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Pier Paolo Pandolfi
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Journal Articles

Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma

Open Access
Shawn M. Davidson, Daniel R. Schmidt, Julia E. Heyman, James P. O'Brien, Amy C. Liu, William J. Israelsen, Talya L. Dayton, Raghav Sehgal, Roderick T. Bronson, Elizaveta Freinkman, Howard H. Mak, Giuseppe Nicolò Fanelli, Scott Malstrom, Gary Bellinger, Arkaitz Carracedo, Pier Paolo Pandolfi, Kevin D. Courtney, Abhishek Jha, Ronald A. DePinho, James W. Horner, Craig J. Thomas, Lewis C. Cantley, Massimo Loda, Matthew G. Vander Heiden
Journal: Cancer Research
Cancer Res (2022) 82 (13): 2403–2416.
https://doi.org/10.1158/0008-5472.CAN-21-2352
Published: 05 July 2022
View articletitled, Pyruvate Kinase M1 Suppresses Development and Progression of Prostate Adenocarcinoma
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Includes: Supplementary data
Journal Articles

Abstract 1694: CHIP and AML mutations dictate the composition of hematopoietic microenvironments

Free
Ryan R. Posey, Lourdes M. Mendez, Jonathan D. Lee, John G. Clohessy, Pier Paolo Pandolfi
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 1694.
https://doi.org/10.1158/1538-7445.AM2020-1694
Published: 15 August 2020
View articletitled, Abstract 1694: CHIP and AML mutations dictate the composition of hematopoietic microenvironments
Journal Articles

Abstract 1403: Modeling of Abi1 loss using spheroid cultures to investigate mechanisms of prostate tumorigenesis

Free
Disharee Das, Ming Chen, Claudia Mondragon, Dawn Post, Alexander Nappi, Heidi Hehnly, Anita Hryniewicz-Jankowska, Pier Paolo Pandolfi, Gennady Bratslavsky, Leszek Kotula
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1403.
https://doi.org/10.1158/1538-7445.AM2018-1403
Published: 01 July 2018
View articletitled, Abstract 1403: Modeling of Abi1 loss using spheroid cultures to investigate mechanisms of prostate tumorigenesis
Journal Articles

Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling

Free
Claudio Tripodo, Alessia Burocchi, Pier Paolo Piccaluga, Claudia Chiodoni, Paola Portararo, Barbara Cappetti, Laura Botti, Alessandro Gulino, Alessandro Isidori, Arcangelo Liso, Giuseppe Visani, Maria Paola Martelli, Brunangelo Falini, Pier Paolo Pandolfi, Mario P. Colombo, Sabina Sangaletti
Journal: Cancer Research
Series: Author Choice
Cancer Res (2017) 77 (13): 3685–3699.
https://doi.org/10.1158/0008-5472.CAN-17-1098
Published: 02 July 2017
View articletitled, Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling
Open the PDF for Persistent Immune Stimulation Exacerbates Genetically Driven Myeloproliferative Disorders via Stromal Remodeling in another window
Includes: Supplementary data
Journal Articles

Abstract B48: Prostate cancer pre-treatment with nanoformulated Olaparib overcomes radiation resistance

Free
Anne L. van de Ven, Shifalika Tangutoori, Paige Baldwin, Ju Qiao, Codi Gharagouzloo, Nina Seitzer, John Clohessy, Houari Korideck, G. Mike Makrigiorgos, Robert Cormack, Pier Paolo Pandolfi, Srinivas Sridhar
Journal: Cancer Research
Cancer Res (2017) 77 (2_Supplement): B48.
https://doi.org/10.1158/1538-7445.EPSO16-B48
Published: 16 January 2017
View articletitled, Abstract B48: Prostate cancer pre-treatment with nanoformulated Olaparib overcomes radiation resistance
Journal Articles

Abstract 4979: Cabozantinib eradicates advanced murine prostate cancer by activating neutrophil-mediated anti-tumor innate immunity

Free
Akash Patnaik, Kenneth D. Swanson, Eva Csizmadia, Marina P. Gehring, Katja Helenius, Athalia R. Pyzer, Lily C. Wang, Jesse Novak, Olivier Elemento, Thomas B. Thornley, John M. Asara, John G. Clohessy, Kathy Kelly, Pier Paolo Pandolfi, Jacalyn M. Rosenblatt, David E. Avigan, Huihui Ye, Sabina Signoretti, Steven P. Balk, Lewis C. Cantley
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 4979.
https://doi.org/10.1158/1538-7445.AM2016-4979
Published: 15 July 2016
View articletitled, Abstract 4979: Cabozantinib eradicates advanced murine prostate cancer by activating neutrophil-mediated anti-tumor innate immunity
Journal Articles

