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Philip B. Paty
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Journal Articles

Abstract 5026: Discovery of oncogenic mediator genes in rectal cancer chemotherapy response using gene expression data from matched tumor and patient-derived organoids

Hanchen Huang, Wini Zambare, Chao Wu, Antonio Colaprico, Janet Alvarez, Min Jung Kim, Aron Bercz, Paulina Bleu, Lily Wang, Philip B. Paty, Paul B. Romesser, J. Joshua Smith, X. Steven Chen
Journal: Cancer Research
Cancer Res (2025) 85 (8_Supplement_1): 5026.
https://doi.org/10.1158/1538-7445.AM2025-5026
Published: 21 April 2025
View articletitled, Abstract 5026: Discovery of oncogenic mediator genes in rectal cancer chemotherapy response using gene expression data from matched tumor and patient-derived organoids
Journal Articles

Abstract A026: Identifying unique genomic and clinical characteristics of radiation-associated rectal cancer

Dana M. R. Omer, Anisha Luthra, Hannah M. Thompson, Jonathan B. Yuval, Paul B. Romesser, Philip B. Paty, Julio Garcia-Aguilar, Francisco Sanchez-Vega
Journal: Cancer Research
Cancer Res (2022) 82 (23_Supplement_1): A026.
https://doi.org/10.1158/1538-7445.CRC22-A026
Published: 01 December 2022
View articletitled, Abstract A026: Identifying unique genomic and clinical characteristics of radiation-associated rectal cancer
Journal Articles

Abstract 2394: Discovery of a sex-specific metabolic phenotype in KRAS mutant colorectal cancer

Hong Yan, Yuping Cai, Xinyi Shen, Abhishek Jain, Philip B Paty, Marcus Bosenberg, Sajid A Khan, Caroline Johnson
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2394.
https://doi.org/10.1158/1538-7445.AM2022-2394
Published: 15 June 2022
View articletitled, Abstract 2394: Discovery of a sex-specific metabolic phenotype in KRAS mutant colorectal cancer
Journal Articles

Colorectal Cancer Develops Inherent Radiosensitivity That Can Be Predicted Using Patient-Derived Organoids

Kuo-Shun Hsu, Mohammad Adileh, Maria Laura Martin, Vladimir Makarov, Jiapeng Chen, Chao Wu, Sahra Bodo, Stefan Klingler, Charles-Etienne Gabriel Sauvé, Bryan C. Szeglin, J. Joshua Smith, Zvi Fuks, Nadeem Riaz, Timothy A. Chan, Makoto Nishimura, Philip B. Paty, Richard Kolesnick
Journal: Cancer Research
Cancer Res (2022) 82 (12): 2298–2312.
https://doi.org/10.1158/0008-5472.CAN-21-4128
Published: 15 June 2022
View articletitled, Colorectal Cancer Develops Inherent Radiosensitivity That Can Be Predicted Using Patient-Derived Organoids
Open the PDF for Colorectal Cancer Develops Inherent Radiosensitivity That Can Be Predicted Using Patient-Derived Organoids in another window
Includes: Supplementary data
Journal Articles

Organoids Reveal That Inherent Radiosensitivity of Small and Large Intestinal Stem Cells Determines Organ Sensitivity

Maria Laura Martin, Mohammad Adileh, Kuo-Shun Hsu, Guoqiang Hua, Sang Gyu Lee, Christy Li, John D. Fuller, Jimmy A. Rotolo, Sahra Bodo, Stefan Klingler, Adriana Haimovitz-Friedman, Joseph O. Deasy, Zvi Fuks, Philip B. Paty, Richard N. Kolesnick
Journal: Cancer Research
Cancer Res (2020) 80 (5): 1219–1227.
https://doi.org/10.1158/0008-5472.CAN-19-0312
Published: 02 March 2020
View articletitled, Organoids Reveal That Inherent Radiosensitivity of Small and Large Intestinal Stem Cells Determines Organ Sensitivity
Open the PDF for Organoids Reveal That Inherent Radiosensitivity of Small and Large Intestinal Stem Cells Determines Organ Sensitivity in another window
Includes: Supplementary data
Journal Articles

Distinct Levels of Radioresistance in Lgr5+ Colonic Epithelial Stem Cells versus Lgr5+ Small Intestinal Stem Cells

Guoqiang Hua, Chu Wang, Yan Pan, Zhaoshi Zeng, Sang Gyu Lee, Maria Laura Martin, Adriana Haimovitz-Friedman, Zvi Fuks, Philip B. Paty, Richard Kolesnick
Journal: Cancer Research
Cancer Res (2017) 77 (8): 2124–2133.
https://doi.org/10.1158/0008-5472.CAN-15-2870
Published: 13 April 2017
View articletitled, Distinct Levels of Radioresistance in Lgr5+ Colonic Epithelial Stem Cells versus Lgr5+ Small Intestinal Stem Cells
Open the PDF for Distinct Levels of Radioresistance in Lgr5+ Colonic Epithelial Stem Cells versus Lgr5+ Small Intestinal Stem Cells in another window
Journal Articles

Abstract 3347: Radiation-induced gastrointestinal (GI) syndrome as a function of age

