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Peter Lichter
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Journal Articles

Abstract PO3-15-05: B cell immunology predict response and survival in PD-1/PD-L1 targeting immune checkpoint inhibition of metastatic breast cancer

Carlo Fremd, Markus Schulze, Miray Cetin, Hannah Boehm, Bénédicte Lenoire, Oezlem Akilli-Oeztuerk, Inka Zörnig, Pornpimol Charoentong, Yanhong Lyu, Catch Collaborators, Daniel Hübschmann, Felix Kommoss, Verena Thewes, Andreas Schneeweiss, Marc Zapatka, Felix Hartmann, Peter Lichter
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO3-15-05.
https://doi.org/10.1158/1538-7445.SABCS23-PO3-15-05
Published: 02 May 2024
View article titled, Abstract PO3-15-05: B cell immunology predict response and survival in PD-1/PD-L1 targeting immune checkpoint inhibition of metastatic breast cancer
Journal Articles

Abstract PO1-19-05: COGNITION/-GUIDE – Implementation of Precision Oncology in Early High-Risk Breast Cancer

Verena Thewes, Luise Strassl, Marc Zapatka, Mario Hlevnjak, Constantin Pixberg, Christian Maurer, Katharina Smetanay, Carlo Fremd, Laura Michel, Sabine Heublein, Celina V. Wagner, Jan-Philip Suppelna, Lars Buschhorn, Albrecht Stenzinger, Renate Haidinger, Eva Schumacher-Wulf, Sibylle Loibl, Pauline Wimberger, Jens-Uwe Blohmer, Peter A. Fasching, Wolfgang Janni, Richard F. Schlenk, Peter Lichter, Andreas Schneeweiss
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PO1-19-05.
https://doi.org/10.1158/1538-7445.SABCS23-PO1-19-05
Published: 02 May 2024
View article titled, Abstract PO1-19-05: COGNITION/-GUIDE – Implementation of Precision Oncology in Early High-Risk Breast Cancer
Journal Articles

Abstract 4886: An in-depth single-cell map of inflammatory breast cancer reveals wide-scaled restructuring associated to an immunosuppressive and inflammation-like microenvironment

Paul Schwerd-Kleine, Tasneem Cheytan, Roberto Würth, Ewgenija Gutjahr, Laura Michel, Verena Thewes, Peter Lichter, Andreas Schneeweiss, Andreas Trumpp, Martin Sprick
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 4886.
https://doi.org/10.1158/1538-7445.AM2024-4886
Published: 22 March 2024
View article titled, Abstract 4886: An in-depth single-cell map of inflammatory breast cancer reveals wide-scaled restructuring associated to an immunosuppressive and inflammation-like microenvironment
Journal Articles

Chromothripsis in Human Breast Cancer

Michiel Bolkestein, John K.L. Wong, Verena Thewes, Verena Körber, Mario Hlevnjak, Shaymaa Elgaafary, Markus Schulze, Felix K.F. Kommoss, Hans-Peter Sinn, Tobias Anzeneder, Steffen Hirsch, Frauke Devens, Petra Schröter, Thomas Höfer, Andreas Schneeweiss, Peter Lichter, Marc Zapatka, Aurélie Ernst
Journal: Cancer Research
Cancer Res (2020) 80 (22): 4918–4931.
https://doi.org/10.1158/0008-5472.CAN-20-1920
Published: 13 November 2020
View article titled, Chromothripsis in Human Breast Cancer
Open the PDF for Chromothripsis in Human Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract PD2-01: Exploring CDK4/6 inhibitor therapy response and drug resistance development at the single cell level in metastatic breast cancer CTCs

Andreas Trumpp, Lisa Becker, Michael Fletcher, Roberto Würth, Anand Thippeswamy, Simon Haas, Lars Velten, Laura Michel, Frederik Marme, Sarah Jauch, Mirjam Becker, Lars Steinmetz, Andreas Schneeweiss, Marc Zapatka, Peter Lichter, Martin Sprick
Journal: Cancer Research
Cancer Res (2020) 80 (4_Supplement): PD2-01.
https://doi.org/10.1158/1538-7445.SABCS19-PD2-01
Published: 15 February 2020
View article titled, Abstract PD2-01: Exploring CDK4/6 inhibitor therapy response and drug resistance development at the single cell level in metastatic breast cancer CTCs
Journal Articles

