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Journal Articles

Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling

Free
Claudio Tripodo, Alessia Burocchi, Pier Paolo Piccaluga, Claudia Chiodoni, Paola Portararo, Barbara Cappetti, Laura Botti, Alessandro Gulino, Alessandro Isidori, Arcangelo Liso, Giuseppe Visani, Maria Paola Martelli, Brunangelo Falini, Pier Paolo Pandolfi, Mario P. Colombo, Sabina Sangaletti
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (13): 3685–3699.
https://doi.org/10.1158/0008-5472.CAN-17-1098
Published: 02 July 2017
View articletitled, Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling
Open the PDF for Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling in another window
Includes: Supplementary data
Journal Articles

Abstract 2362: Identification and characterization of pathogenetic pathways and potential therapeutic targets in tumors derived from histiocytes and follicular dendritic cells

Free
Pier-Paolo Piccaluga, Maura Rossi, Giovanna Motta, Sylvia Hartmann, Claudia Doering, Fabio Fuligni, Claudio Agostinelli, Maria Rosaria Sapienza, Maria Antonella Laginestra, Federica Melle, Maryam Etebari, Mohsen Navari, Anna Gazzola, Claudia Mannu, Clara Bertuzzi, Claudio Tripodo, Martin L. Hansmann, Fabio Facchetti, Stefano A Pileri
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2362.
https://doi.org/10.1158/1538-7445.AM2014-2362
Published: 01 October 2014
View articletitled, Abstract 2362: Identification and characterization of pathogenetic pathways and potential therapeutic targets in tumors derived from histiocytes and follicular dendritic cells
Journal Articles

Abstract 5173: Identification of single-nucleotide variants by high-throughput RNA sequencing in endemic Burkitt Lymphoma

Free
Maria Antonella Laginestra, Francesco Abate, Maryam Etebari, Giulia D. Falco, Fabio Fuligni, Maura Rossi, Sakellarios Zairis, Maria Rosaria Sapienza, Anna Gazzola, Claudia Mannu, Federica Melle, Claudio Agostinelli, Mohsen Navari, Cristiana Bellan, Sara Gazaneo, Lucia Mundo, Martin Ogwang, Valeria Calbi, Lorenzo Leoncini, Stefano A. Pileri, Raul Rabadan, Pier Paolo Piccaluga
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 5173.
https://doi.org/10.1158/1538-7445.AM2014-5173
Published: 01 October 2014
View articletitled, Abstract 5173: Identification of single-nucleotide variants by high-throughput RNA sequencing in endemic Burkitt Lymphoma
Journal Articles

Abstract 1951: miRNA expression profile of Blastic plasmacytoid dendritic cell neoplasm.

Free
Maria Rosaria Sapienza, Fabio Fuligni, Maria Antonella Laginestra, Maura Rossi, Luciano Cascione, Alessandro Laganà, Claudio Agostinelli, Maryam Etebari, Anna Gazzola, Claudia Mannu, Elena Sabattini, Francesco Bacci, Carlo Maria Croce, Stefano Aldo Pileri, Pier Paolo Piccaluga
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 1951.
https://doi.org/10.1158/1538-7445.AM2013-1951
Published: 15 April 2013
View articletitled, Abstract 1951: miRNA expression profile of Blastic plasmacytoid dendritic cell neoplasm.
Journal Articles

Abstract 5275: miRNA profiling of peripheral T-cell lymphomas.

Free
Maria Antonella Laginestra, Fabio Fuligni, Maura Rossi, Davide Gibellini, Maria Rosaria Sapienza, Anna Gazzola, Claudia Mannu, Elena Sabattini, Francesco Bacci, Claudio Agostinelli, Stefano Aldo Pileri, Pier Paolo Piccaluga
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 5275.
https://doi.org/10.1158/1538-7445.AM2013-5275
Published: 15 April 2013
View articletitled, Abstract 5275: miRNA profiling of peripheral T-cell lymphomas.
Journal Articles

Abstract 5032: New insights of miR-221 and miR-222 cluster functions in Burkitt lymphoma.

