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Peter Hokland
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Journal Articles

Abstract 1134: The tumor suppressor activity of miR-300 is detrimental for leukemia development but required for leukemia stem cell maintenance

Giovannino Silvestri, Lorenzo Stramucci, Justin Ellis, Jason Harb, Paolo Neviani, Bin Zhang, Klara Srutova, Gabriel Pineda, Catriona Jamieson, Bruno Calabretta, Fabio Stagno, Paolo Vigneri, Georgios Nteliopoulos, Philippa May, Alistar Reid, Ramiro Garzon, Denis-Claude Roy, Martin Guimond, Peter Hokland, Michael Deininger, Garrett Fitzgerald, Chris Harman, Francesco Dazzi, Dragana Milojkovic, Jane Apperley, Guido Marcucci, Jianfei Qi, Katerina Machova-Polakova, Xiaoxuan Fan, Maria Baer, Rossana Trotta, Danilo Perrotti
Journal: Cancer Research
Cancer Res (2018) 78 (13_Supplement): 1134.
https://doi.org/10.1158/1538-7445.AM2018-1134
Published: 01 July 2018
View article titled, Abstract 1134: The tumor suppressor activity of miR-300 is detrimental for leukemia development but required for leukemia stem cell maintenance
Journal Articles

Abstract 951: Role of the MSC-derived exosomal and endogenous JAK2-SET/PP2A-β-catenin-modulator miR-300 in leukemic stem/progenitor proliferation and survival in CML

Rossana Trotta, Giovannino Silvestri, Lorenzo Stramucci, Justin J. Ellis, Justine Yu, Jason J. Harb, Paolo Neviani, Guido Marcucci, Klara Srutova, Polakova K. Machova, Denis-Claude Roy, Peter Hokland, Michael Deininger, Ravi Bhatia, Carlo Gambacorti-Passerini, Dragana Milojkovic, Alistair Reid, Jane Apperley, Ferenc Livak, Jianfei Qi, Maria R. Baer, Danilo Perrotti
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 951.
https://doi.org/10.1158/1538-7445.AM2016-951
Published: 15 July 2016
View article titled, Abstract 951: Role of the MSC-derived exosomal and endogenous JAK2-SET/PP2A-β-catenin-modulator miR-300 in leukemic stem/progenitor proliferation and survival in CML
Journal Articles

Abstract 3648: Resolving copy number variations from existing exome SNP data without the need for sophisticated software

Marcus C. Hansen, Laura L. Herborg, Anne S. Roug, Sadudee Chotirat, Chirayu U. Auewarakul, Eigil Kjeldsen, Peter Hokland
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 3648.
https://doi.org/10.1158/1538-7445.AM2016-3648
Published: 15 July 2016
View article titled, Abstract 3648: Resolving copy number variations from existing exome SNP data without the need for sophisticated software
Journal Articles

Abstract 1169: Somatic MED12 mutations in hematological malignancies

Tuomas Heikkinen, Kati Kämpjärvi, Sirpa Leppä, Peter Hokland, Heikki Kuusanmäki, Satu Mustjoki, Marjatta Sinisalo, Caroline Heckman, Mika Kontro, Pia Vahteristo
Journal: Cancer Research
Cancer Res (2016) 76 (14_Supplement): 1169.
https://doi.org/10.1158/1538-7445.AM2016-1169
Published: 15 July 2016
View article titled, Abstract 1169: Somatic MED12 mutations in hematological malignancies
Journal Articles

Abstract 3454: Bcl-xL anti-apoptotic network is dispensable for emergence and maintenance of CML but required for disease progression, and represents an alternative target for halting survival of blast crisis CML progenitors.

