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Journal Articles

Abstract C011: The impact of reproductive factors on breast tumor and normal-adjacent tissue immune profile from menarche to menopause

Cheng Peng, Yuxi Liu, Yujing Heng, Clara Bodelon, Daniel Stover, Wendy Y. Chen, Michelle D. Holmes, A. Heather Eliassen, Peter Kraft, Rulla M. Tamimi
Journal: Cancer Research
Cancer Res (2024) 84 (22_Supplement): C011.
https://doi.org/10.1158/1538-7445.TUMBODY-C011
Published: 17 November 2024
View article titled, Abstract C011: The impact of reproductive factors on breast tumor and normal-adjacent tissue immune profile from menarche to menopause
Journal Articles

Abstract PS10-09: Development of an absolute risk prediction model for premenopausal breast cancer in an international consortium

Kristen Brantley, Michael Jones, Minouk Schoemaker, Hazel Nichols, Anthony Swerdlow, Robert MacInnis, Roger Milne, Tess Clenenden, Yu Chen, Xiao-Ou Shu, Wei Zheng, Woon-Puay Koh, Jian-Min Yuan, Cari Kitahara, Martha Linet, Dale Sandler, Bernard A Rosner, Peter Kraft, A. Heather Eliassen
Journal: Cancer Research
Cancer Res (2024) 84 (9_Supplement): PS10-09.
https://doi.org/10.1158/1538-7445.SABCS23-PS10-09
Published: 02 May 2024
View article titled, Abstract PS10-09: Development of an absolute risk prediction model for premenopausal breast cancer in an international consortium
Journal Articles

Abstract 6155: Germline variants in cancer susceptibility genes and subsequent neoplasm risks after childhood cancer: A pooled analysis of two large-scale cohorts

Shahriar A. Zamani, Danielle M. Karyadi, Stephen W. Hartley, Joshua N. Sampson, Todd Gibson, Peter Kraft, Stephen J. Chanock, Lindsay M. Morton
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6155.
https://doi.org/10.1158/1538-7445.AM2024-6155
Published: 22 March 2024
View article titled, Abstract 6155: Germline variants in cancer susceptibility genes and subsequent neoplasm risks after childhood cancer: A pooled analysis of two large-scale cohorts
Journal Articles

Abstract 6141: Genetic risk, health-associated lifestyle, and risk of early-onset total cancer and breast cancer: A prospective cohort study

Yin Zhang, Yuxi Liu, Kathryn L. Penney, Sara Lindström, Peter Kraft
Journal: Cancer Research
Cancer Res (2024) 84 (6_Supplement): 6141.
https://doi.org/10.1158/1538-7445.AM2024-6141
Published: 22 March 2024
View article titled, Abstract 6141: Genetic risk, health-associated lifestyle, and risk of early-onset total cancer and breast cancer: A prospective cohort study
Journal Articles

Abstract B051: Genome-wide association studies of 26,187 women without ovarian cancer identifies 12 genetic loci of blood CA125

Naoko Sasamoto, Jihye Kim, Constance Turman, Shelley S. Tworoger, Rudolf Kaaks, Renée T. Fortner, Daniel W. Cramer, Kathryn L. Terry, Nicolas Wentzensen, Peter Kraft
Journal: Cancer Research
Cancer Res (2024) 84 (5_Supplement_2): B051.
https://doi.org/10.1158/1538-7445.OVARIAN23-B051
Published: 04 March 2024
View article titled, Abstract B051: Genome-wide association studies of 26,187 women without ovarian cancer identifies 12 genetic loci of blood CA125
Journal Articles

Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C

Chunling Hu, Anil Belur Nagaraj, Hermela Shimelis, Gemma Montalban, Kun Y. Lee, Huaizhi Huang, Carolyn A. Lumby, Jie Na, Lisa R. Susswein, Maegan E. Roberts, Megan L. Marshall, Susan Hiraki, Holly LaDuca, Elizabeth Chao, Amal Yussuf, Tina Pesaran, Susan L. Neuhausen, Christopher A. Haiman, Peter Kraft, Sara Lindstrom, Julie R. Palmer, Lauren R. Teras, Celine M. Vachon, Song Yao, Irene Ong, Katherine L. Nathanson, Jeffrey N. Weitzel, Nicholas Boddicker, Rohan Gnanaolivu, Eric C. Polley, Georges Mer, Gaofeng Cui, Rachid Karam, Marcy E. Richardson, Susan M. Domchek, Siddhartha Yadav, Kathleen S. Hruska, Jill Dolinsky, S. John Weroha, Steven N. Hart, Jacques Simard, Jean Yves Masson, Yuan-Ping Pang, Fergus J. Couch
Journal: Cancer Research
Cancer Res (2023) 83 (15): 2557–2571.
https://doi.org/10.1158/0008-5472.CAN-22-2319
Published: 01 August 2023
View article titled, Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C
Open the PDF for Functional and Clinical Characterization of Variants of Uncertain Significance Identifies a Hotspot for Inactivating Missense Variants in RAD51C in another window
Includes: Supplementary data
Journal Articles

