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Philip J. Burke
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Journal Articles

Bioactivation of 5-(Aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by Human NAD(P)H Quinone Oxidoreductase 2: A Novel Co-substrate-mediated Antitumor Prodrug Therapy

Richard J. Knox, Terence C. Jenkins, Stephen M. Hobbs, Shiuan Chen, Roger G. Melton, Philip J. Burke
Journal: Cancer Research
Cancer Res (2000) 60 (15): 4179–4186.
Published: 01 August 2000
View article titled, Bioactivation of 5-(Aziridin-1-yl)-2,4-dinitrobenzamide (CB 1954) by Human NAD(P)H Quinone Oxidoreductase 2: A Novel Co-substrate-mediated Antitumor Prodrug Therapy
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Journal Articles

ZD2767, an Improved System for Antibody-directed Enzyme Prodrug Therapy That Results in Tumor Regressions in Colorectal Tumor Xenografts

David C. Blakey, Philip J. Burke, David H. Davies, Robert I. Dowell, Simon J. East, Kay P. Eckersley, John E. Fitton, John McDaid, Roger G. Melton, Ion A. Niculescu-Duvaz, Philip E. Pinder, Surinder K. Sharma, Andrew F. Wright, Caroline J. Springer
Journal: Cancer Research
Cancer Res (1996) 56 (14): 3287–3292.
Published: 01 July 1996
View article titled, ZD2767, an Improved System for Antibody-directed Enzyme Prodrug Therapy That Results in Tumor Regressions in Colorectal Tumor Xenografts
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Journal Articles

Changes in Topoisomerase I Levels and Localization during Myeloid Maturation in Vitro and in Vivo

Scott H. Kaufmann, Martin Charron, Philip J. Burke, Judith E. Karp
Journal: Cancer Research
Cancer Res (1995) 55 (6): 1255–1260.
Published: 01 March 1995
View article titled, Changes in Topoisomerase I Levels and Localization during Myeloid Maturation <em>in Vitro</em> and <em>in Vivo</em>
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Journal Articles

Topoisomerase II Levels during Granulocytic Maturation in Vitro and in Vivo

Scott H. Kaufmann, Sharon J. McLaughlin, Michael B. Kastan, Leroy F. Liu, Judith E. Karp, Philip J. Burke
Journal: Cancer Research
Cancer Res (1991) 51 (13): 3534–3543.
Published: 01 July 1991
View article titled, Topoisomerase II Levels during Granulocytic Maturation <em>in Vitro</em> and <em>in Vivo</em>
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Journal Articles

Phase I and Pharmacodynamic Study of Taxol in Refractory Acute Leukemias

Eric K. Rowinsky, Philip J. Burke, Judith E. Karp, Robert W. Tucker, David S. Ettinger, Ross C. Donehower
Journal: Cancer Research
Cancer Res (1989) 49 (16): 4640–4647.
Published: 01 August 1989
View article titled, Phase I and Pharmacodynamic Study of Taxol in Refractory Acute Leukemias
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Journal Articles

Growth Response of Residual Leukemia after Initial Drug Therapy

Judith E. Karp, Philip J. Burke
Journal: Cancer Research
Cancer Res (1986) 46 (8): 4205–4207.
Published: 01 August 1986
View article titled, Growth Response of Residual Leukemia after Initial Drug Therapy
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Journal Articles

Drug Induced Host Factors Which Stimulate Growth of Residual Leukemia in Lewis × Brown Norway F1 (LEW-BN) Rats

Philip J. Burke, Judith E. Karp, Patricia L. Saylor
Journal: Cancer Research
Cancer Res (1986) 46 (4_Part_1): 1813–1816.
Published: 01 April 1986
View article titled, Drug Induced Host Factors Which Stimulate Growth of Residual Leukemia in Lewis × Brown Norway F<sub>1</sub> (LEW-BN) Rats
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Journal Articles

Direct Relationship of Marrow Cell Growth and 1-β-d-Arabinofuranosylcytosine Metabolism1

Judith E. Karp, Ross C. Donehower, Gregory B. Dole, Philip J. Burke
Journal: Cancer Research
Cancer Res (1984) 44 (11): 5046–5050.
Published: 01 November 1984
View article titled, Direct Relationship of Marrow Cell Growth and 1-β-<sc>d</sc>-Arabinofuranosylcytosine Metabolism<sup>1</sup>
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Journal Articles

