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Journal Articles

Abstract 2373: Analysis of the distinct activities of the C1a and C1b domains of protein kinase C theta

Agnes Czikora, Satyabrata Pany, Youngki You, Amandeep Saini, Noemi Kedei, Nancy E. Lewin, Adelle Abramovitz, Joydip Das, Peter M. Blumberg

Cancer Res (2017) 77 (13_Supplement): 2373.

https://doi.org/10.1158/1538-7445.AM2017-2373

Published: 01 July 2017

View article titled, Abstract 2373: Analysis of the distinct activities of the C1a and C1b domains of protein kinase C theta

Journal Articles

Abstract 215: Characterization by mass spectrometry of protein kinase C substrates differentially phosphorylated in LNCaP cells in response to phorbol ester and bryostatin 1 treatment

Noemi Kedei, Sudipto Das, Thorkell Andresson, Peter M. Blumberg

Cancer Res (2017) 77 (13_Supplement): 215.

https://doi.org/10.1158/1538-7445.AM2017-215

Published: 01 July 2017

View article titled, Abstract 215: Characterization by mass spectrometry of protein kinase C substrates differentially phosphorylated in LNCaP cells in response to phorbol ester and bryostatin 1 treatment

Journal Articles

Abstract 5344: Understanding the structural requirements of C1 domains for phorbol ester binding, analysis of the atypical C1 domain of STAC2

Adelle Abramovitz, Noemi Kedei, Peter M Blumberg

Cancer Res (2017) 77 (13_Supplement): 5344.

https://doi.org/10.1158/1538-7445.AM2017-5344

Published: 01 July 2017

View article titled, Abstract 5344: Understanding the structural requirements of C1 domains for phorbol ester binding, analysis of the atypical C1 domain of STAC2

Journal Articles

Abstract 3889: An aptamer-based multiplexed proteomic technology reveals differential PKC ligand responses

Jinqiu Chen, Noemi Kedei, David J. Goldstein, Mariam Q. Malik, Peter M. Blumberg

Cancer Res (2016) 76 (14_Supplement): 3889.

https://doi.org/10.1158/1538-7445.AM2016-3889

Published: 15 July 2016

View article titled, Abstract 3889: An aptamer-based multiplexed proteomic technology reveals differential PKC ligand responses

Journal Articles

Abstract 1126: Importance of the REM (Ras exchange) motif for membrane interactions by RasGRP3

Agnes Czikora, Noemi Kedei, Peter M. Blumberg

Cancer Res (2016) 76 (14_Supplement): 1126.

https://doi.org/10.1158/1538-7445.AM2016-1126

Published: 15 July 2016

View article titled, Abstract 1126: Importance of the REM (Ras exchange) motif for membrane interactions by RasGRP3

Journal Articles

Abstract 4423: Methylation and acetylation are novel post-translational modifications identified for the pre-apoptotic protein kinase C (PKC) delta

Noemi Kedei, Elliott L. Paine, Lisa M. Miller Jenkins, Peter M. Blumberg

Cancer Res (2016) 76 (14_Supplement): 4423.

https://doi.org/10.1158/1538-7445.AM2016-4423

Published: 15 July 2016

View article titled, Abstract 4423: Methylation and acetylation are novel post-translational modifications identified for the pre-apoptotic protein kinase C (PKC) delta

Journal Articles

Abstract 4977: Dramatic differences in the extents and patterns of PKC delta modification among the different members of the NCI-60 cancer cell line panel

Noemi Kedei, Jin-Qiu Chen, Michelle Herrmann, Tiffany Hu, Karina Chang, Peter M. Blumberg

Cancer Res (2015) 75 (15_Supplement): 4977.

https://doi.org/10.1158/1538-7445.AM2015-4977

Published: 01 August 2015

View article titled, Abstract 4977: Dramatic differences in the extents and patterns of PKC delta modification among the different members of the NCI-60 cancer cell line panel

Journal Articles

Abstract 3928: Structural basis for the failure of the C1 domain of RasGRP2 to bind phorbol ester

Agnes Czikora, Daniel J. Lundberg, Nancy E. Lewin, Noemi Kedei, Peter M. Blumberg

Cancer Res (2015) 75 (15_Supplement): 3928.

https://doi.org/10.1158/1538-7445.AM2015-3928

Published: 01 August 2015

View article titled, Abstract 3928: Structural basis for the failure of the C1 domain of RasGRP2 to bind phorbol ester

Journal Articles

Abstract 3195: Transient duration of action is the primary mechanism responsible for the unique biology of bryostatin 1

Noemi Kedei, Aleksandra M. Michalowski, Peter M. Blumberg

Cancer Res (2014) 74 (19_Supplement): 3195.