Germline Cancer Gene Expression Quantitative Trait Loci Are Associated with Local and Global Tumor Mutations

Yuxi Liu, Alexander Gusev, Peter Kraft
Journal: Cancer Research
Cancer Res (2023) 83 (8): 1191–1202.
https://doi.org/10.1158/0008-5472.CAN-22-2624
Published: 14 April 2023
View article titled, Germline Cancer Gene Expression Quantitative Trait Loci Are Associated with Local and Global Tumor Mutations
Open the PDF for Germline Cancer Gene Expression Quantitative Trait Loci Are Associated with Local and Global Tumor Mutations in another window
Includes: Supplementary data
Journal Articles

Abstract 1183: Mutation type and location in breast cancer susceptibility genes are associated with differential risk in the general population

Mwangala P. Akamandisa, Nicholas Boddicker, Chunling Hu, Siddhartha Yadav, Jeffrey N. Weitzel, Peter Kraft, Susan M. Domchek, Fergus J. Couch, Katherine L. Nathanson, for the CARRIERS Consortium
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 1183.
https://doi.org/10.1158/1538-7445.AM2023-1183
Published: 04 April 2023
View article titled, Abstract 1183: Mutation type and location in breast cancer susceptibility genes are associated with differential risk in the general population
Journal Articles

Abstract 5243: Functional characterization of genetic loci in basal cell carcinoma

Mingyue Li, Constance Turman, Peter Kraft, Jiali Han
Journal: Cancer Research
Cancer Res (2023) 83 (7_Supplement): 5243.
https://doi.org/10.1158/1538-7445.AM2023-5243
Published: 04 April 2023
View article titled, Abstract 5243: Functional characterization of genetic loci in basal cell carcinoma
Journal Articles

Abstract GS4-04: Population-based Estimates of contralateral Breast Cancer Risk among Carriers of Germline Pathogenic Variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2

Siddhartha Yadav, Nicholas J. Boddicker, Jie Na, Eric C. Polley, Chunling Hu, Steven N. Hart, Rohan D. Gnanaolivu, Nicole Larson, Carolyn Dunn, Susan Holtegaard, Huaizhi Huang, Lauren R. Teras, Alpa V. Patel, James V. Lacey, Jr., Susan Neuhausen, Leslie Bernstein, Elena Martinez, Christopher Haiman, Fei Chen, Kathryn Ruddy, Janet Olson, Esther John, Allison W. Kurian, Dale P. Sandler, Katie M. O’Brien, Jack A. Taylor, Clarice R. Weinberg, Hoda Anton-Culver, Argyrios Ziogas, Gary R. Zirpoli, David E. Goldgar, Katherine L. Nathanson, Susan Domchek, Julie R. Palmer, Jeffrey Weitzel, Peter Kraft, Fergus J. Couch
Journal: Cancer Research
Cancer Res (2023) 83 (5_Supplement): GS4-04.
https://doi.org/10.1158/1538-7445.SABCS22-GS4-04
Published: 01 March 2023
View article titled, Abstract GS4-04: Population-based Estimates of contralateral Breast Cancer Risk among Carriers of Germline Pathogenic Variants in ATM, BRCA1, BRCA2, CHEK2, and PALB2
Journal Articles

Abstract 5891: The age-dependent association of risk factors with pancreatic cancer

Chen Yuan, Jihye Kim, Qiao-Li Wang, Alice A. Lee, Ana Babic, PanScan/PanC4 I-III Consortium, Laufey T. Amundadottir, Alison P. Klein, Donghui Li, Marjorie L. McCullough, Gloria M. Petersen, Harvey A. Risch, Rachael Z. Stolzenberg-Solomon, Kimberly Perez, Kimmie Ng, Edward L. Giovannucci, Meir J. Stampfer, Peter Kraft, Brian M. Wolpin
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5891.
https://doi.org/10.1158/1538-7445.AM2022-5891
Published: 15 June 2022
View article titled, Abstract 5891: The age-dependent association of risk factors with pancreatic cancer
Journal Articles

Abstract 5934: Weight loss and subsequent cancer diagnosis: A prospective cohort study

