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Abstract 1076: Sharing data from the Human Tumor Atlas Network through standards, infrastructure, and community engagement

Cancer Res (2025) 85 (8_Supplement_1): 1076.

https://doi.org/10.1158/1538-7445.AM2025-1076

Published: 21 April 2025

View articletitled, Abstract 1076: Sharing data from the Human Tumor Atlas Network through standards, infrastructure, and community engagement

Journal Articles

Abstract 5014: Integrative molecular and spatial analysis to reveal tumor intrinsic and extrinsic drivers of immunotherapy response in mucosal melanoma

Yingxiao Shi, Tuulia Vallius, Aikaterini Dedeilia, Roxanne Pelletier, Jia-Ren Lin, Mariana Lopez Leon, Christine Lian, Shishir Pant, Giuseppe Tarantino, Annette Wang, Jiajia Chen, Elizabeth I. Buchbinder, Peter K. Sorger, David Liu, Genevieve M. Boland

Cancer Res (2025) 85 (8_Supplement_1): 5014.

https://doi.org/10.1158/1538-7445.AM2025-5014

Published: 21 April 2025

View articletitled, Abstract 5014: Integrative molecular and spatial analysis to reveal tumor intrinsic and extrinsic drivers of immunotherapy response in mucosal melanoma

Journal Articles

Abstract 7152: High-dimensional, single-cell analysis and transcriptional profiling reveal novel correlatives of response to PARP inhibition plus PD-1 blockade in triple-negative breast cancer

Cancer Res (2025) 85 (8_Supplement_1): 7152.

https://doi.org/10.1158/1538-7445.AM2025-7152

Published: 21 April 2025

View articletitled, Abstract 7152: High-dimensional, single-cell analysis and transcriptional profiling reveal novel correlatives of response to PARP inhibition plus PD-1 blockade in triple-negative breast cancer

Journal Articles

Abstract 1172: An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer

Cancer Res (2025) 85 (8_Supplement_1): 1172.

https://doi.org/10.1158/1538-7445.AM2025-1172

Published: 21 April 2025

View articletitled, Abstract 1172: An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer

Journal Articles

Abstract CT007: Phase 1/2 trial of copanlisib in combination with nivolumab for microsatellite stable (MSS) colorectal cancer (CRC)

Eric S. Christenson, Jeremiah A. Wala, Rose Parkinson, Natalie B. Collins, Christopher Jakubowski, Jea-Ren Lin, Hao Wang, Won Jin Ho, Sabrina Chan, Rachel Klein, Yvette Cetasaan, Emma Johnson, Maureen Berg, Jeffrey Meyerhardt, Benjamin Schlechter, Harshabad Singh, Peter K. Sorger, Marios Giannakis, Nilofer Azad

Cancer Res (2024) 84 (7_Supplement): CT007.

https://doi.org/10.1158/1538-7445.AM2024-CT007

Published: 05 April 2024

View articletitled, Abstract CT007: Phase 1/2 trial of copanlisib in combination with nivolumab for microsatellite stable (MSS) colorectal cancer (CRC)

Journal Articles

Abstract LB311: Multimodal spatial profiling reveals the emergence of an immune suppressive microenvironment at the initial stages of high-grade serous ovarian cancer development

Tanjina Kader, Jia-Ren Lin, Shannon Coy, Clemens Hug, Yu-An Chen, Roxanne J. Pelletier, Mariana Leon, John Lee, Yi-Lin Xu, Clarence Yapp, Natalie Shih, Gabriel Mingo, Euihye Jung, Srishti Rathore, Judith Agudo, Charles Drescher, Peter K. Sorger, Ronny Drapkin, Sandro Santagata

Cancer Res (2024) 84 (7_Supplement): LB311.

https://doi.org/10.1158/1538-7445.AM2024-LB311

Published: 05 April 2024

View articletitled, Abstract LB311: Multimodal spatial profiling reveals the emergence of an immune suppressive microenvironment at the initial stages of high-grade serous ovarian cancer development

Journal Articles

Abstract 109: Identification of tumor-intrinsic and extrinsic mechanisms of T cell exclusion in estrogen receptor-positive (ER+) breast cancer through integration of bulk and single-cell transcriptome and spatial analysis