Free
Jessica Consiglio, Luciana De Luca, Mario Acunzo, Marco Galasso, Alberto Rocci, Maria-Rosaria Sapienza, Pier Paolo Piccaluga, Andrea Vecchione, Nicola Zanesi, Stefano Volinia, Carlo Maria Croce, Flavia Pichiorri
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 5032.
https://doi.org/10.1158/1538-7445.AM2012-5032
Published: 15 April 2012
View articletitled, Abstract 5032: New insights of miR-221 and miR-222 cluster functions in Burkitt lymphoma.
Journal Articles

Abstract 2997: Peripheral T-cell lymphomas not otherwise specified correspond to distinct mature T-cell populations basing on the global gene expression profile

Free
Pier-Paolo Piccaluga, Claudio Agostinelli, Maura Rossi, Claudio Tripodo, Davide Gibellini, Maria Rosaria Sapienza, Maria-Antonella Laginestra, Anna Gazzola, Stefano Aldo Pileri
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 2997.
https://doi.org/10.1158/1538-7445.AM2012-2997
Published: 15 April 2012
View articletitled, Abstract 2997: Peripheral T-cell lymphomas not otherwise specified correspond to distinct mature T-cell populations basing on the global gene expression profile
Journal Articles

Abstract 4575: Three-gene diagnostic classifier for ALK negative ALCL

Free
Elisa Pellegrino, Elisabetta Mereu, Luca Agnelli, Tania Limongi, Ivo Kwee, Javeed Iqbal, Pier Paolo Piccaluga, Antonino Neri, John C Chan, Stefano Pileri, Francesco Bertoni, Giorgio Inghirami, Roberto Piva
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 4575.
https://doi.org/10.1158/1538-7445.AM2012-4575
Published: 15 April 2012
View articletitled, Abstract 4575: Three-gene diagnostic classifier for ALK negative ALCL
Journal Articles

Abstract #1287: IKZF1 (Ikaros) Deletions are a frequent event in BCR-ABL1 Positive Acute Lymphoblastic Leukemia (ALL) and are associated with an impaired B-cell differentiation and poor outcome: A GIMEMA ALL Working Party Report

Free
Ilaria Iacobucci, Annalisa Lonetti, Anna Ferrari, Clelia Tiziana Storlazzi, Emanuela Ottaviani, Sabina Chiaretti, Monica Messina, Daniela Cilloni, Carmen Baldazzi, Cristina Papayannidis, Francesca Messa, Annalisa Astolfi, Luciana Impera, Antonella Vitale, Francesca Arruga, Fabrizio Pane, Pier Paolo Piccaluga, Sabrina Colarossi, Simona Soverini, Marco Vignetti, Stefania Paolini, Giuseppe Saglio, Michele Baccarani, Robin Foà, Giovanni Martinelli
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1287.
Published: 01 May 2009
View articletitled, Abstract #1287: IKZF1 (Ikaros) Deletions are a frequent event in BCR-ABL1 Positive Acute Lymphoblastic Leukemia (ALL) and are associated with an impaired B-cell differentiation and poor outcome: A GIMEMA ALL Working Party Report
Journal Articles

Abstract #743: RASGRP1/APTX ratio is a strong biomarker which predicts response to therapy with Tipifarnib plus Bortezomib in elderly patients with Acute Myeloid Leukemia (AML)

Free
Cristina Papayannidis, Stefania Paolini, Emanuela Ottaviani, Federica Salmi, Barbara Lama, Antonio Curti, Ilaria Iacobucci, Sarah Parisi, Cristina Clissa, Pier Paolo Piccaluga, Daniela Cilloni, Giuseppe Saglio, Anna Candoni, Fortunato Morabito, Carlo Finelli, Nicola Vianelli, Mitch Raponi, Massimo Serra, Michele Baccarani, Giovanni Martinelli
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 743.
Published: 01 May 2009
View articletitled, Abstract #743: RASGRP1/APTX ratio is a strong biomarker which predicts response to therapy with Tipifarnib plus Bortezomib in elderly patients with Acute Myeloid Leukemia (AML)
Journal Articles

Abstract #2540: PDGFRA activity deregulation in PTCL/NOS is a consequence of miRNA deregulation and autocrine loop sustainment

Free
Pier-Paolo Piccaluga, Maura Rossi, Giulia De Falco, Aurora Esposito, Pier Luigi Tazzari, Francesca Ricci, Claudio Agostinelli, Simona Righi, Anna Gazzola, Philip went, Francesco Alviano, Anna Luzzi, Federica Morettini, Gian Paolo Bagnara, Stefano Lazzi, Pier Luigi Zinzani, Lorenzo Leoncini, Stefano Pileri
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 2540.
Published: 01 May 2009
View articletitled, Abstract #2540: PDGFRA activity deregulation in PTCL/NOS is a consequence of miRNA deregulation and autocrine loop sustainment
Journal Articles

