Published: 15 June 2007

View articletitled, Patterns of EGFR, HER2, TP53, and KRAS Mutations of p14arf Expression in Non–Small Cell Lung Cancers in Relation to Smoking History

Includes: Supplementary data

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Abstract A005 TP53 variant clusters stratify the Li-Fraumeni spectrum and reveal an osteosarcoma-prone subgroup

Abstract 3564: Survival-based grouping of genetic variants: A novel statistical framework with an application to TP53 mutations

Abstract 4282: Germline TP53 p.R337H mutations and Li-Fraumeni syndrome: A new variant form of the disease

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Abstract A44: Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer

Abstract 4468: Targeted deep sequencing of plasma circulating cell-free DNA shows VIM and FBLN1 methylation as potential biomarkers for hepatocellular carcinoma

Abstract 2000: Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples.

Abstract 3771: Establishment of primary cultures of cancer stem cells from patients with Li-Fraumeni Syndrome, carrier of TP53 p.R337H Brazilian founder mutation.

Abstract 5349: Cancer stem cells isolation and characterization from breast tumor of a germline carrier of TP53 p.R337H (Brazilian founder) mutation

Abstract 5598: Germline TP53 mutation in very early onset breast cancer patients without BRCA1 and BRCA2 mutation in Brazilian population

Abstract 1836: Distinct tumor spectrum and age of onset in a Brazilian cohort of p.R337H TP53 mutation carriers

Abstract 5538: Sarcomas in TP53 germline mutation carriers

MicroRNA Expression and Clinical Outcomes in Patients Treated with Adjuvant Chemotherapy after Complete Resection of Non–Small Cell Lung Carcinoma

Abstract 1120: Low prevalence of TP53 mutations in pediatric rhabdomyosarcoma

Abstract 2995: MicroRNA expression and outcome of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: International Adjuvant Lung Cancer Trial Biologic Program (IALT-Bio)

Aberrant DNA Methylation Links Cancer Susceptibility Locus 15q25.1 to Apoptotic Regulation and Lung Cancer

Abstract #3565: Biomarkers predict p53 gene therapy efficacy in recurrent squamous cell carcinoma of the head and neck (SCCHN)

Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors

Mistaken Identity of Widely Used Esophageal Adenocarcinoma Cell Line TE-7

Patterns of EGFR, HER2, TP53, and KRAS Mutations of p14^arf Expression in Non–Small Cell Lung Cancers in Relation to Smoking History

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