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Journal Articles

Suppression of leukemia growth in vivo by a novel anti-FLT3 antibody-auristatin conjugate

Yiwen Li, Hongli Li, Mei-Nai Wang, Rajiv Bassi, Venkat Mangalampalli, Dale L. Ludwig, Paul Balderes, Larry Witte, Zhenping Zhu, Damon Meyer, Angelyn Larkin, Peter Senter, Peter Bohlen, Daniel J. Hicklin
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1455.
Published: 01 May 2005
View article titled, Suppression of leukemia growth in vivo by a novel anti-FLT3 antibody-auristatin conjugate
Journal Articles

Characterization of novel human monoclonal antibodies against melanoma associated antigen gp75/TRP-1

Dipa Patel, Armin Lahiji, Maxine Melchior, Stanley Ng, Rajiv Bassi, Yan Wu, Peter Bohlen, Daniel Hicklin, Xiaoqiang Kang
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 165.
Published: 01 May 2005
View article titled, Characterization of novel human monoclonal antibodies against melanoma associated antigen gp75/TRP-1
Journal Articles

Enhanced anti-tumor activity with cetuximab (ERBITUX®) in combination with oxaliplatin in human colon carcinoma xenografts

Marie Prewett, James R. Tonra, Rajiv Bassi, Francine Carrick, Genevieve Makhoul, Bridget Finnerty, Larry Witte, Peter Bohlen, Daniel J. Hicklin
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1192.
Published: 01 May 2005
View article titled, Enhanced anti-tumor activity with cetuximab (ERBITUX®) in combination with oxaliplatin in human colon carcinoma xenografts
Journal Articles

Activity of small molecule inhibitors of the epidermal growth factor receptor (EGFR) kinase, on EGFR kinase domain mutants

Jacqueline Doody, Robin Rolser, Sheetal Patel, Cindy Wang, Cindy Chiang, Kun Hu, Leon Smith, Sabina Burdzovic-Wizmann, Larry Witte, Peter Bohlen, Daniel J. Hicklin, Paul Kussie, Yaron R. Hadari
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1250.
Published: 01 May 2005
View article titled, Activity of small molecule inhibitors of the epidermal growth factor receptor (EGFR) kinase, on EGFR kinase domain mutants
Journal Articles

Inhibitory activity of the anti-epidermal growth factor receptor (EGFR) antibody Erbitux® on EGFR kinase domain mutants

Jacqueline Doody, Cindy Wang, Sheetal Patel, Robin Rolser, Cindy Chiang, Kun Hu, Michelle Iacolina, Larry Witte, Peter Bohlen, Daniel J. Hicklin, Paul Kussie, Yaron R. Hadari
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 1191–1192.
Published: 01 May 2005
View article titled, Inhibitory activity of the anti-epidermal growth factor receptor (EGFR) antibody Erbitux® on EGFR kinase domain mutants
Journal Articles

Specific VE-cadherin epitopes govern antiangiogenic or toxic responses to various VE-cadherin antibodies on tumor and normal vasculature

Chad May, Xiaohong Xu, Peter Chien Chen, Andrea Hooper, Rowena Almonte-Baldonado, Paul Kussie, Larry Shapiro, Daniel J. Hicklin, Peter Bohlen
Journal: Cancer Research
Cancer Res (2005) 65 (9_Supplement): 708.
Published: 01 May 2005
View article titled, Specific VE-cadherin epitopes govern antiangiogenic or toxic responses to various VE-cadherin antibodies on tumor and normal vasculature
Journal Articles

Fetal Stromal–Dependent Paracrine and Intracrine Vascular Endothelial Growth Factor-A/Vascular Endothelial Growth Factor Receptor-1 Signaling Promotes Proliferation and Motility of Human Primary Myeloma Cells

Loïc Vincent, David K. Jin, Matthias A. Karajannis, Koji Shido, Andrea T. Hooper, William K. Rashbaum, Bronislaw Pytowski, Yan Wu, Daniel J. Hicklin, Zhenping Zhu, Peter Bohlen, Ruben Niesvizky, Shahin Rafii
Journal: Cancer Research
Cancer Res (2005) 65 (8): 3185–3192.
https://doi.org/10.1158/0008-5472.CAN-04-3598
Published: 15 April 2005
View article titled, Fetal Stromal–Dependent Paracrine and Intracrine Vascular Endothelial Growth Factor-A/Vascular Endothelial Growth Factor Receptor-1 Signaling Promotes Proliferation and Motility of Human Primary Myeloma Cells
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Journal Articles