Abstract 3496: Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors

Manasi Ratnaparkhe, John K. Wong, Pei-Chi Wei, Mario Hlevnjak, Thorsten Kolb, Milena Simovic, Daniel Haag, Yashna Paul, Frauke Devens, Paul Northcott, David T. Jones, Marcel Kool, Anna Jauch, Agata Pastorczak, Wojciech Mlynarski, Andrey Korshunov, Rajiv Kumar, Susanna M. Downing, Stefan M. Pfister, Marc Zapatka, Peter J. McKinnon, Frederick W. Alt, Peter Lichter, Aurelie Ernst
Journal: Cancer Research
Cancer Res (2019) 79 (13_Supplement): 3496.
https://doi.org/10.1158/1538-7445.AM2019-3496
Published: 01 July 2019
View article titled, Abstract 3496: Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors
Journal Articles

Abstract IA11: Pediatric precision oncology programs in Germany and Europe

David T. W. Jones, Barbara C. Worst, Elke Pfaff, Cornelis M. Van Tilburg, Gnana Prakash Balasubramanian, Petra Fiesel, Kristian W. Pajtler, Angelika Freitag, Ruth Witt, Andreas E. Kulozik, Felix Sahm, Andreas von Deimling, Angelika Eggert, Uta Dirksen, Peter Lichter, David Capper, Olaf Witt, Stefan M. Pfister
Journal: Cancer Research
Cancer Res (2018) 78 (19_Supplement): IA11.
https://doi.org/10.1158/1538-7445.PEDCA17-IA11
Published: 01 October 2018
View article titled, Abstract IA11: Pediatric precision oncology programs in Germany and Europe
Journal Articles

Abstract 1906: PFKFB4, much more than just a glycolytic gene

Emma L. Phillips, Frederic Bethke, Jörg Balss, Stefan Pusch, Stefan Christen, Martina Schnölzer, Antje Habel, David Capper, Andreas Von Deimling, Sarah-Maria Fendt, Peter Lichter, Violaine Goidts
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1906.
https://doi.org/10.1158/1538-7445.AM2018-1906
Published: 01 July 2018
View article titled, Abstract 1906: <em>PFKFB4</em>, much more than just a glycolytic gene
Journal Articles

Abstract 1352: Inactivation of factors of DNA double-strand break repair by homologous recombination or non-homologous end-joining leads to frequent catastrophic genomic events in murine and human tumors

Manasi Ratnaparkhe, John Wong, Pei-Chi Wei, Mario Hlevnjak, Paul Northcott, David T. Jones, Marcel Kool, Anna Jauch, Agata Pastorczak, Andrey Korshunov, Rajiv Kumar, Susanna M. Downing, Stefan M. Pfister, Marc Zapatka, Peter J. McKinnon, Frederick W. Alt, Peter Lichter, Aurelie Ernst
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1352.
https://doi.org/10.1158/1538-7445.AM2018-1352
Published: 01 July 2018
View article titled, Abstract 1352: Inactivation of factors of DNA double-strand break repair by homologous recombination or non-homologous end-joining leads to frequent catastrophic genomic events in murine and human tumors
Journal Articles

Abstract 5109: Somatic CRISPR/Cas9-mediated gene editing enables versatile brain tumor modeling

Marc Zuckermann, Britta Ismer, Volker Hovestadt, Christiane B. Knobbe-Thomsen, Marc Zapatka, Paul A. Northcott, Martine F. Roussel, Guido Reifenberger, Peter Lichter, Stefan M. Pfister, Daisuke Kawauchi, Jan Gronych, David T. Jones
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 5109.
https://doi.org/10.1158/1538-7445.AM2018-5109
Published: 01 July 2018
View article titled, Abstract 5109: Somatic CRISPR/Cas9-mediated gene editing enables versatile brain tumor modeling
Journal Articles

Abstract 509: Genomic profiling of acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between ATM mutations and chromothripsis