Hongyan Li, Herman Kucharavy, Carla Hajj, Guoqiang Hua, Ryan Glass, Zhaoshi Zeng, Zvi Fuks, Philip B. Paty, Richard Kolesnick, Karen Hubbard, Adriana Haimovitz-Friedman
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): 3347.
https://doi.org/10.1158/1538-7445.AM2015-3347
Published: 01 August 2015
View articletitled, Abstract 3347: Radiation-induced gastrointestinal (GI) syndrome as a function of age
Journal Articles

Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer

Manickam Janakiraman, Efsevia Vakiani, Zhaoshi Zeng, Christine A. Pratilas, Barry S. Taylor, Dhananjay Chitale, Ensar Halilovic, Manda Wilson, Kety Huberman, Julio Cezar Ricarte Filho, Yogindra Persaud, Douglas A. Levine, James A. Fagin, Suresh C. Jhanwar, John M. Mariadason, Alex Lash, Marc Ladanyi, Leonard B. Saltz, Adriana Heguy, Philip B. Paty, David B. Solit
Journal: Cancer Research
Cancer Res (2010) 70 (14): 5901–5911.
https://doi.org/10.1158/0008-5472.CAN-10-0192
Published: 14 July 2010
View articletitled, Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer
Open the PDF for Genomic and Biological Characterization of Exon 4 KRAS Mutations in Human Cancer in another window
Includes: Supplementary data
Journal Articles

γ-Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity

Raymond D. Meng, Christopher C. Shelton, Yue-Ming Li, Li-Xuan Qin, Daniel Notterman, Philip B. Paty, Gary K. Schwartz
Journal: Cancer Research
Cancer Res (2009) 69 (2): 573–582.
https://doi.org/10.1158/0008-5472.CAN-08-2088
Published: 15 January 2009
View articletitled, γ-Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity
Open the PDF for γ-Secretase Inhibitors Abrogate Oxaliplatin-Induced Activation of the Notch-1 Signaling Pathway in Colon Cancer Cells Resulting in Enhanced Chemosensitivity in another window
Includes: Supplementary data
Journal Articles

The Signatures of Autozygosity among Patients with Colorectal Cancer

Manny D. Bacolod, Gunter S. Schemmann, Shuang Wang, Richard Shattock, Sarah F. Giardina, Zhaoshi Zeng, Jinru Shia, Robert F. Stengel, Norman Gerry, Josephine Hoh, Tomas Kirchhoff, Bert Gold, Michael F. Christman, Kenneth Offit, William L. Gerald, Daniel A. Notterman, Jurg Ott, Philip B. Paty, Francis Barany
Journal: Cancer Research
Cancer Res (2008) 68 (8): 2610–2621.
https://doi.org/10.1158/0008-5472.CAN-07-5250
Published: 15 April 2008
View articletitled, The Signatures of Autozygosity among Patients with Colorectal Cancer
Open the PDF for The Signatures of Autozygosity among Patients with Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

Novel xenograft model to study MET/HGF-dependent tumor progression.

Todd D. Francone, Ron G. Landmann, Chin-Tung Chen, Eleanor Kuntz, Zhaoshi Zeng, Philip B. Paty, Martin R. Weiser
Journal: Cancer Research
Cancer Res (2006) 66 (8_Supplement): 1197.
Published: 15 April 2006
View articletitled, Novel xenograft model to study MET/HGF-dependent tumor progression.
Journal Articles

Relationship of Gene Expression and Chromosomal Abnormalities in Colorectal Cancer

Dafna Tsafrir, Manny Bacolod, Zachariah Selvanayagam, Ilan Tsafrir, Jinru Shia, Zhaoshi Zeng, Hao Liu, Curtis Krier, Robert F. Stengel, Francis Barany, William L. Gerald, Philip B. Paty, Eytan Domany, Daniel A. Notterman
Journal: Cancer Research
Cancer Res (2006) 66 (4): 2129–2137.
https://doi.org/10.1158/0008-5472.CAN-05-2569
Published: 17 February 2006
View articletitled, Relationship of Gene Expression and Chromosomal Abnormalities in Colorectal Cancer
Open the PDF for Relationship of Gene Expression and Chromosomal Abnormalities in Colorectal Cancer in another window
Includes: Supplementary data
Journal Articles

K-ras mutation and c-Met amplification are prognostic markers in resected liver metastases from colorectal cancer

Zhao-Shi Zeng, Garrett M. Nash, Martin R. Weiser, Mark Gimble, Mackevin Ndubuisi, Alfred T. Culliford, VII, Matthew D’Alessio, Yuka Yamaguchi, Francis Barany, Philip B. Paty
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 842.
Published: 01 May 2005
View articletitled, K-ras mutation and c-Met amplification are prognostic markers in resected liver metastases from colorectal cancer
Journal Articles

Comparative analysis of c-Met gene amplification in primary colorectal cancer and liver metastasis using PCR/LDR assay

Zhao-Shi Zeng, Garrett M. Nash, Mark Gimbel, Daniel R. Nathanson, Alfred T. Culliford, Matthew D’Alessio, Francis Barany, Philip B. Paty
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1170.
Published: 01 April 2004
View articletitled, Comparative analysis of c-Met gene amplification in primary colorectal cancer and liver metastasis using PCR/LDR assay