Kenichi Shimada, Yvonne X. Cui, Daniel Michaud, Kelly F. Zheng, Jonathan Goldberg, Ricardo Pastorello, Lukas Kania, Sandra S. McAllister, Sara M. Tolaney, Adrienne Waks, Rinath Jeselsohn, Peter K. Sorger, Judith Agudo, Jennifer L. Guerriero, Elizabeth A. Mittendorf

Cancer Res (2024) 84 (6_Supplement): 109.

https://doi.org/10.1158/1538-7445.AM2024-109

Published: 22 March 2024

View articletitled, Abstract 109: Identification of tumor-intrinsic and extrinsic mechanisms of T cell exclusion in estrogen receptor-positive (ER+) breast cancer through integration of bulk and single-cell transcriptome and spatial analysis

Journal Articles

Abstract B073: A spatially resolved single-cell tumor microenvironment of clinicomolecular subtypes of high-grade serous ovarian cancer

Fernando Perez-Villatoro, Lilian van Wagensveld, Aleksandra Shabanova, Siamak Hajizadeh, Julia Casado, Ella Anttila, Maaike A. van der Aa, Roy F.P.M. Kruitwagen, Gabe S. Sonke, Koen K. Van de Vijver, Peter K. Sorger, Hugo M. Horlings, Anniina Färkkilä

Cancer Res (2024) 84 (5_Supplement_2): B073.

https://doi.org/10.1158/1538-7445.OVARIAN23-B073

Published: 04 March 2024

View articletitled, Abstract B073: A spatially resolved single-cell tumor microenvironment of clinicomolecular subtypes of high-grade serous ovarian cancer

Journal Articles

Abstract 6618: Longitudinal, multimodal profiling of metastatic ER+ breast cancer on CDK4/6 inhibitor therapy

Allison L. Creason, Julian Egger, Cameron Watson, Shamilene Sivagnanam, Jia-Ren Lin, Koei Chin, Peter K. Sorger, Lisa M. Coussens, Zahi I. Mitri, Joe W. Gray, Gordon B. Mills, Jeremy Goecks

Cancer Res (2023) 83 (7_Supplement): 6618.

https://doi.org/10.1158/1538-7445.AM2023-6618

Published: 04 April 2023

View articletitled, Abstract 6618: Longitudinal, multimodal profiling of metastatic ER+ breast cancer on CDK4/6 inhibitor therapy

Journal Articles

Abstract 5877: Intratumoral lymphocyte networks harbor TCF1+ PD1+ progenitor CD8 T cells in lung cancer

Megan L. Burger, Giorgio Gaglia, Claire C. Ritch, Danae Rammos, Yang Dai, Grace E. Crossland, Sara Z. Tavana, Simon Warchol, Alex M. Jaeger, Santiago Naranjo, Shannon Coy, Ajit J. Nirmal, Robert Krueger, Jia-Ren Lin, Hanspeter Pfister, Peter K. Sorger, Tyler Jacks, Sandro Santagata

Cancer Res (2023) 83 (7_Supplement): 5877.

https://doi.org/10.1158/1538-7445.AM2023-5877

Published: 04 April 2023

View articletitled, Abstract 5877: Intratumoral lymphocyte networks harbor TCF1+ PD1+ progenitor CD8 T cells in lung cancer

Journal Articles

Abstract 3514: A genetic-metabolic circuit of liver-specific metastatic organotropism

Cancer Res (2023) 83 (7_Supplement): 3514.

https://doi.org/10.1158/1538-7445.AM2023-3514

Published: 04 April 2023

View articletitled, Abstract 3514: A genetic-metabolic circuit of liver-specific metastatic organotropism

Journal Articles

Abstract 981: A genetic-metabolic axis of metastatic liver organotropism

Cancer Res (2022) 82 (12_Supplement): 981.

https://doi.org/10.1158/1538-7445.AM2022-981

Published: 15 June 2022

View articletitled, Abstract 981: A genetic-metabolic axis of metastatic liver organotropism

Journal Articles

Abstract LB056: The spatial landscape of progression and immunoediting in primary melanoma at single cell resolution

