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Peter J. Parker
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Journal Articles

Genome-Protective Topoisomerase 2a-Dependent G2 Arrest Requires p53 in hTERT-Positive Cancer Cells

Nicola Lockwood, Silvia Martini, Ainara Lopez-Pardo, Katharina Deiss, Hendrika A. Segeren, Robert K. Semple, Ian Collins, Dimitra Repana, Mathias Cobbaut, Tanya Soliman, Francesca Ciccarelli, Peter J. Parker
Journal: Cancer Research
Cancer Res (2022) 82 (9): 1762–1773.
https://doi.org/10.1158/0008-5472.CAN-21-1785
Published: 03 May 2022
View article titled, Genome-Protective Topoisomerase 2a-Dependent G<sub>2</sub> Arrest Requires p53 in hTERT-Positive Cancer Cells
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Includes: Supplementary data
Journal Articles

High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment

Lissete Sánchez-Magraner, James Miles, Claire L. Baker, Christopher J. Applebee, Dae-Jin Lee, Somaia Elsheikh, Shaimaa Lashin, Katriona Withers, Andrew G. Watts, Richard Parry, Christine Edmead, Jose Ignacio Lopez, Raj Mehta, Antoine Italiano, Stephen G. Ward, Peter J. Parker, Banafshé Larijani
Journal: Cancer Research
Series: Author Choice
Cancer Res (2020) 80 (19): 4244–4257.
https://doi.org/10.1158/0008-5472.CAN-20-1117
Published: 02 October 2020
View article titled, High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment
Open the PDF for High PD-1/PD-L1 Checkpoint Interaction Infers Tumor Selection and Therapeutic Sensitivity to Anti-PD-1/PD-L1 Treatment in another window
Includes: Supplementary data
Journal Articles

The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers

Brandon Leonard, Jennifer L. McCann, Gabriel J. Starrett, Leah Kosyakovsky, Elizabeth M. Luengas, Amy M. Molan, Michael B. Burns, Rebecca M. McDougle, Peter J. Parker, William L. Brown, Reuben S. Harris
Journal: Cancer Research
Cancer Res (2015) 75 (21): 4538–4547.
https://doi.org/10.1158/0008-5472.CAN-15-2171-T
Published: 01 November 2015
View article titled, The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers
Open the PDF for The PKC/NF-κB Signaling Pathway Induces APOBEC3B Expression in Multiple Human Cancers in another window
Includes: Supplementary data
Journal Articles

Abstract LB-99: Identification and characterization of small molecule thieno[3,2-d]pyrimidine inhibitors of Protein Kinase C iota (PKCι)

Christelle Soudy, Emma Stanway, Bhavisha Patel, Caroline Barton, Michelle Barnard, Leon Pang, Paul Owen, Andrew Turnbull, Bruce A. Ruggeri, Bruce D. Dorsey, Mark A. Ator, Greg R. Ott, Mark Linch, Philippe Riou, Peter J. Parker, Sven Kjaer, Christian Dillon, Neil Q. McDonald, Jon Roffey
Journal: Cancer Research
Cancer Res (2014) 74 (19_Supplement): LB-99.
https://doi.org/10.1158/1538-7445.AM2014-LB-99
Published: 01 October 2014
View article titled, Abstract LB-99: Identification and characterization of small molecule thieno[3,2-d]pyrimidine inhibitors of Protein Kinase C iota (PKCι)
Journal Articles

High-Throughput Time-Resolved FRET Reveals Akt/PKB Activation as a Poor Prognostic Marker in Breast Cancer

Selvaraju Veeriah, Pierre Leboucher, Julien de Naurois, Nirmal Jethwa, Emma Nye, Tamara Bunting, Richard Stone, Gordon Stamp, Véronique Calleja, Stefanie S. Jeffrey, Peter J. Parker, Banafshé Larijani
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (18): 4983–4995.
https://doi.org/10.1158/0008-5472.CAN-13-3382
Published: 14 September 2014
View article titled, High-Throughput Time-Resolved FRET Reveals Akt/PKB Activation as a Poor Prognostic Marker in Breast Cancer
Open the PDF for High-Throughput Time-Resolved FRET Reveals Akt/PKB Activation as a Poor Prognostic Marker in Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER+ Breast Cancer

David Endesfelder, Rebecca A. Burrell, Nnennaya Kanu, Nicholas McGranahan, Mike Howell, Peter J. Parker, Julian Downward, Charles Swanton, Maik Kschischo
Journal: Cancer Research
Series: Author Choice
Cancer Res (2014) 74 (17): 4853–4863.
https://doi.org/10.1158/0008-5472.CAN-13-2664
Published: 01 September 2014
View article titled, Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER<sup>+</sup> Breast Cancer
Open the PDF for Chromosomal Instability Selects Gene Copy-Number Variants Encoding Core Regulators of Proliferation in ER<sup>+</sup> Breast Cancer in another window
Includes: Supplementary data
Journal Articles

Prognostic Value of an Activation State Marker for Epidermal Growth Factor Receptor in Tissue Microarrays of Head and Neck Cancer

Anthony Kong, Pierre Leboucher, Russell Leek, Véronique Calleja, Stuart Winter, Adrian Harris, Peter J. Parker, Banafshé Larijani
Journal: Cancer Research
Cancer Res (2006) 66 (5): 2834–2843.
https://doi.org/10.1158/0008-5472.CAN-05-2994
Published: 01 March 2006
View article titled, Prognostic Value of an Activation State Marker for Epidermal Growth Factor Receptor in Tissue Microarrays of Head and Neck Cancer
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Journal Articles

Modulation of Protein Kinase C-ε by Phorbol Esters in the Monoblastoid U937 Cell

D. Kirk Ways, Berniece R. Messer, Trudy O. Garris, Weixi Qin, Paul P. Cook, Peter J. Parker
Journal: Cancer Research
Cancer Res (1992) 52 (20): 5604–5609.
Published: 01 October 1992
View article titled, Modulation of Protein Kinase C-ε by Phorbol Esters in the Monoblastoid U937 Cell
Open the PDF for Modulation of Protein Kinase C-ε by Phorbol Esters in the Monoblastoid U937 Cell in another window