Abstract 601: Essential role of LRF in mesenchymal stem cell differentiation and tumorigenesis through Dlk1 and Sox9 repression

Free
Jlenia Guarnerio, Andrea Lunardi, Pier Paolo Pandolfi
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 601.
https://doi.org/10.1158/1538-7445.AM2014-601
Published: 01 October 2014
View articletitled, Abstract 601: Essential role of LRF in mesenchymal stem cell differentiation and tumorigenesis through Dlk1 and Sox9 repression
Journal Articles

Abstract IA12: The noncoding RNA revolution in cancer research

Free
Pier Paolo Pandolfi
Journal: Cancer Research
Cancer Res (2013) 73 (19_Supplement): IA12.
https://doi.org/10.1158/1538-7445.FBCR13-IA12
Published: 15 May 2014
View articletitled, Abstract IA12: The noncoding RNA revolution in cancer research
Journal Articles

Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth

Free
Barbara Wegiel, David Gallo, Eva Csizmadia, Clair Harris, John Belcher, Gregory M. Vercellotti, Nuno Penacho, Pankaj Seth, Vikas Sukhatme, Asif Ahmed, Pier Paolo Pandolfi, Leszek Helczynski, Anders Bjartell, Jenny Liao Persson, Leo E. Otterbein
Journal: Cancer Research
Cancer Res (2013) 73 (23): 7009–7021.
https://doi.org/10.1158/0008-5472.CAN-13-1075
Published: 01 December 2013
View articletitled, Carbon Monoxide Expedites Metabolic Exhaustion to Inhibit Tumor Growth
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Includes: Supplementary data
Journal Articles

MUC1 Is a Potential Target for the Treatment of Acute Myeloid Leukemia Stem Cells

Free
Dina Stroopinsky, Jacalyn Rosenblatt, Keisuke Ito, Heidi Mills, Li Yin, Hasan Rajabi, Baldev Vasir, Turner Kufe, Katarina Luptakova, Jon Arnason, Caterina Nardella, James D. Levine, Robin M. Joyce, Ilene Galinsky, Yoram Reiter, Richard M. Stone, Pier Paolo Pandolfi, Donald Kufe, David Avigan
Journal: Cancer Research
Cancer Res (2013) 73 (17): 5569–5579.
https://doi.org/10.1158/0008-5472.CAN-13-0677
Published: 02 September 2013
View articletitled, MUC1 Is a Potential Target for the Treatment of Acute Myeloid Leukemia Stem Cells
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Includes: Supplementary data
Journal Articles

Abstract IA16: The ceRNA hypothesis and the non-coding revolution in cancer research and therapy

Free
Pier Paolo Pandolfi
Journal: Cancer Research
Cancer Res (2012) 72 (2_Supplement): IA16.
https://doi.org/10.1158/1538-7445.NONRNA12-IA16
Published: 03 April 2013
View articletitled, Abstract IA16: The ceRNA hypothesis and the non-coding revolution in cancer research and therapy
Journal Articles

Abstract LB-365: Effective use of PI3K/MTOR and MEK inhibitors prior to hormone ablative therapy in PTEN-loss driven murine prostate cancer

Free
Akash Patnaik, Kevin Courtney, Kyle Robichaud, Gary Bellinger, Caterina Nardella, Sabina Signoretti, Richard Wooster, Pier Paolo Pandolfi, Lewis Cantley
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): LB-365.
https://doi.org/10.1158/1538-7445.AM2012-LB-365
Published: 15 April 2012
View articletitled, Abstract LB-365: Effective use of PI3K/MTOR and MEK inhibitors prior to hormone ablative therapy in PTEN-loss driven murine prostate cancer
Journal Articles

Differential Expression of S6K2 Dictates Tissue-Specific Requirement for S6K1 in Mediating Aberrant mTORC1 Signaling and Tumorigenesis

Free
Caterina Nardella, Andrea Lunardi, Giuseppe Fedele, John G. Clohessy, Andrea Alimonti, Sara C. Kozma, George Thomas, Massimo Loda, Pier Paolo Pandolfi
Journal: Cancer Research
Cancer Res (2011) 71 (10): 3669–3675.
https://doi.org/10.1158/0008-5472.CAN-10-3962
Published: 15 May 2011
View articletitled, Differential Expression of S6K2 Dictates Tissue-Specific Requirement for S6K1 in Mediating Aberrant mTORC1 Signaling and Tumorigenesis
Open the PDF for Differential Expression of S6K2 Dictates Tissue-Specific Requirement for S6K1 in Mediating Aberrant mTORC1 Signaling and Tumorigenesis in another window
Includes: Supplementary data
Journal Articles

PTEN Level in Tumor Suppression: How Much Is Too Little?