Qiao-Li Wang, Ana Babic, Michael H. Rosenthal, Alice A. Lee, Yin Zhang, Xuehong Zhang, Mingyang Song, Leandro F. Rezende, Dong Hoon Lee, Leah Biller, Kimmie Ng, Andrew T. Chan, Meir J. Stampfer, Edward L. Giovannucci, Peter Kraft, Chen Yuan, Brian M. Wolpin
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5934.
https://doi.org/10.1158/1538-7445.AM2022-5934
Published: 15 June 2022
View article titled, Abstract 5934: Weight loss and subsequent cancer diagnosis: A prospective cohort study
Journal Articles

Abstract 2256: Validation of an integrated breast cancer risk model with mammographic density in three prospective cohort studies

Charlotta V. Mulder, Yon Ho Jee, Xin Yang, Christopher G. Scott, Chi Gao, Amber N. Hurson, Mikael Eriksson, Per Hall, Peter Kraft, Celine M. Vachon, Antonis C. Antoniou, Gretchen Gierach, Montserrat Garcia-Closas, Parichoy Pal Choudhury
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 2256.
https://doi.org/10.1158/1538-7445.AM2022-2256
Published: 15 June 2022
View article titled, Abstract 2256: Validation of an integrated breast cancer risk model with mammographic density in three prospective cohort studies
Journal Articles

Abstract 5903: Polygenic risk scores for prediction of breast cancer in Korean women

Yon Ho Jee, Weang-Kee Ho, Sohee Park, Douglas Easton, Soo-Hwang Teo, Keum Ji Jung, Peter Kraft
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): 5903.
https://doi.org/10.1158/1538-7445.AM2022-5903
Published: 15 June 2022
View article titled, Abstract 5903: Polygenic risk scores for prediction of breast cancer in Korean women
Journal Articles

Abstract LB550: AI predicts risk of pancreatic cancer from disease trajectories using real-world electronic health records (EHRs) from Denmark and the USA

Davide Placido, Bo Yuan, Jessica X. Hjaltelin, Amalie D. Haue, Piotr J. Chmura, Chen Yuan, Jihye Kim, Renato Umeton, Gregory Antell, Alexander Chowdhury, Alexandra Franz, Lauren Brais, Elizabeth Andrews, Debora S. Marks, Aviv Regev, Peter Kraft, Brian M. Wolpin, Michael Rosenthal, Søren Brunak, Chris Sander
Journal: Cancer Research
Cancer Res (2022) 82 (12_Supplement): LB550.
https://doi.org/10.1158/1538-7445.AM2022-LB550
Published: 15 June 2022
View article titled, Abstract LB550: AI predicts risk of pancreatic cancer from disease trajectories using real-world electronic health records (EHRs) from Denmark and the USA
Journal Articles

Abstract P3-13-02: A genome-wide association study of mammographic texture variation

Yuxi Liu, Xia Jiang, Constance Turman, Celine M Vachon, Rulla Tamimi, Peter Kraft
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P3-13-02.
https://doi.org/10.1158/1538-7445.SABCS21-P3-13-02
Published: 15 February 2022
View article titled, Abstract P3-13-02: A genome-wide association study of mammographic texture variation
Journal Articles

Abstract P2-09-01: Population-based risk estimates of clinical subtypes of breast cancer among carriers of germline pathogenic variants in cancer predisposition genes

Siddhartha Yadav, Chunling Hu, Nicholas J. Boddicker, Eric Polley, Steven Hart, Rohan Gnanaolivu, Jie Na, Hongyan Huang, Song Yao, Celine M. Vachon, Lauren Teras, Jack A. Taylor, Dale P. Sandler, Julie R. Palmer, Janet E. Olson, Susan Neuhausen, Elena Martinez, Sara Lindstroem, Loic Le Marchand, Charles Kooperberg, Christopher Haiman, Mia M. Gaudet, James V. Lacey, Kimberly A. Bertrand, Leslie Bernstein, Paul W. Auer, Christine Ambrosone, Jeffrey N. Weitzel, Peter Kraft, David E. Goldgar, Katherine L. Nathanson, Susan M. Domchek, Fergus J. Couch, CARRIERS Consortium
Journal: Cancer Research
Cancer Res (2022) 82 (4_Supplement): P2-09-01.
https://doi.org/10.1158/1538-7445.SABCS21-P2-09-01
Published: 15 February 2022
View article titled, Abstract P2-09-01: Population-based risk estimates of clinical subtypes of breast cancer among carriers of germline pathogenic variants in cancer predisposition genes
Journal Articles

Abstract 826: Large-scale genome-wide association study identifies multiple novel germline susceptibility variants associated with bladder cancer risk

