1-20 of 34
Philip A. Philip
Close
Save search
Follow your search
Access your saved searches in your account
Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles

Abstract CT080: A phase I study of CPI-613 (devimistat) in combination with chemoradiation in patients with pancreatic ductal adenocarcinoma

Mandana Kamgar, Husain Yar Khan, Amro Aboukameel, Sahar F. Bannoura, Brian Y. Chung, Aniko Szabo, Yiwei Li, Mohammed Najeeb Al Hallak, Philip A. Philip, Ben George, Kathleen K. Christians, Douglas B. Evans, Susan Tsai, Beth Erickson, John M. Goldberg, Asfar S. Azmi, William A. Hall
Journal: Cancer Research
Cancer Res (2024) 84 (7_Supplement): CT080.
https://doi.org/10.1158/1538-7445.AM2024-CT080
Published: 05 April 2024
View article titled, Abstract CT080: A phase I study of CPI-613 (devimistat) in combination with chemoradiation in patients with pancreatic ductal adenocarcinoma
Journal Articles

Abstract 5587: Regulator of chromosome condensation 1 (RCC1) as a novel therapeutic target in pancreatic ductal adenocarcinoma

Sahar F. Bannoura, Husain Y. Khan, Amro Aboukameel, Md Hafiz Uddin, Rund Nimri, Eliza Beal, Seongho Kim, Mohammed Najeeb Al Hallak, Bassel El-Rayes, Philip A. Philip, Boris Pasche, Ramzi Mohammad, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 5587.
https://doi.org/10.1158/1538-7445.AM2024-5587
Published: 22 March 2024
View article titled, Abstract 5587: Regulator of chromosome condensation 1 (RCC1) as a novel therapeutic target in pancreatic ductal adenocarcinoma
Journal Articles

Abstract 1939: NT219, a dual inhibitor of IRS1/2 and STAT3, suppresses cancer stem cell mediated resistance to KRASG12C and KRASG12D inhibitors in solid tumors

Hadas Reuveni, Mohammed Najeeb Al-Hallak, Sarah Motorwala, Eliza Beal, Steve Kim, Rafic Beydoun, Gergory Dyson, Bassel El-Rayes, Herbert Chen, Philip A. Philip, Anthony F. Shields, Boris Pasche, Katy Sigalov, Hava Ben-David, Daphna Miron, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 1939.
https://doi.org/10.1158/1538-7445.AM2024-1939
Published: 22 March 2024
View article titled, Abstract 1939: NT219, a dual inhibitor of IRS1/2 and STAT3, suppresses cancer stem cell mediated resistance to KRAS<sup>G12C</sup> and KRAS<sup>G12D</sup> inhibitors in solid tumors
Journal Articles

Abstract 4574: Next generation nuclear export blocker KPT8602 synergizes with KRASG12D inhibitor MRTX1133 resulting in improved antitumor effects against pancreatic ductal adenocarcinoma

Husain Yar Khan, Amro Aboukameel, Md Hafiz Uddin, Sahar F. Bannoura, Khaled Keffri, Medha Jasti, Rachael Virga, Sarah Motorwala, Khalil Choucair, Tarik Hadid, Mohammad Najeeb Al-Hallak, Eliza Beal, Miguel Tobon, Rafic Beydoun, Greg Dyson, Steve Kim, Misako Nagasaka, Philip A. Philip, Basel El-Rayes, Herbert Chen, Anthony Shields, Ramzi Mohammad, Boris Pasche, Asfar Azmi
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4574.
https://doi.org/10.1158/1538-7445.AM2024-4574
Published: 22 March 2024
View article titled, Abstract 4574: Next generation nuclear export blocker KPT8602 synergizes with KRAS<sup>G12D</sup> inhibitor MRTX1133 resulting in improved antitumor effects against pancreatic ductal adenocarcinoma
Journal Articles

Abstract B077: KRASG12D inhibitor MRTX1133 synergizes with the next generation nuclear transport protein inhibitor eltanexor resulting in enhanced antitumor activity against pancreatic ductal adenocarcinoma

Husain Y. Khan, Amro Aboukameel, Md Hafiz Uddin, Mohammad Najeeb Al-Hallak, Eliza W. Beal, Ibrahim Azar, Erkan Baloglu, Rafic Beydoun, Ammar Sukari, Misako Nagasaka, Amr Mohamed, Ahmed Kaseb, Philip A. Philip, Basel El-Rayes, Herbert Chen, Anthony Shields, Asfar Azmi
Journal: Cancer Research
Cancer Res (2024) 84 (2_Supplement): B077.
https://doi.org/10.1158/1538-7445.PANCA2023-B077
Published: 16 January 2024
View article titled, Abstract B077: KRAS<sup>G12D</sup> inhibitor MRTX1133 synergizes with the next generation nuclear transport protein inhibitor eltanexor resulting in enhanced antitumor activity against pancreatic ductal adenocarcinoma
Journal Articles

Abstract LB299: Identification of key regulators for nuclear protein export inhibitor and chemotherapy combination in pancreatic cancer using spatial genomics approach

