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Pierre Hainaut
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Journal Articles

Abstract 4282: Germline TP53 p.R337H mutations and Li-Fraumeni syndrome: A new variant form of the disease

Claire Freycon, Kelvin César De Andrade, Amina Yacouba, Maria Nirvana Formiga, Camila Bittar, Karina Miranda Santiago, Sharon Savage, Patricia Ashton-Prolla, Pierre Hainaut, Maria Isabel Achatz
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 4282.
https://doi.org/10.1158/1538-7445.AM2017-4282
Published: 01 July 2017
View article titled, Abstract 4282: Germline <em>TP53</em> p.R337H mutations and Li-Fraumeni syndrome: A new variant form of the disease
Journal Articles

Recommended Guidelines for Validation, Quality Control, and Reporting of TP53 Variants in Clinical Practice

Bernard Leroy, Mandy L. Ballinger, Fanny Baran-Marszak, Gareth L. Bond, Antony Braithwaite, Nicole Concin, Lawrence A. Donehower, Wafik S. El-Deiry, Pierre Fenaux, Gianluca Gaidano, Anita Langerød, Eva Hellstrom-Lindberg, Richard Iggo, Jacqueline Lehmann-Che, Phuong L. Mai, David Malkin, Ute M. Moll, Jeffrey N. Myers, Kim E. Nichols, Sarka Pospisilova, Patricia Ashton-Prolla, Davide Rossi, Sharon A. Savage, Louise C. Strong, Patricia N. Tonin, Robert Zeillinger, Thorsten Zenz, Joseph F. Fraumeni, Jr, Peter E.M. Taschner, Pierre Hainaut, Thierry Soussi
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (6): 1250–1260.
https://doi.org/10.1158/0008-5472.CAN-16-2179
Published: 14 March 2017
View article titled, Recommended Guidelines for Validation, Quality Control, and Reporting of <em>TP53</em> Variants in Clinical Practice
Open the PDF for Recommended Guidelines for Validation, Quality Control, and Reporting of <em>TP53</em> Variants in Clinical Practice in another window
Includes: Supplementary data
Journal Articles

Abstract A44: Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer

Pawel K. Mazur, Nicolas Reynoird, Timo Stellfeld, Natasha M. Flores, Shane M. Lofgren, Scott M. Carlson, Elisabeth Brambilla, Pierre Hainaut, Ewa B. Kaznowska, Cheryl H. Arrowsmith, Purvesh Khatri, Carlo Stresemann, Or Gozani, Julien Sage
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): A44.
https://doi.org/10.1158/1538-7445.PANCA16-A44
Published: 14 December 2016
View article titled, Abstract A44: Coordination of stress signals by the lysine methyltransferase SMYD2 promotes pancreatic cancer
Journal Articles

Abstract 4468: Targeted deep sequencing of plasma circulating cell-free DNA shows VIM and FBLN1 methylation as potential biomarkers for hepatocellular carcinoma

Reetta Holmila, Athena Sklias, David C. Muller, Davide Degli Esposti, Paule Guilloreau, James Mckay, Suleeporn Sangrajrang, Petcharin Srivatanakul, Pierre Hainaut, Philippe Merle, Andre Nogueira da Costa, Zdenko Herceg
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4468.
https://doi.org/10.1158/1538-7445.AM2016-4468
Published: 15 July 2016
View article titled, Abstract 4468: Targeted deep sequencing of plasma circulating cell-free DNA shows VIM and FBLN1 methylation as potential biomarkers for hepatocellular carcinoma
Journal Articles

Abstract 3771: Establishment of primary cultures of cancer stem cells from patients with Li-Fraumeni Syndrome, carrier of TP53 p.R337H Brazilian founder mutation.

Lisley I. Mambelli, Irina Kerkis, Pierre Hainaut, Maria Isabel W. Achatz
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3771.
https://doi.org/10.1158/1538-7445.AM2013-3771
Published: 15 April 2013
View article titled, Abstract 3771: Establishment of primary cultures of cancer stem cells from patients with Li-Fraumeni Syndrome, carrier of TP53 p.R337H Brazilian founder mutation.
Journal Articles

Abstract 2000: Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples.

Florence Le Calvez-Kelm, Elodie Caboux, Maria Paciencia, Geoffroy Durand, Nivonirina Robinot, Magdalena Wozniak, Francoise Galateau-Salle, Graham Byrnes, Pierre Hainaut
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2000.
https://doi.org/10.1158/1538-7445.AM2013-2000
Published: 15 April 2013
View article titled, Abstract 2000: Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples.
Journal Articles

Abstract 5349: Cancer stem cells isolation and characterization from breast tumor of a germline carrier of TP53 p.R337H (Brazilian founder) mutation

Lisley I. Mambelli, Irina Kerkis, Pierre Hainaut, Maria Isabel W. Achatz
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5349.
https://doi.org/10.1158/1538-7445.AM2012-5349
Published: 15 April 2012
View article titled, Abstract 5349: Cancer stem cells isolation and characterization from breast tumor of a germline carrier of TP53 p.R337H (Brazilian founder) mutation
Journal Articles

