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Pierluigi Porcu
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Journal Articles

Abstract LB422: Specific activation of the Epstein-Barr Virus BGLF4 locus via lowered DNA methylation in EBV-associated CNS lymphoproliferative disease

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Christoph Weigel, Haley L. Klimaszewski, Selamawit Addissie, Sarah Schlotter, Fode Tounkara, James P. Dugan, Bradley M. Haverkos, Lynda Villagomez, Mark Lustberg, Pierluigi Porcu, Timothy Voorhees, Michael A. Caligiuri, Ginny Bumgardner, Christopher C. Oakes, Robert Baiocchi
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): LB422.
https://doi.org/10.1158/1538-7445.AM2024-LB422
Published: 05 April 2024
View articletitled, Abstract LB422: Specific activation of the Epstein-Barr Virus BGLF4 locus via lowered DNA methylation in EBV-associated CNS lymphoproliferative disease
Journal Articles

Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression

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Patrizia Porazzi, Svetlana Petruk, Luca Pagliaroli, Marco De Dominici, David Deming, II, Matthew V. Puccetti, Saul Kushinsky, Gaurav Kumar, Valentina Minieri, Elisa Barbieri, Sandra Deliard, Alexis Grande, Marco Trizzino, Alessandro Gardini, Eli Canaani, Neil Palmisiano, Pierluigi Porcu, Adam Ertel, Paolo Fortina, Christine M. Eischen, Alexander Mazo, Bruno Calabretta
Journal: Cancer Research
Cancer Res (2022) 82 (3): 458–471.
https://doi.org/10.1158/0008-5472.CAN-21-1297
Published: 02 February 2022
View articletitled, Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression
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Includes: Supplementary data
Journal Articles

Abstract LB-102: Extranodal natural killer/T cell lymphoma (ENKTL) exhibits an unprecedented degree of global DNA hypermethylation, providing a potent targeted therapy in vivo

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Christoph Weigel, Bethany L. Mundy-Bosse, Yue-Zhong Wu, Kathleen McConnell, Anjali Mishra, Michael A. Caligiuri, Robert A. Baiocchi, Yaso Natkunam, Pierluigi Porcu, Jonathan Brammer, Aharon G. Freud, Christopher C. Oakes
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): LB-102.
https://doi.org/10.1158/1538-7445.AM2019-LB-102
Published: 01 July 2019
View articletitled, Abstract LB-102: Extranodal natural killer/T cell lymphoma (ENKTL) exhibits an unprecedented degree of global DNA hypermethylation, providing a potent targeted therapy in vivo
Journal Articles

Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia

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Valentina Minieri, Marco De Dominici, Patrizia Porazzi, Samanta A. Mariani, Orietta Spinelli, Alessandro Rambaldi, Luke F. Peterson, Pierluigi Porcu, Marja T. Nevalainen, Bruno Calabretta
Journal: Cancer Research
Cancer Res (2018) 78 (20): 5793–5807.
https://doi.org/10.1158/0008-5472.CAN-18-0195
Published: 15 October 2018
View articletitled, Targeting STAT5 or STAT5-Regulated Pathways Suppresses Leukemogenesis of Ph+ Acute Lymphoblastic Leukemia
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Includes: Supplementary data
Journal Articles

Abstract 1873: Preclinical activity of tipifarnib in cutaneous T-cell lymphoma

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Rebecca Kohnken, Betina McNeil, Jing Wen, Kathleen McConnell, Francis Burrows, Pierluigi Porcu, Anjali Mishra
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1873.
https://doi.org/10.1158/1538-7445.AM2018-1873
Published: 01 July 2018
View articletitled, Abstract 1873: Preclinical activity of tipifarnib in cutaneous T-cell lymphoma
Journal Articles

Abstract 481: Diminished microRNA-29b results in overexpression of BRD4 and BRD4-regulated oncogenes in cutaneous T-cell lymphoma

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Rebecca Kohnken, Jing Wen, Bethany Mundy-Bosse, Max Yano, Leah Grinshpun, Kathleen McConnell, Ashleigh Keiter, Alex Hartlage, James Bradner, Michael Caligiuri, Pierluigi Porcu, Anjali Mishra
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 481.
https://doi.org/10.1158/1538-7445.AM2017-481
Published: 01 July 2017
View articletitled, Abstract 481: Diminished microRNA-29b results in overexpression of BRD4 and BRD4-regulated oncogenes in cutaneous T-cell lymphoma
Journal Articles

Abstract 3857: Targeting HDAC1 in a novel model of cutaneous T-cell lymphoma.