Md. Hafiz Uddin, Sahar F. Bannoura, Husain Y. Khan, Amro Aboukameel, Yiwei Li, Ibrahim Azar, Eliza W. Bael, Miguel Tobon, Donald Weaver, Steve Kim, Tanya Odisho, Amr Mohammed, Gregory Dyson, Rafic Beydoun, Ramzi M. Mohammad, Herbert Chen, Bassel El-Rayes, Philip A. Philip, Mohammad N. Al-Hallak, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2023) 83 (8_Supplement): LB299.
https://doi.org/10.1158/1538-7445.AM2023-LB299
Published: 14 April 2023
View article titled, Abstract LB299: Identification of key regulators for nuclear protein export inhibitor and chemotherapy combination in pancreatic cancer using spatial genomics approach
Journal Articles

Abstract IA010: Meeting the challenge of pancreatic cancer

Philip A. Philip
Journal: Cancer Research
Cancer Res (2022) 82 (22_Supplement): IA010.
https://doi.org/10.1158/1538-7445.PANCA22-IA010
Published: 15 November 2022
View article titled, Abstract IA010: Meeting the challenge of pancreatic cancer
Journal Articles

Abstract 1231: Prognostic and predictive drug-induced gene signatures for colorectal cancer patients personalized based on p53 status and treatment with FOLFOX, 5-FU, oxaliplatin, or irinotecan

Lindsey Carlsen, Andrew Elliott, Marzia Capelletti, Micheal Hall, Philip A. Philip, Heinz-Josef Lenz, Howard Safran, Khaldoun Almhanna, Rimini Breakstone, Alexander G. Raufi, Emil Lou, John L. Marshall, W. Michael Korn, Wafik S. El-Deiry
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 1231.
https://doi.org/10.1158/1538-7445.AM2022-1231
Published: 15 June 2022
View article titled, Abstract 1231: Prognostic and predictive drug-induced gene signatures for colorectal cancer patients personalized based on p53 status and treatment with FOLFOX, 5-FU, oxaliplatin, or irinotecan
Journal Articles

Abstract CT234: PANOVA-3: A phase 3 study of tumor treating fields with gemcitabine and nab-paclitaxel for front-line treatment of locally advanced pancreatic adenocarcinoma

Vincent J. Picozzi, Judith Finlay, Teresa Macarulla, Philip A. Philip, Carlos R. Becerra, Tomislav Dragovich
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): CT234.
https://doi.org/10.1158/1538-7445.AM2022-CT234
Published: 15 June 2022
View article titled, Abstract CT234: PANOVA-3: A phase 3 study of tumor treating fields with gemcitabine and nab-paclitaxel for front-line treatment of locally advanced pancreatic adenocarcinoma
Journal Articles

Abstract 682: Associations of inflammatory biomarkers with survival among patients with stage III colon cancer (CALGB/SWOG 80702 [Alliance])

En Cheng, Shi Qian, Anthony F. Shields, Elizabeth M. Cespedes Feliciano, Andrew B. Nixon, Ardaman P. Shergill, Katherine A. Guthrie, Felix Couture, Philip Kuebler, Pankaj Kumar, Dequincy Lewis, Benjamin Tan, Eileen M. O'Reilly, Justin C. Brown, Philip A. Philip, Bette J. Caan, Jeffrey A. Meyerhardt
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 682.
https://doi.org/10.1158/1538-7445.AM2022-682
Published: 15 June 2022
View article titled, Abstract 682: Associations of inflammatory biomarkers with survival among patients with stage III colon cancer (CALGB/SWOG 80702 [Alliance])
Journal Articles

Abstract PO-051: PANOVA-3: A phase III study of tumor treating fields with nab-paclitaxel and gemcitabine for front-line treatment of locally advanced pancreatic adenocarcinoma

Vincent J. Picozzi, Teresa Macarulla, Philip A. Philip, Carlos R. Becerra, Tomislav Dragovich
Journal: Cancer Research
Cancer Res (2021) 81 (22_Supplement): PO-051.
https://doi.org/10.1158/1538-7445.PANCA21-PO-051
Published: 15 November 2021
View article titled, Abstract PO-051: PANOVA-3: A phase III study of tumor treating fields with nab-paclitaxel and gemcitabine for front-line treatment of locally advanced pancreatic adenocarcinoma
Journal Articles

Abstract 2383: Mir-7974: An oncogenic miRNA that perpetuates gastric cancer

Rachel E. Sexton, Mohammad Najeeb Al-Hallak, Bayan Al-Share, Yiwei Li, Amro Aboukameel, Yosef Landesman, Trinayan Kashyap, Steve Kim, Ramzi M. Mohammad, Philip A. Philip, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 2383.
https://doi.org/10.1158/1538-7445.AM2021-2383
Published: 01 July 2021
View article titled, Abstract 2383: Mir-7974: An oncogenic miRNA that perpetuates gastric cancer
Journal Articles

Abstract 1122: Novel targets for therapy resistant pancreatic neuroendocrine tumors