Abstract 1836: Distinct tumor spectrum and age of onset in a Brazilian cohort of p.R337H TP53 mutation carriers

Hadrien Hainaut, Sonia Nogueira, Amanda Nobrega, Pierre Hainaut, Maria I. Achatz
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 1836.
https://doi.org/10.1158/1538-7445.AM2011-1836
Published: 15 April 2011
View article titled, Abstract 1836: Distinct tumor spectrum and age of onset in a Brazilian cohort of p.R337H <em>TP53</em> mutation carriers
Journal Articles

Abstract 5538: Sarcomas in TP53 germline mutation carriers

Simona Ognjanovic, Magali Olivier, Tracy L. Bergemann, Pierre Hainaut
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5538.
https://doi.org/10.1158/1538-7445.AM2011-5538
Published: 15 April 2011
View article titled, Abstract 5538: Sarcomas in TP53 germline mutation carriers
Journal Articles

Abstract 5598: Germline TP53 mutation in very early onset breast cancer patients without BRCA1 and BRCA2 mutation in Brazilian population

Marina C. Cannavan, Bianca CG Lisboa, Maria M. Brentani, Edenir I. Palmero, Ghyslaine Martel-Planche, Pierre Hainaut, Dirce M. Carraro, Maria Isabel W. Achatz
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 5598.
https://doi.org/10.1158/1538-7445.AM2011-5598
Published: 15 April 2011
View article titled, Abstract 5598: Germline TP53 mutation in very early onset breast cancer patients without BRCA1 and BRCA2 mutation in Brazilian population
Journal Articles

MicroRNA Expression and Clinical Outcomes in Patients Treated with Adjuvant Chemotherapy after Complete Resection of Non–Small Cell Lung Carcinoma

Johannes Voortman, Akiteru Goto, Jean Mendiboure, Jane J. Sohn, Aaron J. Schetter, Motonobu Saito, Ariane Dunant, Trung C. Pham, Iacopo Petrini, Alan Lee, Mohammed A. Khan, Pierre Hainaut, Jean-Pierre Pignon, Elisabeth Brambilla, Helmut H. Popper, Martin Filipits, Curtis C. Harris, Giuseppe Giaccone
Journal: Cancer Research
Cancer Res (2010) 70 (21): 8288–8298.
https://doi.org/10.1158/0008-5472.CAN-10-1348
Published: 31 October 2010
View article titled, MicroRNA Expression and Clinical Outcomes in Patients Treated with Adjuvant Chemotherapy after Complete Resection of Non–Small Cell Lung Carcinoma
Open the PDF for MicroRNA Expression and Clinical Outcomes in Patients Treated with Adjuvant Chemotherapy after Complete Resection of Non–Small Cell Lung Carcinoma in another window
Includes: Supplementary data
Journal Articles

Abstract 1120: Low prevalence of TP53 mutations in pediatric rhabdomyosarcoma

Simona Ognjanovic, Ghyslaine Martel-Planche, Magali Olivier, Pierre Hainaut
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1120.
https://doi.org/10.1158/1538-7445.AM10-1120
Published: 15 April 2010
View article titled, Abstract 1120: Low prevalence of <em>TP53</em> mutations in pediatric rhabdomyosarcoma
Journal Articles

Abstract 2995: MicroRNA expression and outcome of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: International Adjuvant Lung Cancer Trial Biologic Program (IALT-Bio)

Johannes Voortman, Akiteru Goto, Jean Mendiboure, Jane J. Sohn, Aaron J. Schetter, Ariane Dunant, Mohamed Khan, Trung C. Pham, Iacopo Petrini, Alan Lee, Pierre Hainaut, Jean-Pierre Pignon, Elisabeth Brambilla, Helmut H. Popper, Martin Filipits, Curtis C. Harris, Giuseppe Giaccone
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 2995.
https://doi.org/10.1158/1538-7445.AM10-2995
Published: 15 April 2010
View article titled, Abstract 2995: MicroRNA expression and outcome of adjuvant chemotherapy in patients with completely resected non-small cell lung cancer: International Adjuvant Lung Cancer Trial Biologic Program (IALT-Bio)
Journal Articles

Aberrant DNA Methylation Links Cancer Susceptibility Locus 15q25.1 to Apoptotic Regulation and Lung Cancer

Anupam Paliwal, Thomas Vaissière, Annette Krais, Cyrille Cuenin, Marie-Pierre Cros, David Zaridze, Anush Moukeria, Paolo Boffetta, Pierre Hainaut, Paul Brennan, Zdenko Herceg
Journal: Cancer Research
Cancer Res (2010) 70 (7): 2779–2788.
https://doi.org/10.1158/0008-5472.CAN-09-4550
Published: 31 March 2010
View article titled, Aberrant DNA Methylation Links Cancer Susceptibility Locus 15q25.1 to Apoptotic Regulation and Lung Cancer
Open the PDF for Aberrant DNA Methylation Links Cancer Susceptibility Locus 15q25.1 to Apoptotic Regulation and Lung Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract #3565: Biomarkers predict p53 gene therapy efficacy in recurrent squamous cell carcinoma of the head and neck (SCCHN)