Stella Koutros, Lambertus A. Kiemeney, Roger L. Milne, Yuanqing Ye, Vijai Joseph, Jonine Figueroa, Nilanjan Chatterjee, Graham G. Giles, Michelle A. Hildebrandt, Lars Dyrskjot, Kenneth Offit, Manolis Kogevinas, Elisabete Weiderpass, Marjorie L. McCullough, Neal D. Freedman, Demetrius Albanes, Charles Kooperberg, Victoria Cortessis, Margaret R. Karagas, Dalsu Baris, Alison Johnson, Molly R. Schwenn, Helena Furberg, Dean F. Bajorin, Parichoy Pal Choudhury, Oscar Florez-Vargas, Olivier Cussenot, Geraldine Cancel-Tassin, Simone Benhamou, Peter Kraft, Stefano Porru, Mark P. Purdue, Katherine A. McGlynn, Cari M. Kitahara, Christopher A. Haiman, Mark H. Greene, Thorunn Rafnar, Stephen J. Chanock, Xifeng Wu, Francisco X. Real, Debra T. Silverman, Montserrat Garcia-Closas, Kari Stefansson, Ludmila Prokunina-Olsson, Nuria Malats, Nathaniel Rothman
Journal: Cancer Research
Cancer Res (2021) 81 (13_Supplement): 826.
https://doi.org/10.1158/1538-7445.AM2021-826
Published: 01 July 2021
View article titled, Abstract 826: Large-scale genome-wide association study identifies multiple novel germline susceptibility variants associated with bladder cancer risk
Journal Articles

Smoking Modifies Pancreatic Cancer Risk Loci on 2q21.3

Evelina Mocci, Prosenjit Kundu, William Wheeler, Alan A. Arslan, Laura E. Beane-Freeman, Paige M. Bracci, Paul Brennan, Federico Canzian, Mengmeng Du, Steven Gallinger, Graham G. Giles, Phyllis J. Goodman, Charles Kooperberg, Loic Le Marchand, Rachel E. Neale, Xiao-Ou Shu, Kala Visvanathan, Emily White, Wei Zheng, Demetrius Albanes, Gabriella Andreotti, Ana Babic, William R. Bamlet, Sonja I. Berndt, Amanda L. Blackford, Bas Bueno-de-Mesquita, Julie E. Buring, Daniele Campa, Stephen J. Chanock, Erica J. Childs, Eric J. Duell, Charles S. Fuchs, J. Michael Gaziano, Edward L. Giovannucci, Michael G. Goggins, Patricia Hartge, Manal M. Hassan, Elizabeth A. Holly, Robert N. Hoover, Rayjean J. Hung, Robert C. Kurtz, I-Min Lee, Núria Malats, Roger L. Milne, Kimmie Ng, Ann L. Oberg, Salvatore Panico, Ulrike Peters, Miquel Porta, Kari G. Rabe, Elio Riboli, Nathaniel Rothman, Ghislaine Scelo, Howard D. Sesso, Debra T. Silverman, Victoria L. Stevens, Oliver Strobel, Ian M. Thompson, Jr, Anne Tjonneland, Antonia Trichopoulou, Stephen K. Van Den Eeden, Jean Wactawski-Wende, Nicolas Wentzensen, Lynne R. Wilkens, Herbert Yu, Fangcheng Yuan, Anne Zeleniuch-Jacquotte, Laufey T. Amundadottir, Donghui Li, Eric J. Jacobs, Gloria M. Petersen, Brian M. Wolpin, Harvey A. Risch, Peter Kraft, Nilanjan Chatterjee, Alison P. Klein, Rachael Stolzenberg-Solomon
Journal: Cancer Research
Cancer Res (2021) 81 (11): 3134–3143.
https://doi.org/10.1158/0008-5472.CAN-20-3267
Published: 01 June 2021
View article titled, Smoking Modifies Pancreatic Cancer Risk Loci on 2q21.3
Open the PDF for Smoking Modifies Pancreatic Cancer Risk Loci on 2q21.3 in another window
Includes: Supplementary data
Journal Articles

Abstract 30: Cross-cancer cross-tissue transcriptome-wide association study (TWAS) of 11 cancers identifies 56 novel genes

Helian Feng, Arunabha Majumdar, Bogdan Pasaniuc, Hongjie Chen, Sara Lindström, BCAC, OCAC, PRACTICAL, Jeroen Huyghe, Stephanie L. Schmit, Tracy A. O'Mara, Deborah J. Thompson, Stuart MacGregor, Paul Brennan, James McKay, Richard S. Houlston, Beatrice S. Melin, Christopher Amos, Anne E. Cus, Mark M. Iles, Siddhartha Kar, Paul Pharoah, Rayjean J. Hung, Peter Kraft
Journal: Cancer Research
Cancer Res (2020) 80 (16_Supplement): 30.
https://doi.org/10.1158/1538-7445.AM2020-30
Published: 15 August 2020
View article titled, Abstract 30: Cross-cancer cross-tissue transcriptome-wide association study (TWAS) of 11 cancers identifies 56 novel genes