Correlation of Proliferative and Clonogenic Tumor Cells in Multiple Myeloma

Judith E. Karp, Philip J. Burke, Patricia L. Saylor, Richard L. Humphrey
Journal: Cancer Research
Cancer Res (1984) 44 (9): 4197–4200.
Published: 01 September 1984
View article titled, Correlation of Proliferative and Clonogenic Tumor Cells in Multiple Myeloma
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Journal Articles

Development of a Cell Kinetic Approach to Curative Therapy of Acute Myelocytic Leukemia in Remission Using the Cell Cycle-specific Drug 1-β-d-Arabinofuranosylcytosine in a Rat Model1

William P. Vaughan, Philip J. Burke
Journal: Cancer Research
Cancer Res (1983) 43 (5): 2005–2009.
Published: 01 May 1983
View article titled, Development of a Cell Kinetic Approach to Curative Therapy of Acute Myelocytic Leukemia in Remission Using the Cell Cycle-specific Drug 1-β-<sc>d</sc>-Arabinofuranosylcytosine in a Rat Model<sup>1</sup>
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Journal Articles

Diamine Oxidase as a Plasma Marker of Rat Intestinal Mucosal Injury and Regeneration after Administration of 1-β-d-Arabinofuranosylcytosine1

Gordon D. Luk, William P. Vaughan, Philip J. Burke, Stephen B. Baylin
Journal: Cancer Research
Cancer Res (1981) 41 (6): 2334–2337.
Published: 01 June 1981
View article titled, Diamine Oxidase as a Plasma Marker of Rat Intestinal Mucosal Injury and Regeneration after Administration of 1-β-<sc>d</sc>-Arabinofuranosylcytosine<sup>1</sup>
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Journal Articles

Timed Sequential Therapy of Human Leukemia Based upon the Response of Leukemic Cells to Humoral Growth Factors

Philip J. Burke, Judith E. Karp, Hayden G. Braine, William P. Vaughan
Journal: Cancer Research
Cancer Res (1977) 37 (7_Part_1): 2138–2146.
Published: 01 July 1977
View article titled, Timed Sequential Therapy of Human Leukemia Based upon the Response of Leukemic Cells to Humoral Growth Factors
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Journal Articles

Enhancement of Drug Cytotoxicity by Recruitment of Leukemic Myeloblasts with Humoral Stimulation

Judith E. Karp, Philip J. Burke
Journal: Cancer Research
Cancer Res (1976) 36 (10): 3600–3603.
Published: 01 October 1976
View article titled, Enhancement of Drug Cytotoxicity by Recruitment of Leukemic Myeloblasts with Humoral Stimulation
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Journal Articles

Influence of Humoral Regulators on Proliferation and Maturation of Normal and Leukemic Cells

Judith E. Karp, Philip J. Burke
Journal: Cancer Research
Cancer Res (1976) 36 (5): 1674–1679.
Published: 01 May 1976
View article titled, Influence of Humoral Regulators on Proliferation and Maturation of Normal and Leukemic Cells
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Journal Articles

Factors in Human Serum Affecting the Proliferation of Normal and Leukemic Cells

Philip J. Burke, Charles H. Diggs, Albert H. Owens, Jr.
Journal: Cancer Research
Cancer Res (1973) 33 (4): 800–806.
Published: 01 April 1973
View article titled, Factors in Human Serum Affecting the Proliferation of Normal and Leukemic Cells
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Journal Articles

A Clinical Evaluation of a Prolonged Schedule of Cytosine Arabinoside (NSC 63878)

Philip J. Burke, Albert H. Owens, Jr., Jacob Colsky, Bruce I. Shnider, John H. Edmonson, Albert Schilling, Harvey S. Brodovsky, H. James Wallace, Jr., Thomas C. Hall
Journal: Cancer Research
Cancer Res (1970) 30 (5): 1512–1515.
Published: 01 May 1970
View article titled, A Clinical Evaluation of a Prolonged Schedule of Cytosine Arabinoside (NSC 63878)
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Journal Articles

A Clinical Evaluation of Dose and Schedule of Administration of Cytosine Arabinoside (NSC 63878)

Philip J. Burke, Arthur A. Serpick, Paul P. Carbone, Norman Tarr
Journal: Cancer Research
Cancer Res (1968) 28 (2): 274–279.
Published: 01 February 1968
View article titled, A Clinical Evaluation of Dose and Schedule of Administration of Cytosine Arabinoside (NSC 63878)
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