Robert Sobol, John Nemunaitis, Gary Clayman, Jack Roth, Magali Olivier, Pierre Hainaut, Sanjiv Agarwala, William Hrushesky, James Wells, Charles Moore, John Hamm, George Yoo, Jose Baselga, Barbara Murphy, Kerstin Menander, Sunil Chada, Laura Licato, Robert Gibbons, W. Jarrard Goodwin, y Group ADVEXIN p53 Gene Therapy Head and Neck Cancer Stud
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 3565.
Published: 01 May 2009
View article titled, Abstract #3565: Biomarkers predict <em>p53</em> gene therapy efficacy in recurrent squamous cell carcinoma of the head and neck (SCCHN)
Journal Articles

Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors

Thomas Vaissière, Rayjean J. Hung, David Zaridze, Anush Moukeria, Cyrille Cuenin, Virginie Fasolo, Gilles Ferro, Anupam Paliwal, Pierre Hainaut, Paul Brennan, Jörg Tost, Paolo Boffetta, Zdenko Herceg
Journal: Cancer Research
Cancer Res (2009) 69 (1): 243–252.
https://doi.org/10.1158/0008-5472.CAN-08-2489
Published: 31 December 2008
View article titled, Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors
Open the PDF for Quantitative Analysis of DNA Methylation Profiles in Lung Cancer Identifies Aberrant DNA Methylation of Specific Genes and Its Association with Gender and Cancer Risk Factors in another window
Includes: Supplementary data
Journal Articles

Mistaken Identity of Widely Used Esophageal Adenocarcinoma Cell Line TE-7

Jurjen J. Boonstra, Albertina W. van der Velden, Erwin C.W. Beerens, Ronald van Marion, Yuiko Morita-Fujimura, Yasuhisa Matsui, Tetsuro Nishihira, Chris Tselepis, Pierre Hainaut, Anson W. Lowe, Berna H. Beverloo, Herman van Dekken, Hugo W. Tilanus, Winand N.M. Dinjens
Journal: Cancer Research
Cancer Res (2007) 67 (17): 7996–8001.
https://doi.org/10.1158/0008-5472.CAN-07-2064
Published: 05 September 2007
View article titled, Mistaken Identity of Widely Used Esophageal Adenocarcinoma Cell Line TE-7
Open the PDF for Mistaken Identity of Widely Used Esophageal Adenocarcinoma Cell Line TE-7 in another window
Journal Articles

Patterns of EGFR, HER2, TP53, and KRAS Mutations of p14arf Expression in Non–Small Cell Lung Cancers in Relation to Smoking History

Mounia Mounawar, Anush Mukeria, Florence Le Calvez, Rayjean J. Hung, Helene Renard, Alexis Cortot, Claire Bollart, David Zaridze, Paul Brennan, Paolo Boffetta, Elisabeth Brambilla, Pierre Hainaut
Journal: Cancer Research
Cancer Res (2007) 67 (12): 5667–5672.
https://doi.org/10.1158/0008-5472.CAN-06-4229
Published: 15 June 2007
View article titled, Patterns of <em>EGFR, HER2, TP53</em>, and <em>KRAS</em> Mutations of p14<sup>arf</sup> Expression in Non–Small Cell Lung Cancers in Relation to Smoking History
Open the PDF for Patterns of <em>EGFR, HER2, TP53</em>, and <em>KRAS</em> Mutations of p14<sup>arf</sup> Expression in Non–Small Cell Lung Cancers in Relation to Smoking History in another window
Includes: Supplementary data
Journal Articles

TP53 mutations and HPV infections in tumors of the upper aerodigestive tract from Latin America

Katarzyna Szymanska, Jose Levi, Alexander Daudt, Victor Wunsch-Filho, Jose Eluf-Neto, Maria Curado, Sergio Koifman, Ana Menezes, Elena Matos, Leticia Fernandez, Paolo Boffetta, Massimo Tommasino, Tarik Gheit, Pierre Hainaut, Paul Brennan
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 1744.
Published: 01 May 2007
View article titled, <em>TP53</em> mutations and HPV infections in tumors of the upper aerodigestive tract from Latin America
Journal Articles

Patterns of EGFR, HER2, TP53, KRAS mutations and of p14arf expression in non-small cell lung cancers in relation with smoking history

Mounia Mounawar, Anush Mukeria, David Zaridze, Florence Le Calvez, Rayjean Hung, Alexis Cortot, Helene Renard, Paul Brennan, Paolo Boffetta, Elisabeth Brambilla, Pierre Hainaut
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 5242.
Published: 01 May 2007
View article titled, Patterns of EGFR, HER2, TP53, KRAS mutations and of p14arf expression in non-small cell lung cancers in relation with smoking history