Angiogenesis Inhibition by Vascular Endothelial Growth Factor Receptor-2 Blockade Reduces Stromal Matrix Metalloproteinase Expression, Normalizes Stromal Tissue, and Reverts Epithelial Tumor Phenotype in Surface Heterotransplants

Silvia Vosseler, Nicolae Mirancea, Peter Bohlen, Margareta M. Mueller, Norbert E. Fusenig
Journal: Cancer Research
Cancer Res (2005) 65 (4): 1294–1305.
https://doi.org/10.1158/0008-5472.CAN-03-3986
Published: 25 February 2005
View article titled, Angiogenesis Inhibition by Vascular Endothelial Growth Factor Receptor-2 Blockade Reduces Stromal Matrix Metalloproteinase Expression, Normalizes Stromal Tissue, and Reverts Epithelial Tumor Phenotype in Surface Heterotransplants
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Journal Articles

Regulation of heparanase expression and secretion by protein kinase A and protein kinase C

Hua-Quan Miao, Elizabeth Navarro, Frank Schmitges, Yaron Hadari, Peter Bohlen, Paul Kussie
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 415–416.
Published: 01 April 2004
View article titled, Regulation of heparanase expression and secretion by protein kinase A and protein kinase C
Journal Articles

A fully human anti-FLT3 antibody (EB10) is efficacious in leukemia models expressing either wild-type or ITD-mutant FLT3 receptor

Yiwen Li, Mei-Nai Wang, Hongli Li, Dan Lu, Rajiv Bassi, Haifan Zhang, Dale Ludwig, Paul Balderes, Obdulio Piloto, Donald Small, Larry Witte, Peter Bohlen, Zhenping Zhu, Daniel Hicklin
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 692.
Published: 01 April 2004
View article titled, A fully human anti-FLT3 antibody (EB10) is efficacious in leukemia models expressing either wild-type or ITD-mutant FLT3 receptor
Journal Articles

A fully human monoclonal antibody against VEGFR-1 inhibits growth of human breast cancers

Yan Wu, Zhaojing Zhong, Huiling Li, James Huber, Rajiv Bassi, Andrea Hooper, Bridget Finnerty, Xenia Jimenez, Henry Koo, Paul Balderes, Dale Ludwig, Paul Kussie, Larry Witte, Peter Bohlen, Daniel J. Hicklin
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 694–695.
Published: 01 April 2004
View article titled, A fully human monoclonal antibody against VEGFR-1 inhibits growth of human breast cancers
Journal Articles

Identification and characterization of a fully human antibody directed against epidermal growth factor receptor for cancer therapy

Meilin Liu, Haifan Zhang, Xenia Jimenez, Dale Ludwig, Larry Witte, Peter Bohlen, Dan J. Hicklin, Zhenping Zhu
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 163.
Published: 01 April 2004
View article titled, Identification and characterization of a fully human antibody directed against epidermal growth factor receptor for cancer therapy
Journal Articles

Antitumor activity of a novel, human anti-epidermal growth factor receptor (EGFR) monoclonal antibody (IMC-11F8) in human tumor xenograft models

Marie Prewett, James R. Tonra, Bassi Rajiv, Andrea T. Hooper, Genevieve Makhoul, Bridget Finnerty, Larry Witte, Peter Bohlen, Zhenping Zhu, Daniel J. Hicklin
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1235.
Published: 01 April 2004
View article titled, Antitumor activity of a novel, human anti-epidermal growth factor receptor (EGFR) monoclonal antibody (IMC-11F8) in human tumor xenograft models
Journal Articles

Simultaneous blockade of both the epidermal growth factor receptor and the insulin-like growth factor receptor signaling pathways in cancer cells with a fully human recombinant bispecific antibody

Dan Lu, Haifan Zhang, Dale Ludwig, Anita Persaud, Xenia Jimenez, Douglas Burtrum, Paul Balderes, Meilin Liu, Peter Bohlen, Larry Witte, Zhenping Zhu
Journal: Cancer Research
Cancer Res (2004) 64 (7_Supplement): 1235.
Published: 01 April 2004
View article titled, Simultaneous blockade of both the epidermal growth factor receptor and the insulin-like growth factor receptor signaling pathways in cancer cells with a fully human recombinant bispecific antibody
Journal Articles

A Fully Human Monoclonal Antibody to the Insulin-Like Growth Factor I Receptor Blocks Ligand-Dependent Signaling and Inhibits Human Tumor Growth in Vivo