Manasi Ratnaparkhe, Mario Hlevnjak, Thorsten Kolb, Anna Jauch, Kendra Maass, Frauke Devens, Agata Rode, Volker Hovestadt, Andrey Korshunov, Agata Pastorczak, Wojciech Mlynarski, Stephanie Sungalee, Jan Korbel, Jessica Hoell, Ute Fischer, Till Milde, Christof Kramm, Michaela Nathrath, Krystyna Chrzanowska, Eugen Tausch, Masatoshi Takagi, Takashi Taga, Shlomi Constantini, Jan Loeffen, Jules Meijerink, Stefan Zielen, Gudrun Goehring, Brigitte Schlegelberger, Eberhard Maass, Reiner Siebert, Joachim Kunz, Andreas Kulozik, Barbara Worst, David Jones, Stefan Pfister, Marc Zapatka, Peter Lichter, Aurelie Ernst
Journal: Cancer Research
Cancer Res (2017) 77 (13_Supplement): 509.
https://doi.org/10.1158/1538-7445.AM2017-509
Published: 01 July 2017
View article titled, Abstract 509: Genomic profiling of acute lymphoblastic leukemia in ataxia telangiectasia patients reveals tight link between <em>ATM</em> mutations and chromothripsis
Journal Articles

Abstract A30: Chronic lymphocytic leukemia-derived extracellular vesicles mediate NFkB signaling and pro-inflammatory cytokine release in monocytes

Franziska Haderk, Laura Llao Cid, Etienne Moussay, Jerome Paggetti, Karolin Willmund, Jana Seiler, Sven Diederichs, Maria Goebel, Jan Duerig, Thorsten Zenz, Stephan Stilgenbauer, Marc Zapatka, Peter Lichter, Martina Seiffert
Journal: Cancer Research
Cancer Res (2016) 76 (15_Supplement): A30.
https://doi.org/10.1158/1538-7445.TME16-A30
Published: 28 July 2016
View article titled, Abstract A30: Chronic lymphocytic leukemia-derived extracellular vesicles mediate NFkB signaling and pro-inflammatory cytokine release in monocytes
Journal Articles

Abstract 2696: Four new brain tumor entities emerge from molecular classification of CNS-PNETs

Dominik Sturm, Brent Orr, Umut H. Toprak, Volker Hovestadt, David T.W. Jones, David Capper, Peter Lichter, Andrey Korshunov, Stefan M. Pfister, David W. Ellison, Marcel Kool
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 2696.
https://doi.org/10.1158/1538-7445.AM2016-2696
Published: 15 July 2016
View article titled, Abstract 2696: Four new brain tumor entities emerge from molecular classification of CNS-PNETs
Journal Articles

Abstract PR02: Somatic CRISPR/Cas9-mediated tumor suppressor disruption enables versatile brain tumor modeling

Marc Zuckermann, Volker Hovestadt, Christiane B. Knobbe-Thomsen, Marc Zapatka, Paul A. Northcott, Kathrin Schramm, Jelena Belic, David T.W. Jones, Barbara Tschida, Branden Moriarity, David Largaespada, Martine F. Roussel, Andrey Korshunov, Guido Reifenberger, Stefan M. Pfister, Peter Lichter, Daisuke Kawauchi, Jan Gronych
Journal: Cancer Research
Cancer Res (2015) 75 (23_Supplement): PR02.
https://doi.org/10.1158/1538-7445.BRAIN15-PR02
Published: 09 December 2015
View article titled, Abstract PR02: Somatic CRISPR/Cas9-mediated tumor suppressor disruption enables versatile brain tumor modeling
Journal Articles

Abstract LB-114: The INFORM personalized medicine study for high-risk pediatric cancer patients

Barbara C. Worst, Cornelis M. van Tilburg, Gnana P. Balasubramanian, Petra Fiesel, David Capper, Miream Boudalil, Stephan Wolf, Sabine Schmidt, Melanie Bewerunge-Hudler, Matthias Schick, Angelika Freitag, Ruth Witt, Lenka Taylor, Andreas von Deimling, Matthias Schlesner, Angelika Eggert, Peter Lichter, David TW Jones, Olaf Witt, Stefan M. Pfister
Journal: Cancer Research
Cancer Res (2015) 75 (15_Supplement): LB-114.
https://doi.org/10.1158/1538-7445.AM2015-LB-114
Published: 01 August 2015
View article titled, Abstract LB-114: The INFORM personalized medicine study for high-risk pediatric cancer patients
Journal Articles