Ajit Johnson Nirmal, Zoltan Maliga, Tuulia Vallius, Brian Quattrochi, Alyce Chen, Connor Jacobson, Roxanne Pelletier, Clarence Yapp, Raquel Arias-Camison, Yu-An Chen, Christine Lian, George F. Murphy, Sandro Santagata, Peter K. Sorger

Cancer Res (2022) 82 (12_Supplement): LB056.

https://doi.org/10.1158/1538-7445.AM2022-LB056

Published: 15 June 2022

View articletitled, Abstract LB056: The spatial landscape of progression and immunoediting in primary melanoma at single cell resolution

Journal Articles

Abstract P4-04-06: Integrative analysis of single-cell transcriptomic and spatial profiles characterized distinct tumor microenvironment phenotypes in hormone receptor positive (HR+) breast cancer

Kenichi Shimada, Yvonne X Cui, Jonathan S Goldberg, Ricardo Pastorello, Janae Davis, Tuulia Vallius, Lukas Kania, Ashka Patel, Mckenna Moore, Esther R Ogayo, Deborah Dillon, Peter K Sorger, Jennifer L Guerriero, Elizabeth A Mittendorf

Cancer Res (2022) 82 (4_Supplement): P4-04-06.

https://doi.org/10.1158/1538-7445.SABCS21-P4-04-06

Published: 15 February 2022

View articletitled, Abstract P4-04-06: Integrative analysis of single-cell transcriptomic and spatial profiles characterized distinct tumor microenvironment phenotypes in hormone receptor positive (HR+) breast cancer

Journal Articles

Abstract P2-07-13: High-dimensional, single-cell analysis and transcriptional profiling reveal novel correlatives of response to PARP inhibition plus PD-1 blockade in triple-negative breast cancer

Cancer Res (2022) 82 (4_Supplement): P2-07-13.

https://doi.org/10.1158/1538-7445.SABCS21-P2-07-13

Published: 15 February 2022

View articletitled, Abstract P2-07-13: High-dimensional, single-cell analysis and transcriptional profiling reveal novel correlatives of response to PARP inhibition plus PD-1 blockade in triple-negative breast cancer

Journal Articles

Abstract 482: Rapid highly multiplexed immunoprofiling of human fixed tissues by Orion imaging

Jia-Ren Lin, Daniel E. Campton, Jeremy Cooper, Yu-An Chen, Erin F. McCarty, Keith L. Ligon, Eric P. Kaldjian, Kyla Teplitz, Steve Reese, Sandro Santagata, Peter K. Sorger

Cancer Res (2021) 81 (13_Supplement): 482.

https://doi.org/10.1158/1538-7445.AM2021-482

Published: 01 July 2021

View articletitled, Abstract 482: Rapid highly multiplexed immunoprofiling of human fixed tissues by Orion imaging

Journal Articles

Abstract 4: Temporal and spatial topography of cell proliferation in cancer

Giorgio Gaglia, Sheheryar Kabraji, Danae Argyropoulou, Yang Dai, Johann Bergholz, Shannon Coy, Jia-Ren Lin, Eric P. Winer, Deborah Dillon, Jean J. Zhao, Peter K. Sorger, Sandro Santagata

Cancer Res (2021) 81 (13_Supplement): 4.

https://doi.org/10.1158/1538-7445.AM2021-4

Published: 01 July 2021

View articletitled, Abstract 4: Temporal and spatial topography of cell proliferation in cancer

Journal Articles

Abstract 2747: Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer

Inga-Maria P. Launonen, Nuppu Lyytikäinen, Julia Casado, Ella A. Anttila, Connor A. Jacobson, Jia R. Lin, Zoltan Maliga, Sandro Santaga, Kevin M. Elias, Alan D. D'Andrea, Panagiotis A. Konstantinopoulos, Peter K. Sorger, Anniina Färkkilä

Cancer Res (2021) 81 (13_Supplement): 2747.

https://doi.org/10.1158/1538-7445.AM2021-2747

Published: 01 July 2021

View articletitled, Abstract 2747: Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer

Journal Articles

Abstract 1816: Phenogenomic characterization of immunomodulatory purinergic signaling in glioblastoma