Free
Arkaitz Carracedo, Andrea Alimonti, Pier Paolo Pandolfi
Journal: Cancer Research
Cancer Res (2011) 71 (3): 629–633.
https://doi.org/10.1158/0008-5472.CAN-10-2488
Published: 01 February 2011
View articletitled, PTEN Level in Tumor Suppression: How Much Is Too Little?
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Journal Articles

Twenty-First Annual Pezcoller Symposium: Unconventional Therapeutic Targets in Cancer

Free
Enrico Mihich, Pier Paolo Pandolfi, David Livingston
Journal: Cancer Research
Cancer Res (2010) 70 (1): 14–17.
https://doi.org/10.1158/0008-5472.CAN-09-3368
Published: 04 January 2010
View articletitled, Twenty-First Annual Pezcoller Symposium: Unconventional Therapeutic Targets in Cancer
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Journal Articles

Catalytic forms of human kallikrein-related peptidase 2 (hK2) promote cellular migration and invasion in vitro

Free
Sven Wenske, Todd Hricik, Amine Benchickh, Carlos Cordon-Cardo, Pier-Paolo Pandolfi, Glenn Heller, Howard Scher, Peter Scardino, Brett Carver, Hans Lilja
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 1156.
Published: 01 May 2008
View articletitled, Catalytic forms of human kallikrein-related peptidase 2 (hK2) promote cellular migration and invasion in vitro
Journal Articles

Identification of S664 TSC2 Phosphorylation as a Marker for Extracellular Signal-Regulated Kinase–Mediated mTOR Activation in Tuberous Sclerosis and Human Cancer

Free
Li Ma, Julie Teruya-Feldstein, Pauline Bonner, Rosa Bernardi, David Neal Franz, David Witte, Carlos Cordon-Cardo, Pier Paolo Pandolfi
Journal: Cancer Research
Cancer Res (2007) 67 (15): 7106–7112.
https://doi.org/10.1158/0008-5472.CAN-06-4798
Published: 01 August 2007
View articletitled, Identification of S664 TSC2 Phosphorylation as a Marker for Extracellular Signal-Regulated Kinase–Mediated mTOR Activation in Tuberous Sclerosis and Human Cancer
Open the PDF for Identification of S664 TSC2 Phosphorylation as a Marker for Extracellular Signal-Regulated Kinase–Mediated mTOR Activation in Tuberous Sclerosis and Human Cancer in another window
Journal Articles

The Transcription Factor Pokemon: A New Key Player in Cancer Pathogenesis

Free
Takahiro Maeda, Robin M. Hobbs, Pier Paolo Pandolfi
Journal: Cancer Research
Cancer Res (2005) 65 (19): 8575–8578.
https://doi.org/10.1158/0008-5472.CAN-05-1055
Published: 03 October 2005
View articletitled, The Transcription Factor Pokemon: A New Key Player in Cancer Pathogenesis
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Journal Articles

Somatic Induction of Pten Loss in a Preclinical Astrocytoma Model Reveals Major Roles in Disease Progression and Avenues for Target Discovery and Validation

Free
Andrew Xiao, Chaoying Yin, Chunyu Yang, Antonio Di Cristofano, Pier Paolo Pandolfi, Terry Van Dyke
Journal: Cancer Research
Cancer Res (2005) 65 (12): 5172–5180.
https://doi.org/10.1158/0008-5472.CAN-04-3902
Published: 15 June 2005
View articletitled, Somatic Induction of Pten Loss in a Preclinical Astrocytoma Model Reveals Major Roles in Disease Progression and Avenues for Target Discovery and Validation
Open the PDF for Somatic Induction of Pten Loss in a Preclinical Astrocytoma Model Reveals Major Roles in Disease Progression and Avenues for Target Discovery and Validation in another window
Journal Articles

4-Oxoretinol, a Metabolite of Retinol in the Human Promyelocytic Leukemia Cell Line NB4, Induces Cell Growth Arrest and Granulocytic Differentiation

Free
Teresa N. Faria, Roberta Rivi, Fadila Derguini, Pier Paolo Pandolfi, Lorraine J. Gudas
Journal: Cancer Research
Cancer Res (1998) 58 (9): 2007–2013.
Published: 01 May 1998
View articletitled, 4-Oxoretinol, a Metabolite of Retinol in the Human Promyelocytic Leukemia Cell Line NB4, Induces Cell Growth Arrest and Granulocytic Differentiation
Open the PDF for 4-Oxoretinol, a Metabolite of Retinol in the Human Promyelocytic Leukemia Cell Line NB4, Induces Cell Growth Arrest and Granulocytic Differentiation in another window