Jason Harb, Paolo Neviani, Justin E. Ellis, Gregory J. Ferenchak, Brenda I. Chyla, Peter Hokland, Denis Claude Roy, Michael A. Caligiuri, Guido Marcucci, Claudia S. Huettner, Danilo Perrotti
Journal: Cancer Research
Cancer Res (2013) 73 (8_Supplement): 3454.
https://doi.org/10.1158/1538-7445.AM2013-3454
Published: 15 April 2013
View article titled, Abstract 3454: Bcl-xL anti-apoptotic network is dispensable for emergence and maintenance of CML but required for disease progression, and represents an alternative target for halting survival of blast crisis CML progenitors.
Journal Articles

Abstract LB-109: BCR-ABL1 kinase activity but not its expression is dispensable for Ph+ quiescent stem cell survival which depends on the PP2A-controlled Jak2 activation and is sensitive to FTY720 treatment

Paolo Neviani, Jason Harb, Joshua Oaks, Christopher Walker, Ramasamy Santhanam, Carolyn Paisie, Anna Eiring, Bin Zhang, Bastianella Perazzona, Y Ma, Charlene Mao, Guido Marcucci, Tessa Holyoake, Stefano Volinia, Jorge Cortes, Michael Caligiuri, Claudia Huettner, Robert Bittman, Ching-Shih Chen, Ralph Arlinghaus, Peter Hokland, Denis-Claude Roy, Ravi Bhatia, Danilo Perrotti
Journal: Cancer Research
Cancer Res (2011) 71 (8_Supplement): LB-109.
https://doi.org/10.1158/1538-7445.AM2011-LB-109
Published: 15 April 2011
View article titled, Abstract LB-109: BCR-ABL1 kinase activity but not its expression is dispensable for Ph+ quiescent stem cell survival which depends on the PP2A-controlled Jak2 activation and is sensitive to FTY720 treatment
Journal Articles

Abstract 1950: Suppression of RISC-independent decoy and RISC-mediated RNA-pairing activities of microRNA-328 is required for maturation-arrest and enhanced survival of blast crisis CML progenitors

Anna M. Eiring, Jason Harb, Paolo Neviani, Joshua J. Oaks, Shujun Liu, Riccardo Spizzo, Sebastian Schwind, Ramasamy Santhanam, Christopher Hickey, Heiko Becker, Jason C. Chandler, Raul Andino, Jorge Cortes, Peter Hokland, Claudia S. Huettner, Ravi Bhatia, Denis C. Roy, Stephen Liebhaber, Michael A. Caligiuri, Guido Marcucci, Ramiro Garzon, Carlo M. Croce, George A. Calin, Danilo Perrotti
Journal: Cancer Research
Cancer Res (2010) 70 (8_Supplement): 1950.
https://doi.org/10.1158/1538-7445.AM10-1950
Published: 15 April 2010
View article titled, Abstract 1950: Suppression of RISC-independent decoy and RISC-mediated RNA-pairing activities of microRNA-328 is required for maturation-arrest and enhanced survival of blast crisis CML progenitors
Journal Articles

Abstract #1075: PP2A induction by FTY720 inhibits survival and self-renewal of CD34+/CD38- CML stem cell through the simultaneous suppression of BCR/ABL and BCR/ABL-independent signals.

Paolo Neviani, Ramasamy Santhanam, Yihui Ma, Bin Zhang, Hsiaoyin Mao, Stefano Volinia, Guido Marcucci, Ching-Shih Chen, Jorge Cortes, Claudia Huettner, Steffen Koschmieder, Peter Hokland, Ravi Bhatia, Denis Roy, Michael Caligiuri, Danilo Perrotti
Journal: Cancer Research
Cancer Res (2009) 69 (9_Supplement): 1075.
Published: 01 May 2009
View article titled, Abstract #1075: PP2A induction by FTY720 inhibits survival and self-renewal of CD34+/CD38- CML stem cell through the simultaneous suppression of BCR/ABL and BCR/ABL-independent signals.
Journal Articles

Extensive Intra- and Interindividual Heterogeneity of p15INK4B Methylation in Acute Myeloid Leukemia

Anni Aggerholm, Per Guldberg, Marianne Hokland, Peter Hokland
Journal: Cancer Research
Cancer Res (1999) 59 (2): 436–441.
Published: 15 January 1999
View article titled, Extensive Intra- and Interindividual Heterogeneity of <sup><em>p15INK4B</em></sup> Methylation in Acute Myeloid Leukemia
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