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Anjali Mishra, Laura Sullivan, Gregory Sams, Jessica Johns, Douglas Curphey, Lauren Falkenberg, Heather Gibson, Shujun Liu, Laura Jaroncyk, Kathleen McConnell, Henry Wong, Krista La Perle, Ramiro Garzon, Guido Marcucci, Pierluigi Porcu, Michael Caligiuri
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3857.
https://doi.org/10.1158/1538-7445.AM2013-3857
Published: 15 April 2013
View articletitled, Abstract 3857: Targeting HDAC1 in a novel model of cutaneous T-cell lymphoma.
Journal Articles

Abstract 2858: A novel mouse model for cutaneous T-cell lymphoma reveals a role for IL-15 and activity of a new oral HDAC inhibitor

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Anjali Mishra, Gregory H. Sams, Jessica Johns, Douglas P. Curphey, Laura A. Sullivan, Lauren G. Falkenberg, Heather Gibson, Shujun Liu, Laura Jaroncyk, William Carson, Samuel K. Kulp, Ching-Shih Chen, Henry K. Wong, Krista La Perle, Pierluigi Porcu, Ramiro Garzon, Guido Marcucci, Michael A. Caligiuri
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2858.
https://doi.org/10.1158/1538-7445.AM2011-2858
Published: 15 April 2011
View articletitled, Abstract 2858: A novel mouse model for cutaneous T-cell lymphoma reveals a role for IL-15 and activity of a new oral HDAC inhibitor
Journal Articles

Abstract #5655: CT-011, a monoclonal PD-1 blocking antibody, enhances natural killer cell activation and cytotoxicity against multiple myeloma

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Don Benson, Jason Chandler, Anjali Mishra, Robert Baiocchi, Jianhua Yu, Tom Liu, Gerard Lozanski, Pierluigi Porcu, Steven Devine, Rinat Rotem-Yehudar, Michael Caligiuri
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5655.
Published: 01 May 2009
View articletitled, Abstract #5655: CT-011, a monoclonal PD-1 blocking antibody, enhances natural killer cell activation and cytotoxicity against multiple myeloma
Journal Articles

Experimental Treatment of Epstein-Barr Virus-associated Primary Central Nervous System Lymphoma

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Sameek Roychowdhury, Ruoqi Peng, Robert A. Baiocchi, Darshna Bhatt, Srinivas Vourganti, John Grecula, Nilendu Gupta, Charles F. Eisenbeis, Gerard J. Nuovo, Weilian Yang, Petra Schmalbrock, Amy Ferketich, Melvin Moeschberger, Pierluigi Porcu, Rolf F. Barth, Michael A. Caligiuri
Journal: Cancer Research
Cancer Res (2003) 63 (5): 965–971.
Published: 01 March 2003
View articletitled, Experimental Treatment of Epstein-Barr Virus-associated Primary Central Nervous System Lymphoma
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Journal Articles

Inhibition of Cellular Proliferation by Peptide Analogues of Insulin-like Growth Factor 1

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Zbigniew Pietrzkowski, Dorothee Wernicke, Pierluigi Porcu, Bradford A. Jameson, Renato Baserga
Journal: Cancer Research
Cancer Res (1992) 52 (23): 6447–6451.
Published: 01 December 1992
View articletitled, Inhibition of Cellular Proliferation by Peptide Analogues of Insulin-like Growth Factor 1
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Journal Articles

The Protooncogene c-myb Increases the Expression of Insulin-like Growth Factor 1 and Insulin-like Growth Factor 1 Receptor Messenger RNAs by a Transcriptional Mechanism

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Krzysztof Reiss, Andres Ferber, Salvatore Travali, Pierluigi Porcu, Paul D. Phillips, Renato Baserga
Journal: Cancer Research
Cancer Res (1991) 51 (21): 5997–6000.
Published: 01 November 1991
View articletitled, The Protooncogene c-myb Increases the Expression of Insulin-like Growth Factor 1 and Insulin-like Growth Factor 1 Receptor Messenger RNAs by a Transcriptional Mechanism
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Journal Articles

Interleukin 3-dependent Proliferation of the Human MO-7e Cell Line Is Supported by Discrete Activation of Late G1 Genes

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Gian Carlo Avanzi, Pierluigi Porcu, Maria Felice Brizzi, Dario Ghigo, Amalia Bosia, Luigi Pegoraro
Journal: Cancer Research
Cancer Res (1991) 51 (6): 1741–1743.
Published: 01 March 1991
View articletitled, Interleukin 3-dependent Proliferation of the Human MO-7e Cell Line Is Supported by Discrete Activation of Late G1 Genes
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