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Journal Articles

Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody–Drug Conjugates

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Hui Zhao, John Atkinson, Sara Gulesserian, Zhilan Zeng, Jenny Nater, Jimmy Ou, Peng Yang, Karen Morrison, Jeffrey Coleman, Faisal Malik, Pia Challita-Eid, Sher Karki, Hector Aviña, René Hubert, Linnette Capo, Josh Snyder, Sung-Ju Moon, Roland Luethy, Brian A. Mendelsohn, David R. Stover, Fernando Doñate
Journal: Cancer Research
Cancer Res (2018) 78 (8): 2115–2126.
https://doi.org/10.1158/0008-5472.CAN-17-3202
Published: 12 April 2018
View articletitled, Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody–Drug Conjugates
Open the PDF for Modulation of Macropinocytosis-Mediated Internalization Decreases Ocular Toxicity of Antibody–Drug Conjugates in another window
Includes: Supplementary data
Journal Articles

Abstract 2650: Ags67e, an anti-cd37 monomethyl auristatin e antibody (mmae) drug conjugate as a potential therapeutic for non-hodgkin's lymphoma, chronic lymphocytic leukemia and acute myeloid leukemia

Free
Daniel S. Pereira, Claudia Guevara, Alla Verlinsky, Cyrus Virata, J Hsu Ssucheng, Zili An, Chungying Zhang, Nick Dinh, Hector Avina, Lisa Do, Sher Karki, Joseph Abad, Peng Yang, Jimmy Ou, Karen Morrison, Sing-Ju Moon, Faisal Malik, Liqing Jin, Michael Choi, Christina Wu, Banmeet Anand, Scott Cooper, Ingrid Joseph, Xiao-Chi Jia, Kendall Morrison, Pia Challita-Eid, Fernando Donate, Thomas Kipps, John Dick, David Stover
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 2650.
https://doi.org/10.1158/1538-7445.AM2014-2650
Published: 01 October 2014
View articletitled, Abstract 2650: Ags67e, an anti-cd37 monomethyl auristatin e antibody (mmae) drug conjugate as a potential therapeutic for non-hodgkin's lymphoma, chronic lymphocytic leukemia and acute myeloid leukemia
Journal Articles

Abstract 2047: Discovery and molecular characterization of AGS-15/SLITRK6 as a novel target for antibody-mediated therapeutic development in bladder cancer.

Free
Yuriy Shostak, Suzanne Said, Deanna L. Russell, Michael D. Mattie, Mi Sook Chang, Ashley Christensen, Karen Morrison, Kendall Morrison, David Stover, Pia Challita-Eid
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 2047.
https://doi.org/10.1158/1538-7445.AM2013-2047
Published: 15 April 2013
View articletitled, Abstract 2047: Discovery and molecular characterization of AGS-15/SLITRK6 as a novel target for antibody-mediated therapeutic development in bladder cancer.
Journal Articles

Abstract 1314: Molecular profiling and characterization of patient-derived human pancreatic tumor xenograft models, and application for drug discovery and preclinical development of cancer therapeutics

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Michael D. Mattie, Mi Sook Chang, Ashley Christensen, William Yeh, Suzanne Said, Yuriy Shostak, Linnette Capo, Alla Verlinsky, Zili An, Sathish Kumar-Ganesan, Karen Morrison, Ingrid Joseph, David Stover, Pia Challita-Eid
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1314.
https://doi.org/10.1158/1538-7445.AM2012-1314
Published: 15 April 2012
View articletitled, Abstract 1314: Molecular profiling and characterization of patient-derived human pancreatic tumor xenograft models, and application for drug discovery and preclinical development of cancer therapeutics
Journal Articles