Abstract #5619: Expression of different isoforms of the B-cell mutator activation-induced cytidine deaminase (AID) in BCR-ABL1-Positive Acute Lymphoblastic Leukemia (ALL) Patients

Free
Annalisa Lonetti, Ilaria Iacobucci, Anna Ferrari, Monica Messina, Daniela Cilloni, Simona Soverini, Sabina Chiaretti, Emanuela Ottaviani, Nicoletta Testoni, Cristina Papayannidis, Francesca Messa, Federica Salmi, Antonella Vitale, Francesca Arruga, Fabrizio Pane, Pier Paolo Piccaluga, Alessandra Gnani, Stefania Paolini, Carla De Giovanni, Giuseppe Saglio, Michele Baccarani, Robin Foà, Giovanni Martinelli
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 5619.
Published: 01 May 2009
View articletitled, Abstract #5619: Expression of different isoforms of the B-cell mutator activation-induced cytidine deaminase (AID) in BCR-ABL1-Positive Acute Lymphoblastic Leukemia (ALL) Patients
Journal Articles

Genome wide analysis of Philadelphia positive (Ph+) acute lymphoblastic leukemia (ALL) reveals a recurring deletion of VPREB1 gene which affects B-cell differentiation

Free
Francesco De Rosa, Ilaria Iacobucci, Emanuela Ottaviani, Annalisa Astolfi, Annalisa Lonetti, Nicoletta Testoni, Tiziana Storlazzi, Luciana Impera, Simona Soverini, Stefania Paolini, Pier Paolo Piccaluga, Cristina Papayannidis, Panagiota Giannoulia, Daniela Cilloni, Andrea Pession, Fabrizio Pane, Antonella Vitale, Robin Foa, Michele Baccarani, Giovanni Martinelli
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1462.
Published: 01 May 2008
View articletitled, Genome wide analysis of Philadelphia positive (Ph+) acute lymphoblastic leukemia (ALL) reveals a recurring deletion of VPREB1 gene which affects B-cell differentiation
Journal Articles

High-resolution genomic profiling of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) patients identified novel recurrent copy number variations involved in both pathogenesis and resistance to tyrosine kinase inhibitors

Free
Ilaria Iacobucci, Emanuela Ottaviani, Annalisa Astolfi, Francesco De Rosa, Annalisa Lonetti, Nicoletta Testoni, Tiziana Storlazzi, Luciana Impera, Simona Soverini, Stefania Paolini, Pier Paolo Piccaluga, Cristina Papayannidis, Panagiota Giannoulia, Daniela Cilloni, Andrea Pession, Fabrizio Pane, Antonella Vitale, Robin Foa, Michele Baccarani, Giovanni Martinelli
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 2213.
Published: 01 May 2008
View articletitled, High-resolution genomic profiling of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) patients identified novel recurrent copy number variations involved in both pathogenesis and resistance to tyrosine kinase inhibitors
Journal Articles

The expression signature of anaplastic large cell lymphomas: From cell lines to primary tumors

Free
Elisa Pellegrino, Luca Agnelli, Ilaria Tamagno, Luigi Ferrantino, Gabriella Cagnoni, Pier Paolo Piccaluga, Stefano Pileri, Cristiane De Wolf-Peeters, Antonino Neri, Giorgio Inghirami, Roberto Piva
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): LB-281.
Published: 01 May 2008
View articletitled, The expression signature of anaplastic large cell lymphomas: From cell lines to primary tumors
Journal Articles

The Bcr-Abl kinase promotes aberrant expression of spliced oncogenic Ikaros isoforms in Philadelphia (Ph) positive acute lymphoblastic leukemia (ALL) patients treated with tyrosine kinase inhibitors