Gabriel B. Mpilla, Amro Aboukameel, Md Hafiz Uddin, Mohammed N. Al-Hallak, Bayan Al-Share, Yosef Landesman, Yiwei Li, Steve Kim, Rafic Beydoun, Ramzi M. Mohammad, Philip A. Philip, Bassel El-Rayes, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 1122.
https://doi.org/10.1158/1538-7445.AM2021-1122
Published: 01 July 2021
View article titled, Abstract 1122: Novel targets for therapy resistant pancreatic neuroendocrine tumors
Journal Articles

Abstract 234: A novel, small molecule inhibitor of dihydroorotate dehydrogenase (DHODH), RP7214, potentiates activity of chemotherapeutics in breast and colorectal cancers

Asfar S. Azmi, Amro Aboukameel, Mohammad Najeeb Al-Hallak, Philip A. Philip, Kumar Penmetsa, Srikant Visvanadha, Gabriel Mpilla, Rachel Sexton, Ramzi M. Mohammad
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 234.
https://doi.org/10.1158/1538-7445.AM2020-234
Published: 15 August 2020
View article titled, Abstract 234: A novel, small molecule inhibitor of dihydroorotate dehydrogenase (DHODH), RP7214, potentiates activity of chemotherapeutics in breast and colorectal cancers
Journal Articles

Abstract 3069: Efficacy of RP4010, a calcium release-activated calcium (CRAC) channel inhibitor, in preclinical models of gastrointestinal cancers

Irfana Muqbil, Rachel Sexton, Gabriel Mpilla, Anteneh Tesfaye, Steve Kim, Philip A. Philip, Amro Aboukameel, Srikant Viswanadah, Kumar V. Penmesta, Ramzi M. Mohammad, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3069.
https://doi.org/10.1158/1538-7445.AM2019-3069
Published: 01 July 2019
View article titled, Abstract 3069: Efficacy of RP4010, a calcium release-activated calcium (CRAC) channel inhibitor, in preclinical models of gastrointestinal cancers
Journal Articles

Abstract 3476: Evaluable antitumor activity in metastatic pancreatic adenocarcinoma with specific inhibitor of nuclear export based treatment

Asfar S. Azmi, Yosef Landesman, Michael Kauffman, Sharon Shacham, Gabriel Mpilla, Amro Aboukameel, Steve Kim, Mandana Kamgar, Anteneh Tesfaye, Ramzi M. Mohammad, Philip A. Philip
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3476.
https://doi.org/10.1158/1538-7445.AM2019-3476
Published: 01 July 2019
View article titled, Abstract 3476: Evaluable antitumor activity in metastatic pancreatic adenocarcinoma with specific inhibitor of nuclear export based treatment
Journal Articles

Abstract 4368: PAK4-NAMPT dual inhibition as a feasible strategy for treatment of resistant pancreatic neuroendocrine tumors

Gabriel Mpilla, Irfana Muqbil, Amro Aboukameel, Philip A. Philip, William Senapedis, Erkan Baloglu, Yosef Landesman, Michael Kauffman, Sharon Shacham, Ramzi M. Mohammad, Asfar S. Azmi
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 4368.
https://doi.org/10.1158/1538-7445.AM2018-4368
Published: 01 July 2018
View article titled, Abstract 4368: PAK4-NAMPT dual inhibition as a feasible strategy for treatment of resistant pancreatic neuroendocrine tumors
Journal Articles

Abstract 464: Novel role of xpo1 in regulating MicroRNAs related to pancreatic ductal adenocarcinoma invasion and metastasis

Asfar S. Azmi, Yiwei Li, Irfana Muqbil, Amro Aboukameel, William Senapedis, Erkan Baloglu, Yosef Landesman, Michael Kauffman, Sharon Shacham, Philip A. Philip, Ramzi M. Mohammad
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 464.
https://doi.org/10.1158/1538-7445.AM2017-464
Published: 01 July 2017
View article titled, Abstract 464: Novel role of xpo1 in regulating MicroRNAs related to pancreatic ductal adenocarcinoma invasion and metastasis
Journal Articles

Abstract B38: Clinical translation of nuclear export inhibitor in metastatic pancreatic cancer

Asfar S. Azmi, Irfana Muqbil, Amro Aboukameel, Michael Kauffman, Sharon Shacham, Ramzi M. Mohammad, Philip A. Philip
Journal: Cancer Research
Cancer Res (2016) 76 (24_Supplement): B38.
https://doi.org/10.1158/1538-7445.PANCA16-B38
Published: 14 December 2016
View article titled, Abstract B38: Clinical translation of nuclear export inhibitor in metastatic pancreatic cancer
Journal Articles

Abstract 1873: The role of p21-activated kinase 4 (PAK4) in cancer stemness and epithelial-to-mesenchymal transition

Asfar S. Azmi, Irfana Muqbil, Amro Aboukameel, William Senapedis, Erkan Baloglu, Yosef Landesman, Sharon Shacham, Michael Kauffman, Philip A. Philip, Ramzi M. Mohammad
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1873.
https://doi.org/10.1158/1538-7445.AM2016-1873
Published: 15 July 2016
View article titled, Abstract 1873: The role of p21-activated kinase 4 (PAK4) in cancer stemness and epithelial-to-mesenchymal transition