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Philippe Marchetti
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Journal Articles

Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants

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Jérome Kluza, Paola Corazao-Rozas, Yasmine Touil, Manel Jendoubi, Cyril Maire, Pierre Guerreschi, Aurélie Jonneaux, Caroline Ballot, Stéphane Balayssac, Samuel Valable, Aurélien Corroyer-Dulmont, Myriam Bernaudin, Myriam Malet-Martino, Elisabeth Martin de Lassalle, Patrice Maboudou, Pierre Formstecher, Renata Polakowska, Laurent Mortier, Philippe Marchetti
Journal: Cancer Research
Cancer Res (2012) 72 (19): 5035–5047.
https://doi.org/10.1158/0008-5472.CAN-12-0979
Published: 30 September 2012
View article titled, Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants
Open the PDF for Inactivation of the HIF-1α/PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants in another window
Includes: Supplementary data
Journal Articles

Dormant Tumor Cells Develop Cross-Resistance to Apoptosis Induced by CTLs or Imatinib Mesylate via Methylation of Suppressor of Cytokine Signaling 1

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Aurore Saudemont, Abdelbasset Hamrouni, Philippe Marchetti, Jizhong Liu, Nathalie Jouy, Dominique Hetuin, Francesco Colucci, Bruno Quesnel
Journal: Cancer Research
Cancer Res (2007) 67 (9): 4491–4498.
https://doi.org/10.1158/0008-5472.CAN-06-1627
Published: 04 May 2007
View article titled, Dormant Tumor Cells Develop Cross-Resistance to Apoptosis Induced by CTLs or Imatinib Mesylate via Methylation of Suppressor of Cytokine Signaling 1
Open the PDF for Dormant Tumor Cells Develop Cross-Resistance to Apoptosis Induced by CTLs or Imatinib Mesylate via Methylation of Suppressor of Cytokine Signaling 1 in another window
Includes: Supplementary data
Journal Articles

Dormant tumor cells develop cross-resistance to apoptosis induced by CTLs or imatinib mesylate, via methylation of SOCS1

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Aurore Saudemont, Abdelbasset Hamrouni, Philippe Marchetti, Jizhong Liu, Nathalie Jouy, Dominique Hetuin, Bruno Quesnel
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1147.
Published: 15 April 2006
View article titled, Dormant tumor cells develop cross-resistance to apoptosis induced by CTLs or imatinib mesylate, via methylation of SOCS1
Journal Articles

Cancer Cell Mitochondria Are Direct Proapoptotic Targets for the Marine Antitumor Drug Lamellarin D

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Jérôme Kluza, Miguel-Angel Gallego, Anne Loyens, Jean-Claude Beauvillain, José-Maria Fernandez Sousa-Faro, Carmen Cuevas, Philippe Marchetti, Christian Bailly
Journal: Cancer Research
Cancer Res (2006) 66 (6): 3177–3187.
https://doi.org/10.1158/0008-5472.CAN-05-1929
Published: 15 March 2006
View article titled, Cancer Cell Mitochondria Are Direct Proapoptotic Targets for the Marine Antitumor Drug Lamellarin D
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Journal Articles

Direct mitochondrial perturbations induced by the topoisomerase I poison lamellarin D in P388 leukemia cells sensitive and resistant to camptothecin

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Jérôme Kluza, Philippe Marchetti, Amélie Lansiaux, Gabriel Otero, Carmen Cuevas, Christian Bailly
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1125–1126.
Published: 01 April 2004
View article titled, Direct mitochondrial perturbations induced by the topoisomerase I poison lamellarin D in P388 leukemia cells sensitive and resistant to camptothecin
Journal Articles

The Novel Retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene Carboxylic Acid Can Trigger Apoptosis through a Mitochondrial Pathway Independent of the Nucleus

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Philippe Marchetti, Naoufal Zamzami, Bertrand Joseph, Susanna Schraen-Maschke, Claude Méreau-Richard, Paola Costantini, Didier Métivier, Santos A. Susin, Guido Kroemer, Pierre Formstecher
Journal: Cancer Research
Cancer Res (1999) 59 (24): 6257–6266.
Published: 15 December 1999
View article titled, The Novel Retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene Carboxylic Acid Can Trigger Apoptosis through a Mitochondrial Pathway Independent of the Nucleus
Open the PDF for The Novel Retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene Carboxylic Acid Can Trigger Apoptosis through a Mitochondrial Pathway Independent of the Nucleus in another window
Journal Articles

Bcl-2 and Bcl-XL Antagonize the Mitochondrial Dysfunction Preceding Nuclear Apoptosis Induced by Chemotherapeutic Agents

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Didier Decaudin, Stephan Geley, Tamara Hirsch, Maria Castedo, Philippe Marchetti, Antonio Macho, Reinhard Kofler, Guido Kroemer
Journal: Cancer Research
Cancer Res (1997) 57 (1): 62–67.
Published: 01 January 1997
View article titled, Bcl-2 and Bcl-XL Antagonize the Mitochondrial Dysfunction Preceding Nuclear Apoptosis Induced by Chemotherapeutic Agents
Open the PDF for Bcl-2 and Bcl-XL Antagonize the Mitochondrial Dysfunction Preceding Nuclear Apoptosis Induced by Chemotherapeutic Agents in another window
Journal Articles

Apoptosis-associated Derangement of Mitochondrial Function in Cells Lacking Mitochondrial DNA

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Philippe Marchetti, Santos A. Susin, Didier Decaudin, Susana Gamen, Maria Castedo, Tamara Hirsch, Naoufal Zamzami, Javier Naval, Anna Senik, Guido Kroemer
Journal: Cancer Research
Cancer Res (1996) 56 (9): 2033–2038.
Published: 01 May 1996
View article titled, Apoptosis-associated Derangement of Mitochondrial Function in Cells Lacking Mitochondrial DNA
Open the PDF for Apoptosis-associated Derangement of Mitochondrial Function in Cells Lacking Mitochondrial DNA in another window