Reprogramming of the ERRα and ERα Target Gene Landscape Triggers Tamoxifen Resistance in Breast Cancer

Verena Thewes, Ronald Simon, Petra Schroeter, Magdalena Schlotter, Tobias Anzeneder, Reinhard Büttner, Vladimir Benes, Guido Sauter, Barbara Burwinkel, Robert I. Nicholson, Hans-Peter Sinn, Andreas Schneeweiss, Ulrich Deuschle, Marc Zapatka, Stefanie Heck, Peter Lichter
Journal: Cancer Research
Cancer Res (2015) 75 (4): 720–731.
https://doi.org/10.1158/0008-5472.CAN-14-0652
Published: 15 February 2015
View article titled, Reprogramming of the ERRα and ERα Target Gene Landscape Triggers Tamoxifen Resistance in Breast Cancer
Open the PDF for Reprogramming of the ERRα and ERα Target Gene Landscape Triggers Tamoxifen Resistance in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups

Hendrik Witt, Martin Sill, Khalida Wani, Steve Mack, David Capper, Stephanie Heim, Pascal Johann, Sally Lambert, Marina Rhyzova, Volker Hovestadt, Theophilos Tzaridis, Kristian Pajtler, Sebastian Bender, Till Milde, Paul A. Northcott, Andreas E. Kulozik, Olaf Witt, Peter Lichter, V Peter Collins, Andreas von Deimling, Marcel Kool, Michael D. Taylor, Martin Hasselblatt, David T. Jones, Andrey Korshunov, Ken Aldape, Stefan Pfister
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3094.
https://doi.org/10.1158/1538-7445.AM2014-3094
Published: 01 October 2014
View article titled, Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups
Journal Articles

Abstract 3093: Unravelling the biology of aggressive and therapy-resistant embryonal tumors with multilayered rosettes (ETMR)

Marcel Kool, Natalie Jäger, Dominik Sturm, David T.W. Jones, Volker Hoverstadt, Ivo Buchhalter, Pascal Johann, Christin Schmidt, Marina Ryzhova, Paul A. Northcott, Pablo Landgraf, Marc Remke, Michael D. Taylor, Martin Hasselblatt, Ulrich Schüller, Annie Huang, Marie-Laure Yaspo, Andreas von Deimling, Roland Eils, Peter Lichter, Andrey Korshunov, Stefan M. Pfister
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3093.
https://doi.org/10.1158/1538-7445.AM2014-3093
Published: 01 October 2014
View article titled, Abstract 3093: Unravelling the biology of aggressive and therapy-resistant embryonal tumors with multilayered rosettes (ETMR)
Journal Articles

Abstract 3084: Epigenetic deregulation in H3.3-K27M mutant pediatric high-grade gliomas

Sebastian Bender, Yujie Tang, Anders M. Lindroth, Volker Hovestadt, Marc Zapatka, David T.W. Jones, Marcel Kool, Paul A. Northcott, Dominik Sturm, Peter Lichter, Christoph Plass, Yoon-Jae Cho
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): 3084.
https://doi.org/10.1158/1538-7445.AM2014-3084
Published: 01 October 2014
View article titled, Abstract 3084: Epigenetic deregulation in H3.3-K27M mutant pediatric high-grade gliomas
Journal Articles

Abstract LB-203: Structural variants shuffle chromatin to activate GFI1 family oncogenes in medulloblastoma

Catherine Lee, Paul A. Northcott, Thomas Zichner, Peter Lichter, Jan O. Korbel, Stefan M. Pfister, Robert J. Wechsler-Reya
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-203.
https://doi.org/10.1158/1538-7445.AM2014-LB-203
Published: 01 October 2014
View article titled, Abstract LB-203: Structural variants shuffle chromatin to activate GFI1 family oncogenes in medulloblastoma