https://doi.org/10.1158/1538-7445.AM2014-3195

Published: 01 October 2014

View article titled, Abstract 3195: Transient duration of action is the primary mechanism responsible for the unique biology of bryostatin 1

Journal Articles

Abstract 5315: Quantitative proteomic assessment of differential ligand responses downstream of protein kinase C activation

Jin-Qiu Chen, Noemi Kedei, Michelle A. Herrmann, Peter M. Blumberg

Cancer Res (2014) 74 (19_Supplement): 5315.

https://doi.org/10.1158/1538-7445.AM2014-5315

Published: 01 October 2014

View article titled, Abstract 5315: Quantitative proteomic assessment of differential ligand responses downstream of protein kinase C activation

Journal Articles

Abstract 4450: Comparison of structural elements in RasGRP3 and RasGRP1 controlling membrane interaction

Agnes Czikora, Noemi Kedei, Peter M. Blumberg

Cancer Res (2014) 74 (19_Supplement): 4450.

https://doi.org/10.1158/1538-7445.AM2014-4450

Published: 01 October 2014

View article titled, Abstract 4450: Comparison of structural elements in RasGRP3 and RasGRP1 controlling membrane interaction

Journal Articles

Abstract 4399: Investigation of RasGRP3 expression and function in human breast cancers and breast-derived ductal adenocarcinoma cell lines.

Zsuzsanna Nagy, Edina Orosz, Ilona Kovács, Miklós Török, DezsŹ Tóth, Tamás Bíró, Peter M. Blumberg, Gabriella Czifra

Cancer Res (2013) 73 (8_Supplement): 4399.

https://doi.org/10.1158/1538-7445.AM2013-4399

Published: 15 April 2013

View article titled, Abstract 4399: Investigation of RasGRP3 expression and function in human breast cancers and breast-derived ductal adenocarcinoma cell lines.

Journal Articles

Abstract 2101: Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogue in LNCaP and U937 cells provides insight into their differential mechanism.

Noemi Kedei, Aleksandra M. Michalowski, Mark E. Petersen, Gary E. Keck, Peter M. Blumberg

Cancer Res (2013) 73 (8_Supplement): 2101.

https://doi.org/10.1158/1538-7445.AM2013-2101

Published: 15 April 2013

View article titled, Abstract 2101: Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogue in LNCaP and U937 cells provides insight into their differential mechanism.

Journal Articles

Abstract 3815: Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogues in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action

Noemi Kedei, Andrea Telek, Aleksandra M. Michalowski, Matthew B. Kraft, Wei Li, Yam B. Poudel, Arnab Rudra, Mark E. Petersen, Gary E. Keck, Peter M. Blumberg

Cancer Res (2012) 72 (8_Supplement): 3815.

https://doi.org/10.1158/1538-7445.AM2012-3815

Published: 15 April 2012

View article titled, Abstract 3815: Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogues in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action

Journal Articles

Abstract 4058: Diverse patterns of biological response to phorbol esters and related protein kinaseC activators in LNCaP human prostate cancer cells

Noemi Kedei, Andrea Telek, Emanuel S. Lubart, Nancy E. Lewin, Dazhi Yang, Jinqiu Chen, Michelle A. Herrmann, Paul K. Goldsmith, Langston Lim, Poonam Mannam, Susan H. Garfield, Peter M. Blumberg

Cancer Res (2011) 71 (8_Supplement): 4058.

https://doi.org/10.1158/1538-7445.AM2011-4058

Published: 15 April 2011

View article titled, Abstract 4058: Diverse patterns of biological response to phorbol esters and related protein kinaseC activators in LNCaP human prostate cancer cells

Journal Articles

Abstract 3854: Identification of crucial residues at the rim of the binding cleft of the C1 domain of Vav1 that determine its ligand sensitivity

Tamas Geczy, Christopher J. Valle, Julia S. Selezneva, Noemi Kedei, Nancy E. Lewin, Langston Lim, Poonam Mannam, Susan H. Garfield, Megan L. Peach, Peter M. Blumberg

Cancer Res (2011) 71 (8_Supplement): 3854.

https://doi.org/10.1158/1538-7445.AM2011-3854

Published: 15 April 2011

View article titled, Abstract 3854: Identification of crucial residues at the rim of the binding cleft of the C1 domain of Vav1 that determine its ligand sensitivity

Journal Articles

RasGRP3 Contributes to Formation and Maintenance of the Prostate Cancer Phenotype

Dazhi Yang, Noemi Kedei, Luowei Li, Juan Tao, Julia F. Velasquez, Aleksandra M. Michalowski, Balázs I. Tóth, Rita Marincsák, Attila Varga, Tamás Bíró, Stuart H. Yuspa, Peter M. Blumberg

Cancer Res (2010) 70 (20): 7905–7917.