Free
Ilaria Iacobucci, Annalisa Lonetti, Emanuela Ottaviani, Daniela Cilloni, Francesca Messa, Stefania Paolini, Cristina Papayannidis, Pier Paolo Piccaluga, Panagiota Giannoulia, Simona Soverini, Marilina Amabile, Giuseppe Saglio, Fabrizio Pane, Giorgio Berton, Anna Baruzzi, Antonella Vitale, Robin Foa, Michele Baccarani, Giovanni Martinelli
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 5515.
Published: 01 May 2008
View articletitled, The Bcr-Abl kinase promotes aberrant expression of spliced oncogenic Ikaros isoforms in Philadelphia (Ph) positive acute lymphoblastic leukemia (ALL) patients treated with tyrosine kinase inhibitors
Journal Articles

Gene Expression Analysis of Angioimmunoblastic Lymphoma Indicates Derivation from T Follicular Helper Cells and Vascular Endothelial Growth Factor Deregulation

Free
Pier Paolo Piccaluga, Claudio Agostinelli, Andrea Califano, Antonino Carbone, Luca Fantoni, Sergio Ferrari, Anna Gazzola, Annunziata Gloghini, Simona Righi, Maura Rossi, Enrico Tagliafico, Pier Luigi Zinzani, Simonetta Zupo, Michele Baccarani, Stefano A. Pileri
Journal: Cancer Research
Cancer Res (2007) 67 (22): 10703–10710.
https://doi.org/10.1158/0008-5472.CAN-07-1708
Published: 15 November 2007
View articletitled, Gene Expression Analysis of Angioimmunoblastic Lymphoma Indicates Derivation from T Follicular Helper Cells and Vascular Endothelial Growth Factor Deregulation
Open the PDF for Gene Expression Analysis of Angioimmunoblastic Lymphoma Indicates Derivation from T Follicular Helper Cells and Vascular Endothelial Growth Factor Deregulation in another window
Includes: Supplementary data
Journal Articles

Expression of a dominant-negative IKAROS splice variant IK6 in Ph-positive acute lymphoblastic leukemia: Implications for a new mechanisms     of resistance to tyrosine kinase inhibitors

Free
Giovanni Martinelli, Ilaria Iacobucci, Simona Soverini, Emanuela Ottaviani, Stefania Paolini, Pier Paolo Piccaluga, Tiziana Grafone, Rondoni Michela, Marilina Amabile, Angela Poerio, Sabrina Colarossi, Alessandra Gnani, Daniela Cilloni, Giuseppe Saglio, Fabrizio Pane, Gianantonio Rosti, Michele Baccarani
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2638.
Published: 01 May 2007
View articletitled, Expression of a dominant-negative IKAROS splice variant IK6 in Ph-positive acute lymphoblastic leukemia: Implications for a new mechanisms     of resistance to tyrosine kinase inhibitors
Journal Articles

Mutations at contact residues in the ATP-binding site are the main cause of upfront or acquired resistance to dasatinib in Philadelphia chromosome-positive (Ph+) leukemia patients

Free
Simona Soverini, Sabrina Colarossi, Alessandra Gnani, Fausto Castagnetti, Gianantonio Rosti, Costanza Bosi, Stefania Paolini, Michela Rondoni, Pier Paolo Piccaluga, Francesca Palandri, Panagiota Giannoulia, Giulia Marzocchi, Simona Luatti, Elisabetta Abruzzese, Ilaria Iacobucci, Nicoletta Testoni, Michele Baccarani, Pier Luigi Lollini, Giovanni Martinelli
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 2636.
Published: 01 May 2007
View articletitled, Mutations at contact residues in the ATP-binding site are the main cause of upfront or acquired resistance to dasatinib in Philadelphia chromosome-positive (Ph+) leukemia patients
Journal Articles

Imatinib mesylate can induce molecular complete remission in idiopathic hypereosinophilic syndrome (HES): A phase II multicentric Italian clinical trial

Free
Giovanni Martinelli, Daniela Cilloni, Michela Rondoni, Francesca Messa, Emanuela Ottaviani, Enrico Gottardi, Pier Paolo Piccaluga, Michele Malagola, Simona Soverini, Serena Merante, Giuliana Alimena, Costanza Bosi, Antonio Devivo, Gianantonio Rosti, Giugliano Emilia, Fabrizio Pane, Barbara Izzo, Nicoletta Testoni, Stefania Paolini, Francesca Rancati, Renato Bassan, Cristina Mecucci, Michele Baccarani, Giuseppe Saglio
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 274–275.
Published: 15 April 2006
View articletitled, Imatinib mesylate can induce molecular complete remission in idiopathic hypereosinophilic syndrome (HES): A phase II multicentric Italian clinical trial