Shannon Coy, Jia-Ren Lin, Shu Wang, Sylwia Stopka, Rumana Rashid, Jaeho Hwang, Prasidda Khadka, Philipp Euskirchen, Pratiti Bandopadhayay, Patrick Y. Wen, Peter K. Sorger, Nathalie Agar, Keith L. Ligon, Mehdi Touat, Sandro Santagata

Cancer Res (2021) 81 (13_Supplement): 1816.

https://doi.org/10.1158/1538-7445.AM2021-1816

Published: 01 July 2021

View articletitled, Abstract 1816: Phenogenomic characterization of immunomodulatory purinergic signaling in glioblastoma

Journal Articles

Heterogeneity and Clonal Evolution of Acquired PARP Inhibitor Resistance in TP53- and BRCA1-Deficient Cells

Anniina Färkkilä, Alfredo Rodríguez, Jaana Oikkonen, Doga C. Gulhan, Huy Nguyen, Julieta Domínguez, Sandra Ramos, Caitlin E. Mills, Fernando Pérez-Villatoro, Jean-Bernard Lazaro, Jia Zhou, Connor S. Clairmont, Lisa A. Moreau, Peter J. Park, Peter K. Sorger, Sampsa Hautaniemi, Sara Frias, Alan D. D'Andrea

Cancer Res (2021) 81 (10): 2774–2787.

https://doi.org/10.1158/0008-5472.CAN-20-2912

Published: 15 May 2021

View articletitled, Heterogeneity and Clonal Evolution of Acquired PARP Inhibitor Resistance in TP53- and BRCA1-Deficient Cells

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Abstract 1076: Sharing data from the Human Tumor Atlas Network through standards, infrastructure, and community engagement

Abstract 5014: Integrative molecular and spatial analysis to reveal tumor intrinsic and extrinsic drivers of immunotherapy response in mucosal melanoma

Abstract 7152: High-dimensional, single-cell analysis and transcriptional profiling reveal novel correlatives of response to PARP inhibition plus PD-1 blockade in triple-negative breast cancer

Abstract 1172: An estrogen receptor signaling transcriptional program linked to immune evasion in human hormone receptor-positive breast cancer

Abstract CT007: Phase 1/2 trial of copanlisib in combination with nivolumab for microsatellite stable (MSS) colorectal cancer (CRC)

Abstract LB311: Multimodal spatial profiling reveals the emergence of an immune suppressive microenvironment at the initial stages of high-grade serous ovarian cancer development

Abstract 109: Identification of tumor-intrinsic and extrinsic mechanisms of T cell exclusion in estrogen receptor-positive (ER+) breast cancer through integration of bulk and single-cell transcriptome and spatial analysis

Abstract B073: A spatially resolved single-cell tumor microenvironment of clinicomolecular subtypes of high-grade serous ovarian cancer

Abstract 6618: Longitudinal, multimodal profiling of metastatic ER+ breast cancer on CDK4/6 inhibitor therapy

Abstract 5877: Intratumoral lymphocyte networks harbor TCF1+ PD1+ progenitor CD8 T cells in lung cancer

Abstract 3514: A genetic-metabolic circuit of liver-specific metastatic organotropism

Abstract 981: A genetic-metabolic axis of metastatic liver organotropism

Abstract LB056: The spatial landscape of progression and immunoediting in primary melanoma at single cell resolution

Abstract P4-04-06: Integrative analysis of single-cell transcriptomic and spatial profiles characterized distinct tumor microenvironment phenotypes in hormone receptor positive (HR+) breast cancer

Abstract P2-07-13: High-dimensional, single-cell analysis and transcriptional profiling reveal novel correlatives of response to PARP inhibition plus PD-1 blockade in triple-negative breast cancer

Abstract 482: Rapid highly multiplexed immunoprofiling of human fixed tissues by Orion imaging

Abstract 4: Temporal and spatial topography of cell proliferation in cancer

Abstract 2747: Single-cell tumor-immune microenvironment of BRCA1/2 mutated high-grade serous ovarian cancer

Abstract 1816: Phenogenomic characterization of immunomodulatory purinergic signaling in glioblastoma

Heterogeneity and Clonal Evolution of Acquired PARP Inhibitor Resistance in TP53- and BRCA1-Deficient Cells

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