https://doi.org/10.1158/0008-5472.CAN-09-4729

Published: 13 October 2010

View article titled, RasGRP3 Contributes to Formation and Maintenance of the Prostate Cancer Phenotype

Includes: Supplementary data

Journal Articles

Abstract 4500: What distinguishes a PKC activator like phorbol ester from a PKC functional antagonist like bryostatin 1? Bryologues permit mechanistic insight

Noemi Kedei, Andrea Telek, Gabriella Czifra, Alexandra Czap, Jinqiu Chen, Paul K. Goldsmith, Gary E. Keck, Peter M. Blumberg

Cancer Res (2010) 70 (8_Supplement): 4500.

https://doi.org/10.1158/1538-7445.AM10-4500

Published: 15 April 2010

View article titled, Abstract 4500: What distinguishes a PKC activator like phorbol ester from a PKC functional antagonist like bryostatin 1? Bryologues permit mechanistic insight

Journal Articles

Differential Effect of Bryostatin 1 and Phorbol 12-Myristate 13-Acetate on HOP-92 Cell Proliferation Is Mediated by Down-regulation of Protein Kinase Cδ

Sung Hee Choi, Tehila Hyman, Peter M. Blumberg

Cancer Res (2006) 66 (14): 7261–7269.

https://doi.org/10.1158/0008-5472.CAN-05-4177

Published: 18 July 2006

View article titled, Differential Effect of Bryostatin 1 and Phorbol 12-Myristate 13-Acetate on HOP-92 Cell Proliferation Is Mediated by Down-regulation of Protein Kinase Cδ

Journal Articles

The differential effects of bryostatin 1 and phorbol 12-myristate 13-acetate on HOP-92 cells: Bryostatin 1 induced biphasic cell progression is mediated by down regulation of PKC delta

Sunghee Choi, Hyman Tehila, Peter M. Blumberg

Cancer Res (2006) 66 (8_Supplement): 453.

Published: 15 April 2006

View article titled, The differential effects of bryostatin 1 and phorbol 12-myristate 13-acetate on HOP-92 cells: Bryostatin 1 induced biphasic cell progression is mediated by down regulation of PKC delta

NARROW

Abstract 2373: Analysis of the distinct activities of the C1a and C1b domains of protein kinase C theta

Abstract 215: Characterization by mass spectrometry of protein kinase C substrates differentially phosphorylated in LNCaP cells in response to phorbol ester and bryostatin 1 treatment

Abstract 5344: Understanding the structural requirements of C1 domains for phorbol ester binding, analysis of the atypical C1 domain of STAC2

Abstract 3889: An aptamer-based multiplexed proteomic technology reveals differential PKC ligand responses

Abstract 1126: Importance of the REM (Ras exchange) motif for membrane interactions by RasGRP3

Abstract 4423: Methylation and acetylation are novel post-translational modifications identified for the pre-apoptotic protein kinase C (PKC) delta

Abstract 4977: Dramatic differences in the extents and patterns of PKC delta modification among the different members of the NCI-60 cancer cell line panel

Abstract 3928: Structural basis for the failure of the C1 domain of RasGRP2 to bind phorbol ester

Abstract 3195: Transient duration of action is the primary mechanism responsible for the unique biology of bryostatin 1

Abstract 5315: Quantitative proteomic assessment of differential ligand responses downstream of protein kinase C activation

Abstract 4450: Comparison of structural elements in RasGRP3 and RasGRP1 controlling membrane interaction

Abstract 4399: Investigation of RasGRP3 expression and function in human breast cancers and breast-derived ductal adenocarcinoma cell lines.

Abstract 2101: Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogue in LNCaP and U937 cells provides insight into their differential mechanism.

Abstract 3815: Comparison of transcriptional response to phorbol ester, bryostatin 1, and bryostatin analogues in LNCaP and U937 cancer cell lines provides insight into their differential mechanism of action

Abstract 4058: Diverse patterns of biological response to phorbol esters and related protein kinaseC activators in LNCaP human prostate cancer cells

Abstract 3854: Identification of crucial residues at the rim of the binding cleft of the C1 domain of Vav1 that determine its ligand sensitivity

RasGRP3 Contributes to Formation and Maintenance of the Prostate Cancer Phenotype

Abstract 4500: What distinguishes a PKC activator like phorbol ester from a PKC functional antagonist like bryostatin 1? Bryologues permit mechanistic insight

Differential Effect of Bryostatin 1 and Phorbol 12-Myristate 13-Acetate on HOP-92 Cell Proliferation Is Mediated by Down-regulation of Protein Kinase Cδ

The differential effects of bryostatin 1 and phorbol 12-myristate 13-acetate on HOP-92 cells: Bryostatin 1 induced biphasic cell progression is mediated by down regulation of PKC delta

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