Abstract 1086: Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression

Free
Nandini Rudra-Ganguly, Daulet Satpayev, Christine Lowe, Liping Hu, Bally Randhawa, Mi Sook Chang, Alla Verlinsky, Jeffrey Coleman, Pia Challita-Eid, Peng Yang, Zili An, Karen Morrison, Art Raitano, Daniel S. Pereira, David Stover
Journal: Cancer Research
Cancer Res (2012) 72 (8_Supplement): 1086.
https://doi.org/10.1158/1538-7445.AM2012-1086
Published: 15 April 2012
View articletitled, Abstract 1086: Discoidin domain receptor 1 contributes to tumorigenesis through modulation of TGFBI expression
Journal Articles

Abstract 4566: AGS-1C4D4: A fully human anti-PSCA antibody inhibits tumor formation and metastasis in orthotopic models of pancreatic cancer

Free
Tony Navas, Trisha Haubrich, Jenny Llamas, Hector Avina, Zhang Chunying, Myra Perez, Linnette Capo, Monica Leavitt, Rou-Yu Chen, Alla Verlinsky, Zili An, James Secrest, Nandini Ganguly, Daulet Satpayev, Karen Morrison, Art Raitano, Pia Challita-Eid, Xiao-Chi Jia, Kendall Morrison, Alan Hartford, David Stover
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 4566.
https://doi.org/10.1158/1538-7445.AM2011-4566
Published: 15 April 2011
View articletitled, Abstract 4566: AGS-1C4D4: A fully human anti-PSCA antibody inhibits tumor formation and metastasis in orthotopic models of pancreatic cancer
Journal Articles

Abstract 2832: Development of AGS-22M6E, a novel antibody drug conjugate (ADC) targeting Nectin-4 for the treatment of solid tumors

Free
Daulet Satpayev, Michael Torgov, Peng Yang, Karen Morrison, Yuriy Shostak, Art Raitano, Wendy Liu, Dawn Lortie, Zili An, Linnette Capo, Monica Leavitt, Myra Perez, Alla Verlinsky, Kenna Shirasuna, Hector Avina, Claudia Guevara, Kendall Morrison, Pia Challita-Eid, Xiao-Chi Jia, Jean Gudas, David Stover
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): 2832.
https://doi.org/10.1158/1538-7445.AM2011-2832
Published: 15 April 2011
View articletitled, Abstract 2832: Development of AGS-22M6E, a novel antibody drug conjugate (ADC) targeting Nectin-4 for the treatment of solid tumors
Journal Articles

A human monoclonal antibody directed to a novel target for the treatment of kidney and liver cancers

Free
Steven Kanner, Zili An, Nandini Ganguly, Kendall Morrison, Karen Morrison, Pia Challita-Eid, Arthur Raitano, Daulet Satpaev, Xiao-Chi Jia, Jean Gudas, Aya Jakobovits
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3978.
Published: 01 May 2008
View articletitled, A human monoclonal antibody directed to a novel target for the treatment of kidney and liver cancers
Journal Articles

A novel therapeutic human monoclonal antibody for the treatment of ovarian cancer

Free
Steven Kanner, Zili An, Nandini Ganguly, Kendall Morrison, Karen Morrison, Pia Challita-Eid, Arthur Raitano, Daulet Satpaev, Xiao-Chi Jia, Jean Gudas, Aya Jakobovits
Journal: Cancer Research
Cancer Res (2008) 68 (9_Supplement): 3977.
Published: 01 May 2008
View articletitled, A novel therapeutic human monoclonal antibody for the treatment of ovarian cancer
Journal Articles

Human monoclonal antibodies to a novel kidney cancer antigen inhibit target-induced angiogenesis and tumor cell growth and migration in vitro

Free
Steven Kanner, Nandini Ganguly, Kendall Morrison, Juan Perez-Villar, Karen Morrison, Arthur Raitano, Pia Challita-Eid, Daulet Satpaev, Xiao-Chi Jia, Jean Gudas, Aya Jakobovits
Journal: Cancer Research
Cancer Res (2007) 67 (9_Supplement): 4108.
Published: 01 May 2007
View articletitled, Human monoclonal antibodies to a novel kidney cancer antigen inhibit target-induced angiogenesis and tumor cell growth and migration in vitro