Douglas Burtrum, Zhenping Zhu, Dan Lu, Donna Marie Anderson, Marie Prewett, Daniel S. Pereira, Rajiv Bassi, Rashed Abdullah, Andrea T. Hooper, Henry Koo, Xenia Jimenez, Danielle Johnson, Robin Apblett, Paul Kussie, Peter Bohlen, Larry Witte, Daniel J. Hicklin, Dale L. Ludwig
Journal: Cancer Research
Cancer Res (2003) 63 (24): 8912–8921.
Published: 24 December 2003
View article titled, A Fully Human Monoclonal Antibody to the Insulin-Like Growth Factor I Receptor Blocks Ligand-Dependent Signaling and Inhibits Human Tumor Growth <em>in Vivo</em>
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Journal Articles

Sensitive Noninvasive Monitoring of Tumor Perfusion during Antiangiogenic Therapy by Intermittent Bolus-Contrast Power Doppler Sonography

Martin Krix, Fabian Kiessling, Silvia Vosseler, Nabeel Farhan, Margareta M. Mueller, Peter Bohlen, Norbert E. Fusenig, Stefan Delorme
Journal: Cancer Research
Cancer Res (2003) 63 (23): 8264–8270.
Published: 16 December 2003
View article titled, Sensitive Noninvasive Monitoring of Tumor Perfusion during Antiangiogenic Therapy by Intermittent Bolus-Contrast Power Doppler Sonography
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Journal Articles

Antitumor Effects in Mice of Low-dose (Metronomic) Cyclophosphamide Administered Continuously through the Drinking Water

Shan Man, Guido Bocci, Giulio Francia, Shane K. Green, Serge Jothy, Douglas Hanahan, Peter Bohlen, Daniel J. Hicklin, Gabriele Bergers, Robert S. Kerbel
Journal: Cancer Research
Cancer Res (2002) 62 (10): 2731–2735.
Published: 01 May 2002
View article titled, Antitumor Effects in Mice of Low-dose (Metronomic) Cyclophosphamide Administered Continuously through the Drinking Water
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Journal Articles

Selective Targeting of Angiogenic Tumor Vasculature by Vascular Endothelial-cadherin Antibody Inhibits Tumor Growth without Affecting Vascular Permeability

Fang Liao, Jacqueline F. Doody, Jay Overholser, Bridget Finnerty, Rajiv Bassi, Yan Wu, Elisabetta Dejana, Paul Kussie, Peter Bohlen, Daniel J. Hicklin
Journal: Cancer Research
Cancer Res (2002) 62 (9): 2567–2575.
Published: 01 May 2002
View article titled, Selective Targeting of Angiogenic Tumor Vasculature by Vascular Endothelial-cadherin Antibody Inhibits Tumor Growth without Affecting Vascular Permeability
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Includes: Supplementary data
Journal Articles

Complete Inhibition of Vascular Endothelial Growth Factor (VEGF) Activities with a Bifunctional Diabody Directed against Both VEGF Kinase Receptors, fms -like Tyrosine Kinase Receptor and Kinase Insert Domain-containing Receptor

Dan Lu, Xenia Jimenez, Haifan Zhang, Yan Wu, Peter Bohlen, Larry Witte, Zhenping Zhu
Journal: Cancer Research
Cancer Res (2001) 61 (19): 7002–7008.
Published: 01 October 2001
View article titled, Complete Inhibition of Vascular Endothelial Growth Factor (VEGF) Activities with a Bifunctional Diabody Directed against Both VEGF Kinase Receptors, <em>fms</em> -like Tyrosine Kinase Receptor and Kinase Insert Domain-containing Receptor
Open the PDF for Complete Inhibition of Vascular Endothelial Growth Factor (VEGF) Activities with a Bifunctional Diabody Directed against Both VEGF Kinase Receptors, <em>fms</em> -like Tyrosine Kinase Receptor and Kinase Insert Domain-containing Receptor in another window
Journal Articles

Inhibition of Glioma Angiogenesis and Growth in Vivo by Systemic Treatment with a Monoclonal Antibody against Vascular Endothelial Growth Factor Receptor-2

Philip Kunkel, Ulrike Ulbricht, Peter Bohlen, Marc A. Brockmann, Regina Fillbrandt, Dimitrios Stavrou, Manfred Westphal, Katrin Lamszus
Journal: Cancer Research
Cancer Res (2001) 61 (18): 6624–6628.
Published: 01 September 2001
View article titled, Inhibition of Glioma Angiogenesis and Growth <em>in Vivo</em> by Systemic Treatment with a Monoclonal Antibody against Vascular Endothelial Growth Factor Receptor-2
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